9 completed, 1 terminated. 10 Phase 1, 4 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 10 | Completed 9, Terminated 1 |
| Phase 2 | 4 | Completed 3, Terminated 1 |
Follow Intestinal Obstruction: new trials by email Literature Review of Intestinal Obstruction trials Research Report on Intestinal Obstruction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Follow-up and Steroid Treatment Results in Intussusception Methylprednisolone - Intussusception | Phase 1 / Phase 2 | Completed | Baskent University | 92 | 2019-12-24 | 2025-02-05 |
| A Study to Evaluate the Safety, Tolerability and Efficacy of LB1148 for Subjects Undergoing Elective Bowel Resection Tranexamic Acid - Adhesions, Ileus | Phase 1 | Completed | Ronald Hurst, MD, FACS | 11 | 2018-11-05 | 2020-12-04 |
| Therapeutic Oxygen for Gastrointestinal Atony (TOGA) 100% Oxygen - Ileus, Ogilvie Syndrome | Phase 1 | Completed | University of Florida | 17 | 2018-01-25 | 2019-12-12 |
| Effects of Methylnaltrexone in Comparison to Naloxone on Loperamide-induced Delay of the Oro-cecal, Whole-gut and Colon Transit Time. Loperamide placebo, Loperamide, Colon Transit - Intestinal Obstruction | Phase 1 | Completed | University Medicine Greifswald | 16 | 2011-05-01 | 2012-05-11 |
| Interventions to Decrease the Impact of Post-OPerative Ileus After Liver Transplant or Resection Surgery stool softener, Arm B: Acupressure bracelet, sugar free gum - Ileus | Phase 1 | Completed | University of Nebraska | 111 | 2010-09-01 | 2023-09-07 |
| Trial of Best Supportive Care and Either Cisplatin or Paclitaxel to Treat Patients With Primary Ovarian Cancer, Primary Peritoneal Cancer or Fallopian Tube Cancer and Inoperable Malignant Bowel Obstruction Cisplatin, Paclitaxel - Ovarian Cancer, Peritoneal Cancer | Phase 1 / Phase 2 | Terminated | University Health Network, Toronto | 1 | 2010-02-01 | 2019-02-15 |
| Effects of 500 mg Immediate Release and Extended Release Methylnaltrexone on Loperamide-induced Delay of the Oro-cecal and Whole-gut Transit Time in Healthy Subjects Loperamide, Loperamide placebo, Methylnaltrexone placebo - Intestinal Obstruction | Phase 1 | Completed | University Medicine Greifswald | 15 | 2010-01-01 | 2016-10-26 |
| Study Evaluating the Safety of MOA-728 Administered Orally to Healthy Subjects MOA-728 - Postoperative Complications, Constipation | Phase 1 | Completed | Bausch Health Americas, Inc. | 48 | 2006-03-01 | 2019-11-25 |
| Endoscopic Placement of Metal Stents in Treating Patients With Cancer- Related Duodenal Obstruction bowel obstruction management, quality-of-life assessment - Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction | Phase 1 / Phase 2 | Completed | Northwestern University | 2000-01-01 | 2012-06-06 | |
| Endoscopic Placement of Metal Stent in Patients With Cancer-Related Bowel Obstruction bowel obstruction management, quality-of-life assessment - Colorectal Cancer, Constipation, Impaction, and Bowel Obstruction | Phase 1 / Phase 2 | Completed | Northwestern University | 2000-01-01 | 2012-06-06 |
Ileus (4) · Constipation (3) · Colonic Neoplasms (2) · Colorectal Neoplasms (2) · Gastrointestinal Stromal Tumors (2) · Stomach Neoplasms (2) · Bile Duct Neoplasms (1) · Colonic Pseudo-Obstruction (1) · Fallopian Tube Neoplasms (1) · Intestinal Perforation (1) · Intussusception (1) · Ovarian Neoplasms (1) · Pancreatic Neoplasms (1) · Postoperative Complications (1)
Digestive System Diseases (10) · Gastrointestinal Diseases (10) · Intestinal Diseases (10) · Pathological Conditions, Signs and Symptoms (4) · Colonic Diseases (3) · Neoplasms (3) · Neoplasms by Site (3) · Signs and Symptoms (3) · Signs and Symptoms, Digestive (3) · Digestive System Neoplasms (2) · Endocrine Gland Neoplasms (2) · Endocrine System Diseases (2) · Gastrointestinal Neoplasms (2) · Intestinal Neoplasms (2)
Loperamide (2) · Sulfasalazine (2) · methylnaltrexone (2) · Bisacodyl (1) · Cisplatin (1) · Dioctyl Sulfosuccinic Acid (1) · Drugs, Generic (1) · Magnesium Hydroxide (1) · Methylprednisolone (1) · Naloxone (1) · Oxygen (1) · Paclitaxel (1) · Steroids (1) · Tranexamic Acid (1)
Northwestern University (2) · University Medicine Greifswald (2) · Baskent University (1) · Bausch Health Americas, Inc. (1) · Ronald Hurst, MD, FACS (1) · University Health Network, Toronto (1) · University of Florida (1) · University of Nebraska (1)
United States (6) · Germany (2) · Canada (1) · Turkey (Türkiye) (1)
Willis G. Parsons, MD, PC (2) · Amit Oza (1) · Brian C. Weiner, MD (1) · Jeff Cohn (1) · Laurel W Williams, MSN,RN (1) · Nicole Chau (1) · Ronald Hurst, MD (1)