109 completed, 48 unknown, 19 recruiting, 11 not yet recruiting. 131 Not applicable, 32 Phase 4, 5 Phase 2, 5 Phase 3, 1 Early Phase 1.
Follow Nerve Block: new trials by email Literature Review of Nerve Block trials Research Report on Nerve Block
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| LIA vs. LIA + ACB-iPACK Block for Total Knee Arthroplasty Local infiltration analgesia, Ultrasound-guided adductor canal block - Nerve Block, Neuromuscular Blockade | Not applicable | Not yet recruiting | Women's College Hospital | 60 | 2027-01-01 | 2025-07-16 |
| Blast-related Regional Anaesthesia and Peripheral nerVe Injury Evaluation Standardized Multimodal Analgesia, Ultrasound-Guided Regional Anaesthesia - Nerve Block, Nerve Blocks | Not applicable | Not yet recruiting | Ukrainian Society of Regional Anesthesia and Pain Therapy | 150 | 2026-12-23 | 2026-10-19 |
| Machine Learning Prediction of Spinal Anaesthesia Block Duration Anesthesia, Spinal, Nerve Block | Not yet recruiting | Specialized Medical Center (SMC) | 255 | 2026-12-01 | 2026-09-25 | |
| Nerve Blocks or Combat Trauma: What Drives Peripheral Nerve Injury? Combat-Related Limb Injury, Nerve Block | Not yet recruiting | Ukrainian Society of Regional Anesthesia and Pain Therapy | 1000 | 2026-10-31 | 2026-10-09 | |
| Classic Versus Interfascial Axillary Block in Hand, Wrist, and Forearm Surgery Classic Axillary Block, Interfascial Axillary Block - Nerve Block, Regional Anesthesia | Not applicable | Not yet recruiting | Bursa Yuksek Ihtisas Training and Research Hospital | 110 | 2026-10-15 | 2026-09-21 |
| BLOCK-TRAUMA Study Polytrauma, Regional Anaesthesia | Completed | Ukrainian Society of Regional Anesthesia and Pain Therapy | 500 | 2026-10-01 | 2026-10-02 | |
| QLESP Block for Pain Control in Robotic Partial Nephrectomy ropivacaine (local infiltration), ropivacaine - Renal Cell Carcinoma (Kidney Cancer), Postoperative Pain | Not applicable | Recruiting | Huazhong University of Science and Technology | 120 | 2026-09-22 | 2026-09-25 |
| Regional Nerve Block for Upper Extremity Surgery in Patients With Sarcopenia sarcopenia, Non-sarcopenia, General Anesthesia - Sarcopenia, Nerve Block | Not yet recruiting | Chang Gung Memorial Hospital | 150 | 2026-09-01 | 2026-08-11 | |
| SPSIP Block for Pain Control After Breast Reduction Surgery Ultrasound-Guided Serratus Posterior Superior Intercostal Plane Block, Standard Perioperative Pain Treatment - Postoperative Pain Breast Reduction, Mammaplasty | Not applicable | Recruiting | Cumhuriyet University Hospital | 80 | 2026-08-24 | 2026-08-25 |
| Analgesic Effects of Retro-superior Costotransverse Ligament Space Block for Video-assisted Thoracoscopic Surgery Ultrasound-guided retro-SCTLB, Ultrasound-guided TPVB - Nerve Block, Thoracoscopic Radical Resection of Lung Cancer | Not applicable | Recruiting | Nanjing First Hospital, Nanjing Medical University | 130 | 2026-08-05 | 2026-08-06 |
| Comparison Between Ultrasound Guided Quadratus Lumborum Block and Erector Spinae Plane Block as an Analgesic Modality in Renal Transplant Donors Renal transplantation - Renal Transplantation, Nerve Block | Not applicable | Active not recruiting | Ain Shams University | 50 | 2026-07-01 | 2026-08-06 |
| Minimal Effective Volume 90% for Double-injection Costoclavicular Block Ultrasound-guided double-injection costoclavicular nerve block with same previous volume, Ultrasound-guided double-injection costoclavicular nerve block with lower volume - Brachial Plexus Blocks, Lidocaine | Phase 4 | Recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 60 | 2026-06-16 | 2026-07-07 |
| Shoulder RA Survey Study Nerve Block | Recruiting | University Health Network, Toronto | 140 | 2026-06-05 | 2026-07-31 | |
| Erector Spinae Block vs. Placebo Block Study Erector spinae plane block, Placebo Block - Breast Cancer, Nerve Block | Not applicable | Not yet recruiting | Women's College Hospital | 60 | 2026-06-01 | 2025-07-16 |
| Liposomal Bupivacaine Versus Ropivacaine With Perineural Dexamethasone or Dexmedetomidine as Adjuncts for Adductor Canal Block Combined With IPACK Block in Total Knee Arthroplasty Liposomal bupivacaine (LB), Ropivacaine with Perineural Dexamethasone, Ropivacaine with Perineural Dexmedetomidine - Total Knee Anthroplasty, Nerve Block | Not applicable | Completed | Huazhong University of Science and Technology | 90 | 2026-04-09 | 2026-10-06 |
