35 completed, 10 unknown, 2 recruiting, 2 terminated. 17 Not applicable, 12 Phase 3, 10 Phase 4, 5 Phase 1, 3 Phase 2.
Follow Glucosamine: new trials by email Literature Review of Glucosamine trials Research Report on Glucosamine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Human Absorption Study of Liposomal Glucosamine Supplements High-Emulsified Liposomal Glucosamine Liquid, Low-Emulsified Liposomal Glucosamine Liquid, Glucosamine Liquid without Liposomal - Glucosamine, Liposomal Encapsulation | Not applicable | Recruiting | TCI Co., Ltd. | 16 | 2026-10-21 | 2026-09-28 |
| A Clinical Study to Evaluate the Efficacy of Native CT-II® in Individuals With Knee Osteoarthritis Native CT-II® (undenatured type II collagen), Glucosamine HCL + Chondroitin Sulphate (G+C) [Comparator], Placebo [Microcrystalline Cellulose (MCC) - Knee Osteoarthritis (OA) | Not applicable | Completed | Vedic Lifesciences Pvt. Ltd. | 114 | 2025-04-20 | 2026-10-01 |
| NT-II™ Collagen for Joint Discomfort and Function NT-II™ (240 mg), NT-II™ 480 mg, Glucosamine/Chondroitin - Activity-Related Knee Discomfort, Joint Discomfort | Not applicable | Recruiting | Hofseth Biocare ASA | 120 | 2025-01-20 | 2026-05-14 |
| Effects of UC-II, Glucosamine and Curcumin Supplementation on Knee Pain and Inflammation. UCII, glucosamine and curcumin, Placebo - Inflammation, Knee Pain Chronic | Not applicable | Completed | Taipei Medical University | 32 | 2024-08-20 | 2026-01-07 |
| Efficacy of Bioactive Collagen Peptide Compared to Glucosamine and Chondroitin Sulphate in Grade I-III Knee Osteoarthritis Bioactive Collagen Peptide, Glucosamine and Chondroitin Sulphate - Knee Osteoarthritis (Kellgren-Lawrence Grade 1-3) | Not applicable | Completed | Liaquat National Hospital & Medical College | 150 | 2023-06-01 | 2026-08-10 |
| Efficacy of Topical Glucosamine Versus Corticosteroid in Oral Lichen Planus Glucosamine Hydrochloride, Triamcinolone Acetonide - Oral Lichen Planus | Phase 4 | Completed | Future University in Egypt | 36 | 2023-05-01 | 2025-08-17 |
| Glucosamine Sulphate Versus Ginger in Non-Surgical Periodontal Therapy Glucosamine Sulfate, Ginger Oil - Periodontal Pocket | Phase 2 | Completed | Ain Shams University | 30 | 2022-11-08 | 2024-01-17 |
| Clinical Study to Evaluate the Effect of Different Doses of UC-II® Supplementation on the Range of Motion & Joint Discomfort in Healthy Subjects Collagen type II (40 mg/day), Collagen type II (80mg/day), Collagen type II (120 mg/day) - Joint Pain | Not applicable | Unknown | Vedic Lifesciences Pvt. Ltd. | 375 | 2022-10-10 | 2022-11-30 |
| To Evaluate the Efficacy and Safety of Collavant n2 in Individuals With Osteoarthritis of the Knee Collavant n2 40 mg/day, Glucosamine hydrochloride & Chondroitin sulfate, Microcrystalline cellulose - Osteoarthritis, Knee | Not applicable | Completed | Vedic Lifesciences Pvt. Ltd. | 236 | 2022-08-08 | 2023-09-06 |
| VIAging Deceleration Trial Using Metformin, Dasatinib, Rapamycin and Nutritional Supplements Study Drugs and Nutritional Supplements - Aging | Phase 1 | Withdrawn | Vitality in Aging Research Group, Inc. | 2022-06-01 | 2022-06-07 | |
| Neoadjuvant HAIC of TACE Plus Donafenib in BCLC B Stage HCC: a Multi-center Randomized Controlled Trial. HAIC, TACE, FOLFOX - Hepatocellular Carcinoma | Phase 2 / Phase 3 | Terminated | Peking University | 18 | 2021-12-24 | 2025-12-18 |
| Prescription-grade Crystalline Glucosamine Sulfate Therapy in Erosive Hand Osteoarthritis Glucosamine Sulfate - Erosive Osteoarthritis of the Hand | Completed | University of Siena | 123 | 2021-01-07 | 2022-03-04 | |
