10 completed, 1 active not recruiting, 1 recruiting, 1 terminated. 5 Phase 1, 4 Not applicable, 3 Phase 2, 2 Phase 3, 2 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 5 | Completed 5 |
| Not applicable | 4 | Completed 3, Active not recruiting 1 |
| Phase 2 | 3 | Completed 2, Unknown 1 |
| Phase 3 | 2 | Terminated 1, Unknown 1 |
| Phase 4 | 2 | Completed 1, Recruiting 1 |
Follow Magnesium Hydroxide: new trials by email Literature Review of Magnesium Hydroxide trials Research Report on Magnesium Hydroxide
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 12-week Magnesium Supplementation on Peri-menopause Symptoms, Cognition, Sleep, and Psychological Well-being Placebo, Magnesium hydroxide 375mg - Perimenopause, Perimenopausal Women | Not applicable | Active not recruiting | Northumbria University | 58 | 2025-12-09 | 2026-08-05 |
| Prevention of Opioid-induced Constipation in Patients With Advanced Cancer Macrogol Only Product in Oral Dose Form, Magnesium hydroxide 724mg - Constipation, Opioid-Induced | Phase 4 | Recruiting | Amsterdam UMC, location VUmc | 258 | 2022-12-02 | 2026-10-05 |
| RELISTOR's Effects on Opioid-Induced Constipation Relistor Injectable Product, Docusate Calcium, Bisacodyl - OIC | Withdrawn | Methodist Health System | 2021-07-01 | 2026-03-23 | ||
| The Impact of Air Travel on Passenger Cognitive Functions Citicoline, Cytochrome C6, Sodium Chloride Oral Product - Air Travel | Phase 2 / Phase 3 | Unknown | Dinara Zhumanbayeva | 50 | 2021-06-01 | 2021-03-17 |
| Study to Examine the Effect of Antacid and Omeprazole on the Single-Dose Pharmacokinetics of Tebipenem Pivoxil Hydrobromide (TBPM-PI-HBr) in Healthy Adult Subjects Tebipenem pivoxil hydrobromide (TBPM-PI-HBr), 20 mL aluminum hydroxide/magnesium hydroxide/simethicone (400 mg aluminum hydroxide/400 mg magnesium hydroxide/40 mg simethicone per 5 mL), Omeprazole - Healthy Volunteers | Phase 1 | Completed | Spero Therapeutics | 20 | 2020-07-01 | 2020-09-04 |
| Study to Assess the Way the Body Absorbs, Distributes, Breaks Down and Eliminates Radioactive BMS-986256 in Healthy Male Participants BMS-986256, Milk of magnesia - Healthy Participants | Phase 1 | Completed | Bristol-Myers Squibb | 8 | 2020-02-18 | 2022-01-10 |
| Magnesium Supplementation for Hypomagnesemia in Chronic Kidney Disease Mablet 360 mg, Placebo - Chronic Kidney Disease, Hypomagnesemia | Phase 1 / Phase 2 | Completed | Zealand University Hospital | 36 | 2014-08-01 | 2015-04-28 |
| Methylnaltrexone Use for Opioid-induced Postoperative Constipation Methylnaltrexone, Senna, docusate sodium, bisacodyl, magnesium hydroxide, Miralax - Constipation | Phase 4 | Completed | Shriners Hospitals for Children | 60 | 2013-05-01 | 2015-05-19 |
| MiraLAX Versus Placebo to Prevent Constipation Following Urogynecologic Surgery MiraLax, Placebo, Rescue Laxative - Post Procedural Constipation | Not applicable | Completed | Duke University | 131 | 2012-09-01 | 2017-02-15 |
| Tepilta® Versus Oxetacaine, Antacids and Placebo oxetacaine, aluminium and magnesium hydroxide, oxetacaine, magnesium and aluminium hydroxide - Radiation-induced Oesophagitis | Phase 3 | Terminated | MEDA Pharma GmbH & Co. KG | 40 | 2011-04-01 | 2022-02-07 |
| Bronchial Challenge Test of Magnesium-treated Asthmatics Magnesium supplement (magnesium hydroxide/ -oxide), Placebo - Asthma | Not applicable | Completed | University of Aarhus | 12 | 2010-10-01 | 2013-09-04 |
| Daily Magnesium-treatment of Patients With Chronic Obstructive Pulmonary Disease Magnesium supplement (magnesium hydroxide/ -oxide), Placebo - COPD | Not applicable | Completed | University of Aarhus | 11 | 2010-10-01 | 2013-09-04 |
| Interventions to Decrease the Impact of Post-OPerative Ileus After Liver Transplant or Resection Surgery stool softener, Arm B: Acupressure bracelet, sugar free gum - Ileus | Phase 1 | Completed | University of Nebraska | 111 | 2010-09-01 | 2023-09-07 |
| Proof of Concept Study Efficacy of an Antacid/Lansoprazole Combination for Relief of Heartburn Calcium carbonate/magnesium hydroxide/Lansoprazole 15 mg, Lansoprazole, Calcium carbonate/magnesium hydroxide - Heartburn | Phase 2 | Completed | Novartis | 120 | 2009-12-01 | 2011-03-28 |
| A Study to Assess the Bioequivalence of Famotidine/Antacid Combination Tablets Compared to Famotidine/Antacid EZ Chew Tablets (0208C-145)(COMPLETED) famotidine (+) calcium carbonate (+) magnesium hydroxide tablet, Comparator: famotidine (+) calcium carbonate (+) magnesium hydroxide EZ Chew tablet without water, Comparator: famotidine (+) calcium carbonate (+) magnesium hydroxide EZ Chew tablet with water - Heartburn | Phase 1 | Completed | Johnson & Johnson Consumer and Personal Products Worldwide | 24 | 2008-02-01 | 2015-06-24 |
Heartburn (2) · Asthma (1) · Cancer Pain (1) · Constipation (1) · Ileus (1) · Neoplasms (1) · Opioid-Induced Constipation (1) · Pulmonary Disease, Chronic Obstructive (1) · Renal Insufficiency, Chronic (1)
University of Aarhus (2) · Amsterdam UMC, location VUmc (1) · Bristol-Myers Squibb (1) · Dinara Zhumanbayeva (1) · Duke University (1) · Johnson & Johnson Consumer and Personal Products Worldwide (1) · MEDA Pharma GmbH & Co. KG (1) · Methodist Health System (1) · Northumbria University (1) · Novartis (1) · Shriners Hospitals for Children (1) · Spero Therapeutics (1) · University of Nebraska (1) · Zealand University Hospital (1)
United States (7) · Denmark (3) · Austria (1) · Germany (1) · Netherlands (1) · United Kingdom (1)
Ronald Dahl, Professor (2) · Anthony G Visco, MD (1) · David Melnick, M.D. (1) · Deborah J. Vermaire, M.D. (1) · Frank Bruns, Dr. med. (1) · Iain B Bressendorff, MD (1) · Laurel W Williams, MSN,RN (1) · Lia van Zuylen, Prof.dr. (1) · Richard Meyrat, MD (1) · Ursula Petzold, PhD (1)
PMID 21998076, PMID 27500338, PMID 36915062
2009 (1)