10 unknown, 9 completed, 1 active not recruiting, 1 recruiting. 23 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 23 | Unknown 10, Completed 9, Active not recruiting 1, Recruiting 1, Terminated 1, Withdrawn 1 |
Follow Mechanical Ventilation: new trials by email Literature Review of Mechanical Ventilation trials Research Report on Mechanical Ventilation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Shorter Weaning From Invasive Ventilation With Levosimendan levosimendan, Soluvit, Standard care - Mechanical Ventilation, Weaning Failure | Phase 4 | Recruiting | Radboud University Medical Center | 250 | 2025-09-17 | 2026-01-09 |
| Clinical Study of Esketamine in Patients With Sepsis Undergoing Invasive Mechanical Ventilation Esketamine, Remifentanil - Sepsis, Mechanical Ventilation | Phase 4 | Active not recruiting | Second Affiliated Hospital of Nanchang University | 80 | 2025-01-01 | 2026-04-29 |
| Sedation in ICU Patients With Mechanical Ventilation Ciprofol, Sedation with Propofol - Sedation, Mechanical Ventilation | Phase 4 | Completed | Zhongda Hospital | 366 | 2024-08-01 | 2026-06-30 |
| Efficacy and Safety of Oxycodone Hydrochloride for Long-term Analgesia in ICU Patients Oxycodone Hydrochloride, Remifentanil - Oxycodone, Analgesia | Phase 4 | Unknown | Shanghai Zhongshan Hospital | 60 | 2024-06-01 | 2024-06-06 |
| Night-time Dexmedetomidine-esketamine Infusion and Sleep Quality in ICU Patients Dexmedetomidine-esketamine, Routine sedation and analgesia - Intensive Care Unit, Mechanical Ventilation | Phase 4 | Completed | Peking University First Hospital | 174 | 2023-11-01 | 2025-12-05 |
| Ketamine Versus Propofol as ICU Sedation Ketamine, Propofol - Ketamine, Propofol | Phase 4 | Completed | Menoufia University | 100 | 2022-10-01 | 2024-02-06 |
| Safety and Efficacy of Esketamine Combined With Dexmedetomidine for Sedation of Mechanically Ventilated Patients Esketamine combined with dexmedetomidine, Dexmedetomidine - Dexmedetomidine, Ketamine | Phase 4 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 100 | 2022-08-11 | 2024-05-07 |
| Pharmacokinetic Study of Continuous Infusion of Remazolam in Mechanically Ventilated Patients in ICU Remimazolam 0.1mg/kg/h, Remimazolam 0.3mg/kg/h, Remimazolam 0.5mg/kg/h - Intensive Care Unit, Mechanical Ventilation | Phase 4 | Unknown | The First Affiliated Hospital with Nanjing Medical University | 30 | 2022-02-01 | 2022-07-29 |
| Cardiac Output Response to Vasopressin Infusion In Abdominal Surgery Patients Under Mechanical Ventilation Vasopressin, Arginine - Major Abdominal Surgery, General Anesthesia | Phase 4 | Completed | University Hospital, Clermont-Ferrand | 20 | 2021-06-09 | 2022-12-05 |
| Compare the Effects of Remifentanil and Fentanyl on the Duration of Mechanical Ventilation of ICU Patients Remifentanil, Fentanyl - Mechanical Ventilation | Phase 4 | Unknown | Capital Medical University | 254 | 2020-01-01 | 2021-08-20 |
| Transcutaneous Diaphragm Electrical Stimulation in Critically Ill Patients Sham electrical stimulation, Transcutaneous diaphragm electrical stimulation - Critical Illness, Mechanical Ventilation | Phase 4 | Completed | Groupe Hospitalier du Havre | 66 | 2019-12-10 | 2022-08-04 |
| Prednisone Reduction in ICU Patients With COPD Exacerbation Prednisone - Copd Exacerbation Acute, Mechanical Ventilation | Phase 4 | Unknown | Hôpital Universitaire Fattouma Bourguiba | 192 | 2019-04-02 | 2019-06-10 |
| Dexmedetomidine vs Midazolam on Resting Energy Expenditure in Critically Ill Patients Dexmedetomidine, Midazolam, Fentanyl - Mechanical Ventilation, Dexmedetomidine | Phase 4 | Completed | Cairo University | 30 | 2017-01-01 | 2018-03-27 |
| Midazolam Used Alone or Sequential Use of Midazolam and Propofol/Dexmedetomidine in Mechanically Ventilated Patients midazolam, Fentanyl, propofol - Mechanical Ventilation, Complication | Phase 4 | Unknown | West China Hospital | 240 | 2015-12-01 | 2016-04-28 |