| Effects of Creatine Supplementation as Compared to Glucosamine/Chondroitin Sulfate Supplementation in Addition to Exercise and Physical Therapy in the Management of Knee Osteoarthritis. Creatine Supplementation, Glucosamine and Chondroitin sulfate supplementation, Supervised Exercise training - Knee Osteoarthritis | Not applicable | Completed | Foundation University Islamabad | 24 | 2020-06-10 | 2020-12-14 |
| A Parallel-group Active Comparator, Double-blind, Multicenter, Randomized, Double-blind, Phase III Clinical Study glucosamine sulphate 1500mg and meloxicam 15mg, Glucosamine sulfate 1500mg and chondroitin sulfate 1200mg, Placebos - Knee Osteoarthritis | Phase 3 | Withdrawn | Eurofarma Laboratorios S.A. | 2019-01-01 | 2022-04-18 | |
| Crystalline Glucosamine Sulfate Therapy in Hand Osteoarthritis Glucosamine Sulfate - Hand Osteoarthritis | Completed | University of Siena | 108 | 2018-09-01 | 2019-04-12 | |
| Glucosamine and Chondroitin in Gut in Preventing People From Inflammation Glucosamine Sulfate/Chondroitin Sulfate Tablet, Placebo - Healthy Subject | Phase 1 | Completed | Fred Hutchinson Cancer Center | 9 | 2018-05-11 | 2019-05-24 |
| Glucosamine and Chondroitin in Preventing Inflammation in Overweight Patients Glucosamine, Placebo - Healthy Subject, Overweight | Phase 1 | Completed | Fred Hutchinson Cancer Center | 2 | 2017-08-01 | 2019-02-01 |
| Individual Differences in Glucosamine Sulfate Exposure Levels Glucosamine Sulfate - Knee Osteoarthritis | Unknown | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 400 | 2017-07-02 | 2017-07-05 | |
| The Marigot Osteoarthritis Nutritional Intervention (MOANi) Trial Aquamin-Plus, Glucosamine sulphate - Knee Osteoarthritis | Not applicable | Unknown | University College Dublin | 30 | 2017-05-01 | 2017-04-10 |
| Polycan in Combination With Glucosamine for Treatment of Knee Osteoarthritis Glucosamine 1500 mg, Polycan 50mg + Glucosamine 750 mg, Polycan 50mg + Glucosamine 1500 mg - Osteoarthritis of the Knee | Not applicable | Completed | Vietstar Biomedical Research | 90 | 2017-04-01 | 2018-10-24 |
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Osteoarthritis, Knee (20) · Osteoarthritis (13) · Arthralgia (3) · Inflammation (3) · Lichen Planus, Oral (2) · Low Back Pain (2) · Back Pain (1) · Breast Neoplasms (1) · Carcinoma, Hepatocellular (1) · Chronic Pain (1) · Chronic Periodontitis (1) · Diabetes Mellitus (1) · Disease Progression (1) · Insulin Resistance (1) · Motor Activity (1)
Ain Shams University (3) · Eurofarma Laboratorios S.A. (3) · Fred Hutchinson Cancer Center (3) · Vedic Lifesciences Pvt. Ltd. (3) · Azidus Brasil (2) · National Center for Complementary and Integrative Health (NCCIH) (2) · University of Siena (2) · Ache Laboratorios Farmaceuticos S.A. (1) · Ardabil University of Medical Sciences (1) · Bioiberica (1) · Bispebjerg Hospital (1) · Dawn L. Hershman (1) · Ferrosan AS (1) · Foundation University Islamabad (1) · Future University in Egypt (1)
United States (10) · Brazil (4) · Egypt (3) · India (3) · Pakistan (3) · China (2) · Denmark (2) · Iran (2) · Italy (2) · Spain (2) · Taiwan (2) · Australia (1) · Canada (1) · Ireland (1) · Norway (1)
Ahmaed Y Gamal (1) · Ammarin Thakkinstian, Ph.D (1) · C. Kent Kwoh, M.D. (1) · Charles Bridges-Webb, MB, BS (1) · Christie Newton, Dr. (1) · Christopher G. Jackson, MD (1) · Conor McCarthy, MD (1) · Cristiano F. Zerbini, Phd/MD (1) · Dana Grecov, Dr. (1) · Dawn Hershman, MD (1) · Dina A. Othman, professor (1) · Dr Shalini Srivastava, MD medicine (1) · Eamonn Delahunt, PhD (1) · Edio Costa, Doctor (1) · Elizabeth Anne Weinstock (1)
PMID 16495392, PMID 17065354, PMID 17265490, PMID 18821708, PMID 19679221, PMID 20606148, PMID 21807137, PMID 22213129, PMID 22718223, PMID 22900984, PMID 23647688, PMID 24395557, PMID 24616448, PMID 25589511, PMID 25719429, PMID 27729073, PMID 30657100, PMID 31429006, PMID 32444040, PMID 33468249, PMID 34088340, PMID 35637324