180 completed, 56 unknown, 28 recruiting, 19 terminated. 145 Not applicable, 34 Phase 2, 28 Phase 4, 25 Phase 3, 24 Phase 1.
Follow Intermittent Claudication: new trials by email Literature Review of Intermittent Claudication trials Research Report on Intermittent Claudication
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| FGF-1 for Intramuscular Injection for the Treatment of Peripheral Arterial Disease FGF-1, Placebo - Peripheral Arterial Disease, Stenosis | Phase 1 / Phase 2 | Not yet recruiting | Venturis Therapeutics, Inc. | 24 | 2028-10-15 | 2026-08-19 |
| The NICE-PAD II Trial Nicotinamide Riboside (NR), Placebo - Peripheral Artery Disease (PAD) | Phase 3 | Not yet recruiting | Northwestern University | 250 | 2026-12-01 | 2026-08-24 |
| Evaluation of the Effectiveness of Hybrid Cardiac Rehabilitation in Peripheral Artery Disease Hybrid Cardiac Rehabilitation, Supervised Exercise Therapy - Peripheral Arterial Disease | Not applicable | Not yet recruiting | Biruni University | 40 | 2026-09-16 | 2026-04-24 |
| Predictors of Major Adverse Limb Events After Endovascular Iliac Stenting: a Real-world Cohort Study Iliac stenting - Peripheral Arterial Disease, Aortoiliac Occlusive Disease | Recruiting | I.R.C.C.S Ospedale Galeazzi-Sant'Ambrogio | 98 | 2026-06-16 | 2026-06-30 | |
| Expression of GLP1 Receptor on Peripheral Blood Mononuclear Cells in Advanced Peripheral Artery Disease: Paving the Way for GLP1R Agonists Treatment in Chronic Limb Threatening Ischemia Analysis of GLP-1 receptor expression - Peripheral Arterial Disease (PAD), Claudication, Intermittent | Not yet recruiting | University Hospital, Strasbourg, France | 50 | 2026-06-01 | 2026-01-14 | |
| CT Body Composition as Predictor of Exercise Therapy Outcome in Peripheral Arterial Disease SET physiotherapy, CT scan - Sarcopenia, Body Composition | Not yet recruiting | Nemocnice AGEL Trinec-Podlesi a.s. | 128 | 2026-06-01 | 2026-02-25 | |
| Recreational Team Handball Programme for Patients With Peripheral Arterial Disease Recreational team handball programme - Peripheral Arterial Disease (PAD) | Not applicable | Not yet recruiting | University Institute of Maia | 60 | 2026-05-14 | 2026-05-13 |
| EVERO Drug-coated Balloon (DCB) Randomized Trial Evero DCB, Paclitaxel DCB - Peripheral Vascular Disease, Peripheral Arterial Disease | Not applicable | Recruiting | Cook Research Incorporated | 410 | 2026-04-17 | 2026-10-13 |
| Evaluation of Safety, Tolerability and Preliminary Efficacy of Etrinabdione in Patients With Peripheral Arterial Disease Etribnabdione 25 mg BID, Etribnabdione 50 mg BID - Peripheral Arterial Disease | Phase 2 | Not yet recruiting | VivaCell Biotechnology España | 30 | 2026-01-01 | 2025-09-17 |
| Presence of Dural Pulsation in Patients Diagnosed With Lumbar Spinal Stenosis Lumbar Spinal Stenosis, Numerical Rating Scale | Recruiting | Marmara University | 100 | 2025-12-07 | 2026-03-11 | |
| Acute Effects of Exercise in Peripheral Arterial Disease Patients Aerobic exercise, Traditional strength exercise, Circuit strength exercise - Aerobic Physical Exercise, Traditional Strength Exercise | Not applicable | Not yet recruiting | European University Miguel de Cervantes | 16 | 2025-12-01 | 2025-12-01 |
| Observing the Role of Inflammation in Peripheral Artery Disease and Its Impact on Heart and Mobility Health: PANACEA-O. Peripheral Vascular Disease | Recruiting | Cardiology Research UBC | 50 | 2025-09-25 | 2026-03-30 | |
| Improving Mobility After Revascularization in Peripheral Artery Disease Home Based Exercise, Nitrate Rich Beetroot Juice, Attention Control - Peripheral Artery Disease, Intermittent Claudication | Phase 3 | Recruiting | Northwestern University | 386 | 2025-08-04 | 2026-10-05 |
| Personalised Multicomponent Exercise Programme in Peripheral Arterial Disease Exercise, Usual care - Peripheral Arterial Disease, Intermittent Claudication | Not applicable | Recruiting | University of Trás-os-Montes and Alto Douro | 40 | 2025-06-20 | 2025-06-27 |
| Heat Therapy and Peripheral Artery Disease Heat Therapy Intervention - Peripheral Arterial Disease, Cardiovascular Health | Not applicable | Not yet recruiting | Manchester Metropolitan University | 70 | 2025-05-01 | 2025-02-14 |
| Local or Systemic Effects: Mechanisms Related to Arm Crank Exercise - Comparison Between Individuals With and Without PAD Exercise - Peripheral Arterial Disease | Not applicable | Enrolling by invitation | University of Nove de Julho | 24 | 2025-03-24 | 2026-04-13 |
