16 completed, 7 terminated, 4 unknown, 1 withdrawn. 28 Phase 2, 4 Phase 1, 2 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 28 | Completed 16, Terminated 7, Unknown 4, Withdrawn 1 |
| Phase 1 | 4 | Completed 3, Terminated 1 |
| Phase 3 | 2 | Completed 1, Withdrawn 1 |
Follow Intestinal Obstruction: new trials by email Literature Review of Intestinal Obstruction trials Research Report on Intestinal Obstruction
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Comparing Intrathecal Morphine and Intraoperative Lidocaine Infusion to Epidural Anesthesia With Postoperative PCA for Patients Undergoing Exploratory Laparotomy Bupivacaine, Morphine, Lidocaine - Cancer Debulking, Enlarged Uterus | Phase 2 | Terminated | Washington University School of Medicine | 110 | 2022-01-18 | 2025-07-31 |
| Efficacy and Safety of Rifaximin for Patients With Chronic Intestinal Pseudo-obstruction: a Phase 2 Trial Rifaximin oral tablet, Placebo oral tablet - Chronic Intestinal Pseudo-obstruction | Phase 2 | Unknown | Yokohama City University | 12 | 2019-12-25 | 2021-06-21 |
| Follow-up and Steroid Treatment Results in Intussusception Methylprednisolone - Intussusception | Phase 1 / Phase 2 | Completed | Baskent University | 92 | 2019-12-24 | 2025-02-05 |
| A Study to Evaluate LB1148 for Return of Gastrointestinal Function and Adhesions in Subjects Undergoing Bowel Resection LB1148, Placebo - Ileus, Post-Operative Adhesions | Phase 2 | Completed | Palisade Bio | 112 | 2019-10-01 | 2024-06-21 |
| Study to Evaluate LB1148 for Return of Gastrointestinal Function, Decrease Post-Operative Ileus LB1148, Placebo - Ileus | Phase 2 | Completed | Newsoara Biopharma Co., Ltd. | 131 | 2019-07-09 | 2021-09-27 |
| Palliative Management of Inoperable Malignant Bowel Obstruction Dexamethasone, Metoclopramide, Octreotide - Malignant Bowel Obstruction | Phase 2 | Terminated | Roswell Park Cancer Institute | 15 | 2019-06-26 | 2022-11-29 |
| Subcutaneous Methylnaltrexone Versus Placebo for Postoperative Ileus Prevention Methylnaltrexone, Placebo - Postoperative Ileus | Phase 2 | Completed | Ohio State University | 82 | 2019-02-21 | 2021-10-27 |
| The Effect of Foeniculum Vulgare Ironing on Gastrointestinal Recovery After Colorectal Resection Foeniculum Vulgare Seed Ironing - Colorectal Surgery, Foeniculum | Phase 2 | Completed | West China Hospital | 300 | 2018-10-20 | 2019-09-17 |
| Does Cediranib Prevent Bowel Perforation in Platinum-resistant Ovarian Cancer Cediranib - Bowel Obstruction, Ovarian Cancer | Phase 2 | Completed | Prof Gordon Jayson | 30 | 2018-05-14 | 2026-06-15 |
| Phase 2 RCT of Alvimopan vs. Placebo After CRS/HIPEC Alvimopan, Placebo - Ileus | Phase 2 | Terminated | University of California, San Diego | 84 | 2018-03-08 | 2021-08-18 |
| Use of Gastrografin in the Management of Fecal Impaction in Patients With Severe Chronic Constipation Gastrografin, enemas - Fecal Impaction | Phase 2 | Unknown | Jinling Hospital, China | 83 | 2015-04-01 | 2017-08-09 |
| Quality of Life in Patients With Inoperable Malignant Bowel Obstruction lanreotide (Autogel formulation) - Intestinal Obstruction | Phase 2 | Terminated | Ipsen | 43 | 2015-01-01 | 2019-11-22 |
| Stimulation of the Efferent Loop Before Loop Ileostomy Closure efferent limb stimulation - Ileostomy - Stoma, Ileostomy; Complications | Phase 2 | Unknown | Hospital de Basurto | 140 | 2014-11-20 | 2018-02-07 |
| Study to Assess Efficacy and Safety of Lanreotide Autogel 120 MG in Treatment of Clinical Symptoms Associated With Inoperable Malignant Intestinal Obstruction Lanreotide Autogel - Intestinal Obstruction | Phase 2 | Completed | Ipsen | 52 | 2014-11-19 | 2019-04-16 |
