17 completed, 3 recruiting, 3 unknown, 2 not yet recruiting. 28 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 28 | Completed 17, Recruiting 3, Unknown 3, Not yet recruiting 2, Terminated 2, Enrolling by invitation 1 |
Follow Muscle Hypotonia: new trials by email Literature Review of Muscle Hypotonia trials Research Report on Muscle Hypotonia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Impact of Ventilator Synchrony on Muscle Relaxant Consumption and Surgeon Satisfaction During Laparoscopic Cholecystectomy. Non-Synchronized Group (Control), Synchronized group - Muscle Relaxant Consumption, Mechanical Ventilation | Not applicable | Not yet recruiting | Hitham Mohammed Aly Elsayed | 60 | 2026-08-01 | 2026-06-15 |
| Test of Aquatic Mobility of SMA Infants Mobility study in dry conditions, Mobility study in water conditions - Infantile Spinal Muscular Atrophy | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 15 | 2025-06-26 | 2025-11-21 |
| Muscle Relaxant Effect and Safety of Mivacurium Chloride and Succinylcholine for Bronchoscopy mivacurium chloride, succinylcholine - Anesthesia, Bronchoscopy | Not applicable | Not yet recruiting | Peng Liang | 240 | 2024-11-20 | 2024-11-29 |
| Long-term Evaluation of Nasopharyngeal Airway in Hypotonia Self-Supporting Nasopharyngeal Airway (ssNPA) - Hypotonia, Muscle, Obstructive Sleep Apnea | Not applicable | Enrolling by invitation | University of Michigan | 40 | 2024-10-23 | 2025-12-02 |
| The Potential Protective Effect of Using Muscle Relaxants During Electroporation Ablation (PFA) Propofol, Rocuronium - Kidney Failure, Acute, Myopathy; Drugs | Not applicable | Recruiting | 4th Military Clinical Hospital with Polyclinic, Poland | 32 | 2024-08-01 | 2024-11-27 |
| Use of Muscle Relaxants in Parotidectomy Operation With Neuromonitoring Group A - Muscle Relaxants Used, Group B - No Muscle Relaxants - Intubation; Difficult or Failed, Muscle Relaxation | Not applicable | Completed | Bezmialem Vakif University | 40 | 2022-06-30 | 2023-03-14 |
| Muscle Relaxants and Laryngeal Local Anesthetics for Laryngeal Mask Airway Insertion Decreasing Propofol in Elderly 10% lidocaine spray, Placebo of lidocaine spray, Cisatracurium - Anesthesia, General | Not applicable | Completed | Chang Gung Memorial Hospital | 96 | 2022-04-12 | 2024-02-06 |
| Pilot Study of a Self-Supporting Nasopharyngeal Airway in Hypotonia ssNPA - Sleep Apnea, Obstructive, Hypotonia | Not applicable | Completed | University of Michigan | 2 | 2021-09-01 | 2023-12-28 |
| Vestibular Stimulation and Neurodevelopmental Technique on Hypotonic Cerebral Palsy While Controlling the Gender Vestibular stimulation, Neck Control facilitation exercises - Cerebral Palsy, Hypotonia | Not applicable | Completed | Riphah International University | 24 | 2021-05-30 | 2022-02-22 |
| Down Syndrome and Effects of Foot Muscle Exercise Foot Muscle Exercise Protocol, Arch Support Insole and One Leg Balance Activities - Pes Planus Down Syndrome Patients | Not applicable | Completed | Ziauddin University | 47 | 2021-04-22 | 2022-02-23 |
| Small Doses Muscle Relaxant in General Anesthesia Atracurium Besylate regular dose, Atracurium Besylate minial dose - Muscle Relaxant | Not applicable | Recruiting | Mansoura University | 60 | 2020-04-22 | 2026-10-15 |
| Osteopathic Treatment on Motor Development of Hypotonic Infants. ostheopathy, simulated osteopathic treatment - Hypotonia | Not applicable | Terminated | Centre Hospitalier Intercommunal Creteil | 40 | 2018-12-13 | 2026-06-29 |
| North Carolina Genomic Evaluation by Next-generation Exome Sequencing, 2 Pre-visit prep, usual care + exome seq - Epilepsy; Seizure, Neuromuscular Diseases | Not applicable | Completed | University of North Carolina, Chapel Hill | 548 | 2018-09-28 | 2025-05-13 |
| Effect of Trunk Support on Academic Engagement of Children With Severe Disability customized posture support - Cerebral Palsy, Traumatic Brain Injury | Not applicable | Completed | University of Hartford | 10 | 2018-05-31 | 2022-05-26 |
