14 completed, 2 recruiting, 1 terminated. 7 Not applicable, 3 Phase 1, 2 Phase 3, 1 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 6, Recruiting 1 |
| Phase 1 | 3 | Completed 2, Terminated 1 |
| Phase 3 | 2 | Completed 2 |
| Phase 2 | 1 | Completed 1 |
| Phase 4 | 1 | Completed 1 |
Follow Migraines: new trials by email Literature Review of Migraines trials Research Report on Migraines
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Mind Body Intervention for Chronic Migraine Headaches Mind-Body Intervention - Migraines, Chronic Pain | Not applicable | Recruiting | Beth Israel Deaconess Medical Center | 10 | 2024-11-15 | 2026-03-17 |
| Unhide® Project: A Digital Health Platform to Collect Lifestyle Data for Brain Inflammation Research Post-Acute COVID-19 Syndrome, ME/CFS | Recruiting | Brain Inflammation Collaborative | 10000 | 2023-07-05 | 2026-01-22 | |
| A Trial to Evaluate the Efficacy, Safety and Tolerability of Subcutaneous TRV250 Part A: TRV250-20mg/ml, Placebo, Part B: TRV250 Dose 1 - Migraines | Phase 1 | Terminated | Trevena Inc. | 9 | 2019-11-11 | 2021-09-22 |
| Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments 5% lidocaine/5 mg/ml 0.02% estradiol compound cream, Nortriptyline, Placebo cream - Vestibulodynia, Temporomandibular Disorder | Phase 2 | Completed | Duke University | 209 | 2019-11-04 | 2026-03-19 |
| Quantitative Sensory Testing and Occipital Nerve Stimulator occipital nerve stimulator - Migraines | Not applicable | Completed | Barts & The London NHS Trust | 6 | 2019-09-01 | 2026-03-02 |
| Pain Processing in Adults With Migraines Questionnaires, Quantitative Sensory Testing (QST) Pain Measurements - Migraines | Not applicable | Completed | Wake Forest University Health Sciences | 121 | 2016-08-24 | 2020-05-12 |
| Comparison of Ketorolac Nasal Spray to Sumatriptan Nasal Spray and Placebo for Acute Treatment of Migraine Ketorolac, Sumatriptan, Placebo - Migraines | Phase 4 | Completed | Johns Hopkins University | 72 | 2013-02-01 | 2017-03-13 |
| Integrative Coping Group for Children Integrative Coping Group - Childhood Depression, Childhood Anxiety | Not applicable | Completed | Duke University | 28 | 2012-10-01 | 2014-08-20 |
| A Nutritional Intervention for Migraines-2 Plant based diet, an unrestricted diet - Migraines | Not applicable | Completed | Physicians Committee for Responsible Medicine | 24 | 2012-10-01 | 2015-10-20 |
| Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care: - Adenovirus, Anesthesia | Completed | Daniel Benjamin | 3520 | 2011-11-01 | 2023-09-06 | |
| A Nutritional Intervention for Migraines Vegan Diet, mixture of omega3 and vitamins - Migraines | Not applicable | Completed | Physicians Committee for Responsible Medicine | 16 | 2011-09-01 | 2013-05-14 |
| A Study of LY2951742 in Healthy Volunteers LY2951742, Placebo - Migraines | Phase 1 | Completed | Eli Lilly and Company | 63 | 2011-04-01 | 2019-02-20 |
| Multiple Attacks Study to Compare the Efficacy and Safety of MK-0974 With Placebo for Acute Migraine (MK-0974-031) Telcagepant 140 mg, Talcagepant 280 mg, Placebo - Migraines | Phase 3 | Completed | Merck Sharp & Dohme LLC | 1935 | 2008-08-14 | 2018-10-18 |
