24 unknown, 20 completed, 11 recruiting, 5 terminated. 10 Phase 4, 9 Not applicable, 9 Phase 2, 8 Phase 3, 4 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Validation of the Italian SCHFI v.8 and the CC-SCHFI v.3 Administration of the Italian version of the SCHFI and the CC-SCHFI, plus other self-reported ouctome measures - Heart Failure | Not yet recruiting | Centro Cardiologico Monzino | 1000 | 2026-05-01 | 2026-05-27 | |
| Antenatal Stress and Infants In MAR Diagnostic procedures - Pregnancy and Medically Assisted Reproduction | Recruiting | IRCCS Eugenio Medea | 100 | 2026-04-01 | 2026-02-13 | |
| Three Different GHDT ( Goal Hemodynamic Directed Therapy) Strategies for Intraoperative Fluid Management Optimization During Major Abdominal Surgery: A Randomized Controlled Trial Flotrac sensor, HPI, HPI-AFM - Hemodynamic | Not applicable | Recruiting | ASST Sette Laghi | 150 | 2026-03-02 | 2026-03-25 |
| Patients With Severe TrIcuspid Regurgitation After triCvALve System Implantation TricValve implantation - Severe Tricuspid Valve Regurgitation | Recruiting | Azienda Ospedaliero, Universitaria Pisana | 100 | 2025-02-01 | 2026-05-11 | |
| Trauma Molecular Processes Traumatic Brain Injury | Recruiting | Mario Negri Institute for Pharmacological Research | 500 | 2024-10-18 | 2026-07-06 | |
| Post-Partum Haemorrhage (PPH) Improvement of Skills With Actor Simulations teamwork job improvement overall, teamwork job improvement in actor scenario vs mannequin scenario - PPH - Postpartum Hemorrhage | Unknown | G. d'Annunzio University | 50 | 2024-05-01 | 2024-04-16 | |
| Precision Medicine in Patients With Unresectable CholAngiocarcinoma: RadioEmbolization and Combined Biological Therapy radioembolization with Y-90, Durvalumab, Cisplatin - Intrahepatic Cholangiocarcinoma | Phase 2 | Recruiting | Francesco De Cobelli | 33 | 2024-04-30 | 2026-09-21 |
| Mesenchymal Stromal Cells for Traumatic Brain Injury Mesenchymal stromal cell low dosage-80*10^6 cells, Mesenchymal stromal cell low dosage-160*10^6 cells, Placebo-storage solution - Traumatic Brain Injury With Loss of Consciousness | Phase 2 | Recruiting | Fondazione IRCCS San Gerardo dei Tintori | 78 | 2023-09-19 | 2023-12-11 |
| ThoRAciC Trauma IntubatiON Risk Score for Blunt Trauma oro tracheal intubation - Trauma Chest | Unknown | Azienda Usl di Bologna | 1000 | 2022-10-01 | 2024-01-31 | |
| Upfront Surgery Versus NeoAdjuvant Chemotherapy Followed by Surgery for Resectable Advanced Gastric Cancer: SNAC Study pre- or perioperative treatment and D2 gastrectomy - Gastric Cancer | Unknown | San Luigi Gonzaga Hospital | 684 | 2022-09-22 | 2024-06-24 | |
| Lung Cancer Prevention Screening Programme in Italy early lung cancer detection, blood test - Lung Cancer, COPD (Chronic Obstructive Pulmonary Disease) With Acute Lower Respiratory Infection | Not applicable | Active not recruiting | Ugo Pastorino | 7324 | 2022-09-17 | 2026-03-27 |
| OPTImal PHARMacological Therapy for Patients With Heart Failure: The OPTIPHARM-HF Registry Heart Failure | Unknown | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | 2000 | 2022-07-18 | 2024-01-05 | |
| Registry for Evaluation of Lumbar Arthrodesis Sagittal alignmEnt Lumbar Spine Disease, Instabilities Lumbar | Unknown | Unit of neurosurgery, Departement of Neurosciences, University of Torino | 500 | 2022-06-01 | 2023-12-04 | |
