18 completed, 8 unknown, 6 not yet recruiting, 5 recruiting. 26 Not applicable, 2 Phase 2, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 26 | Completed 11, Unknown 7, Not yet recruiting 5, Recruiting 2, Terminated 1 |
| Phase 2 | 2 | Completed 1, Suspended 1 |
| Phase 1 | 1 | Suspended 1 |
| Phase 3 | 1 | Completed 1 |
Follow Open Heart Surgery: new trials by email Literature Review of Open Heart Surgery trials Research Report on Open Heart Surgery
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Post-surgical Delirium in Patients Undergoing Open Heart Surgery. Open heart surgery - Delirium, Open Heart Surgery | Not yet recruiting | University of Alexandria | 300 | 2028-10-01 | 2025-04-03 | |
| Does the Pericardial Closure Reduces Early Right Ventricular Dysfunction After Cardiac Surgery: A Randomized Controlled Trial close pericardium - Effect of Pericardial Closure on the Right Ventricular Function Post Cardiac Surgery, Open Heart Surgery | Not applicable | Not yet recruiting | Assiut University | 90 | 2026-12-10 | 2026-09-23 |
| Localized Evidence of Cytokine Adsorption Therapy During Pediatric Cardiac Surgery: A Single Center Randomized Controlled Trial (LEAT) Hemoadsorption (Jafron HA-60/HA380) - Congenital Heart Disease, Open Heart Surgery | Not applicable | Not yet recruiting | Norfaniza Zabidi | 120 | 2026-10-01 | 2026-08-18 |
| The Effect of Virtual Reality Headsets on Pain, Anxiety, Patient Satisfaction, and Physiological Parameters in Patients Undergoing Open-Heart Surgery Virtual Reality Glasses - Pain After Surgery, Pain and Anxiety | Not applicable | Recruiting | Dokuz Eylul University | 44 | 2026-09-30 | 2026-11-03 |
| Bleeding Management İn Open Heart Surgery Blood Product - Thromboelastography (TEG), Open Heart Surgery | Not applicable | Not yet recruiting | Serkan Uckun | 140 | 2026-04-01 | 2026-01-26 |
| Dose for Reversal of Heparin After Cardiopulmonary Bypass Protamine sulfate - Open Heart Surgery | Not applicable | Recruiting | Sohag University | 195 | 2026-03-01 | 2026-05-05 |
| Mindfulness-Based Nursing Care and Anxiety in Open Heart Surgery Patients Mindfulness-Based Nursing Intervention Group, Standard Care Control Group - Open Heart Surgery, Anxiety | Not applicable | Not yet recruiting | Mersin University | 60 | 2026-02-10 | 2026-02-09 |
| Effect of a Cooling Helmet on Postoperative Cognitive Dysfunction in Adults Undergoing Open-Heart Surgery Cooling Helmet With Cold Water Circulation, Cooling Helmet With Room-Temperature Water Circulation - Postoperative Cognitive Complications, Open Heart Surgery | Not applicable | Completed | Universitas Indonesia | 153 | 2025-11-30 | 2026-07-09 |
| The Effect of Rapid Relaxation Exercise and Cold Application on Pain, Anxiety, and Satisfaction Before Chest Tube Removal Cold Application, Rapid Relaxation Exercise - Open Heart Surgery | Not applicable | Not yet recruiting | Ataturk University | 87 | 2025-11-15 | 2025-11-25 |
| Propranolol Treatment for Postoperative Chylothorax Propranolol Hydrochloride, Placebo - Postoperative Chylothorax, Congenital Heart Disease | Phase 1 / Phase 2 | Suspended | June Wu | 50 | 2025-09-09 | 2026-05-15 |
| The Relationship Between Hypotension and Tissue O2 in Invasive Eadyn During Anesthesia Induction in Open Heart Surgery mostcare hemodynamic monitor, Masimo NIRS, Hemodynamic Measurements on Standart Monitoring - Post-induction Hypotension, Eadyn | Recruiting | Haseki Training and Research Hospital | 40 | 2025-09-01 | 2026-09-21 | |
| Evaluation of Optic Nerve Sheath Diameter Changes During Cardiopulmonary Bypass in Open Heart Surgery Ultrasonography of the Optic Nerve Sheath - Open Heart Surgery, Cardiopulmonary Bypass | Completed | Medipol University | 40 | 2025-06-10 | 2025-11-28 | |
| CTICU Device Study CRUISE CRUISE CTICU CareTaker Vitalstream Device, CRUISE CTICU CNAP Device, CRUISE CTICU Edwards Clearsight Device - Open Heart Surgery | Enrolling by invitation | Hernando Gomez | 50 | 2025-06-03 | 2026-03-06 | |
