38 completed, 14 unknown, 9 recruiting, 6 terminated. 20 Phase 4, 16 Phase 3, 14 Phase 2, 13 Phase 1, 4 Not applicable.
Follow Sulfasalazine: new trials by email Literature Review of Sulfasalazine trials Research Report on Sulfasalazine
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| The Effect of Nicorandil on Rheumatoid Arthritis Patients Nicorandil Oral Tablet, Placebo, conventional synthetic antirheumatic drugs (cDMARDs) - Rheumatoid Arthritis (RA) | Phase 2 / Phase 3 | Recruiting | Ain Shams University | 70 | 2026-09-06 | 2026-09-16 |
| Study of ECC4703 With Sulfasalazine and Pitavastatin ECC4703, Sulfasalazine, Pitavastatin - Non-alcoholic Fatty Liver Disease (NAFLD), Dyslipidaemia | Phase 1 | Recruiting | Eccogene | 40 | 2026-08-07 | 2026-09-10 |
| Immunosuppressant Management in Rheumatology Patients Undergoing Elective Total Shoulder Arthroplasty Methotrexate, Sulfasalazine, Hydroxychloroquine - Rheumatic Disease | Phase 2 | Recruiting | NYU Langone Health | 80 | 2025-12-12 | 2026-07-09 |
| MRD Guided De-intensification of Bendamustine/Rituximab for Indolent Non-Hodgkin Lymphoma Bendamustine, Rituximab - Lymphoma, Indolent Non-hodgkin Lymphoma | Phase 2 | Not yet recruiting | Fox Chase Cancer Center | 24 | 2025-06-01 | 2025-01-06 |
| A Prospective, Single Arm, Open Label, Proof of Concept Clinical Study of Sulfasalazine in the Treatment of Active Systemic Lupus Erythematosus Sulfasalazine Tablets - Systemic Lupus Erythematosus | Phase 2 | Unknown | Qiong Fu | 20 | 2024-05-06 | 2024-04-11 |
| Sulfasalazine in Patients With Metastatic Colorectal Cancer Sulfasalazine - Metastatic Colorectal Cancer | Phase 3 | Unknown | Tanta University | 50 | 2023-09-01 | 2023-11-18 |
| Sulfasalazine in AML Treated by Intensive Chemotherapy: Elderly Patients-first Line Treatment Sulfasalazine - Acute Myeloid Leukemia | Phase 1 / Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 64 | 2023-05-17 | 2024-05-29 |
| Topical Sulfasalazine and Oral Lichen Planus sulfasalazine 500 MG, corticosteroids - Oral Lichen Planus, Topical Sulfasalazine | Phase 3 | Unknown | Cairo University | 46 | 2023-03-01 | 2024-08-01 |
| The Effect of Sulfasalazine on CRH Levels in Pregnant Women Sulfasalazine - Preterm Birth | Phase 2 | Recruiting | Rutgers, The State University of New Jersey | 50 | 2023-03-01 | 2026-07-09 |
| Glutamate Inhibitors in Glioblastoma Gabapentin, Sulfasalazine, Memantine - Glioblastoma | Phase 1 / Phase 2 | Recruiting | University of Zurich | 120 | 2023-01-01 | 2024-05-10 |
| A Study to Assess the Effects of BMS-986371 on the Drug Levels of Methotrexate in the Presence and Absence of Sulfasalazine Methotrexate, Leucovorin, BMS-986371 - Healthy Participants | Phase 1 | Completed | Bristol-Myers Squibb | 30 | 2022-09-06 | 2023-02-08 |
| Sulfasalazine in Decreasing Opioids Requirements in Breast Cancer Patients Sulfasalazine, Placebos - Breast Cancer, Chronic Pain Due to Malignancy (Finding) | Phase 2 | Completed | University of Arizona | 7 | 2021-05-03 | 2025-01-09 |
| Drug-drug Interaction Study with GLPG3970 and Sulfasalazine in Adult, Healthy Subjects Sulfasalazine, GLPG3970 - Healthy | Phase 1 | Completed | Lakefront Biotherapeutics NV | 8 | 2021-01-11 | 2024-09-19 |
