37 completed, 7 terminated, 6 unknown, 3 recruiting. 57 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 57 | Completed 37, Terminated 7, Unknown 6, Recruiting 3, Not yet recruiting 2, Active not recruiting 1, Withdrawn 1 |
Follow Intraabdominal Infections: new trials by email Literature Review of Intraabdominal Infections trials Research Report on Intraabdominal Infections
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Povidone-iodine Irrigation for Prevention of Intra-abdominal Abscess in Pediatric Perforated Appendicitis: a Multi-center Stepped Wedge Cluster Randomized Study Irrigation with PVI, Usual care - Acute, Perforated Appendicitis | Phase 4 | Not yet recruiting | The University of Texas Health Science Center, Houston | 1750 | 2027-03-01 | 2025-02-10 |
| Intraperitoneal Hydrocortisone for Postoperative Pain and CRP Following Caesarean Section hydrocortisone, Nornal Saline - Postoperative Pain, Caesarean Section | Phase 4 | Completed | Raditsya Mada Gautama, MD | 50 | 2026-06-25 | 2026-10-23 |
| Low-dose Norepinephrine Infusion for Prevention of Post-induction Hypotension in Emergency Surgery for Peritonitis Norepinephrine (0.05 μg/kg/min), Placebo - Secondary Peritonitis, Post-induction Hypotension | Phase 4 | Not yet recruiting | Bach Mai Hospital | 60 | 2026-04-01 | 2026-04-14 |
| Gelaspan vs Crystalloid Therapy in Sepsis Balanced Gelatin Solution, Acetate Ringer's Solution - Sepsis, Intra-Abdominal Infections | Phase 4 | Recruiting | Shanghai Zhongshan Hospital | 318 | 2026-02-13 | 2026-03-20 |
| APPI-Cost Trial for Perforated Appendicitis PVI, Usual Care - Perforated Appendicitis | Phase 4 | Recruiting | The University of Texas Health Science Center, Houston | 346 | 2025-04-07 | 2025-12-11 |
| Magnesium Sulfate in Children Undergoing Laparoscopic Appendectomy Intravenous magnesium sulfate, Normal saline infusion - Opioid Consumption, Multimodal Analgesia | Phase 4 | Recruiting | Medical University of Warsaw | 188 | 2024-09-09 | 2026-08-20 |
| Sugammadex vs Neostigmine Reversal in Pediatric Appendectomy Sugammadex, Neostigmine/Glycopyrrolate - Appendicitis, Surgery | Phase 4 | Terminated | Emory University | 22 | 2023-07-19 | 2025-09-30 |
| Oral Vitamin D Supplementation Prevent Peritoneal Dialysis-related Peritonitis Cholecalciferol, Placebo - Peritoneal Dialysis-associated Peritonitis, Vitamin D Deficiency | Phase 4 | Unknown | Peking University First Hospital | 176 | 2023-06-15 | 2024-08-06 |
| Complex And Simple Appendicitis: REstrictive or Liberal Post-operative Antibiotic eXposure - UCSF Multiple standard of care antibiotics for appendicitis, at physicians' discretion - Appendicitis | Phase 4 | Terminated | University of California, San Francisco | 42 | 2023-06-06 | 2026-10-27 |
| A Study of Levornidazole Disodium Phosphate for Injection vs. Ornidazole in Treatment of Postoperative Intra-Abdominal Infections Caused by Anaerobic Bacteria Levornidazole Disodium Phosphate for Injection, Ornidazole and Sodium Chloride Injection - Intraabdominal Infections | Phase 4 | Completed | Yangtze River Pharmaceutical Group Jiangsu Zilong Pharmaceutical Co. Ltd | 696 | 2023-05-10 | 2025-02-18 |
| The PASTDUe Nutrition Ecosystem Project (PASTDUe) Nutrition Ecosystem pathway, Comparator - Diet, Healthy, Food | Phase 4 | Active not recruiting | Duke University | 300 | 2022-04-25 | 2026-04-23 |
| Lidocaine VS Hemodynamic, Metabolic and Hormonal Response Intravenous lidocaine, Normal saline infusion - Hemodynamic Response, Acute Appendicitis | Phase 4 | Completed | Medical University of Warsaw | 132 | 2022-03-12 | 2023-10-31 |
| Efficacy and Safety of CAZ-AVI in the Treatment of Infections Due to Carbapenem-resistant G- Pathogens in Chinese Adults Zavicefta, Ceftazidime-Avibactam, Best Available Treatment - Urinary Tract Infection, Acute Pyelonephritis | Phase 4 | Completed | Pfizer | 60 | 2021-08-26 | 2024-10-21 |
| Role of Delay and Antibiotics on Perforation Rate While Waiting Appendectomy Antibiotics, cefuroxime and metronidazole, No antibiotics, urgent schedule - Appendicitis | Phase 4 | Completed | Helsinki University Central Hospital | 1800 | 2020-05-18 | 2023-07-11 |