| Comparison of IV Analgesia, Thoracic Epidural Analgesia, and ESP Block for Chronic Pain After Open Heart Surgery Intravenous Analgesia, Thoracic Epidural Analgesia (TEA), Erector Spinae Plane Block (ESPB) - Chronic Postoperative Pain, Open Heart Surgery | Completed | Karadeniz Technical University | 90 | 2025-02-15 | 2026-11-12 | |
| The Predictive Value of Doppler Based Renal Ultrasound and Urinary Oxygen Tension for Prediction of Acute Kidney Injury After Open Heart Surgery Renal resistive index, Renal Artery Pulsatility Index, Urinary oxygen tension (PUO2) - Doppler-Based Renal Ultrasound, Urinary Oxygen Tension | Recruiting | Tanta University | 50 | 2024-10-01 | 2025-06-25 | |
| Comparison of the Factors Affecting PSI and BIS Values in Monitoring Anesthetic Depth During Open-Heart Surgery anesthesia depth monitorizing, awareness - BIS-EEG, PSI | Active not recruiting | Kocaeli University | 46 | 2024-01-18 | 2025-06-29 | |
| The Effect of Neurophysiological Facilitation Techniques on Health Parameters in Early Stages After Open Heart Surgery Phase 1 cardiac rehabilitation, Neurophysiological facilitation techniques - Open Heart Surgery, Cardiovascular Disease | Not applicable | Unknown | Dogus Universitesi | 32 | 2024-01-01 | 2024-08-13 |
| Ilofotase Alfa for Prevention of Renal Damage After Cardiac Surgery Ilofotase alfa, Placebo - Open Heart Surgery | Phase 2 | Completed | AM-Pharma | 271 | 2023-12-19 | 2026-09-29 |
| The Effect of Video-supported Education on Anxiety Levels and the ICU Experience Education with Video - Open Heart Surgery | Not applicable | Completed | Zeynep Turak | 110 | 2023-10-01 | 2025-12-15 |
| The Effect of Video Game-Based Exercises After Open Heart Surgery video based exercises - Open Heart Surgery, Physical Fitness | Not applicable | Unknown | Sanko University | 28 | 2023-09-11 | 2024-01-12 |
Showing 20 of 41. Sign in to see all of them.
Anxiety Disorders (5) · Heart Defects, Congenital (2) · Pain (2) · Pain, Postoperative (2) · Patient Satisfaction (2) · Acute Kidney Injury (1) · Agnosia (1) · Cardiovascular Diseases (1) · Caregiver Burden (1) · Chylothorax (1) · Delirium (1) · Heart Diseases (1) · Heart Valve Diseases (1) · Hemorrhage (1) · Hypothermia (1)
Pathological Conditions, Signs and Symptoms (9) · Mental Disorders (8) · Pathologic Processes (6) · Signs and Symptoms (6) · Neurologic Manifestations (5) · Behavior (4) · Postoperative Complications (4) · Cardiovascular Diseases (3) · Nervous System Diseases (3) · Cardiovascular Abnormalities (2) · Congenital Abnormalities (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (2) · Health Behavior (2) · Heart Diseases (2) · Neurobehavioral Manifestations (2)
2-Propanol (1) · Acetaminophen (1) · Adjuvants, Pharmaceutic (1) · Analgesia (1) · Anesthetics, Local (1) · Congresses as Topic (1) · Educational Status (1) · Enhanced Recovery After Surgery (1) · Epinephrine (1) · Ischemic Preconditioning (1) · Ketorolac (1) · Magnesium Sulfate (1) · Propofol (1) · Propranolol (1) · Protamines (1)
Assiut University (5) · Trakya University (2) · University of Beykent (2) · AM-Pharma (1) · Ain Shams University (1) · Ataturk University (1) · Bahria University (1) · Cairo University (1) · Dogus Universitesi (1) · Dokuz Eylul University (1) · Hasan Kalyoncu University (1) · Haseki Training and Research Hospital (1) · Hernando Gomez (1) · June Wu (1) · Karadeniz Technical University (1)
Turkey (Türkiye) (15) · Egypt (10) · United States (3) · Belgium (1) · Germany (1) · India (1) · Indonesia (1) · Netherlands (1) · Pakistan (1) · Switzerland (1) · Taiwan (1) · Thailand (1) · United Kingdom (1) · Vietnam (1)
Asmaa S Farghaly, MD (1) · Ayla Yava, Prof, RN (1) · Ayse Baysal, MD (1) · Emad Kamel Said, MD (1) · Esra Akdeniz, BSN (1) · Hernando Gomez, MD (1) · June Wu, MD (1) · Kadiriye Pehlivan, MSc RN (1) · Paul Gurbel, MD (1)
PMID 10673877, PMID 11089751, PMID 12091180, PMID 12185431, PMID 12626284, PMID 14616327, PMID 15994402, PMID 17038199, PMID 19629309, PMID 20643803, PMID 22221684, PMID 23939326, PMID 23993292, PMID 24182820, PMID 27878573, PMID 30356595, PMID 31994405, PMID 33103326, PMID 39614857, PMID 40152923, PMID 41782082, PMID 42766022, PMID 8306041