| Response to Exercise and Nitric Oxide in PAD Supervised Treadmill Exercise, Attention Control, Nitrate-Rich Beetroot Juice + supervised exercise therapy - Peripheral Artery Disease, Exercise | Phase 2 | Recruiting | Northwestern University | 200 | 2025-01-23 | 2026-07-27 |
| Heat Therapy for Peripheral Arterial Disease (HEATPAD) AirGlove - Peripheral Arterial Disease, Intermittent Claudication | Not applicable | Withdrawn | Norfolk and Norwich University Hospitals NHS Foundation Trust | 2025-01-01 | 2026-06-09 | |
| Fisetin to Reduce Senescence and Mobility Impairment in PAD Fisetin, Placebo - Peripheral Arterial Disease, Aging | Phase 2 | Recruiting | Northwestern University | 34 | 2024-09-30 | 2026-04-15 |
| The Effects of Diet and Exercise Interventions in Peripheral Artery Disease DASH Diet plus Home-Based Exercise, Home-Based Exercise - Claudication, Peripheral Artery Disease | Not applicable | Recruiting | University of Oklahoma | 150 | 2024-09-16 | 2026-04-17 |
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Peripheral Arterial Disease (200) · Peripheral Vascular Diseases (67) · Atherosclerosis (34) · Chronic Limb-Threatening Ischemia (34) · Motor Activity (18) · Arterial Occlusive Diseases (17) · Vascular Diseases (15) · Cardiovascular Diseases (14) · Peripheral Arterial Occlusive Disease 1 (9) · Inflammation (6) · Spinal Stenosis (5) · Arteriosclerosis (4) · Mobility Limitation (4) · Thrombosis (4)
Pathological Conditions, Signs and Symptoms (306) · Signs and Symptoms (304) · Cardiovascular Diseases (292) · Vascular Diseases (291) · Peripheral Vascular Diseases (239) · Arteriosclerosis (218) · Arterial Occlusive Diseases (212) · Atherosclerosis (187) · Peripheral Arterial Disease (106) · Pathologic Processes (48) · Chronic Disease (35) · Disease Attributes (35) · Ischemia (34) · Behavior (22) · Nervous System Diseases (13)
Exercise (15) · Cilostazol (13) · Angioplasty (12) · Aspirin (7) · Clopidogrel (4) · Exercise Therapy (4) · Atherectomy (3) · BID protein, human (3) · Control Groups (3) · Exercise Test (3) · Stents (3) · Acupuncture Therapy (2) · Arginine (2) · Intermittent Pneumatic Compression Devices (2) · Lovastatin (2)
University Hospital, Angers (11) · Abbott Medical Devices (6) · Genovate Biotechnology Co., Ltd., (6) · Medtronic Endovascular (6) · Northwestern University (6) · Copenhagen University Hospital at Herlev (5) · Hull University Teaching Hospitals NHS Trust (5) · National Heart, Lung, and Blood Institute (NHLBI) (5) · Sahlgrenska University Hospital (5) · Flanders Medical Research Program (4) · Imperial College London (4) · Norwegian University of Science and Technology (4) · University of California, San Francisco (4) · University of Minnesota (4) · University of Oklahoma (4)
United States (118) · Germany (30) · United Kingdom (26) · France (20) · Austria (15) · Belgium (13) · Sweden (12) · Brazil (10) · Denmark (10) · Netherlands (9) · New Zealand (9) · Canada (8) · Norway (7) · South Korea (7) · Italy (6)
Marc Bosiers, MD (4) · Henrik S Thomsen, Prof. MD. (3) · Pierre Abraham, MD, PhD (3) · Raphael Ritti-Dias, PhD (3) · Thomas Zeller, MD (3) · Andrew W Gardner, PhD (2) · Andrew W. Gardner, PhD (2) · Daniel V Freeland, DO (2) · Gabriel Cucato, PhD (2) · Garry A Tew, PhD (2) · John H. Rundback, M.D. (2) · Jonny Hisdal, PhD (2) · Manish Mehta, MD, MPH (2) · Oliver O Aalami, MD (2)
PMID 21262997, PMID 25237048, PMID 42573020, PMID 16242558, PMID 31912491, PMID 42035974, PMID 10650308, PMID 10666287, PMID 10777236, PMID 10805617, PMID 1100130, PMID 11034229, PMID 11300450, PMID 11368702, PMID 11454114, PMID 11581152, PMID 11789964, PMID 11790215, PMID 12042688, PMID 12485966, PMID 12495171, PMID 12610004, PMID 12668524, PMID 12850465, PMID 14981444, PMID 15389223, PMID 15451914, PMID 15678616, PMID 16449620, PMID 16520719, PMID 16678694, PMID 17026909, PMID 17110509, PMID 17126520, PMID 17223489, PMID 17264010, PMID 17299195, PMID 17353883, PMID 17374814, PMID 17543683, PMID 17617342, PMID 18270378, PMID 18362433, PMID 18388038, PMID 18612130, PMID 18628657, PMID 18675557, PMID 18774340, PMID 18783958, PMID 19028055
1RC2HL101515-01 (1), 2004 (1), 2005 (1), 2009 (1), 2017 (1), I01CX002150 (1), I21RX001927 (1), K01AG000657 (1), K01HL115534 (1), R01AG016685 (1), R01AG024296 (1), R01AG034995 (1), R01AG057693 (1), R01AG070086 (1), R01AG071778 (1)