18 completed. 18 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 18 | Completed 18 |
Follow Knee Injuries: new trials by email Literature Review of Knee Injuries trials Research Report on Knee Injuries
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Nalbuphine With Remimazolam Versus Nalbuphine With Propofol for Knee Arthroscopy Nalbuphine, Remimazolam, Propofol - Knee Injuries | Phase 4 | Completed | Wuhan Fourth Hospital | 100 | 2025-04-10 | 2026-09-24 |
| Genicular Nerve Blocks for Anterior Cruciate Ligament Knee Surgery Genicular Nerve Block with bupivacaine and preservative free dexamethasone - ACL, Anterior Cruciate Ligament Injuries | Phase 4 | Completed | Hospital for Special Surgery, New York | 192 | 2023-01-12 | 2026-01-26 |
| iPACK for Post-op Pain Following ACL Reconstruction Adductor Canal Block (ACB) Only, Adductor Canal Block (ACB) + iPACK Block - ACL Injury, Post Operative Pain | Phase 4 | Completed | Medical University of South Carolina | 82 | 2022-08-25 | 2024-10-16 |
| Adductor Canal Block and IPACK Block vs. Isolated Adductor Canal Block for Post-Operative Analgesia Following ACL Reconstruction With Bone Patellar Tendon Bone Autograft: IPACK block - Anterior Cruciate Ligament Rupture | Phase 4 | Completed | NYU Langone Health | 102 | 2022-07-11 | 2024-04-26 |
| Are Opioids Needed After ACL Reconstruction Oxycodone, Placebo oral tablet - Anterior Cruciate Ligament Rupture | Phase 4 | Completed | Emory University | 98 | 2020-09-16 | 2023-10-11 |
| A Novel Analgesia Technique for ACL Reconstruction Bupivacaine, Ultrasound, Dexamethasone - Anterior Cruciate Ligament Injury | Phase 4 | Completed | Hospital for Special Surgery, New York | 78 | 2017-10-04 | 2024-09-19 |
| Effect of PRP Injection After Arthroscopic Meniscal Repair in the Healing Process platelet rich plasma - Knee Pain, Knee Injuries | Phase 4 | Completed | Alexandria University | 30 | 2017-03-03 | 2019-04-11 |
| Clinical Comparison of Femoral Nerve Versus Adductor Canal Block Following Anterior Ligament Reconstruction 30 ml of 0.2% ropivacaine, 15 ml of 0.2% ropivacaine, 100 mcg clonidine - Anterior Cruciate Ligament Injury | Phase 4 | Completed | The University of Texas Health Science Center, Houston | 125 | 2016-02-01 | 2021-10-21 |
| Adductor Canal Block Versus Femoral Block on Pain and Quadriceps Strength Femoral Nerve Block, Adductor Canal Nerve Block, preoperative Femoral Nerve Block using 20ml of 0.5% ropivacaine - Anterior Cruciate Ligament Tear, Knee Meniscus Tear | Phase 4 | Completed | University of California, San Francisco | 132 | 2016-01-01 | 2025-09-30 |
| Local Infiltration Analgesia vs Adductor Canal Block for Analgesia After Anterior Cruciate Ligament Reconstruction Ropivacaine 0.5% 20 mLs - Rupture of Anterior Cruciate Ligament, Infiltration | Phase 4 | Completed | Centre Hospitalier Universitaire Vaudois | 104 | 2015-09-01 | 2018-05-07 |
| Liposomal Bupivacaine for Pain Control Following Anterior Cruciate Ligament Reconstruction Exparel - Anterior Cruciate Ligament Rupture | Phase 4 | Completed | Emory University | 50 | 2014-08-01 | 2016-07-27 |
| Ultrasound-guided Adductor Canal Block for Total Knee Replacement Bupivacaine, Preservative free normal saline - Complications; Arthroplasty, Knee Injuries | Phase 4 | Completed | Northwestern University | 40 | 2014-03-01 | 2017-07-11 |
| Simultaneous Multiple Cruciate Ligament Reconstructions Using a Single Achilles Allograft cruciate ligament reconstruction - Rupture of Posterior Cruciate Ligament, Rupture of Anterior Cruciate Ligament | Phase 4 | Completed | National Police Hospital | 51 | 2011-05-01 | 2011-09-26 |
