8 completed, 2 recruiting, 2 terminated, 2 unknown. 6 Not applicable, 6 Phase 2, 1 Early Phase 1, 1 Phase 1, 1 Phase 3.
Follow Diarylheptanoids: new trials by email Literature Review of Diarylheptanoids trials Research Report on Diarylheptanoids
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Curcumin in Critically Ill Patients With Sepsis Curcumin, Placebo - Sepsis | Not applicable | Recruiting | Hospital Civil de Guadalajara | 56 | 2026-03-01 | 2026-09-17 |
| Safety of Anal Curcumin Curcuminoid Capsules - Anal High Grade Squamous Intraepithelial Lesion | Phase 1 | Recruiting | Lisa Flowers | 48 | 2025-03-17 | 2026-08-18 |
| The Effect of Supplementation with Curcuminoids for the Improvement of Musculoskeletal Conditions in Sedentary Adults Supplement with curcuminoids, Physical excercise - Sedentariness and Well-being | Phase 3 | Completed | Lissette Ariza Corredor | 34 | 2023-07-05 | 2025-01-08 |
| A Clinical Study of Curcuvail® in Patients With Non-alcoholic Fatty Liver Disease Test Product: Curcuvail® 250mg capsule (Curcuma longa Extractcontaining 35% Curcuminoids), Placebo product - Fatty Liver Without Mention of Alcohol | Phase 2 | Completed | COD Research Private Ltd | 30 | 2021-01-08 | 2024-02-13 |
| Turmeric Efficacy for Mobility and Joint Function Turmipure GOLD®, Turmeric rhizome PE 95% curcuminoids, Placebo - Knee Discomfort, Joint Pain | Not applicable | Completed | Givaudan France Naturals | 177 | 2020-09-24 | 2023-05-03 |
| Phase II Trial to Modulate Intermediate Endpoint Biomarkers in Former and Current Smokers Curcumin C3 complex®, Lovaza®, Placebo - Lung Diseases, Lung Cancer, Protection Against | Phase 2 | Active not recruiting | H. Lee Moffitt Cancer Center and Research Institute | 19 | 2019-06-05 | 2026-02-27 |
| Curcuminoids and Contrast-induced Acute Kidney Injury Curcuminoid, Placebo - Acute Kidney Injury, Contrast Media Toxicity | Early Phase 1 | Completed | Bangkok Metropolitan Administration Medical College and Vajira Hospital | 96 | 2018-10-01 | 2021-05-18 |
| Management of Frailty in Older Adults With Turmeric and Tulsi Supplements C. longa, curcuminoids , Z. officianale, O. sanctum along with 200 ml of Milk, Standard of Care - Frail Elderly Syndrome | Not applicable | Unknown | Composite Interceptive Med Science | 50 | 2018-07-01 | 2018-04-11 |
| Efficacy of Curcumin in Oral Submucous Fibrosis 10% Curcumin mucoadhesive gel, Curcumin capsules 500mg, 5% curcumin mucoadhesive gel + Curcumin capsules 250 mg - Oral Submucous Fibrosis | Phase 2 | Unknown | H.K.E.S's S.Nijalingappa Institute of Dental Science and Research | 200 | 2014-01-01 | 2018-04-27 |
| Effects of CUrcuminoids on Coronary Artery byPass graftIng-related myocarDial Infarction Study Curcuminoids, Placebo - Coronary Artery Bypass Grafting | Not applicable | Completed | Wanwarang Wongcharoen, MD. | 200 | 2009-09-01 | 2019-09-18 |
| Effect of Antioxidant Cocktail in Beta-thalassemia/Hb E Patients curcuminoids, N-acetylcysteine, deferiprone and vitamin E, Curcuminoids and alpha-tocopherol - Thalassemia | Not applicable | Completed | Mahidol University | 60 | 2009-06-01 | 2012-05-15 |
| Curcumin for the Prevention of Radiation-induced Dermatitis in Breast Cancer Patients Curcumin C3 Complex, Placebo - Breast Cancer | Phase 2 | Completed | University of Rochester | 35 | 2008-01-01 | 2012-06-25 |
| A Clinical Study of Curcuminoids in the Treatment of Oral Lichen Planus Curcuminoids, Placebo - Oral Lichen Planus | Phase 2 | Completed | Nita Chainani Wu | 20 | 2007-10-01 | 2013-08-07 |
| Curcumin for the Chemoprevention of Colorectal Cancer Curcuminoids - Adenomatous Polyps | Not applicable | Terminated | University of Pennsylvania | 56 | 2005-07-01 | 2017-04-20 |
| A Randomized, Placebo-controlled, Double-blind Clinical Trial of Curcuminoids in Oral Lichen Planus Curcuminoids - Oral Lichen Planus | Phase 2 | Terminated | University of California, San Francisco | 2003-02-01 | 2023-11-08 |
Lichen Planus, Oral (2) · Acute Kidney Injury (1) · Adenomatous Polyps (1) · Arthralgia (1) · Breast Neoplasms (1) · Colorectal Neoplasms (1) · Critical Illness (1) · Inflammation (1) · Lung Diseases (1) · Lung Neoplasms (1) · Myocardial Infarction (1) · Neoplasms (1) · Oral Submucous Fibrosis (1) · Renal Insufficiency, Chronic (1) · Sepsis (1)
Bangkok Metropolitan Administration Medical College and Vajira Hospital (1) · COD Research Private Ltd (1) · Composite Interceptive Med Science (1) · Givaudan France Naturals (1) · H. Lee Moffitt Cancer Center and Research Institute (1) · H.K.E.S's S.Nijalingappa Institute of Dental Science and Research (1) · Hospital Civil de Guadalajara (1) · Lisa Flowers (1) · Lissette Ariza Corredor (1) · Mahidol University (1) · Nita Chainani Wu (1) · University of California, San Francisco (1) · University of Pennsylvania (1) · University of Rochester (1) · Wanwarang Wongcharoen, MD. (1)
United States (6) · India (3) · Thailand (3) · Colombia (1) · Croatia (1) · Mexico (1) · Slovenia (1)
Alice P Pentland, MD (1) · Carmen E Guerra, M.D. (1) · Dr. Alben Sigamani (1) · Dr. Sanjaya Chauhan (1) · Enrique Cervantes-Perez, MD and MSc (1) · Julie L Ryan, PhD, MPH (1) · Lisa Flowers, MD, MPH (1) · Marilyn Ling, MD (1) · Mr. Nimesh Parekh, M.Sc. (1) · Nagi Kumar, Ph.D (1) · Nita Chainani-Wu, DMD, MPH, MS (1) · Nita Chainani-Wu, DMD, MS, PhD (1) · Ruchaneekorn Kalpravidh, Assoc. Prof. Dr. (1)
PMID 11979336, PMID 18155609, PMID 21907450, PMID 23314316, PMID 29130810, PMID 31141635, PMID 31700251, PMID 33081797
5KL2RR024136-03 (1)