| Training Non-Anesthesia Personnel to Perform Nerve Blocks in Microgravity Simulated microgravity, Normal earth gravity - Nerve Block, Regional Anesthesia | Not applicable | Completed | Nova Scotia Health Authority | 30 | 2026-03-20 | 2026-09-30 |
| Comparison Between External Oblique Intercostal Plane Block and Rectus Sheath Block Combined With Transversus Abdominis Plane Block External intercostal plane puncture, control group (nalbuphine), the single-puncture technique of (rectus sheath block) combined with (Transversus abdominis plane block) - Pain Management, Anesthesia , Analgesia | Not applicable | Not yet recruiting | Minia University | 60 | 2026-01-20 | 2026-02-03 |
| Ultrasound Guided External Oblique Intercostal Plane Block Versus Erector Spinae Block for Post Hepatectomy Pain Ultrasound guided external oblique intercostal (EOI) plane block, Ultrasound guided erector spinae block - Pain; Cancer, Hepatectomy | Not applicable | Not yet recruiting | National Cancer Institute, Egypt | 52 | 2026-01-15 | 2026-02-02 |
| Near Remote Method to Guide Performance of Regional Anesthesia Real time 'near remote' guidance of regional blocks - Anesthesia, Analgesia | Recruiting | Dr. Glenio Mizubuti (MD, PhD) | 200 | 2026-01-01 | 2025-07-31 | |
| Lumbar-Sacral Plexus Block vs Fascia Iliaca Block Plus Low-Dose Spinal Anesthesia for Femoral Neck Fracture Surgery Lumbar and Sacral Plexus Block, Fascia Iliaca Block Combined with Low-Dose Spinal Anesthesia - Femoral Neck Fractures, Nerve Block | Not applicable | Active not recruiting | Bursa Yuksek Ihtisas Training and Research Hospital | 60 | 2025-12-30 | 2026-10-14 |
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Pain, Postoperative (52) · Agnosia (32) · Pain (11) · Hip Fractures (5) · Acute Pain (4) · Bites and Stings (3) · Breast Neoplasms (3) · Neuralgia (3) · Cough (2) · Emergence Delirium (2) · Femoral Neck Fractures (2) · Peripheral Nerve Injuries (2) · Shoulder Pain (2) · Amputation, Traumatic (1) · Back Pain (1)
Pathological Conditions, Signs and Symptoms (96) · Signs and Symptoms (94) · Neurologic Manifestations (91) · Pathologic Processes (57) · Postoperative Complications (56) · Pain (54) · Nervous System Diseases (41) · Neurobehavioral Manifestations (35) · Perceptual Disorders (33) · Wounds and Injuries (16) · Neoplasms (10) · Neoplasms by Site (10) · Fractures, Bone (8) · Hip Injuries (7) · Leg Injuries (7)
Ropivacaine (25) · Bupivacaine (20) · Dexamethasone (8) · Nerve Block (7) · Anesthesia, Spinal (6) · Dexmedetomidine (6) · Lidocaine (6) · Sodium Chloride (6) · Anesthesia, General (5) · Morphine (5) · Tramadol (5) · Analgesia, Patient-Controlled (4) · Dental Occlusion (4) · Epinephrine (4) · Saline Solution (4)
Bursa Yuksek Ihtisas Training and Research Hospital (12) · Cui Xulei (6) · Peking Union Medical College Hospital (6) · Ain Shams University (4) · Ankara City Hospital Bilkent (4) · Bozyaka Training and Research Hospital (4) · Huazhong University of Science and Technology (4) · Mogilev Regional Clinical Hospital (4) · Giresun University (3) · Oslo University Hospital (3) · Ukrainian Society of Regional Anesthesia and Pain Therapy (3) · University of Castilla-La Mancha (3) · Affiliated Hospital of Nantong University (2) · Ankara University (2) · Antalya Training and Research Hospital (2)
Turkey (Türkiye) (42) · China (37) · United States (19) · Canada (18) · Denmark (7) · Egypt (7) · Belgium (5) · Belarus (4) · France (4) · Norway (4) · Brazil (3) · Italy (3) · South Korea (3) · Spain (3) · Taiwan (3)
Lidziya Muzyka (3) · Valery Piacherski, Ph.D. (3) · Yuguang Huang, MD. (3) · Brian M Ilfeld, M.D., M.S. (2) · Giorgio Danelli, MD (2) · Kasper H Thybo, MD (2) · Melinda Seering, MD (2) · Yuguang Huang, MD (2)
PMID 10927999, PMID 1550287, PMID 20705642, PMID 21655015, PMID 22745114, PMID 23053464, PMID 23392233, PMID 23685099, PMID 25051144, PMID 26079353, PMID 26475166, PMID 26897453, PMID 27341450, PMID 27547910, PMID 27555162, PMID 27730633, PMID 27755488, PMID 27811526, PMID 28554709, PMID 28564673, PMID 28991711, PMID 29746445, PMID 29847387, PMID 29890381, PMID 30197534, PMID 30419966, PMID 30902911, PMID 30923253, PMID 30999197, PMID 31088120, PMID 31119551, PMID 31203111, PMID 31315670, PMID 31343504, PMID 31455249, PMID 31570245, PMID 31591018, PMID 31908520, PMID 31935572, PMID 32009005, PMID 32032103, PMID 32540878, PMID 32757999, PMID 32892818, PMID 33036554, PMID 33831768, PMID 33907461, PMID 34171466, PMID 34432155, PMID 34471571
2016 (2), 2017 (1), 2023 (1), 2025 (1)