| This Study Aims to Improve the Stratification of Patients With Acute Myeloid Leukemia to Enable More Personalized and Effective Treatments, and to Identify and Functionally Validate, at the Single-cell Level, Biomarkers That Can Predict Response to Venetoclax. Bulk genotyping of AML samples at diagnosis and relapse, scRNA analysis at diagnosis, scRNAseq and genotyping analysis at day 28 after therapy, spatial transcriptomic analysis at day 0 and 28 - Acute Myeloid Leukemia | Not applicable | Recruiting | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 420 | 2022-05-10 | 2026-10-21 |
| WEANING FROM TRACHEOSTOMY Decannulation - Tracheostomy Weaning, Tracheostomy Decannulation | Completed | University of Milan | 192 | 2022-04-01 | 2025-09-10 | |
| Poor Grade Aneurysmal Subarachnoid Hemorrhage Study Group Standard management according to international/national guidelines - Subarachnoid Hemorrhage, Aneurysmal, Poor Grade Subarachnoid Hemorrhage | Recruiting | IRCCS San Raffaele | 800 | 2021-05-25 | 2023-11-29 | |
| Metabolic Exercise Test Data Combined with Cardiac and Kidney Indexes (MECKI) Score Evolution: Identification of Cardiovascular Risk in Patients with Heart Failure Heart Failure | Recruiting | Centro Cardiologico Monzino | 10000 | 2021-02-10 | 2025-03-19 | |
| Effects of Mindfulness Therapy in Patients With Acromegaly and Cushing Mindfulness, Control - Patient Satisfaction | Not applicable | Completed | Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau | 60 | 2020-09-01 | 2023-03-16 |
| FAst and SimplE COVID-19 Causing Virus SARS-CoV-2 Detection Swab sampling - COVID-19 | Completed | University of Milano Bicocca | 200 | 2020-08-01 | 2022-04-22 | |
| Web-based International Register of Emergency Surgery and Trauma Emergency General Surgery - Acute Appendicitis, Acute Cholecystitis | Recruiting | A.O. Ospedale Papa Giovanni XXIII | 10000 | 2020-07-01 | 2020-07-14 |
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COVID-19 (5) · Coronary Artery Disease (4) · HIV Infections (4) · Thrombosis (4) · Heart Failure (3) · Hematologic Neoplasms (3) · Appendicitis (2) · Brain Injuries, Traumatic (2) · Lymphoma, Non-Hodgkin (2) · Wounds and Injuries (2) · Acquired Immunodeficiency Syndrome (1) · Acute Coronary Syndrome (1) · Arrhythmias, Cardiac (1) · Cardiovascular Diseases (1) · Cholangiocarcinoma (1)
Percutaneous Coronary Intervention (2) · Appendectomy (1) · Cell Count (1) · Cetuximab (1) · Cisplatin (1) · Cobicistat (1) · Cyclophosphamide (1) · Cytoreduction Surgical Procedures (1) · Darunavir (1) · Deep Brain Stimulation (1) · Doxorubicin (1) · Ertapenem (1) · Everolimus (1) · Gemcitabine (1) · Hematologic Tests (1)
Italy (57) · Germany (3) · Spain (2) · Austria (1) · Belgium (1) · Canada (1) · Czechia (1) · Ireland (1) · Latvia (1) · Netherlands (1) · Norway (1) · United Kingdom (1) · United States (1)
Giulio Guagliumi, MD (7) · Alessandro Rambaldi, MD (5) · Franco Maggiolo, MD (3) · Alessandro AR Rambaldi, Professor (1) · Alfonso W Avolio, MD (1) · Anna Falanga, MD (1) · Anthony H Gershlick (1) · Armando Santoro, MD (1) · Bruno Ferraro, MD (1) · Claudio Celentano, MD (1) · Cortelazzo Sergio, MD (1) · Dario Tartaglia, MD (1) · Eugenia Resmini, MD, PhD (1) · Federica Casiraghi (1)
PMID 11255275, PMID 11441933, PMID 12011122, PMID 12149300, PMID 12652460, PMID 15090796, PMID 15097290, PMID 16107348, PMID 16732175, PMID 16980990, PMID 17151341, PMID 17606446, PMID 18468541, PMID 18703664, PMID 18820709, PMID 19462317, PMID 20350611, PMID 20488410, PMID 20630463, PMID 20685246, PMID 21393326, PMID 21417678, PMID 21777886, PMID 22298797, PMID 22431208, PMID 23216616, PMID 24467608, PMID 26279673, PMID 28239409, PMID 29963053, PMID 31602518, PMID 32014041, PMID 32129855, PMID 32833107, PMID 34276706, PMID 35485333, PMID 36326921, PMID 37010298, PMID 37160552, PMID 41884465, PMID 8636765
2008 (1)