49 terminated. 49 Phase 3, 11 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 49 | Terminated 49 |
| Phase 2 | 11 | Terminated 11 |
Follow Ischemia: new trials by email Literature Review of Ischemia trials Research Report on Ischemia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effect of Low-dose Intracoronary Reteplase on Myocardial Infarct Size During Primary Percutaneous Coronary Intervention Normal Saline, Reteplase Injection 9mg, Reteplase Injection 18mg - Acute ST-segment Elevation Myocardial Infarction | Phase 3 | Terminated | Ge Junbo | 36 | 2021-07-01 | 2023-09-14 |
| Comparing Between CO2 and Phenylephrine Treatment in Patients With Progressive Lacunar Infarction (CARBOGEN Study) carbogen, phenylephrine - Acute Ischemic Stroke | Phase 3 | Terminated | Yonsei University | 3 | 2021-04-05 | 2025-01-14 |
| COLchicine to Prevent Sympathetic Denervation After an Acute Myocardial Infarction Colchicine - Myocardial Infarction, Acute | Phase 2 / Phase 3 | Terminated | University Hospital, Montpellier | 54 | 2020-12-04 | 2026-06-12 |
| Phase 3 Study to Evaluate the Efficacy and Safety of Intravenous BIIB093 (Glibenclamide) for Severe Cerebral Edema Following Large Hemispheric Infarction BIIB093, Placebo - Brain Edema, Stroke, Acute | Phase 3 | Terminated | Remedy Pharmaceuticals, Inc. | 535 | 2018-08-29 | 2024-11-25 |
| Effect of Methotrexate Carried by a Lipid Nanoemulsion on Left Ventricular Remodeling After STEMI Methotrexate, Placebo, Folic Acid - Myocardial Infarction, Anterior Wall, Myocardial Remodeling, Ventricular | Phase 2 / Phase 3 | Terminated | University of Sao Paulo | 35 | 2018-04-17 | 2021-01-11 |
| The Efficacy and Safety of REX-001 to Treat Ischemic Ulcers in Subjects With CLI Rutherford Category 5 and DM REX-001, Placebo - Peripheral Arterial Disease (PAD), Diabetes Mellitus (DM) | Phase 3 | Terminated | Ixaka Ltd | 49 | 2017-04-25 | 2023-03-16 |
| The Efficacy and Safety of REX-001 to Treat Ischemic Rest Pain in Subjects With CLI Rutherford Category 4 and DM REX-001, Placebo - Peripheral Arterial Disease (PAD), Diabetes Mellitus (DM) | Phase 3 | Terminated | Ixaka Ltd | 3 | 2017-04-05 | 2021-05-07 |
| Effect of DLBS1033 After Primary PCI in Patients With STE-ACS DLBS1033, Placebo, Standard therapy - ST Elevation Myocardial Infarction | Phase 2 / Phase 3 | Terminated | Dexa Medica Group | 23 | 2016-11-01 | 2023-09-08 |
| Bivalirudin Infusion for Ventricular Infarction Limitation PPCI, Bivalirudin, Heparin - Acute Myocardial Infarction | Phase 3 | Terminated | The Medicines Company | 78 | 2014-12-19 | 2018-10-05 |
| Efficacy and Safety of AMG0001 in Subjects With Critical Limb Ischemia HGF Plasmid (AMG0001), Matching Placebo - Critical Limb Ischemia | Phase 3 | Terminated | AnGes USA, Inc. | 46 | 2014-11-12 | 2019-08-13 |
| Multi-cap for Increase Adherence After Acute Myocardial Infarction Combined capsule, Conventional therapy - Myocardial Infarction | Phase 3 | Terminated | Hospital El Cruce | 100 | 2014-04-01 | 2017-01-11 |
| Prasugrel and Ticagrelor in ST-segment Elevation Myocardial Infarction Prasugrel 60 mg, Ticagrelor 180 mg - ST-Segment Elevation Myocardial Infarction | Phase 3 | Terminated | Dong-A University | 39 | 2014-01-01 | 2017-08-18 |
| The Evaluation of Bococizumab (PF-04950615; RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects bococizumab (PF-04950615), Placebo - Cardiovascular Disease | Phase 3 | Terminated | Pfizer | 10564 | 2013-10-29 | 2019-05-01 |
| The Evaluation of Bococizumab (PF-04950615;RN316) in Reducing the Occurrence of Major Cardiovascular Events in High Risk Subjects bococizumab (PF-04950615), Placebo - Cardiovascular Disease | Phase 3 | Terminated | Pfizer | 16784 | 2013-10-29 | 2018-07-11 |
| Stentys Coronary Stent System Clinical Trial in Patients With Acute Myocardial Infarction STENTYS self-apposing stent, VISION balloon-expandable stent - Acute Myocardial Infarction | Phase 3 | Terminated | Stentys | 318 | 2013-05-01 | 2017-04-20 |