| Antibiotic Duration in Post-appendectomy Abscess ampicillin/clavulanate - Complicated Appendicitis, Perforated Appendicitis | Phase 4 | Terminated | Phoenix Children's Hospital | 7 | 2019-05-01 | 2024-03-08 |
| Intravenous Lidocaine in Children Undergoing Laparoscopic Appendectomy Lidocaine - Acute Appendicitis, Postoperative Pain | Phase 4 | Completed | Medical University of Warsaw | 74 | 2019-03-22 | 2020-05-19 |
| Once Daily Metronidazole for Perforated Appendicitis Metronidazole - Appendicitis | Phase 4 | Withdrawn | Ahmed Nasr | 2019-01-01 | 2017-07-21 | |
| COMPARISON OF TRANSVERSUS ABDOMINIS PLANE BLOCK, LOCAL ANESTHETIC INJECTION TO THE PORT SITES AND INTRAPERITONEAL LOCAL ANESTHESIA APPLICATIONS IN POSTOPERATIVE PAIN MANAGEMENT IN PATIENTS WITH LAPAROSCOPIC APPENDECTOMY Bupivacaine - Postoperative Pain | Phase 4 | Completed | Fatih Sultan Mehmet Training and Research Hospital | 3 | 2018-11-01 | 2021-03-23 |
| Acute Appendicitis: Active Observation With and Without Antibiotics Antibiotic treatment (Piperacillin/Tazobactam, 4 gram x 3), followed by 8-10 days of out-hospital oral antibiotic treatment (Ciprofloxacin 500 mgx2,Flagyl 400 mgx3)., Active observation - Appendicitis | Phase 4 | Completed | Göteborg University | 126 | 2018-05-15 | 2022-08-16 |
| Wound Infiltration With Local Anesthetic Agent for Laparoscopic Appendectomy in Adult Bupivacaine - Appendicitis Acute | Phase 4 | Completed | National Taiwan University Hospital | 47 | 2018-04-23 | 2020-04-27 |
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Appendicitis (31) · Peritonitis (17) · Kidney Failure, Chronic (5) · Pain, Postoperative (4) · Infections (3) · Pneumonia, Ventilator-Associated (3) · Sepsis (3) · Urinary Tract Infections (3) · Abdominal Abscess (2) · Bacterial Infections (2) · Cholecystitis (2) · Cross Infection (2) · Diverticulitis (2) · Healthcare-Associated Pneumonia (2)
Infections (54) · Digestive System Diseases (46) · Cecal Diseases (31) · Gastroenteritis (31) · Gastrointestinal Diseases (31) · Intestinal Diseases (31) · Pathological Conditions, Signs and Symptoms (22) · Pathologic Processes (20) · Peritoneal Diseases (18) · Disease Attributes (10) · Female Urogenital Diseases (10) · Female Urogenital Diseases and Pregnancy Complications (10) · Male Urogenital Diseases (10) · Urogenital Diseases (10)
Metronidazole (7) · Appendectomy (5) · Piperacillin, Tazobactam Drug Combination (5) · Amoxicillin-Potassium Clavulanate Combination (3) · Tigecycline (3) · Anti-Bacterial Agents (2) · Bupivacaine (2) · Ceftriaxone (2) · Ciprofloxacin (2) · Clavulanic Acid (2) · Doripenem (2) · Ertapenem (2) · Gentamicins (2) · Morphine (2) · Piperacillin (2)
Medical University of Warsaw (3) · Wyeth is now a wholly owned subsidiary of Pfizer (3) · Chinese University of Hong Kong (2) · Pfizer (2) · Phoenix Children's Hospital (2) · The University of Texas Health Science Center, Houston (2) · A.O. Ospedale Papa Giovanni XXIII (1) · Ahmed Nasr (1) · Alice Ho Miu Ling Nethersole Hospital (1) · Bach Mai Hospital (1) · Baylor College of Medicine (1) · Centre Hospitalier Universitaire de Nīmes (1) · Chiang Mai University (1) · Duke University (1) · Emory University (1)
United States (12) · China (8) · Hong Kong (5) · Italy (5) · Taiwan (4) · Finland (3) · Poland (3) · Australia (2) · Brazil (2) · Canada (2) · France (2) · Indonesia (2) · Malaysia (2) · Thailand (2) · Turkey (Türkiye) (2)
Ahmed Nasr (1) · An-Bang WU, MD (1) · Andrea Biscardi, MD (1) · Antonio Daniele Pinna, MD (1) · Asieh Golozar, MD (1) · Changhong Miao, MD (1) · Chidchanok Ruengorn (1) · Chih-Yang Hsiao, M.D. (1) · Claire Roger, MD (1) · Craig Egan, MD (1) · Cristina Puggioli, MD (1) · Dalya Ferguson, MD, MS (1)
PMID 18178950, PMID 18723709, PMID 19531784, PMID 20670293, PMID 21501482, PMID 22021722, PMID 22134627, PMID 22439781, PMID 23631512, PMID 24578470, PMID 24636429, PMID 24646528, PMID 27283187, PMID 27582784, PMID 29146647, PMID 30584308, PMID 31856900, PMID 33397287, PMID 33846133, PMID 34580704, PMID 35982198, PMID 37717589, PMID 39794723, PMID 41226876, PMID 42157906, PMID 42829121
2016 (1), 2019 (1), K12TR004908 (1)