| Early Goal-Directed Nutrition in ICU Patients - EAT-ICU Trial Early Goal-Directed Nutrition, ASPEN-guidelines - Critical Illness, Intensive Care (ICU) Myopathy | Phase 4 | Completed | Copenhagen University Hospital, Rigshospitalet | 203 | 2013-06-01 | 2017-01-05 |
| FRC Guided Therapy in Acute Respiratory Failure alveolar recruitment manoeuvre - Mechanical Ventilation, Acute Respiratory Failure | Phase 4 | Unknown | University of Luebeck | 20 | 2010-10-01 | 2011-01-20 |
| Proportional Assist Ventilation (PAV) in Early Stage of Critically Ill Patients Mechanical ventilation mode (PAV+ vs. ACV) - Respiratory Failure, Mechanical Ventilation | Phase 4 | Completed | Althaia Xarxa Assistencial Universitària de Manresa | 110 | 2010-09-01 | 2012-11-27 |
| Effect of Daily Nicotine Patch Application on Mechanical Ventilation Weaning in Smoking Patients Nicotine patch, Placebo - Smoking, Mechanical Ventilation | Phase 4 | Unknown | University of Paris 5 - Rene Descartes | 600 | 2010-01-01 | 2010-04-16 |
| Dexmedetomidine Versus Propofol in the Medical Intensive Care Unit (MICU) Dexmedetomidine, Propofol, Fentanyl - Mechanical Ventilation, Critical Illness | Phase 4 | Terminated | University of Chicago | 41 | 2009-09-01 | 2018-07-03 |
| Cpap at Delivery Room for Preterm Infants CPAP - Mechanical Ventilation, Retinal Disease | Phase 4 | Unknown | University of Sao Paulo | 200 | 2009-01-01 | 2009-12-23 |
Showing 20 of 23. Sign in to see all of them.
Agnosia (3) · Critical Illness (3) · Respiratory Aspiration (2) · Respiratory Insufficiency (2) · Death (1) · Delirium (1) · Diabetes Insipidus (1) · Liver Failure (1) · Muscular Atrophy (1) · Muscular Diseases (1) · Pneumonia, Ventilator-Associated (1) · Pulmonary Disease, Chronic Obstructive (1) · Respiratory Tract Diseases (1) · Retinal Diseases (1) · Sepsis (1)
Pathological Conditions, Signs and Symptoms (12) · Pathologic Processes (8) · Nervous System Diseases (6) · Disease Attributes (5) · Neurologic Manifestations (5) · Respiratory Tract Diseases (5) · Signs and Symptoms (5) · Neurobehavioral Manifestations (4) · Respiration Disorders (4) · Perceptual Disorders (3) · Infections (2) · Lung Diseases (2) · Mental Disorders (2) · Atrophy (1) · Behavior (1)
Dexmedetomidine (4) · Fentanyl (4) · Propofol (4) · Midazolam (3) · Remifentanil (3) · (2-(1R)-1-cyclopropyl)ethyl-6-isopropyl-phenol (1) · Analgesia (1) · Arginine Vasopressin (1) · Calorimetry (1) · Calorimetry, Indirect (1) · Esketamine (1) · Interactive Ventilatory Support (1) · Ketamine (1) · Nicotine Chewing Gum (1) · Norepinephrine (1)
The First Affiliated Hospital with Nanjing Medical University (2) · Althaia Xarxa Assistencial Universitària de Manresa (1) · Cairo University (1) · Capital Medical University (1) · Copenhagen University Hospital, Rigshospitalet (1) · Groupe Hospitalier du Havre (1) · Hospital Universitario de Canarias (1) · Hôpital Universitaire Fattouma Bourguiba (1) · Menoufia University (1) · Peking University First Hospital (1) · Radboud University Medical Center (1) · Second Affiliated Hospital of Nanchang University (1) · Shanghai Zhongshan Hospital (1) · Unidade de Terapia Intensiva (1) · University Hospital, Clermont-Ferrand (1)
China (8) · France (3) · Egypt (2) · United States (2) · Brazil (1) · Denmark (1) · Germany (1) · Morocco (1) · Netherlands (1) · Spain (1) · Tunisia (1)
Anders Perner, Professor, MD, PhD (1) · Didier Journois, M.D. Ph.D. (1) · Dong-Xin Wang, MD, PhD (1) · Francisco E Martinez, MD (1) · Jian-Xin Zhou, MD (1) · John P Kress, MD (1) · Leonardo Lorente, MD, PhD (1) · Matilde Jo Allingstrup, PhD Fellow, MSc (1) · Ming Zhong (1) · Mohamed Abdulatif, Professor (1) · Mostafa Saieed Mansour, MD (1) · Rafael Fernandez, M.D. (1) · Thomas Godet (1) · Y Kang, Dr (1) · Zuo Xiangrong (1)
PMID 10712328, PMID 16394778, PMID 17872488, PMID 25004265, PMID 27585532, PMID 28936712, PMID 35505432, PMID 37649092, PMID 38956664, PMID 40517312, PMID 42161542