45 completed, 28 unknown, 21 recruiting, 8 terminated. 23 Phase 1, 21 Not applicable, 18 Phase 2, 7 Phase 3, 3 Phase 4.
Follow Biological Products: new trials by email Literature Review of Biological Products trials Research Report on Biological Products
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Long-term Medical Impact of War Injuries on Military Personnel biological and radiological examinations - War Injury, Physical Injury | Not applicable | Not yet recruiting | Direction Centrale du Service de Santé des Armées | 20 | 2026-10-01 | 2026-08-14 |
| Probiotic Intervention for Digestive Health in Obese Patients Initiating GLP-RA Treatment Probiotics (Natural product), Placebo - Obesity &Amp; Overweight, Digestive Disorders | Not applicable | Recruiting | Hospices Civils de Lyon | 50 | 2026-08-05 | 2026-08-19 |
| Tumor-Specific T-Cells (cCTL:GL01) for Advanced Gastrointestinal Cancer Biological/Vaccine - Advanced Gastrointestinal Cancer | Phase 1 | Not yet recruiting | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 20 | 2026-08-01 | 2026-07-29 |
| A Study of Clinical and Immune Responses to Sequential Biologic Therapies in Psoriatic Arthritis Biologic or targeted synthetic DMARD (b/tsDMARD) - Psoriasis Arthritis | Not yet recruiting | Royal United Hospitals Bath NHS Foundation Trust | 400 | 2026-06-01 | 2026-05-13 | |
| Safety, Tolerability and Preliminary Efficacy of NEUK203-13 in Refractory Neuroendocrine Tumor Patients Biological/Vaccine: NK Cell Therapy Product Derived from Induced Pluripotent Stem Cells (iPSCs) Engineered with Anti-DLL3 CAR Construct, Followed by Differentiation and Expansion - SCLC, Extensive Stage, Neuroendocrine Tumors | Phase 1 | Recruiting | Cancer Institute and Hospital, Chinese Academy of Medical Sciences | 9 | 2026-02-20 | 2026-06-25 |
| Study of an RSV-hMPV-PIV3 Trivalent Vaccine Candidate VXB-251 in Older Adults trivalent (RSV/hMPV/PIV3) vaccine candidate, bivalent (RSV/hMPV) unlicensed comparator, monovalent (RSV) unlicensed comparator - Lower Respiratory Tract Disease, Healthy Participants | Phase 1 | Active not recruiting | Sanofi | 240 | 2025-11-17 | 2026-05-20 |
| Pain in Inflammatory Joint Diseases Biological or targeted synthetic DMARD - Arthritis, Arthritis, Juvenile Idiopathic | Recruiting | Diakonhjemmet Hospital | 350 | 2025-11-11 | 2026-04-13 | |
| Multi-modular Chimeric Antigen Receptor T Cells tarGeting B7-H3 in Children, Teenage & Young Adult Sarcoma Biological/Vaccine: hBRCA84D CAR T cells - Sarcoma | Phase 1 | Recruiting | University College, London | 12 | 2025-07-23 | 2026-08-07 |
| Recombinant Factor VIIa (rFVIIa) for Hemorrhagic Stroke Trial - Part 2 Recombinant Factor VIIa, Biological/Vaccine: Placebo - Intracerebral Hemorrhage | Phase 3 | Recruiting | Joseph Broderick, MD | 350 | 2025-05-06 | 2026-08-20 |
| Articular Damage in Patients With Juvenile Idiopathic Arthritis After Transition to Adult Care Methotrexate, Biological Drug - Juvenile Chronic Arthritis | Not yet recruiting | IRCCS Burlo Garofolo | 100 | 2025-04-01 | 2025-03-26 | |
| An Efficacy, Safety, and Tolerability Study of VX-880 in Participants With Type 1 Diabetes With a Kidney Transplant Biological/Vaccine - Type 1 Diabetes, Kidney Transplant | Phase 3 | Recruiting | Vertex Pharmaceuticals Incorporated | 10 | 2025-03-31 | 2026-03-23 |
| International Severe CRSwNP Registry 2024-2028 Biologic drugs - Chronic Rhinosinusitis With Nasal Polyps (CRSwNP) | Active not recruiting | Vibeke Backer | 3000 | 2025-03-31 | 2025-04-08 | |
| Impact of IIT-SIT on Dengue Clusters Biological (Male Wolbachia-infected Aedes aegypti) - Dengue | Not applicable | Recruiting | National Environment Agency, Singapore | 900 | 2025-03-20 | 2025-03-25 |
| Follow-up of Spanish Prospective Asthma and Nasal Polyposis Registry Antiasthmatic - Chronic Asthma | Recruiting | Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz | 1200 | 2025-02-01 | 2026-03-30 | |