| Muscle Relaxants on Efficacy of LMA Insertion rocuronium, saline - Anesthesia Intubation Complication | Not applicable | Completed | Daegu Catholic University Medical Center | 128 | 2018-04-20 | 2019-10-25 |
| Efficacy and Safety of Poly-L-lactic Acid Poly-L-lactic acid - Sculptra - Flaccidity, Muscle | Not applicable | Completed | Galderma Brasil Ltda. | 70 | 2017-08-21 | 2018-03-29 |
| Effect of Intraoperative Muscle Relaxation Depth on Postoperative Sore Throat and Hoarseness After General Anesthesia Rocuronium(deep), Rocuronium(moderate) - Sore Throat | Not applicable | Unknown | SMG-SNU Boramae Medical Center | 206 | 2017-08-01 | 2018-06-26 |
| Evaluation and Comparison of Women Pelvic Floor With and Without Sexual Dysfunction (Vaginismus) Evaluation and Comparison of women pelvic floor with and without sexual dysfunction, The physiotherapeutic treatment - Vaginismus, Sexual Dysfunctions | Not applicable | Completed | Faculdade de Ciências Médicas da Santa Casa de São Paulo | 60 | 2017-02-01 | 2019-10-07 |
| Pediatric Inguinal Hernia Repair: Are Muscle Relaxants Necessary? Endotracheal Intubation vs Laryngeal Mask Airway ETT, Proseal LMA, Rocuronium - Inguinal Hernia, Endotracheal Intubation | Not applicable | Completed | Maltepe University | 80 | 2016-03-01 | 2016-06-01 |
| Mapping Human Muscle Satellite Cell Fate By Real-Time Imaging muscle biopsy - Flaccid Muscle Tone | Not applicable | Completed | Purdue University | 7 | 2016-02-01 | 2017-06-20 |
Showing 20 of 28. Sign in to see all of them.
Cerebral Palsy (3) · Down Syndrome (2) · Sleep Apnea, Obstructive (2) · Acute Kidney Injury (1) · Agnosia (1) · Arrhythmias, Cardiac (1) · Asthenia (1) · Autism Spectrum Disorder (1) · Brain Injuries, Traumatic (1) · Butyrylcholinesterase deficiency (1) · Chromosome Aberrations (1) · Chronic Pain (1) · Congenital Abnormalities (1) · Dwarfism, Pituitary (1)
Nervous System Diseases (28) · Neurologic Manifestations (28) · Neuromuscular Manifestations (28) · Pathological Conditions, Signs and Symptoms (28) · Signs and Symptoms (28) · Central Nervous System Diseases (6) · Brain Diseases (5) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (5) · Musculoskeletal Diseases (5) · Neurobehavioral Manifestations (5) · Genetic Diseases, Inborn (4) · Respiratory Tract Diseases (4) · Abnormalities, Multiple (3) · Brain Damage, Chronic (3) · Chromosome Disorders (3)
Rocuronium (5) · Propofol (3) · Sodium Chloride (2) · cisatracurium (2) · Acupuncture Therapy (1) · Anesthesia, General (1) · Blood Specimen Collection (1) · Bupivacaine (1) · Control Groups (1) · Manual Lymphatic Drainage (1) · Massage (1) · Mivacurium (1) · Remifentanil (1) · Saline Solution (1) · Sevoflurane (1)
University of Michigan (2) · 4th Military Clinical Hospital with Polyclinic, Poland (1) · Assistance Publique - Hôpitaux de Paris (1) · Bezmialem Vakif University (1) · Centre Hospitalier Intercommunal Creteil (1) · Chang Gung Memorial Hospital (1) · Daegu Catholic University Medical Center (1) · Faculdade de Ciências Médicas da Santa Casa de São Paulo (1) · Federal University of São Paulo (1) · Galderma Brasil Ltda. (1) · Hitham Mohammed Aly Elsayed (1) · Mackay Memorial Hospital (1) · Maltepe University (1) · Mansoura University (1) · Peng Liang (1)
United States (5) · Brazil (4) · France (2) · Germany (2) · Pakistan (2) · South Korea (2) · Taiwan (2) · Turkey (Türkiye) (2) · Belgium (1) · Egypt (1) · Hong Kong (1) · Poland (1) · Saudi Arabia (1) · Spain (1)
Alessandra Haddad (1) · Antonio Romero Berrocal, MD,PhD (1) · Carine Wiesiolek, PhD (1) · Chung Yung-Tai, MD (1) · David A Zopf, MD (1) · Doris M Hexsel (1) · Eugene Kim, MD, PhD (1) · Hung Yu-Ting, MD (1) · Ismail Sumer, MD (1) · Jeannette T Bensen, Ph.D (1) · Jee-eun Chang, M.D (1) · Jonathan S Berg, MD, PhD (1) · Karla F Lambertz, PhD (1) · Kuang H Cheng, Msc (1)
PMID 20661199, PMID 23122973, PMID 24565391, PMID 24708453, PMID 28387017, PMID 30626406, PMID 34127041, PMID 39315524, PMID 41566470
R61HL151952 (1), U01HG006487 (1)