40 completed, 10 recruiting, 9 unknown, 8 terminated. 47 Not applicable, 8 Phase 3, 6 Phase 2, 2 Phase 1, 2 Phase 4.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Restoring Independence With Stimulation-Enhanced Treatment for People With Functional Neurological Disorder Stimulation-Enhanced Physical Therapy, Active Comparator - Functional Neurological Disorder, Conversion Disorder | Not applicable | Not yet recruiting | University of Auckland, New Zealand | 60 | 2026-11-01 | 2026-08-18 |
| Imaging Assessment of Swallowing and Speech Muscles in Inclusion Body Myositis IBM, Inclusion Body Myositis | Recruiting | Johns Hopkins University | 30 | 2026-11-01 | 2026-10-28 | |
| Telerehabilitation for Post-Stroke Hand Function Technology-Supported Hand Training, Pamphlet-Supported Hand Activity - Stroke | Not applicable | Recruiting | University of Michigan | 22 | 2026-10-13 | 2026-10-15 |
| STRIDE: Strength of The Calf Muscles and Their Role In Declining Effectiveness of Movement With Aging No intervention (observational study) - Sarcopenia, Aging | Not yet recruiting | University of Leicester | 200 | 2026-08-01 | 2026-07-24 | |
| Silkworm Pupa Powder Improves Alzheimer's Disease Silkworm pupa powder - Alzheimer Disease, Sarcopenia | Not applicable | Not yet recruiting | Zhejiang Provincial Tongde Hospital | 100 | 2026-06-01 | 2026-06-10 |
| At Home Wearable Sensors and Smartphone for Stroke Survivors With Upper Limb Motor Challenges. mHealth - Stroke | Not applicable | Recruiting | Spaulding Rehabilitation Hospital | 50 | 2026-04-20 | 2026-07-13 |
| TCM Formula vs. HMB in Pre-Frail Elders: Muscle Strength and Bone Status TCM Formula, HMB (beta-Hydroxy-beta-methylbutyrate) - Pre-Frailty, Sarcopenia | Phase 2 | Recruiting | Tri-Service General Hospital (TSGH) | 90 | 2026-04-02 | 2026-05-19 |
| Post Operative Use of Neuromuscular Electrical Stimulation (NMES) Device for ACLR Patients Zynex NexWave Electrotherapy Device - ACL Reconstruction, ACL Surgery | Not applicable | Enrolling by invitation | University of Kansas Medical Center | 25 | 2026-02-10 | 2026-03-17 |
| A Study of Silkworm Pupa Powder Intervention in the Nutritional Status of Patients With Alzheimer's Disease. Silkworm pupa powder, Placebo - AD - Alzheimer's Disease, Sarcopenia | Not applicable | Recruiting | Zhejiang Hospital | 200 | 2025-11-23 | 2026-01-02 |
| Passive Robots for Stroke Rehabilitation: A Feasibility Study Functional Training with SepaRRo and NeuRRoFES - Stroke | Not applicable | Recruiting | University of Michigan | 4 | 2025-11-05 | 2025-11-10 |
| Neuromuscular Electrical Stimulation in Critically Ill Patients Aged 80 and Over Medium Frequency Neuromuscular Electrical Stimulation (NMES), Standard physical therapy - Intensive Care Units (ICUs), Muscle Atrophy or Weakness | Not applicable | Not yet recruiting | Universidad de La Frontera | 30 | 2025-09-01 | 2025-08-17 |
| Silkworm Pupa Powder Improves Dementia. Silkworm pupa powder, Placebo - Alzheimer Disease(AD), Sarcopenia | Not applicable | Recruiting | Zhejiang Provincial Tongde Hospital | 300 | 2025-04-10 | 2026-06-08 |
| Evaluation of the Hospital Pathway for Frail Elderly Patients Hospitalised for Pathologies Leading to Medical Decompensation Frail Elderly People Hospitalized | Completed | Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer | 310 | 2025-02-28 | 2025-11-20 | |
| A Study of Silkworm Pupa Powder Intervention in the Nutritional Status of Patients with Alzheimer's Disease. Silkworm pupa powder, Placebo - Alzheimer Disease (AD), Sarcopenia | Not applicable | Not yet recruiting | Yanbu Ke | 100 | 2025-01-02 | 2025-01-13 |
| AI Based Muscular Ultrasound to Assess Intensive Care Unit-acquired Weakness Neuromuscular Ultrasound - Intensive Care Unit-acquired Weakness, Artifical Intelligence | Completed | Jena University Hospital | 64 | 2024-10-01 | 2026-08-18 | |
| Repetitive Action Simulation Circuit Training to Reduce Arm Weakness After a Stroke Upper Extremity Action Simulation Circuit Training - Stroke, Hemiparesis of the Upper Limb Following Stroke | Not applicable | Completed | Towson University | 5 | 2024-09-17 | 2026-08-19 |
