88 completed. 88 Not applicable.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 88 | Completed 88 |
Follow Mechanical Ventilation: new trials by email Literature Review of Mechanical Ventilation trials Research Report on Mechanical Ventilation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Periodic Recruitment Maneuvers on Atelectasis and Respiratory Mechanics During Elective Spine Surgery Assessed by Lung Ultrasonography Alveolar Recruitment Maneuver - Atelectasis, Mechanical Ventilation | Not applicable | Completed | Prof. Dr. Cemil Tascıoglu Education and Research Hospital Organization | 60 | 2026-04-11 | 2026-10-29 |
| Turkish Validity and Reliability of the Behavioral Indicators of Pain Scale(ESCID) The ESCID scale - Mechanical Ventilation, Pain Perception | Not applicable | Completed | Saglik Bilimleri Universitesi | 55 | 2026-03-01 | 2026-10-21 |
| Circadian Feeding and Reciprocal Scent Intervention in NICU Reciprocal Scent Intervention, Circadian-Aligned Feeding, Standard Care (in control arm) - Prematurity, Mechanical Ventilation | Not applicable | Completed | Inonu University | 150 | 2025-10-01 | 2026-06-03 |
| eCASH and Early Goal-Directed Mobilization to Prevent ICU-Acquired Weakness eCASH-Based Analgesia and Sedation Strategy Combined With Early Goal-Directed Mobilization, Routine ICU Nursing Care - ICU-acquired Weakness, Mechanical Ventilation | Not applicable | Completed | The First Affiliated Hospital of Soochow University | 70 | 2025-10-01 | 2026-06-30 |
| Clinical Application of the Effect of Respiratory Muscles Electrical Stimulation on Weaning in Patients With Difficult Weaning of the Mechanical Ventilation TEDS (Transcutaneous Diaphragmatic/Phrenic Nerve Stimulation), abFES (Functional Electrical Stimulation of Abdominal Muscles), Sham TEDS - Mechanical Ventilation | Not applicable | Completed | Capital Medical University | 300 | 2025-09-29 | 2026-08-11 |
| Hyperoxia vs Normoxia During Cardiopulmonary Bypass Hyperoxia group, Normoxia group (control) - AKI, Renal Replacement Therapy | Not applicable | Completed | University of Padova | 104 | 2025-07-01 | 2026-04-03 |
| Use of Endotracheal Tube Cuff Pressure to Assess Inspiratory Effort During Pressure Support Ventilation Pressure support 15, Pressure support 13, Pressure support 11 - Mechanical Ventilation, Critical Care | Not applicable | Completed | Jian-Xin Zhou | 30 | 2025-05-20 | 2026-01-21 |
| Comparison of Automatic and Manual Endotracheal Tube Cuff Pressure Monitoring in Pediatric Intensive Care Patients Automatic Cuff Pressure Control - Cuff Pressure, Mechanical Ventilation | Not applicable | Completed | Dr. Behcet Uz Children's Hospital | 32 | 2025-05-02 | 2025-11-25 |
| Comparison of Standard Versus Dynamic Compliance-Guided Individualized PEEP in Obese Patients Undergoing Spinal Surgery Standard PEEP - Obesity, Postoperative Pulmonary Complications | Not applicable | Completed | Konya City Hospital | 80 | 2025-02-02 | 2026-02-05 |
| Using Continuous Passive Motion to Prevent Ankle Problems in ICU Patients Continuous Passive Motion (CPM) - Joint Contracture, Mechanical Ventilation | Not applicable | Completed | Shin Kong Wu Ho-Su Memorial Hospital | 12 | 2024-11-20 | 2025-04-25 |
| Early Switch From Controlled to Assisted Ventilation Pre-specified switch from controlled to assisted ventilation when PaO2/FiO2-ratio > 200 mmHg - Acute Hypoxemic Respiratory Failure, Mechanical Ventilation | Not applicable | Completed | Erasmus Medical Center | 20 | 2024-09-15 | 2026-09-16 |
| Controlled Ventilation During Anesthetic Emergence Controlled/Full-Support Mechanical Ventilation During Emergence - Emergence From Anesthesia, Mechanical Ventilation | Not applicable | Completed | King Abdulaziz Medical City | 76 | 2024-08-17 | 2026-10-07 |
| Sigh in Pressure Support Ventilation to Detect Respiratory System Compliance and Lung Recruitability PSV + sigh (Clinical PEEP and Clinical PEEP + 3 cmH₂O) - Mechanical Ventilation | Not applicable | Completed | AUSL Romagna Rimini | 110 | 2024-07-30 | 2025-09-15 |
| The Effects of Positive End-expiratory Pressure (PEEP) on Optic Nerve Sheath Diameter in Laparoscopic Cholecystectomy Positive End-Expiratory Pressure (PEEP) - Positive End-expiratory Pressure (PEEP), Intracranial Pressure | Not applicable | Completed | Nigde Omer Halisdemir University | 34 | 2024-05-23 | 2026-06-02 |
