7 recruiting, 6 completed, 5 unknown, 4 not yet recruiting. 26 Phase 3, 5 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 26 | Recruiting 7, Completed 6, Unknown 5, Not yet recruiting 4, Terminated 3, Active not recruiting 1 |
| Phase 2 | 5 | Completed 3, Not yet recruiting 1, Unknown 1 |
Follow Intracerebral Hemorrhage: new trials by email Literature Review of Intracerebral Hemorrhage trials Research Report on Intracerebral Hemorrhage
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| APEX-STROKE CALM-ICH Domain Angong Niuhuang Pills (ANP), Placebo - Stroke, Intracerebral Hemorrhage | Phase 3 | Not yet recruiting | Fudan University | 1100 | 2026-10-01 | 2026-08-26 |
| Huayu Jiedu Formula (FTFY-919) Granules Versus Traditional Decoction for Acute Hypertensive Intracerebral Hemorrhage Huayu Jiedu Formula (FTFY-919) Granules, Huayu Jiedu Formula (FTFY-919) Traditional Decoction, Placebo Granules - Intracerebral Hemorrhage, Hypertension | Phase 3 | Not yet recruiting | Guangzhou University of Traditional Chinese Medicine | 300 | 2026-09-01 | 2026-09-03 |
| Efficacy and Safety of Minocycline in Acute Spontaneous Intracerebral Hemorrhage Minocycline hydrochloride capsules, Placebo capsules of Minocycline hydrochloride capsules - Intracerebral Hemorrhage | Phase 3 | Recruiting | Beijing Tiantan Hospital | 1192 | 2026-04-02 | 2026-04-23 |
| Synergistic Minimally Invasive Surgery and Deferoxamine in ICH Minimally Invasive surgery (MIS), Deferoxamine, Standard Medical Care (SMD) - Intracerebral Hemorrhage, ICH - Intracerebral Hemorrhage | Phase 2 / Phase 3 | Not yet recruiting | University of Illinois at Chicago | 240 | 2026-03-01 | 2025-10-10 |
| Reduction of Edema With a Specialized Cocktail for Ultra-early Management in Intracerebral Hemorrhage PPA Intervention - Intracerebral Hemorrhage | Phase 3 | Not yet recruiting | Second Affiliated Hospital, Zhejiang University, School of Medicine | 58 | 2025-05-08 | 2025-05-14 |
| Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2 Recombinant Factor VIIa, Biological/Vaccine: Placebo - Intracerebral Hemorrhage | Phase 3 | Recruiting | Joseph Broderick, MD | 350 | 2025-05-06 | 2026-08-20 |
| The Fifth INTEnsive pReventing Secondary Injury in Acute Cerebral Haemorrhage Trial Within ACT-GLOBAL Colchicine 0.5 mg, Deferoxamine Mesylate, Control (Standard treatment) - Intracerebral Hemorrhage, Spontaneous Intracerebral Hemorrhage | Phase 3 | Recruiting | The George Institute | 2000 | 2025-02-27 | 2026-07-08 |
| PROpranolol for Cerebral Hemorrhage-ASsociated pnEumonia (PRO-CHASE) Propranolol Hydrochloride, control group - Stroke, Vascular Accident | Phase 2 / Phase 3 | Completed | Beijing Tiantan Hospital | 168 | 2023-02-21 | 2025-07-14 |
| Stroke Prophylaxis With Apixaban in Chronic Kidney Disease Stage 5 Patients With Atrial Fibrillation Apixaban 2.5 milligram Oral Tablet - Chronic Kidney Diseases, Atrial Fibrillation | Phase 3 | Recruiting | Region Stockholm | 1400 | 2023-02-17 | 2024-10-04 |
| Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial Recombinant Activated Factor VII (rFVIIa), Placebo - Intracerebral Hemorrhage | Phase 3 | Active not recruiting | Joseph Broderick, MD | 860 | 2021-12-03 | 2026-01-21 |
| Chinese Herbal Medicine in Acute INtracerebral Haemorrhage (CHAIN) Trial Chinese herbal medicine FYTF-919 - Intracerebral Hemorrhage | Phase 3 | Unknown | Guangzhou University of Traditional Chinese Medicine | 1504 | 2021-10-01 | 2021-10-04 |
| Antiplatelet Secondary Prevention International Randomised Trial After INtracerebral HaemorrhaGe (ASPIRING)-Pilot Phase Start antiplatelet monotherapy - Intracerebral Hemorrhage | Phase 3 | Completed | The George Institute for Global Health, China | 80 | 2021-09-03 | 2025-03-26 |
| Statin for Neuroprotection in Spontaneous Intracerebral Hemorrhage Statin - Intracerebral Hemorrhage, Statins | Phase 2 / Phase 3 | Unknown | Capital Medical University | 98 | 2021-08-06 | 2024-01-23 |
| Remote Ischemic Conditioning for the Treatment of Intracerebral Hemorrhage Remote ischemic conditioning, Sham remote ischemic conditioning, Standard medication therapy - Intracerebral Hemorrhage, Acute Stroke | Phase 3 | Unknown | Capital Medical University | 452 | 2021-04-22 | 2022-07-19 |
| MRI-visible Enlarged Perivascular Spaces and the Alteration of Lymphatic Drainage System in CAA 1. amyloid PET；2. T807 PET - Cerebral Amyloid Angiopathy, Intracerebral Hemorrhage | Phase 3 | Unknown | National Taiwan University Hospital | 120 | 2020-10-08 | 2020-10-27 |
