26 completed, 9 unknown, 7 recruiting, 3 terminated. 12 Phase 4, 11 Not applicable, 9 Phase 2, 4 Early Phase 1, 3 Phase 1.
Follow Amikacin: new trials by email Literature Review of Amikacin trials Research Report on Amikacin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Testing a Novel Combination Treatment (Arm D) Versus Standard of Care for Intensive Phase Treatment for Mycobacterium Abscessus Pulmonary Disease in People With or Without Cystic Fibrosis in the Finding the Optimal Regimen for Mycobacterium Abscessus Treatment (FORMaT) Adaptive Platform Trial Sulbactam 25mg/kg -Durlobactam 25mg/kg (Every 6 hours), Ceftriaxone for Injection, Amoxicillin - Mycobacterium Abscessus Pulmonary Disease, Mycobacterium Abscessus Infection | Phase 2 | Not yet recruiting | The University of Queensland | 300 | 2027-04-01 | 2026-03-20 |
| " Study of the Benefit of Nebulized Amikacin in the Treatment of Gram-negative Bacillus Pneumonia Acquired During Mechanical Ventilation in Patients Receiving Extracorporeal Membrane Veno-arterial Oxygenation " Amikacin, Standard of care - Pneumonia, Bacterial, Extracorporeal Membrane Oxygenation | Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 26 | 2026-08-10 | 2026-08-13 |
| Early Discontinuation of Antibiotics in Paediatric High-risk Febrile Neutropenia Early Discontinuation of Antibiotics, Standard Antibiotic Continuation Strategy - Febrile Neutropenia (FN), Pediatric Cancer | Phase 4 | Not yet recruiting | Hospital Universitari Vall d'Hebron Research Institute | 136 | 2026-06-01 | 2026-05-15 |
| Bacteriophage Therapy for Mycobacterium Abscessus Pulmonary Infection Mycobacteriophage Muddy_HRMN0052, Amikacin Injection, Clofazimine - Non-Tuberculous Mycobacterial (NTM) Pneumonia, Mycobacterium Abscessus Infection | Phase 1 | Enrolling by invitation | Vancouver Coastal Health | 1 | 2026-01-11 | 2026-06-03 |
| Colistin and Meropenem Versus Amikacin and Meropenem for MDR Gram Negative Bacteria Regarding Efficacy and Safety. Colistimethate sodium for injection, meropenem, Amikacin Injection and meropenem - MDR Bacteria | Phase 4 | Active not recruiting | Beni-Suef University | 100 | 2025-12-30 | 2026-07-14 |
| Potentiated Aminoglycosides in Postoperative Urinary Tract Infection Prophylaxis mannitol-enhanced aminoglycoside, Ceftriaxon, Amikacin - Urinary Tract Infections, Urological System Complication of Procedure | Early Phase 1 | Unknown | Centre Hospitalier Universitaire Vaudois | 90 | 2024-01-16 | 2024-02-08 |
| Clinical Outcomes of Inhaled Amikacin in Ventilator Associated Pneumonia Amikacin (Inhalation), Standard-of-Care Intravenous Antibiotics - Ventilator Associated Pneumonia ( VAP) | Phase 4 | Completed | Postgraduate Medical Institute, Lahore | 90 | 2024-01-05 | 2026-01-27 |
| the Incidence of Necrotizing Enterocolitis in Preterm With Respiratory Distress Syndrome Undergoing Caffeine Therapy Caffeine citrate, Amikacin - Pharmacological Action of Drug | Early Phase 1 | Unknown | Al-Azhar University | 50 | 2023-10-19 | 2023-10-24 |
| Preventing Acquired Resistance: Strengthen TB Treatment by Adding Amikacin in the First Treatment Week of Multidrug-resistant Tuberculosis Amikacin - Tuberculosis, Multidrug-Resistant | Phase 2 | Unknown | Rwanda Biomedical Centre | 20 | 2023-03-01 | 2023-03-29 |
| Single Dose Amikacin for Uncomplicated Cystitis in the ED: A Feasibility Study Amikacin - Urinary Tract Infections | Recruiting | Antonios Likourezos | 75 | 2022-09-21 | 2026-09-11 | |
| Patient Satisfaction and Long-term Safety of Intravesical Aminoglycoside Instillations in UTI Prevention Intravesical aminoglycoside instillations - Urinary Tract Infections, Recurrent Urinary Tract Infection | Completed | Leiden University Medical Center | 44 | 2022-04-20 | 2023-03-08 | |
| Early Versus Late Stopping of Antibiotics in Children With Cancer and High-risk Febrile Neutropenia Piperacillin and Tazobactam for Injection, Cefepime Injection, Ceftazidime Injection - Febrile Neutropenia | Phase 4 | Completed | Murdoch Childrens Research Institute | 55 | 2021-11-15 | 2026-03-20 |