| Renal Graft Function After Treatment With Erythropoietin (EPO) beta-epoietin - Ischemia | Phase 3 | Terminated | University Hospital, Limoges | 6 | 2011-12-01 | 2016-09-05 |
| Safety and Efficacy Study of Urokinase for the Treatment of Diabetic Foot Syndrome and Critical Limb Ischemia urokinase - Diabetic Foot, Critical Limb Ischemia | Phase 3 | Terminated | GWT-TUD GmbH | 34 | 2011-06-01 | 2014-04-07 |
| A Multinational Trial To Evaluate The Parachute Implant System Parachute Implant - Heart Failure, Myocardial Infarction | Phase 3 | Terminated | CardioKinetix, Inc | 59 | 2011-05-01 | 2017-06-23 |
| Induced Hypertension for Treatment of Delayed Cerebral Ischaemia After Aneurysmal Subarachnoid Haemorrhage Induced hypertension - Cerebral Ischemia, Subarachnoid Hemorrhage | Phase 3 | Terminated | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 26 | 2010-08-01 | 2017-11-06 |
| The Effects of Very Early Use of Rosuvastatin in Preventing Recurrence of Ischemic Stroke Rosuvastatin, Placebo tablet - Stroke | Phase 3 | Terminated | Severance Hospital | 318 | 2010-08-01 | 2014-11-20 |
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Myocardial Infarction (20) · Stroke (14) · Cardiovascular Diseases (10) · ST Elevation Myocardial Infarction (9) · Chronic Limb-Threatening Ischemia (6) · Brain Ischemia (5) · Cerebral Infarction (5) · Myocardial Ischemia (5) · Acute Coronary Syndrome (4) · Atherosclerosis (4) · Cerebrovascular Disorders (4) · Diabetes Mellitus (4) · Brain Infarction (3) · Heart Diseases (3)
Pathologic Processes (49) · Pathological Conditions, Signs and Symptoms (49) · Vascular Diseases (43) · Cardiovascular Diseases (36) · Necrosis (36) · Infarction (35) · Heart Diseases (25) · Myocardial Ischemia (23) · Nervous System Diseases (18) · Central Nervous System Diseases (17) · Brain Diseases (16) · Cerebrovascular Disorders (14) · Arterial Occlusive Diseases (12) · Arteriosclerosis (12)
Aspirin (3) · Ancrod (2) · Clopidogrel (2) · Injections (2) · Saline Solution (2) · Standard of Care (2) · Urokinase-Type Plasminogen Activator (2) · bococizumab (2) · treprostinil (2) · Cerebral Revascularization (1) · Colchicine (1) · Cool-Down Exercise (1) · Cytidine Diphosphate Choline (1) · DLBS 1033 (1) · Embolectomy (1)
Ixaka Ltd (2) · Merck Sharp & Dohme LLC (2) · Neurobiological Technologies (2) · Pfizer (2) · The Medicines Company (2) · United Therapeutics (2) · Abiomed Inc. (1) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · AnGes USA, Inc. (1) · Arginox Pharmaceuticals (1) · Axio Research. LLC (1) · CardioKinetix, Inc (1) · Cogentus Pharmaceuticals (1) · Dexa Medica Group (1) · Dong-A University (1)
United States (23) · Germany (13) · Netherlands (11) · France (10) · Canada (9) · Czechia (9) · Poland (9) · Hungary (8) · Spain (8) · United Kingdom (8) · Australia (7) · Brazil (7) · Israel (7) · South Korea (7) · Switzerland (7)
Deepak L. Bhatt, MD (2) · Gilbert Wagener, MD (2) · Warren Wasiewski, M.D. (2) · Aline G. Ferrari, MD (1) · Andrew P Levy, MD PhD (1) · Arjen Slooter, MD, PhD (1) · Carlos Tajer, MD (1) · Chen Shapira, MD (1) · Dariusz Dudek, MD, PhD (1) · Eric Topol, MD (1) · Friedhelm Beyersdorf, Prof. Dr. (1) · Gustav Steinhoff, M.D. (1) · Hans F Dohmann, MD (1)
PMID 28304242, PMID 29685591, PMID 29716940, PMID 35277540, PMID 17387132, PMID 18032779, PMID 19699853, PMID 19915221, PMID 20709233, PMID 20925534, PMID 20976246, PMID 22068990, PMID 22077816, PMID 22085343, PMID 22305835, PMID 22691567, PMID 22747980, PMID 22782417, PMID 23101451, PMID 23537969, PMID 23686372, PMID 23692645, PMID 23881958, PMID 23916935, PMID 23973688, PMID 24152824, PMID 24211500, PMID 24402559, PMID 25012288, PMID 25037310, PMID 25129064, PMID 25218533, PMID 25440792, PMID 25959558, PMID 26025218, PMID 26089177, PMID 26443829, PMID 26708287, PMID 27012778, PMID 27151345, PMID 27162212, PMID 27502866, PMID 27834742, PMID 27902833, PMID 28382371, PMID 28781130, PMID 28988157, PMID 29158449, PMID 29627296, PMID 29632238
2005 (1), 2009 (1), 2014 (1), 2017 (1), P50NS044148 (1), P50NS044227 (1), U01HL081616 (1), U01HL081649 (1)