| Impact of Tapering Immunosuppressants on Maintaining Minimal Disease Activity in Adult Subjects With Psoriatic Arthritis Prednisolone, Sulfasalazine, Leflunomide - Psoriatic Arthritis, Withdrawal | Phase 3 | Unknown | University of Erlangen-Nürnberg Medical School | 270 | 2020-10-19 | 2022-11-14 |
| Pilot Study of the Safety and Efficacy of Sulfasalazine in Pulmonary Arterial Hypertension Sulfasalazine, Ambrisentan, Sulfasalazine's placebo - Pulmonary Arterial Hypertension | Phase 1 / Phase 2 | Unknown | RenJi Hospital | 80 | 2020-08-01 | 2020-08-27 |
| A Study to Evaluate Potential Cytochrome P450 and Transporter Protein Interactions With CC-99677 CC-99677, Methotrexate, Sulfasalazine - Healthy Volunteer | Phase 1 | Completed | Celgene | 48 | 2020-03-13 | 2021-08-18 |
| Sulfasalazine and Stereotactic Radiosurgery for Recurrent Glioblastoma Sulfasalazine - Glioma, Glioblastoma | Phase 1 | Completed | Haukeland University Hospital | 24 | 2020-03-01 | 2023-03-03 |
| Treat-to-target Strategy in Ankylosing Spondylitis Using Etanercept and Conventional Synthetic DMARDs Methotrexate, Sulfasalazine, Hydroxychloroquine - Ankylosing Spondylitis, Spondyloarthritis | Phase 4 | Unknown | Nanfang Hospital, Southern Medical University | 100 | 2019-10-07 | 2019-09-26 |
| Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial Methotrexate, Sulfasalazine, Leflunomide - Psoriatic Arthritis | Phase 4 | Completed | University of Oxford | 192 | 2019-05-14 | 2025-11-26 |
| Psoriatic Oligoarthritis Intervention With Symptomatic thErapy Methotrexate, Sulfasalazine, Leflunomide - Psoriatic Arthritis | Phase 4 | Completed | University of Oxford | 1 | 2019-04-17 | 2021-05-10 |
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Arthritis, Rheumatoid (26) · Spondylitis, Ankylosing (8) · Arthritis, Psoriatic (4) · Arthritis, Juvenile (2) · Glioblastoma (2) · Intestinal Obstruction (2) · Lupus Erythematosus, Systemic (2) · Rheumatic Diseases (2) · Spondylarthritis (2) · Alcoholism (1) · Arthralgia (1) · Autoimmune Diseases (1) · Axial Spondyloarthritis (1) · Brain Neoplasms (1) · Breast Neoplasms (1)
Sanofi (5) · University Medicine Greifswald (3) · Brigham and Women's Hospital (2) · Karolinska Institutet (2) · Nanfang Hospital, Southern Medical University (2) · University of Alabama at Birmingham (2) · University of Leeds (2) · University of Nebraska (2) · University of Oxford (2) · Wyeth is now a wholly owned subsidiary of Pfizer (2) · Ain Shams University (1) · Akebia Therapeutics (1) · Alliance for Clinical Trials in Oncology (1) · Assistance Publique - Hôpitaux de Paris (1) · Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh (1)
United States (24) · United Kingdom (7) · Germany (6) · Sweden (5) · Australia (4) · China (4) · France (4) · Mexico (4) · Poland (4) · Canada (3) · Czechia (3) · Egypt (3) · Finland (3) · Hungary (3) · Italy (3)
James R O'Dell, MD (2) · Bente S Skeie (1) · Brian J Wainger, MD, PhD (1) · Carel W le Roux, FRCP FRCPath PhD (1) · Daniel Solomon (1) · David Seligson, MD (1) · Dennis Vargo, MD (1) · Emily Rosenfeld, DO (1) · Faculty O Dentistry, Cairo University (1)
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