30 completed, 11 unknown, 10 recruiting, 4 active not recruiting. 33 Not applicable, 10 Phase 2, 6 Phase 3, 3 Phase 4, 1 Early Phase 1.
Follow Joint Pain: new trials by email Literature Review of Joint Pain trials Research Report on Joint Pain
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Evaluation of the Efficacy and Acceptability of a Phytotherapy Combining Devil's Claw, Blackcurrant and Meadowsweet for the Management of Aromatase Inhibitor-induced Arthralgia in Patients Treated for Localized Breast Cancer in the Adjuvant Setting Phytotherapy Dietary Supplement (Harpagophytum, Meadowsweet, and Blackcurrant), Patient Experience Questionnaire - Hormone Therapy-induced Arthralgia, Phytotherapy | Phase 4 | Not yet recruiting | Hospices Civils de Lyon | 105 | 2027-01-01 | 2026-11-03 |
| Pilot Study of Hydroxychloroquine for the Treatment of AIMSS Hydroxychloroquine Sulfate (HCQ) - Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS), Joint Pain | Phase 2 | Recruiting | Indiana University | 35 | 2026-10-19 | 2026-11-10 |
| Effects of Maine Oils on Joint Stiffness and Pain Herring oil, Omega-11 concentrate produced from herring oi, Control oil - Joint Pain, Joint Stiffness | Not applicable | Not yet recruiting | University of Bergen | 150 | 2026-08-01 | 2026-08-25 |
| Dietary Supplements and Middle Aged Women (Collagen & Omega) Collagen peptides and omega-3, Placebo control - Cognition, Inflammation Biomarkers | Not applicable | Recruiting | Loughborough University | 34 | 2026-05-01 | 2026-08-03 |
| Dietary Supplements and Middle Aged Women (Creatine) Creatine Monohydrate, Placebo control - Cognition, Muscle Strength | Not applicable | Recruiting | Loughborough University | 38 | 2026-05-01 | 2026-07-28 |
| A Controlled Study to Evaluate the Effects of a Topical Cream on Symptoms of Arthritis, Joint, and Muscle Pain Intervention (Saje Pain Release Joint & Arthritis Cream), Placebo Comparator - Arthritis, Joint Pain | Not applicable | Completed | Saie Beauty | 80 | 2026-02-01 | 2026-08-17 |
| Tart Cherry and Omega-3's for Aromatase Inhibitor Musculoskeletal Symptoms Tart Cherry, Omega 3 FA (Fish Oil) - Breast Cancer, Aromatase Inhibitor Associated Musculoskeletal Symptoms (AIMSS) | Early Phase 1 | Recruiting | Philip Chang | 30 | 2025-09-12 | 2026-08-04 |
| Evaluating the Auricular Point Acupressure-Self Management Program for Chronic Musculoskeletal Pain Among Rural Populations Auricular Point Acupressure (APA) - Self Management (SM), Education Control - Chronic Pain (Back / Neck), Chronic Pain Management | Not applicable | Recruiting | The University of Texas Health Science Center, Houston | 693 | 2025-09-11 | 2025-10-01 |
| Dietary Wild Blueberries and Joint Health Wild blueberry, Placebo - Gut -Microbiota, Inflammation Biomarkers | Not applicable | Recruiting | University of Nevada, Las Vegas | 50 | 2025-09-01 | 2025-11-05 |
| JDS-HF3.0 Supplementation on Menopause Related Quality of Life Outcomes in Postmenopausal Women JDS-HF3.0, Placebo - Joint Discomfort, Joint Pain, Stiffness, Function | Not applicable | Recruiting | Bonafide Health | 250 | 2025-05-14 | 2025-11-20 |
| Genicular Nerve Phenol Neurolysis Versus Radiofrequency Ablation for Pain Relief in Grade 4 Knee Osteoarthritis genicular nerve neurolysis - Joint Pain | Not applicable | Not yet recruiting | Ain Shams University | 114 | 2025-04-01 | 2025-03-07 |
| The Effect of LDL557 on Improving Degenerative Arthritis in the Elderly LDL557-HK capsule, Placebo Capsule - Arthritis, Joint Pain | Not applicable | Enrolling by invitation | Chung Shan Medical University | 100 | 2025-02-27 | 2026-08-17 |
| Effect of Maolactin™ FMR on Exercise Recovery, Inflammation and Muscle Comfort in an Otherwise Healthy Population Maolactin, Maltodextrin - Chronic Inflammation, Mobility | Phase 3 | Completed | RDC Clinical Pty Ltd | 97 | 2025-02-27 | 2026-11-13 |