| Management of Ventilation Acquired Pneumonia Caused by Pseudomonas and Acinetobacter Organisms in a Pediatric Center extended meropenem infusion in combination with other options such as Polymyxin, Tigecycline, Ertapenem, or Amikacin., two β-lactam antibiotics plus a single non-β-lactam antibiotic, Control group received standard therapy - Ventilation Acquired Pneumonia | Phase 3 | Completed | Beni-Suef University | 64 | 2021-01-01 | 2024-12-18 |
| Pharmacokinetics of Amikacin and Cefuroxime in Critically Ill Patients. Cefuroxime, Amikacin - Sepsis, Septic Shock | Unknown | Radboud University Medical Center | 40 | 2020-07-15 | 2022-09-10 | |
| Finding the Optimal Regimen for Mycobacterium Abscessus Treatment Amikacin, Tigecycline, Imipenem - Pulmonary Disease Due to Mycobacteria (Diagnosis) | Phase 2 / Phase 3 | Recruiting | The University of Queensland | 300 | 2020-03-02 | 2026-05-11 |
| Amikacin Pharmacokinetic Profile in Plasma and Tissue After an Administration Using Impregnated Dressings in Burned Patient Population Treatment with Amikacin - Burn Patients | Phase 4 | Terminated | Assistance Publique Hopitaux De Marseille | 7 | 2020-01-06 | 2024-07-01 |
| Antimicrobial Prophylaxis in Patients Who Underwent a Transurethral Resection of Bladder (TURB) Fosfomycin Tromethamine 3G Sachet, Amikacin - Urinary Tract Infections, Bladder Cancer | Phase 2 | Completed | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | 75 | 2020-01-01 | 2023-04-04 |
| Population Pharmacokinetics of Amikacin in Neonates Amikacin Sulfate Injection - Neonatal Sepsis, Late-Onset | Completed | Pontificia Universidad Catolica de Chile | 138 | 2019-12-01 | 2022-04-07 | |
| Fixed-dose Amikacin for Elderly UTI Amikacin - Urinary Tract Infections, Elderly Infection | Phase 4 | Unknown | Rabin Medical Center | 200 | 2019-12-01 | 2019-12-13 |
| Optimized Antibiotic Therapy in Patients With Subarachnoid Haemorrhage (ES) and Cerebral Haemorrhage (EC) Piperacillin/tazobactam, Meropenem, Daptomycin - Therapeutic Drug Monitoring, Subarachnoid Hemorrhage | Unknown | Azienda Sanitaria-Universitaria Integrata di Udine | 104 | 2019-10-01 | 2021-07-21 |
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Urinary Tract Infections (7) · Infections (5) · Pneumonia, Ventilator-Associated (5) · Pneumonia (4) · Sepsis (4) · Febrile Neutropenia (3) · HIV Infections (3) · Lung Diseases (3) · Mycobacterium Infections, Nontuberculous (3) · Neoplasms (3) · Neutropenia (3) · Acquired Immunodeficiency Syndrome (2) · Bacterial Infections (2) · Cystic Fibrosis (2) · Healthcare-Associated Pneumonia (2)
National Institute of Allergy and Infectious Diseases (NIAID) (3) · Assistance Publique - Hôpitaux de Paris (2) · Beni-Suef University (2) · The University of Queensland (2) · Al-Azhar University (1) · Antonios Likourezos (1) · Assistance Publique Hopitaux De Marseille (1) · Azienda Sanitaria-Universitaria Integrata di Udine (1) · Bayer (1) · Beijing Children's Hospital (1) · Cardeas Pharma (1) · Centre Hospitalier Intercommunal Creteil (1) · Centre Hospitalier Universitaire Vaudois (1) · Centre Hospitalier Universitaire de Nīmes (1) · Cliniques universitaires Saint-Luc- Université Catholique de Louvain (1)
United States (10) · France (8) · Egypt (3) · Netherlands (3) · United Kingdom (3) · Argentina (2) · Australia (2) · Belgium (2) · Canada (2) · China (2) · India (2) · Israel (2) · Singapore (2) · Spain (2) · Thailand (2)
A-Dong Shen, Master (1) · Annick de Jaeger, MD (1) · Anthony J Schaeffer, MD (1) · Benson C (1) · Chee Fui Chong, FRCSEd (1) · Chi Hornik, PharmD (1) · Chirgwin K (1) · DM Parenti (1) · David Seligson, MD (1) · Florian Thalhammer, Prof. Dr. (1) · Gabrielle Haeusler (1) · J Ellner (1)
PMID 15276398, PMID 15840453, PMID 16470119, PMID 16988514, PMID 18366444, PMID 18570578, PMID 18752007, PMID 18795962, PMID 18989231, PMID 19588358, PMID 19698010, PMID 20002783, PMID 20632458, PMID 21283017, PMID 22083071, PMID 22129166, PMID 22147112, PMID 22530208, PMID 23305215, PMID 23392467, PMID 24614374, PMID 24903189, PMID 24949994, PMID 25084971, PMID 25162818, PMID 25261418, PMID 25327505, PMID 25407158, PMID 25950206, PMID 25959631, PMID 26039810, PMID 26202768, PMID 26429564, PMID 26918544, PMID 26926644, PMID 27522443, PMID 27540363, PMID 28137820, PMID 28290120, PMID 28592230, PMID 28779462, PMID 29084742, PMID 29180278, PMID 29271816, PMID 29369162, PMID 29435949, PMID 29520730, PMID 29528944, PMID 29677389, PMID 30134297
2015 (1)