| Daikenchuto for Intestinal Dysmotility and Prevention of Postoperative Paralytic Ielus After Pancreaticoduodenectomy Oral/enteral TJ-100 solution, Oral/enteral placebo solution - Paralytic Ileus | Phase 2 | Unknown | Wakayama Medical University | 220 | 2012-08-01 | 2013-12-18 |
| Effects of Gum Chewing on Recovery of Bowel Function Following Abdominal Surgery for Endometrial and Ovarian Cancer Gum chewing - Paralytic Ileus | Phase 2 / Phase 3 | Withdrawn | Chiang Mai University | 2011-07-01 | 2016-08-30 | |
| Study of Inhaling Carbon Monoxide to Treat Patients With Intestinal Paralysis After Colon Surgery. Inhaled Carbon Monoxide, Synthetic Air - Ileus | Phase 2 | Terminated | Queen's University | 3 | 2011-04-01 | 2015-11-17 |
| The Effects of Gum Chewing on Bowel Function Recovery Following Cesarean Section Gum chewing - Paralytic Ileus | Phase 2 / Phase 3 | Completed | Chiang Mai University | 100 | 2010-05-01 | 2011-06-28 |
| Efficacy, Safety, and Tolerability of JNJ-27018966 (Eluxadoline) in the Treatment of Irritable Bowel Syndrome With Diarrhea Eluxadoline, Placebo - Irritable Bowel Syndrome | Phase 2 | Completed | Furiex Pharmaceuticals, Inc | 807 | 2010-04-28 | 2019-10-22 |
| Trial of Best Supportive Care and Either Cisplatin or Paclitaxel to Treat Patients With Primary Ovarian Cancer, Primary Peritoneal Cancer or Fallopian Tube Cancer and Inoperable Malignant Bowel Obstruction Cisplatin, Paclitaxel - Ovarian Cancer, Peritoneal Cancer | Phase 1 / Phase 2 | Terminated | University Health Network, Toronto | 1 | 2010-02-01 | 2019-02-15 |
Showing 20 of 28. Sign in to see all of them.
Ileus (11) · Intestinal Pseudo-Obstruction (4) · Colonic Neoplasms (3) · Colorectal Neoplasms (3) · Constipation (3) · Gastrointestinal Stromal Tumors (3) · Ovarian Neoplasms (3) · Stomach Neoplasms (3) · Bile Duct Neoplasms (2) · Fallopian Tube Neoplasms (2) · Fecal Impaction (2) · Pancreatic Neoplasms (2) · Peritoneal Neoplasms (2) · Rectal Neoplasms (2)
Digestive System Diseases (27) · Gastrointestinal Diseases (27) · Intestinal Diseases (27) · Neoplasms (8) · Neoplasms by Site (7) · Digestive System Neoplasms (5) · Ileus (5) · Neoplasms by Histologic Type (5) · Pathological Conditions, Signs and Symptoms (5) · Signs and Symptoms (5) · Endocrine Gland Neoplasms (4) · Endocrine System Diseases (4) · Neoplasms, Connective and Soft Tissue (4) · Adnexal Diseases (3)
Octreotide (3) · Chewing Gum (2) · Methylprednisolone (2) · Acupuncture Therapy (1) · Bupivacaine (1) · Cilastatin, Imipenem Drug Combination (1) · Cisplatin (1) · Dexamethasone (1) · Doripenem (1) · Enema (1) · Exercise (1) · Lactulose (1) · Lidocaine (1) · Metoclopramide (1) · Morphine (1)
Northwestern University (3) · Chiang Mai University (2) · Ipsen (2) · Baskent University (1) · Furiex Pharmaceuticals, Inc (1) · Helsinn Therapeutics (U.S.), Inc (1) · Hospital de Basurto (1) · Jinling Hospital, China (1) · Johnson & Johnson Pharmaceutical Research & Development, L.L.C. (1) · National Center for Complementary and Integrative Health (NCCIH) (1) · Newsoara Biopharma Co., Ltd. (1) · Norgine (1) · Novartis Pharmaceuticals (1) · Ohio State University (1) · Palisade Bio (1)
United States (11) · China (3) · Canada (2) · Japan (2) · Thailand (2) · United Kingdom (2) · Belgium (1) · France (1) · Italy (1) · Spain (1) · Turkey (Türkiye) (1)
Kittipat Charoenkwan, MD (2) · Willis G. Parsons, MD, PC (2) · Amit Oza (1) · Amy Case, MD (1) · Andrew Clamp (1) · David CA Candy, MD (1) · Hiroki Yamaue, M.D., Ph.D. (1) · J. Cameron Muir, MD (1) · Joel M Baumgartner, MD, MAS (1) · Joseph S Chiang, MD (1) · Mitch Jones, MD (1)
PMID 15351109, PMID 16819379, PMID 16850151, PMID 19610681, PMID 20334152, PMID 23583433, PMID 24813429, PMID 25331030, PMID 25819420, PMID 26747224, PMID 26867333, PMID 28167156, PMID 29067571, PMID 29621360, PMID 30333892, PMID 34798295, PMID 34844770, PMID 36102565, PMID 39914152
2016 (1)