| Inaticabtagene Autoleucel (Inati-cel; CNCT19) Treatment for Newly Diagnosed B-cell ALL Patients in CR1 Biological: single dose of Inaticabtagene autoleucel - Acute Lymphoblastic Leukemia, B Cell ALL | Phase 2 | Not yet recruiting | First Affiliated Hospital of Zhejiang University | 20 | 2025-01-15 | 2025-01-15 |
| Medico-economic Evaluation of Robot-assisted Laparoscopy Compared With Conventional Laparoscopy in Hysterectomy for Endometrial Cancer. Robot-assisted laparoscopy, conventional laparoscopy, Prospective cohort study - Hysterectomies for Low- or Intermediate-risk Endometrial Carcinoma | Not applicable | Recruiting | Rennes University Hospital | 1680 | 2024-09-23 | 2025-09-15 |
| Clinico-biological Collection of Bone, Calcium and Growth Plate Pathologies Biological samples, Biological - Bone Disorder | Recruiting | University Hospital, Toulouse | 350 | 2024-09-16 | 2026-06-05 | |
| A Randomized, Double-Blind, Placebo-Controlled, Multi-Centre Study to Assess the Efficacy of PURETHAL Mites Mixture 50,000 AUeq/mL Subcutaneous Immunotherapy in Adult Subjects With Moderate to Severe Allergic Rhinitis/Rhinoconjunctivitis With or Without Asthma Induced by House Dust Mite (HDM) PURETHAL Mites 50,000 AUeq/ml, Biological/Vaccine: Placebo - House Dust Mite Allergy, House Dust Mite Rhinitis | Phase 3 | Completed | HAL Allergy | 691 | 2024-09-09 | 2026-08-10 |
| Hematopoietic Stem Cell Transplantation Gene Therapy for Treatment of Severe Hemophilia A Gene therapy, Biological - Hemophilia A | Phase 1 | Not yet recruiting | Expression Therapeutics, LLC | 7 | 2024-09-01 | 2024-02-20 |
| A Study of KYV-101, a CD19 CAR T Cell Therapy, in Participants With Treatment Refractory Progressive Multiple Sclerosis KYV-101 (Biological) - 0.33 ×10^8 cells, KYV-101 (Biological) - 1 ×10^8 cells, Chemotherapy: cyclophosphamide (CYC) - Progressive Multiple Sclerosis | Phase 1 | Active not recruiting | Bruce Cree | 10 | 2024-06-20 | 2026-08-10 |
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Arthritis, Rheumatoid (9) · Asthma (7) · COVID-19 (5) · Crohn Disease (4) · Obesity (4) · Parkinson Disease (4) · Dengue (3) · Pain (3) · Alzheimer Disease (2) · Arthritis, Juvenile (2) · Arthritis, Psoriatic (2) · Breast Neoplasms (2) · Carcinoma, Non-Small-Cell Lung (2) · Carcinoma, Renal Cell (2) · Colitis, Ulcerative (2)
Assistance Publique - Hôpitaux de Paris (5) · Aristotle University Of Thessaloniki (3) · Cairo University (3) · Hospices Civils de Lyon (3) · Assiut University (2) · Immune Cell, Inc. (2) · Institut National de la Santé Et de la Recherche Médicale, France (2) · Memorial Sloan Kettering Cancer Center (2) · National Environment Agency, Singapore (2) · Pfizer (2) · University Hospital, Bordeaux (2) · University Hospital, Lille (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Aibin Liang，MD，Ph.D. (1) · Anchiano Therapeutics Israel Ltd. (1)
France (23) · United States (22) · China (16) · United Kingdom (8) · Spain (7) · Denmark (5) · Germany (5) · Japan (5) · Canada (4) · Egypt (4) · Australia (3) · Greece (3) · Italy (3) · Mexico (3) · Poland (3)
Aibin Liang (1) · Alaa El-Hussuna (1) · Alain Verloes, MD (1) · Alexander B Dagum, MD (1) · Andrew Gumley, PhD (1) · Anthony Oliva, PhD (1) · Bertrand Cariou, MD (1) · Breanna Willeford, DO (1) · Bruce Cree, MD, PhD, MAS (1) · Carmen G Torres, MD (1) · Catherine Arnold, MD (1) · Celeste Lebbe, MD, PhD (1) · Chang-Keun Lee, MD (1)
PMID 31798645, PMID 30876830, PMID 31362741, PMID 12045120, PMID 12493340, PMID 21037369, PMID 21652026, PMID 21840602, PMID 21861971, PMID 22247489, PMID 22409563, PMID 23163490, PMID 23782773, PMID 23920044, PMID 25115882, PMID 25831962, PMID 26501236, PMID 26654720, PMID 26677772, PMID 26798977, PMID 27239557, PMID 27820746, PMID 28433687, PMID 28461289, PMID 28477440, PMID 28583260, PMID 28814336, PMID 29221581, PMID 29290515, PMID 29453280, PMID 29512481, PMID 29567784, PMID 30040124, PMID 30050964, PMID 30390672, PMID 30446575, PMID 31143187, PMID 31365335, PMID 31481566, PMID 31734899, PMID 32032671, PMID 32077450, PMID 32101904, PMID 32128424, PMID 32696266, PMID 32918964, PMID 33045398, PMID 33357481, PMID 33609771, PMID 33900052
2018 (1), 2019 (1), 2023 (1), U01NS110772 (1), U10EY014660 (1)