| Pharmacokinetics and Safety of Intravenous Topiramate in Adult Patients intravenous topiramate - Epilepsy, Migraines | Phase 1 | Completed | University of Minnesota | 20 | 2008-08-01 | 2019-07-18 |
| Prevention of Menstrual Migraines: Using Frovatriptan or Placebo During Hormone Free Intervals frovatriptan, placebo - Migraines, Bleeding | Not applicable | Completed | Scott and White Hospital & Clinic | 30 | 2008-06-01 | 2011-07-25 |
| Genetic Analysis of Children With Cyclic Vomiting Syndrome (CVS) and Migraines Vomiting, Migraines | Completed | Medical College of Wisconsin | 586 | 2008-03-05 | 2019-12-26 | |
| A Phase III Open-Label, Multi-Center, Long-Term Extension Study of Depakote ER in Subjects Who Either Completed or Prematurely Discontinued Due to Ineffectiveness From Study M02-488. divalproex sodium - Migraines | Phase 3 | Completed | Abbott | 114 | 2004-07-01 | 2007-07-31 |
Migraine Disorders (17) · Headache (4) · Pain (3) · Anxiety Disorders (2) · Chronic Pain (2) · Endometriosis (2) · Epilepsy (2) · Fatigue Syndrome, Chronic (2) · Fibromyalgia (2) · Adenoviridae Infections (1) · Anorexia Nervosa (1) · Arrhythmias, Cardiac (1) · Arthritis, Juvenile (1) · Arthritis, Psoriatic (1) · Attention Deficit Disorder with Hyperactivity (1)
Brain Diseases (17) · Central Nervous System Diseases (17) · Headache Disorders (17) · Headache Disorders, Primary (17) · Nervous System Diseases (17) · Pathological Conditions, Signs and Symptoms (9) · Signs and Symptoms (9) · Neurologic Manifestations (7) · Female Urogenital Diseases (4) · Female Urogenital Diseases and Pregnancy Complications (4) · Genital Diseases (4) · Genital Diseases, Female (4) · Pain (4) · Pathologic Processes (4) · Urogenital Diseases (4)
Alfentanil (1) · Amikacin (1) · Aminocaproic Acid (1) · Bosentan (1) · Cefepime (1) · Cidofovir (1) · Ciprofloxacin (1) · Clozapine (1) · Diet, Plant-Based (1) · Diet, Vegan (1) · Fosfomycin (1) · Haloperidol (1) · Ketorolac (1) · Labetalol (1) · Lurasidone Hydrochloride (1)
Duke University (2) · Physicians Committee for Responsible Medicine (2) · Abbott (1) · Barts & The London NHS Trust (1) · Beth Israel Deaconess Medical Center (1) · Brain Inflammation Collaborative (1) · Daniel Benjamin (1) · Eli Lilly and Company (1) · Johns Hopkins University (1) · Medical College of Wisconsin (1) · Merck Sharp & Dohme LLC (1) · Scott and White Hospital & Clinic (1) · Trevena Inc. (1) · University of Minnesota (1) · Wake Forest University Health Sciences (1)
United States (13) · United Kingdom (3) · Belgium (1) · Canada (1) · Israel (1) · Singapore (1)
Andrea Nackley, PhD (1) · Chi Hornik, PharmD (1) · Christian Mauro, PhD (1) · James C Cloyd, PharmD (1) · Katja Kovacic, MD (1) · Megan L Fitzgerald, PhD (1) · Michael Donnino, MD (1) · Neal Barnard, MD (1) · Patricia Sulak, MD (1) · Rebecca E Wells, MD, MPH (1)
PMID 25339342, PMID 20974601, PMID 24614374, PMID 24949994, PMID 26039810, PMID 26840902, PMID 26926644, PMID 27522443, PMID 28137820, PMID 28290120, PMID 28779462, PMID 29084742, PMID 29271816, PMID 29435949, PMID 29677389, PMID 30790601, PMID 31317556, PMID 31548185, PMID 31814149, PMID 32324313, PMID 32497307, PMID 33029806, PMID 33903114, PMID 34302290, PMID 35370711, PMID 35491971, PMID 35816681, PMID 36269028, PMID 41247430, PMID 42857927
R01HD096331 (1)