28 completed, 14 unknown, 5 terminated, 3 not yet recruiting. 25 Phase 4, 12 Not applicable, 10 Phase 3, 5 Phase 2, 1 Phase 1.
Follow parecoxib: new trials by email Literature Review of parecoxib trials Research Report on parecoxib
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pre-Emptive Parecoxib Sodium for Pain Control During CT-Guided Lung Nodule Localization PARECOXIB SODIUM, 0.9 % Normal Saline - Lung Nodules | Phase 4 | Recruiting | Long Jiang | 150 | 2026-06-01 | 2026-06-30 |
| Analgesic Effect of Parecoxib Versus Morphine in SCD Patients Presenting to the Emergency Department Parecoxib, Morphine - Sickle-Cell Disease with Crisis | Phase 3 | Not yet recruiting | Oman Medical Speciality Board | 226 | 2026-05-01 | 2025-03-20 |
| Study Comparing Dynastat and Parestat Pain Relief Medications for Patients After Breast Surgery Parestat(generic parecoxib), Dynastat (original Parecoxib) - Breast Exicision Biopsy | Phase 4 | Not yet recruiting | University of Malaya | 60 | 2025-10-01 | 2025-09-22 |
| Comparative Efficacy of IV Parecoxib vs Lidocaine in Reducing Propofol Injection Pain Lidocaine, a local anaesthetic., Parecoxib 40mg - Preventing Propofol Pain on Injection | Not applicable | Not yet recruiting | Oman Medical Speciality Board | 30 | 2025-08-01 | 2025-08-11 |
| Evaluation of the Safety and Efficacy of Parecoxib in Patients With Subarachnoid Hemorrhage Parecoxib, Placebo - Neurological Complication | Phase 2 | Recruiting | St. Anne's University Hospital Brno, Czech Republic | 112 | 2025-01-01 | 2026-08-21 |
| Bioequivalence of Two Formulations of Parecoxib in Healthy Volunteers Under Fasting Conditions Parecoxib - Post-operative Pain, Bioequivalence Study in Healthy Subjects | Phase 4 | Unknown | Yung Shin Pharm. Ind. Co., Ltd. | 14 | 2024-10-01 | 2024-09-20 |
| Efficacy and Safety of Parecoxib vs. Indomethacin in Preventing Post-ERCP Pancreatitis Parecoxib Sodium, Indomethacin suppository - Pancreatitis, Acute, Cholangiopancreatography, Endoscopic Retrograde | Phase 2 | Unknown | Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine | 100 | 2024-10-01 | 2024-10-02 |
| Effect of Paracetamol and Mannitol Injection on Postoperative Analgesia in Patients With Thoracoscopic Lobectomy Paracetamol and Mannitol Injection, Parecoxib - Postoperative Analgesia | Not applicable | Unknown | The Fourth Affiliated Hospital of Zhejiang University School of Medicine | 90 | 2024-03-15 | 2024-03-12 |
| Preemptive Analgesic Efficacy of Parecoxib for Reducing Postoperative Pain in Gynecological Surgery Parecoxib, Normal saline - Preemptive Analgesia, Gynecological Surgery | Phase 4 | Completed | Department of Medical Services Ministry of Public Health of Thailand | 178 | 2023-09-10 | 2024-11-14 |
| Efficacy of Parecoxib Combined With Paracetamol in Mastectomy Parecoxib + paracetamol, Normal saline - Post Operative Pain | Not applicable | Unknown | Khon Kaen University | 60 | 2023-03-28 | 2023-04-14 |
| Accelerated Recovery Following Opioid-free Anaesthesia in Supratentorial Craniotomy Lignocaine, Dexmedetomidine, Sevoflurane, Paracetamol, Parecoxib - Opioid-Free Anaesthesia | Not applicable | Completed | University of Malaya | 25 | 2023-01-01 | 2024-04-09 |
| Optimized Acute Pain Control With Parecoxib in Uniportal Video-assisted Thoracoscopic Surgery. Parecoxib, Placebo - Perioperative Care, Chronic Post-operative Pain | Phase 4 | Completed | National Taiwan University Hospital | 58 | 2021-12-15 | 2023-08-02 |
| Regional Scalp Block Versus IV Parecoxib for Post-operative Cranioplasty Surgery Pain: A Comparison of Pain Score. Ropivacaine 0.75% Injectable Solution - Postoperative Pain | Phase 1 | Completed | Universiti Sains Malaysia | 58 | 2021-03-09 | 2022-07-05 |
