13 completed, 3 unknown, 1 recruiting. 7 Not applicable, 6 Phase 4, 3 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Completed 5, Recruiting 1, Unknown 1 |
| Phase 4 | 6 | Completed 4, Unknown 2 |
| Phase 3 | 3 | Completed 3 |
| Phase 2 | 1 | Completed 1 |
Follow Chondroitin: new trials by email Literature Review of Chondroitin trials Research Report on Chondroitin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Clinical Study to Evaluate the Efficacy of Native CT-II® in Individuals With Knee Osteoarthritis Native CT-II® (undenatured type II collagen), Glucosamine HCL + Chondroitin Sulphate (G+C) [Comparator], Placebo [Microcrystalline Cellulose (MCC) - Knee Osteoarthritis (OA) | Not applicable | Completed | Vedic Lifesciences Pvt. Ltd. | 114 | 2025-04-20 | 2026-10-01 |
| NT-II™ Collagen for Joint Discomfort and Function NT-II™ (240 mg), NT-II™ 480 mg, Glucosamine/Chondroitin - Activity-Related Knee Discomfort, Joint Discomfort | Not applicable | Recruiting | Hofseth Biocare ASA | 120 | 2025-01-20 | 2026-05-14 |
| Efficacy of Bioactive Collagen Peptide Compared to Glucosamine and Chondroitin Sulphate in Grade I-III Knee Osteoarthritis Bioactive Collagen Peptide, Glucosamine and Chondroitin Sulphate - Knee Osteoarthritis (Kellgren-Lawrence Grade 1-3) | Not applicable | Completed | Liaquat National Hospital & Medical College | 150 | 2023-06-01 | 2026-08-10 |
| Clinical Study to Evaluate the Effect of Different Doses of UC-II® Supplementation on the Range of Motion & Joint Discomfort in Healthy Subjects Collagen type II (40 mg/day), Collagen type II (80mg/day), Collagen type II (120 mg/day) - Joint Pain | Not applicable | Unknown | Vedic Lifesciences Pvt. Ltd. | 375 | 2022-10-10 | 2022-11-30 |
| Effect of Interventions on the Progression of Knee Osteoarthritis Diacerien, Glucosamine/Chondroitin, Placebo - Osteo Arthritis of the Knees | Phase 4 | Completed | Indus Hospital and Health Network | 322 | 2014-06-01 | 2018-03-01 |
| Efficacy of IARULIL® in the Treatment of Recurrent Cystitis Refractory to Escherichia Coli Extract hyaluronic acid and chondroitin sulphate - Recurrent Cystitis | Phase 4 | Completed | Samsung Medical Center | 105 | 2014-01-01 | 2019-12-02 |
| Efficacy and Safety of PRO-148 Versus Systane®, in Patients With Mild to Moderate Dry Eye PRO-148, Systane - Dry Eye | Phase 3 | Completed | Laboratorios Sophia S.A de C.V. | 183 | 2013-11-01 | 2017-12-15 |
| Glucosamine and Chondroitin Effects Glucosamine and Chondroitin, placebo - Inflammation | Not applicable | Completed | Fred Hutchinson Cancer Center | 20 | 2012-09-01 | 2014-05-28 |
| Study on Efficacy and Safety of Chondroitin Sulfate + Glucosamine Hydrochloride Versus Celecoxib in Knee Osteoarthritis Chondroitin/Glucosamine (Droglican), Celecoxib - Knee Osteoarthritis | Phase 4 | Completed | Bioiberica | 606 | 2011-09-01 | 2016-02-26 |
| Study to Evaluate the Safety and Efficacy of a Proprietary "Joint Health" Dietary Supplement in Subjects With Joint and Connective Tissue Pain Joint Health Product, Placebo, Glucosamine / Chondroitin - Joint Pain | Not applicable | Completed | U.S. Nutraceuticals, LLC | 135 | 2010-10-08 | 2017-07-06 |
