Cidofovir: Clinical Trials

34 trials of Cidofovir, newest first

ClinicalTrials Daily  ·  Areas  ·  Conditions  ·  Drugs  ·  Sponsors  ·  

24 completed, 4 unknown, 3 withdrawn, 1 active not recruiting. 11 Phase 2, 8 Phase 1, 7 Not applicable, 6 Phase 3, 2 Phase 4.

By phase and status

PhaseTrialsStatus
Phase 211Completed 7, Active not recruiting 1, Terminated 1, Unknown 1, Withdrawn 1
Phase 18Completed 5, Terminated 1, Unknown 1, Withdrawn 1
Not applicable7Completed 5, Unknown 1, Withdrawn 1
Phase 36Completed 5, Recruiting 1
Phase 42Completed 2

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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
A Phase 3 Trial to Compare IV BCV Versus IV CDV for Treatment of Adenovirus Infection After Allo-HCT
cidofovir, Brincidofovir - Adenovirus Infections
Phase 3RecruitingSymBio Pharmaceuticals1802026-03-172026-10-19
Clinical Trial for Evaluating the Efficacy and Safety of Electrocoagulation vs Topic Sinecatechins vs Topic Cidofovir Within the Treatment to High-grade Anal Intraepithelial Neoplasia in HIV Homosexual Males
electrocoagulation, cidofovir 1% topical ointment, sinecatechins 10% topical ointment - High-grade Anal Intraepithelial Neoplasia
Phase 3CompletedHospital Universitari Vall d'Hebron Research Institute1082020-09-182024-07-10
Airway Intervention Registry (AIR): Recurrent Respiratory Papillomatosis (RRP)
Microdebrider, Cold-steel surgery (forceps), Carbon dioxide laser - Recurrent Respiratory Papillomatosis, Human Papilloma Virus
UnknownNewcastle-upon-Tyne Hospitals NHS Trust4002018-04-012022-01-11
Trial on Efficacy and Safety of Pritelivir Tablets for Treatment of Acyclovir-resistant Mucocutaneous HSV (Herpes Simplex Virus) Infections in Immunocompromised Subjects
Pritelivir, Investigator's choice - HSV Infection
Phase 3CompletedAiCuris Anti-infective Cures AG1582017-05-082026-06-12
Efficacy and Safety Study of Maribavir Treatment Compared to Investigator-assigned Treatment in Transplant Recipients With Cytomegalovirus (CMV) Infections That Are Refractory or Resistant to Treatment With Ganciclovir, Valganciclovir, Foscarnet, or Cidofovir
Maribavir, Ganciclovir, Valganciclovir - Cytomegalovirus (CMV)
Phase 3CompletedShire3522016-12-222021-11-03
Intralesional Cidofovir for the Treatment of Recalcitrant Warts in the Pediatric Immune-suppressed Population.
Cidofovir - Warts
Phase 2WithdrawnUniversity of Minnesota2016-06-012017-07-02
Bevacizumab Versus Cidofovir for the Treatment of Recurrent Respiratory Papillomatosis
Bevacizumab, Cidofovir, Placebo - Recurrent Respiratory Papillomatosis
Phase 2UnknownCentro de Investigación en. Enfermedades Infecciosas, Mexico362014-12-012016-07-26
A Prospective, With One Site, Open-label Not Controled Trial, for the Observation of Treatment With CIDOFOVIR 1%, 3 Nights Per Week, During 4 Weeks, of Anal Intraepithelial Neoplasia, High Level, in HIV+ Patients
Cidofovir 1% cream's basis, 2gr, three times per week, during 4 weeks. - HIV
Not applicableCompletedFundacion SEIMC-GESIDA202013-09-012016-06-29
Intravesical Cidofovir for Hemorrhagic Cystitis
Cidofovir, Probenecid - Blood And Marrow Transplantation
Phase 1CompletedM.D. Anderson Cancer Center62013-09-012016-12-06
A Prolongation of a Clinical Study to Evaluate the Efficacy of an Aqueous Gel Containing 2% (w/w) of Cidofovir, Directly Applied on the Cervix Exhibiting High Grade Squamous Intraepithelial Lesions.
Cidofovir - High Grade Cervical Epithelial Neoplasia (CIN2+)
Phase 2CompletedBrugmann University Hospital362013-02-012016-11-30
Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care
The POPS study is collecting PK data on children prescribed the following drugs of interest per standard of care: - Adenovirus, Anesthesia
CompletedDaniel Benjamin35202011-11-012023-09-06
Cidofovir Versus Best Supportive Care for Hemorrhagic Cystitis
Cidofovir, No Cidofovir - Transplantation Infection
Phase 2Active not recruitingM.D. Anderson Cancer Center272011-03-172026-09-18
Trial of Topical Cidofovir for the Prevention of Hair Growth
1% topical cidofovir, 3% topical cidofovir, Placebo - Prevention of Hair Growth
Phase 2CompletedUniversity of Pennsylvania202009-07-012012-03-19
Cidofovir in Treating Patients With Stage IB, Stage II, Stage III, or Stage IVA Cervical Cancer Who Are Receiving Chemotherapy and Radiation Therapy
carboplatin, cidofovir, protein expression analysis - Cervical Cancer, Precancerous Condition
Phase 1UnknownGustave Roussy, Cancer Campus, Grand Paris242008-04-012010-01-28
Modulation of the Expression of Papillomavirus (HPV) Oncoproteins to Major the Radiosensitivity: Trial Combining an Antiviral Agent VISTIDE and Radiochemotherapy in Cervical Cancers
External radiotherapy + curietherapy, Vistide, Carboplatin - Cervical Cancer
Phase 1CompletedGustave Roussy, Cancer Campus, Grand Paris152008-01-012026-08-13
Cidofovir in Treating HIV-Infected Patients With High-Grade Squamous Intraepithelial Lesions of the Skin Near the Anus
cidofovir, DNA methylation analysis, gene expression analysis - Anal Cancer, Precancerous Condition
Phase 2CompletedAIDS Malignancy Consortium332007-09-012015-12-21
Cidofovir in Renal Transplant Recipients With BKVN
Cidofovir, Placebo - BK Virus (Nephropathy)
Phase 1 / Phase 2TerminatedNational Institute of Allergy and Infectious Diseases (NIAID)222006-05-012013-03-08
Use of Cidofovir for Recurrent Respiratory Papillomatosis
Cidofovir, Placebo - Recurrent Respiratory Papillomatosis
Phase 4CompletedUniversity of Wisconsin, Madison191999-11-012019-02-26
Studies of Ocular Complications of AIDS (SOCA)--Ganciclovir-Cidofovir CMV Retinitis Trial (GCCRT)
Ganciclovir implant and oral ganciclovir, Cidofovir intravenous - Cytomegalovirus Retinitis, HIV Infections
Phase 3CompletedJohns Hopkins Bloomberg School of Public Health611997-05-012016-03-14
Antiviral Therapy in Treating Patients With Kaposi's Sarcoma With or Without HIV Infection
cidofovir - Sarcoma
Phase 2CompletedNational Cancer Institute (NCI)1996-11-012013-06-20