| A Study to Evaluate Efficacy, Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of LEO 158968 LEO 158968 - Joint Pain, Gout Flares | Phase 1 | Completed | LEO Pharma | 6 | 2025-01-07 | 2026-05-12 |
| Efficacy and Safety of Celecoxib/Acetaminophen Versus Celecoxib for Diagnosed Osteoarthritis in Acute Exacerbation Celecoxib + Acetaminophen, Celecoxib - Joint Pain, Knee Osteoarthritis | Phase 3 | Completed | Laboratorios Silanes S.A. de C.V. | 231 | 2024-09-09 | 2026-10-23 |
| The MUSE Study for Menopausal Arthralgia Menopausal hormone therapy, Exercise training, Menopausal hormone therapy + exercise training - Arthralgia, Menopause | Phase 2 / Phase 3 | Recruiting | National University Hospital, Singapore | 100 | 2024-08-01 | 2024-07-31 |
| Prevalence of Muscle and Nerve and Joint Pain muscle pain , joint pain and nerve pain. - Muscle Pain, Joint Pain | Unknown | Hadeer Gomaa Ebraheem Aly | 300 | 2024-02-01 | 2024-05-07 | |
| Effectiveness of Cucumber Extract on Joint Pain Q Actin - Joint Pain | Not applicable | Unknown | Jacksonville University | 80 | 2024-02-01 | 2024-02-07 |
| Subsartorial Nerve Block and Femoral Nerve Block in Total Knee Arthroplasty SSNB + IPACK, FNB + IPACK - Joint Diseases, Joint Pain | Not applicable | Recruiting | Luzerner Kantonsspital | 144 | 2023-11-30 | 2024-03-12 |
| Topical Cannabis for Chronic Musculoskeletal Pain Chronic Pain, Musculoskeletal Pain | Unknown | University of Colorado, Denver | 77 | 2023-07-01 | 2023-06-18 |
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Arthralgia (64) · Myalgia (9) · Breast Neoplasms (8) · Chronic Pain (7) · Osteoarthritis, Knee (7) · Arthritis (6) · Musculoskeletal Pain (6) · Osteoarthritis (5) · Pain (5) · Osteoarthritis, Hip (4) · Arthritis, Rheumatoid (3) · Inflammation (3) · Joint Diseases (3) · Low Back Pain (3) · Emergencies (2)
Neurologic Manifestations (64) · Pathological Conditions, Signs and Symptoms (64) · Signs and Symptoms (64) · Musculoskeletal Diseases (63) · Joint Diseases (61) · Pain (59) · Muscular Diseases (14) · Arthritis (12) · Rheumatic Diseases (12) · Skin and Connective Tissue Diseases (12) · Nervous System Diseases (9) · Neuromuscular Diseases (9) · Breast Diseases (8) · Musculoskeletal Pain (8) · Neoplasms (8)
Chondroitin (3) · Glucosamine (3) · Acetaminophen (2) · Walking (2) · fulranumab (2) · Aromatase Inhibitors (1) · CelE protein, bacteria (1) · Celecoxib (1) · Cholecalciferol (1) · Chondroitin Sulfates (1) · Collagen Type II (1) · Creatine (1) · Curcumin (1) · Diarylheptanoids (1) · Diet Therapy (1)
Vedic Lifesciences Pvt. Ltd. (3) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (2) · Loughborough University (2) · Stanford University (2) · University of Memphis (2) · Ain Shams University (1) · Baylor Breast Care Center (1) · Bioiberica (1) · Bonafide Health (1) · Brigham and Women's Hospital (1) · CHRISTUS Health (1) · Chang Gung Memorial Hospital (1) · Chung Shan Medical University (1) · City of Hope Medical Center (1) · Dawn L. Hershman (1)
United States (29) · France (5) · Spain (5) · Canada (3) · India (3) · United Kingdom (3) · Egypt (2) · Netherlands (2) · Poland (2) · South Korea (2) · Taiwan (2) · Australia (1) · China (1) · Croatia (1) · Denmark (1)
Richard Bloomer, PhD (2) · Adelfia Urenda-Quezada, MD (1) · Ahmed Boeith, MD (1) · Albert Leung, M.D. (1) · Alice C. Shapiro, PhD RD (1) · David Briskey, PhD (1) · Dawn Hershman, MD (1) · Dr. Shalini Srivastava, MBBS, MD (1) · Elisabeth Simon, Pharm Dr (1) · Emily Lindley, PhD (1) · Eshwari Koovor, M.B.B.S. (1) · Fred Cushner, MD (1) · Herjit Pannu, MD (1)
PMID 25818278, PMID 26868123, PMID 27238963, PMID 27748055, PMID 28768617, PMID 28778219, PMID 34067240, PMID 35676017, PMID 38280052, PMID 39768214, PMID 40636535, PMID 41787523, PMID 42259555, PMID 42663526
2009 (2), 2023 (2), R61NS118651 (1), UG1CA189823 (1)