| Assessment of the Effects of Chondroitin Sulphate in Patients With Knee Osteoarthritis With Functional Magnetic Resonance Imaging (fMRI) Chondroitin sulphate (Condrosan®), Placebo - Knee Osteoarthritis | Phase 4 | Unknown | Bioiberica | 64 | 2010-10-01 | 2012-10-02 |
| Efficacy and Safety Study of Glucosamine/Chondroitin Sulfate to Patients Treatment With Osteoarthrosis of the Knee Glucosamine sulphate and chondroitin sulphate association, Cosamin DS® (Nutramax) - Osteoarthritis of the Knee | Phase 3 | Completed | Eurofarma Laboratorios S.A. | 100 | 2010-08-01 | 2023-02-08 |
| Glucosamine and Chondroitin for Aromatase Inhibitor Induced Joint Symptoms in Women With Breast Cancer Chondroitin, Glucosamine - Breast Cancer, Joint Pain | Phase 2 | Completed | Dawn L. Hershman | 53 | 2008-10-01 | 2022-11-08 |
| Effect of Chondroitin Sulphate on Synovial Inflammation in Patients With Osteoarthritis of the Knee Chondroitin sulphate (Condrosan), Placebo - Synovitis, Osteoarthritis | Phase 3 | Completed | Bioiberica | 70 | 2008-02-01 | 2011-12-19 |
| The Long-term Evaluation of Glucosamine Sulphate Study Glucosamine sulphate and chondroitin, Glucosamine sulphate, Chondroitin sulphate - Osteoarthritis, Knee | Phase 4 | Unknown | University of Sydney | 600 | 2007-10-01 | 2010-06-30 |
| Absorption and Distribution of Glucosamine and Chondroitin Glucosamine, Chondroitin - Osteoarthritis | Not applicable | Completed | National Center for Complementary and Integrative Health (NCCIH) | 70 | 2004-04-01 | 2006-08-18 |
| Chondroitin Sulphate Efficay/Safety in Patients With Knee Osteoarthritis and Psoriasis Chondroitin sulphate, Placebo - Osteoarthritis, Psoriasis | Phase 4 | Completed | Bioiberica | 126 | 2008-04-29 |
Osteoarthritis, Knee (8) · Osteoarthritis (4) · Arthralgia (3) · Inflammation (2) · Joint Diseases (2) · Breast Neoplasms (1) · Chronic Pain (1) · Cystitis (1) · Disease Progression (1) · Dry Eye Syndromes (1) · Psoriasis (1) · Skin Diseases (1) · Synovitis (1)
Bioiberica (4) · Vedic Lifesciences Pvt. Ltd. (2) · Dawn L. Hershman (1) · Eurofarma Laboratorios S.A. (1) · Fred Hutchinson Cancer Center (1) · Hofseth Biocare ASA (1) · Indus Hospital and Health Network (1) · Laboratorios Sophia S.A de C.V. (1) · Liaquat National Hospital & Medical College (1) · National Center for Complementary and Integrative Health (NCCIH) (1) · Samsung Medical Center (1) · U.S. Nutraceuticals, LLC (1) · University of Sydney (1)
United States (5) · Spain (3) · India (2) · Pakistan (2) · Australia (1) · Brazil (1) · Canada (1) · Mexico (1) · South Korea (1)
Jordi Monfort, MD (2) · Charles Bridges-Webb, MB, BS (1) · Christopher G. Jackson, MD (1) · Cristiano F. Zerbini, Phd/MD (1) · Dawn Hershman, MD (1) · Eshwari Koovor, M.B.B.S. (1) · Herjit Pannu, MD (1) · Jean-Pierre Pelletier, Prof., Dr. (1) · Johanne Martel-Pelletier, Prof., Dr. (1) · John Edmonds, MB,BS (1) · Kyu-Sung Lee, M.D., Ph.D. (1)
PMID 20399899, PMID 21367761, PMID 23647688, PMID 24395557, PMID 25589511, PMID 25719429, PMID 27645318, PMID 30657100, PMID 34088340