| Pacing In Organ Donors (the POD Trial) Lungpacer AeroPace catheter and device - Lung, Organ Donation | Not applicable | Completed | Fraser Health | 3 | 2024-01-31 | 2026-04-08 |
| Comparison of Green Tea, White Tea, and Chlorhexidine Oral Care for Prevention of Ventilator-Associated Pneumonia Clorhexidine group, Green Tea group, white tea group - Ventilation Acquired Pneumonia, Mechanical Ventilation | Not applicable | Completed | Recep Tayyip Erdogan University | 63 | 2024-01-01 | 2026-07-08 |
| AMBU Bag Manual Ventilation vs. Transport Ventilator Mechanical Ventilation for Transport Hamilton C1 ventilator during transport to the ICU - Oxygenation, Manual Ventilation | Not applicable | Completed | Thomas Jefferson University | 78 | 2023-11-01 | 2026-02-03 |
| Comparison of the Effects of Inspiratory Muscle Training Methods in Mechanically Ventilated Patients Mechanical Ventilation Device, External Device - Mechanical Ventilation, Intensive Care Units | Not applicable | Completed | Saglik Bilimleri Universitesi | 38 | 2023-11-01 | 2025-01-23 |
| Dexmedetomidine and Propofol in Mechanically Ventilated Patients by Using Salivary Alpha-amylase as a Stress Marker Dexmedetomidine, Propofol - Dexmedetomidine, Propofol | Not applicable | Completed | Tanta University | 40 | 2023-10-24 | 2024-05-14 |
| Solid State vs. Balloon Esophageal Catheter for Estimation of Pleural Pressure intelligent Esophageal Pressure Catheter (iEPC) - Respiratory Failure, Mechanical Ventilation | Not applicable | Completed | Erasmus Medical Center | 16 | 2023-10-20 | 2024-05-02 |
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Respiratory Insufficiency (10) · Critical Illness (8) · COVID-19 (3) · Pulmonary Atelectasis (3) · Respiratory Distress Syndrome (3) · Agnosia (2) · Edema (2) · Pain (2) · Pneumonia, Ventilator-Associated (2) · Acute Lung Injury (1) · Arrhythmias, Cardiac (1) · Cardiac Output, Low (1) · Cardiomyopathies (1) · Coronavirus Infections (1) · Cough (1)
Respiratory Tract Diseases (24) · Pathological Conditions, Signs and Symptoms (21) · Pathologic Processes (15) · Respiration Disorders (15) · Lung Diseases (12) · Signs and Symptoms (12) · Disease Attributes (11) · Nervous System Diseases (7) · Neurologic Manifestations (7) · Infections (6) · Neurobehavioral Manifestations (5) · Respiratory Tract Infections (5) · Cardiovascular Diseases (4) · Heart Diseases (4) · Pneumonia (4)
Dexmedetomidine (2) · Standard of Care (2) · Acupressure (1) · Anesthetics, Local (1) · Continuous Positive Airway Pressure (1) · Diagnostic Imaging (1) · Ear Protective Devices (1) · Early Ambulation (1) · Educational Status (1) · External Fixators (1) · Fentanyl (1) · Ischemic Preconditioning (1) · Lidocaine (1) · Motion Therapy, Continuous Passive (1) · Positive-Pressure Respiration (1)
University Hospital, Clermont-Ferrand (4) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (2) · Assistance Publique - Hôpitaux de Paris (2) · Brazilian Institute of Higher Education of Censa (2) · Centre Hospitalier Régional d'Orléans (2) · Erasmus Medical Center (2) · Hospital Clinic of Barcelona (2) · Jian-Xin Zhou (2) · McMaster University (2) · Saglik Bilimleri Universitesi (2) · St. Justine's Hospital (2) · Tanta University (2) · University Hospital, Caen (2) · AUSL Romagna Rimini (1) · Affiliated Hospital of Jiangnan University (1)
France (15) · Turkey (Türkiye) (12) · China (7) · Taiwan (7) · Brazil (6) · Egypt (6) · Netherlands (6) · United States (6) · Canada (5) · Spain (4) · Austria (2) · Italy (2) · Australia (1) · Chile (1) · Croatia (1)
Annemijn Jonkman, PhD (2) · Amal R Ali, MD (1) · Annop Piriyapatsom, MD (1) · Ashutosh N Aggarwal, MD, DM, FCCP (1) · Brian Fuller, MD (1) · Cornelia WE Hoedemaekers, MD PhD (1) · David Orlikowski, MD-PhD (1) · Emmanuel Futier (1) · Esra Pehlivan, Ass.Prof. (1) · Esra Pehlivan, Prof Dr (1) · Ferid Aliyev, MD (1)
PMID 25425705, PMID 26471790, PMID 26515515, PMID 26938617, PMID 28030555, PMID 29336938, PMID 29404723, PMID 31272379, PMID 31618346, PMID 32376293, PMID 33306936, PMID 33328261, PMID 33688090, PMID 33980526, PMID 35523498, PMID 35866657, PMID 36958363, PMID 36964614, PMID 38528475, PMID 38631841, PMID 38737762, PMID 38865147, PMID 39078857, PMID 39871347, PMID 40642177, PMID 40839096, PMID 41035043, PMID 41364152, PMID 41708744, PMID 41841304, PMID 41912661, PMID 41928031, PMID 42175764, PMID 42461207, PMID 42611407
R34HL150404 (1)