| Pain Management After Transnasal Transsphenoidal Surgery for Pituitary Adenomas NSAID, Tramadol - Pituitary Adenoma, Surgery | Not applicable | Unknown | Peking Union Medical College Hospital | 202 | 2020-10-31 | 2020-11-03 |
| Parecoxib as an Adjuvant to Scalp Nerve Blocks for Relief of Post-craniotomy Pain Scalp blocks with ropivacaine plus parecoxib, Scalp blocks with ropivacaine and intravenous parecoxib, Scalp blocks with ropivacaine and intravenous saline - Pain, Postoperative, Neurosurgery | Phase 4 | Unknown | Beijing Tiantan Hospital | 132 | 2019-10-12 | 2020-06-16 |
| Parecoxib vs. Dexketoprofen for the Management of Pain After Cesarean Section. Parecoxib, Dexketoprofen - Caesarean Section; Pain | Not applicable | Completed | Saint Thomas Hospital, Panama | 380 | 2019-07-01 | 2021-10-11 |
| Parecoxib vs Paracetamol in the Treatment of Acute Renal Colic Paracetamol, Parecoxib - Acute Renal Colic, Ureteric Stone | Phase 4 | Completed | Mansoura University | 200 | 2019-05-01 | 2020-08-28 |
| Effect of Intravenous Dynastat on Postoperative Sore Throat Parecoxib Injectable Product, Normal saline - Sore Throat, Postoperative Complications | Phase 2 | Unknown | Buddhist Tzu Chi General Hospital | 140 | 2019-03-01 | 2019-04-16 |
| the Effect of Doctor-nurse-patient Cooperative Analgesic Linkage Program on Movement Evoked Pain Routine Dezocine injection, Adjusted Dezocine injection, Routine Dynastat or Flurbiprofen Axetil jinjection - Pain, Postoperative, Anaplasia | Not applicable | Unknown | Second Affiliated Hospital, Zhejiang University, School of Medicine | 80 | 2017-11-01 | 2020-02-12 |
| The Epigenetic Modification in OPRM1 on Postoperative Analgesia and Side Effect Induced by Sufentanil Sufentanil, dexmedetomidine, propofol - Epigenetics | Phase 4 | Unknown | Huazhong University of Science and Technology | 100 | 2017-02-06 | 2017-05-01 |
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Pain, Postoperative (22) · Pain (8) · Agnosia (6) · Hyperalgesia (2) · Inflammation (2) · Shoulder Pain (2) · Anaplasia (1) · Anterior Cruciate Ligament Injuries (1) · Bronchiolitis Obliterans Syndrome (1) · Carcinoma, Hepatocellular (1) · Causalgia (1) · Colic (1) · Complex Regional Pain Syndromes (1) · Emergence Delirium (1) · Gastrointestinal Neoplasms (1)
Pfizer (8) · Peking Union Medical College Hospital (4) · First Affiliated Hospital, Sun Yat-Sen University (3) · Oman Medical Speciality Board (2) · Ruhr University of Bochum (2) · Sun Yat-sen University (2) · Universiti Sains Malaysia (2) · University of Malaya (2) · Asker & Baerum Hospital (1) · Asklepieion Voulas General Hospital (1) · Beijing Tiantan Hospital (1) · Buddhist Tzu Chi General Hospital (1) · Chang Gung Memorial Hospital (1) · Chiang Mai University (1) · Department of Medical Services Ministry of Public Health of Thailand (1)
China (18) · Malaysia (4) · Thailand (4) · Germany (3) · Norway (3) · Taiwan (3) · Argentina (2) · Australia (2) · Czechia (2) · Finland (2) · Greece (2) · Italy (2) · Austria (1) · Belgium (1) · Brazil (1)
Abdullatif AL-Terki, MD (1) · Ahmad Fariz Elias (1) · Audun Stubhaug, Prof.,MD,PhD (1) · Bing Xing, MD (1) · Caijuan Xu, master (1) · Christoph Maier, Professor (1) · Elina Tiippana, M.D. (1) · Fang Luo, M.D. (1)
PMID 10995141, PMID 11465874, PMID 15232360, PMID 15777293, PMID 17577465, PMID 19095866, PMID 24480836, PMID 25767411, PMID 25886746, PMID 26171894, PMID 26801163, PMID 26861666, PMID 27158989, PMID 27609846, PMID 27622453, PMID 29962529, PMID 31924632
2004 (1), 2008 (1), 2009 (1)