| Comparison of Infiltration Analgesia With Femoral Nerve Block After Hamstrings Anterior Cruciate Ligament Reconstruction Femoral nerve block, Local infiltration analgesia - Injury of Anterior Cruciate Ligament | Phase 4 | Completed | University of Aarhus | 60 | 2010-11-01 | 2012-05-02 |
| Acute Pain and Inflammation After Surgery 1 Ketorolac intraarticular, Placebo - Knee Injuries | Phase 4 | Completed | Oslo University Hospital | 40 | 2008-08-01 | 2015-04-23 |
| Evaluation of Biocleanse Allografts For ACL Reconstruction ACL reconstruction control, ACL Biocleanse, surgical - Anterior Cruciate Ligament Tear | Phase 4 | Completed | University of Florida | 67 | 2004-02-01 | 2014-03-04 |
| COX-2 Inhibitor Versus Glucocorticoid Versus Both Combined parecoxib, valdecoxib, etoricoxib, Dexamethasone, parecoxib, valdecoxib, parecoxib and dexamethasone - Rupture of Anterior Cruciate Ligament | Phase 4 | Completed | Asker & Baerum Hospital | 93 | 2004-01-01 | 2011-05-27 |
| Pain Relief Results After Anterior Cruciate Ligament (ACL) Reconstruction Single-injection femoral nerve block, Femoral nerve block 60-hour continuous injection, Saline (control) injection into femoral nerve envelope - Anterior Cruciate Ligament Rupture | Phase 4 | Completed | University of Pittsburgh | 270 | 2001-05-01 | 2013-05-03 |
Anterior Cruciate Ligament Injuries (14) · Acute Pain (1) · Agnosia (1) · Pain (1) · Pain, Postoperative (1)
Leg Injuries (18) · Wounds and Injuries (18) · Neurologic Manifestations (3) · Pathological Conditions, Signs and Symptoms (3) · Signs and Symptoms (3) · Pain (2) · Nervous System Diseases (1) · Neurobehavioral Manifestations (1) · Pathologic Processes (1) · Perceptual Disorders (1) · Postoperative Complications (1)
Bupivacaine (3) · Ropivacaine (3) · Sodium Chloride (3) · Dexamethasone (2) · Calcium Dobesilate (1) · Clonidine (1) · Etoricoxib (1) · Ketorolac (1) · Nalbuphine (1) · Oxycodone (1) · Propofol (1) · Single Person (1) · Surgical Procedures, Operative (1) · Ultrasonography (1) · parecoxib (1)
Emory University (2) · Hospital for Special Surgery, New York (2) · Alexandria University (1) · Asker & Baerum Hospital (1) · Centre Hospitalier Universitaire Vaudois (1) · Medical University of South Carolina (1) · NYU Langone Health (1) · National Police Hospital (1) · Northwestern University (1) · Oslo University Hospital (1) · The University of Texas Health Science Center, Houston (1) · University of Aarhus (1) · University of California, San Francisco (1) · University of Florida (1) · University of Pittsburgh (1)
United States (11) · Norway (2) · China (1) · Denmark (1) · Egypt (1) · South Korea (1) · Switzerland (1)
John Xerogeanes, MD (2) · Antoun Nader, MD (1) · Brian A. Williams, MD, MBA (1) · Carey Breabaker, MD (1) · David H Kim, MD (1) · Eric Albrecht, PD Dr (1) · Eric J Strauss, MD (1) · Jashvant Poeran, MD/PhD (1) · Jonathan Beathe, MD (1) · Jung Ho Noh, M.D., Ph.D. (1) · Lane Bailey, PhD, PT (1) · Leiv Arne Rosseland (1) · Pedram Aleshi, MD (1) · Peter A. Indelicato, M.D. (1) · Rehab A ELnemr, lecturer (1)
PMID 16436852, PMID 17377133, PMID 17456710, PMID 17543812, PMID 17543813, PMID 18042869, PMID 18073577, PMID 23338666, PMID 27159290, PMID 30733025, PMID 31130273, PMID 31348866, PMID 34477016, PMID 36860772, PMID 37152546, PMID 40308075, PMID 42459597
2004 (1), K23AR047631 (1)