| Statins In Intracerbral Hemorrhage Statins - Intracerebral Hemorrhage | Phase 3 | Recruiting | Beth Israel Deaconess Medical Center | 1456 | 2020-06-10 | 2026-04-21 |
| Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT) Cognitive Sub-Study telmisartan 20mg + amlodipine 2.5mg +indapamide 1.25mg, Placebo oral capsule - Cognitive Decline, Intracerebral Hemorrhage | Phase 3 | Terminated | The George Institute | 1 | 2020-02-27 | 2021-04-01 |
| Anticoagulation in ICH Survivors for Stroke Prevention and Recovery Apixaban, Aspirin - Intracerebral Hemorrhage, Atrial Fibrillation | Phase 3 | Recruiting | Yale University | 700 | 2020-01-28 | 2026-05-08 |
| PREvention of STroke in Intracerebral haemorrhaGE Survivors With Atrial Fibrillation Apixaban Oral Tablet, Dabigatran, Edoxaban Tablets - Atrial Fibrillation, Intracerebral Hemorrhage | Phase 3 | Completed | Imperial College London | 319 | 2019-06-03 | 2025-01-13 |
| Avoiding Anticoagulation After IntraCerebral Haemorrhage Apixaban 5 MG, left atrial appendage closure - Intracerebral Hemorrhage, Atrial Fibrillation | Phase 3 | Recruiting | University Hospital, Lille | 300 | 2019-01-17 | 2026-04-07 |
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Cerebral Hemorrhage (26) · Stroke (7) · Atrial Fibrillation (4) · Intracranial Hemorrhages (3) · Hemorrhagic Stroke (2) · Hypertension (2) · Arrhythmias, Cardiac (1) · Basal Ganglia Hemorrhage (1) · Cardiovascular Diseases (1) · Cerebral Amyloid Angiopathy (1) · Cerebral Small Vessel Diseases (1) · Cerebrovascular Disorders (1) · Cognitive Dysfunction (1) · Death (1) · Dementia, Vascular (1)
Brain Diseases (26) · Central Nervous System Diseases (26) · Hemorrhage (26) · Nervous System Diseases (26) · Pathologic Processes (26) · Pathological Conditions, Signs and Symptoms (26) · Vascular Diseases (26) · Cardiovascular Diseases (25) · Cerebrovascular Disorders (25) · Intracranial Hemorrhages (23) · Heart Diseases (4) · Arrhythmias, Cardiac (3) · Intracranial Arterial Diseases (2) · Amyloidosis (1) · Arterial Occlusive Diseases (1)
apixaban (3) · Deferoxamine (2) · Hydroxymethylglutaryl-CoA Reductase Inhibitors (2) · recombinant FVIIa (2) · 3-hydroxy-3-methylglutaryl-coenzyme A (1) · Amlodipine (1) · Aspirin (1) · Biological Products (1) · Colchicine (1) · Control Groups (1) · Dabigatran (1) · Fluoxetine (1) · Indapamide (1) · Left Atrial Appendage Closure (1) · Minimally Invasive Surgical Procedures (1)
Beijing Tiantan Hospital (2) · Capital Medical University (2) · Guangzhou University of Traditional Chinese Medicine (2) · Joseph Broderick, MD (2) · The George Institute (2) · Beth Israel Deaconess Medical Center (1) · Fudan University (1) · Imperial College London (1) · Johns Hopkins University (1) · National Taiwan University Hospital (1) · Region Stockholm (1) · Rong Hu, MD (1) · Second Affiliated Hospital, Zhejiang University, School of Medicine (1) · The George Institute for Global Health, China (1) · Universidad Autónoma de Aguascalientes (1)
China (10) · United States (7) · Germany (6) · Canada (4) · Spain (4) · United Kingdom (4) · Australia (3) · Japan (3) · France (2) · Taiwan (2) · Austria (1) · Finland (1) · Hungary (1) · Iceland (1) · Israel (1)
Adnan I Qureshi, MD (1) · Angel A Arauz, PhD (1) · Charlotte Cordonnier, MD, PhD (1) · Craig Anderson, MD (1) · Craig S Anderson (1) · Daniel F. Hanley, MD (1) · Dimitre Staykov, MD (1) · Graeme Hankey, MD (1) · Gursant S. Atwal, MD (1) · Hagen Huttner, MD (1) · Hooman Kamel, MD (1) · Issam Awad, MD (1) · Javed Iqbal, MBBS (1) · Jianwen Guo, MD (1) · Joseph Broderick, MD (1)
PMID 36700520, PMID 34022170, PMID 34937780, PMID 37870112, PMID 10557349, PMID 11880505, PMID 15760647, PMID 16033424, PMID 17909152, PMID 21169826, PMID 22943144, PMID 22989898, PMID 23085382, PMID 23230457, PMID 23647568, PMID 25003359, PMID 26396030, PMID 27276234, PMID 27888608, PMID 28275199, PMID 28628707, PMID 28701501, PMID 28887388, PMID 28929560, PMID 29710119, PMID 29789395, PMID 30319113, PMID 30418098, PMID 30421455, PMID 30739747, PMID 30938800, PMID 31896491, PMID 31919518, PMID 32585668, PMID 32623977, PMID 32838673, PMID 33212054, PMID 33219136, PMID 34010223, PMID 34022160, PMID 34144995, PMID 34210824, PMID 34292474, PMID 34387101, PMID 34427473, PMID 34487721, PMID 34838196, PMID 34844422, PMID 35022304, PMID 35400202
U01NS110772 (2), 2017 (1), 2018 (1), 2019 (1), U01NS056975 (1), U01NS059041 (1), U01NS061861 (1), U01NS062091 (1), U01NS080824 (1), U01NS106513 (1)