| Metformin and Muscle Recovery Metformin, Placebo - Muscle Atrophy or Weakness | Early Phase 1 | Recruiting | University of Utah | 50 | 2024-09-01 | 2025-12-05 |
| The Influence of Oral Contraceptives During Disuse Wrist/hand immobilization - Oral Contraceptives, Rehabilitation | Not applicable | Completed | University of Central Florida | 41 | 2024-01-26 | 2025-05-22 |
| YOOMI: Effect of Gamified Physical Therapy Exercise Software on Inpatient Mobility Yoomi Physical Therapy Software - Weakness, Muscle, Delirium in Old Age | Not applicable | Completed | Rutgers, The State University of New Jersey | 30 | 2023-11-29 | 2026-08-07 |
| Ultrasound Characteristics of the Salivary Glands in Patients With Rheumatoid Arthritis Ultrasound of the salivary glands, Measurement of salivary flow, A Schirmer test - Rheumatoid Arthritis, Sjogren's Syndrome | Not applicable | Unknown | University Hospital, Clermont-Ferrand | 210 | 2023-02-02 | 2023-03-23 |
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Muscular Atrophy (14) · Sarcopenia (10) · Stroke (9) · Fatigue (6) · Motor Activity (6) · Atrophy (5) · Critical Illness (5) · Muscle Weakness (5) · Pain (5) · Paresis (5) · Respiratory Insufficiency (5) · Sepsis (5) · Alzheimer Disease (4) · Muscular Diseases (4)
Pathological Conditions, Signs and Symptoms (77) · Signs and Symptoms (76) · Nervous System Diseases (48) · Neurologic Manifestations (38) · Neuromuscular Manifestations (26) · Pathological Conditions, Anatomical (23) · Central Nervous System Diseases (19) · Atrophy (18) · Pathologic Processes (17) · Brain Diseases (15) · Musculoskeletal Diseases (15) · Cardiovascular Diseases (11) · Respiratory Tract Diseases (11) · Vascular Diseases (11) · Behavior (10)
Exercise (3) · 3-(2,2,2-trimethylhydrazine)propionate (2) · Electric Stimulation (2) · Methylphenidate (2) · Walking (2) · coenzyme Q10 (2) · Cognitive Training (1) · Conservative Treatment (1) · Core Stability (1) · Creatine (1) · Droxidopa (1) · Exercise Therapy (1) · Mannitol (1) · Metformin (1) · Modafinil (1)
Gerald Supinski (2) · National Institute of Neurological Disorders and Stroke (NINDS) (2) · Promomed, LLC (2) · The Cleveland Clinic (2) · University of Michigan (2) · Zhejiang Provincial Tongde Hospital (2) · Amsterdam UMC, location VUmc (1) · Assistance Publique - Hôpitaux de Paris (1) · Athanasios Ellinoudis (1) · Boston Medical Group (1) · Brigham and Women's Hospital (1) · CES University (1) · Catherine Buettner (1) · Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer (1) · Centre Hospitalier Universitaire de Nīmes (1)
United States (36) · China (5) · France (5) · Russia (3) · Switzerland (3) · United Kingdom (3) · Canada (2) · Colombia (2) · Italy (2) · Spain (2) · Taiwan (2) · Turkey (Türkiye) (2) · Brazil (1) · Chile (1) · Czechia (1)
Chandramouli Krishnan, PT, PhD (2) · Aaron Hamilton, MD (1) · Abdullah Z AlQahtani, MD MPH (1) · Anuj K Dalal, MD (1) · Athanasios Ellinoudis, PhD (1) · Billie Schultz, MD (1) · Brian C Clark, PhD (1) · Carlos Centeno Cortes, MD, Phd (1) · Carole E Aubert, MD, MSc (1) · Catherine Buettner, MD, MPH (1) · Cathy Stinear (1) · Claudio Borghi, MD, PhD (1) · Cristina Amaya (1)
PMID 12472328, PMID 17990291, PMID 18570643, PMID 18816600, PMID 19446324, PMID 19623052, PMID 20046132, PMID 20406506, PMID 22147819, PMID 22573483, PMID 23497667, PMID 24257969, PMID 24326693, PMID 25466314, PMID 25703957, PMID 25715872, PMID 25741894, PMID 25922111, PMID 26131835, PMID 26637645, PMID 26735540, PMID 27053291, PMID 27168433, PMID 27485469, PMID 27538531, PMID 28251398, PMID 28342828, PMID 28494751, PMID 29914808, PMID 30003579, PMID 31100700, PMID 32266379, PMID 32723298, PMID 33208658, PMID 34097055, PMID 37624389, PMID 37907858, PMID 38710920, PMID 40066282, PMID 41187315, PMID 42080459
2008 (1), 2025 (1), K23AR055664 (1), R01AG044424 (1), R01EB027777 (1), R21AG077125 (1)