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Conditions studied

HIV Infections (12)  ·  Cytomegalovirus Retinitis (10)  ·  Acquired Immunodeficiency Syndrome (7)  ·  Cytomegalovirus Infections (4)  ·  Herpes Simplex (4)  ·  Retinitis (4)  ·  AIDS-Related Opportunistic Infections (3)  ·  Adenoviridae Infections (3)  ·  Cystitis, Hemorrhagic (3)  ·  Recurrent respiratory papillomatosis (3)  ·  Cystitis (2)  ·  Pain (2)  ·  Precancerous Conditions (2)  ·  Squamous Intraepithelial Lesions (2)  ·  Uterine Cervical Neoplasms (2)

Sponsors

Gilead Sciences (6)  ·  National Institute of Allergy and Infectious Diseases (NIAID) (6)  ·  M.D. Anderson Cancer Center (3)  ·  Gustave Roussy, Cancer Campus, Grand Paris (2)  ·  Johns Hopkins Bloomberg School of Public Health (2)  ·  AIDS Malignancy Consortium (1)  ·  AiCuris Anti-infective Cures AG (1)  ·  Brugmann University Hospital (1)  ·  Centro de Investigación en. Enfermedades Infecciosas, Mexico (1)  ·  Daniel Benjamin (1)  ·  Fundacion SEIMC-GESIDA (1)  ·  Hospital Universitari Vall d'Hebron Research Institute (1)  ·  National Cancer Institute (NCI) (1)  ·  National Center for Research Resources (NCRR) (1)  ·  Newcastle-upon-Tyne Hospitals NHS Trust (1)

Countries

United States (21)  ·  United Kingdom (6)  ·  Canada (5)  ·  France (5)  ·  Belgium (4)  ·  Spain (4)  ·  Germany (3)  ·  Italy (3)  ·  Australia (2)  ·  Austria (2)  ·  Denmark (2)  ·  Israel (2)  ·  Mexico (2)  ·  Singapore (2)  ·  Switzerland (2)

Top investigators

Douglas Jabs, MD (2)  ·  Roy F. Chemaly, MD, MPH, MBA (2)  ·  Adam Donne (1)  ·  Barker DE (1)  ·  Borje S. Andersson, MD,PHD (1)  ·  Catherine Vanpachterbeke, MD (1)  ·  Chi Hornik, PharmD (1)  ·  Dankner W (1)  ·  David V. Weinberg (1)  ·  Elena Sendagorta, MD (1)  ·  Elizabeth Stier, MD (1)  ·  Eric Deutsch, MD (1)  ·  Ingrid Polcari, MD (1)  ·  J. Scott McMurray, MD (1)

Results publications

PMID 18700421, PMID 21692673, PMID 23032420, PMID 24614374, PMID 24949994, PMID 26039810, PMID 26612873, PMID 26731755, PMID 26926644, PMID 27016411, PMID 27522443, PMID 28137820, PMID 28290120, PMID 28779462, PMID 29084742, PMID 29271816, PMID 29435949, PMID 29677389, PMID 30790601, PMID 31042791, PMID 31317556, PMID 31548185, PMID 31814149, PMID 32324313, PMID 32497307, PMID 33029806, PMID 33811823, PMID 33903114, PMID 34302290, PMID 34864943, PMID 35370711, PMID 35397828, PMID 35491971, PMID 37506264, PMID 38071422, PMID 39445512, PMID 39613120, PMID 40036375, PMID 40478680, PMID 41247430, PMID 41384277

NIH funding

2015 (1), U01CA121947 (1)