589 completed, 147 recruiting, 135 unknown, 74 not yet recruiting. 720 Not applicable, 76 Phase 4, 69 Phase 2, 60 Phase 3, 44 Phase 1.
Follow Insomnia: new trials by email Literature Review of Insomnia trials Research Report on Insomnia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Buddhist Awareness Training Program and Qigong Psychosocial Interventions for People With Insomnia Psychosocial intervention - Insomnia, Randomised Controlled Trial | Not applicable | Suspended | College of Professional and Continuing Education Limited | 86 | 2030-01-01 | 2026-03-19 |
| Telenursing-Based Sleep Coaching for Adults Living With HIV With Insomnia Symptoms Telenursing-based sleep coaching - Insomnia, HIV Infections | Not applicable | Not yet recruiting | Universitas Indonesia | 50 | 2027-04-01 | 2026-10-23 |
| Study of Bedroom Environment Sleep Intervention at Home for Older Adults Living Alone With Memory Concerns Bedroom Environment Tailoring, Sleep Health Education - Subjective Cognitive Decline (SCD), Mild Cognitive Impairment (MCI) | Not applicable | Not yet recruiting | Johns Hopkins University | 40 | 2027-02-01 | 2026-10-09 |
| Racism-related Stress and Objective Short-sleep as Moderators of Treatment Effect in Cognitive Behavioral Therapy for Insomnia Cognitive Behavioral Therapy for Insomnia (CBTi) - Insomnia, Stress | Not applicable | Not yet recruiting | Johns Hopkins University | 100 | 2027-01-01 | 2026-09-10 |
| Web-Based Insomnia Treatment for Spousal Dementia Caregivers (SHUTi-DC) SHUTi-DC, PE - Insomnia | Not applicable | Not yet recruiting | University of Missouri-Columbia | 80 | 2027-01-01 | 2026-09-23 |
| Transcendental Meditation Intervention to Reduce Burnout and Enhance Resilience Among NewYork-Presbyterian Hospital and Weill Cornell Medicine Employees and Residents Transcendental Meditation - Anxiety, Depression - Major Depressive Disorder | Not applicable | Not yet recruiting | Weill Medical College of Cornell University | 15 | 2026-11-15 | 2026-10-09 |
| Does the Timing of Insomnia Therapy (CBT-i) Impact the Usage and Compliance of Upper Airway Stimulation (UAS) Treatment of Obstructive Sleep Apnea (OSA) Digital Cognitive Behavioral Therapy (CBT-i)-COAST - Obstructive Sleep Apnea, Comorbid Insomnia and Sleep Apnea | Not applicable | Not yet recruiting | Thomas Kaffenberger | 100 | 2026-11-05 | 2026-09-24 |
| SleepSMART for Veterans With Insomnia and Mild Cognitive Impairment Cognitive BehavioralTherapy for Insomnia (CBT-I), SleepSMART - Insomnia, Mild Cognitive Impairment | Not applicable | Not yet recruiting | VA Office of Research and Development | 150 | 2026-11-02 | 2026-07-23 |
| Enhancing Operational Readiness With Digital Self-Managed Cognitive Behavioral Therapy for Insomnia (CBTI) Cognitive Behavioral Therapy for Insomnia - Insomnia, Depression - Major Depressive Disorder | Not applicable | Not yet recruiting | Madigan Army Medical Center | 144 | 2026-11-01 | 2026-10-22 |
| AI-Driven Digital Therapeutic for Insomnia: Development and Clinical Validation Digital BBTI-Based Sleep Management, AI-Assisted Sleep Education and Personalized Guidance - Insomnia | Not applicable | Not yet recruiting | Taipei Medical University | 60 | 2026-11-01 | 2026-10-28 |
| Efficacy of Digital CBT-I Utilizing Embodied Artificial Intelligence Agent in Virtual Reality App-based dCBT-I with AI chatbot, VR-enhanced dCBT-I with embodied AI agent - Insomnia | Not applicable | Not yet recruiting | Chinese University of Hong Kong | 168 | 2026-10-23 | 2026-07-16 |
| Effectiveness of a Guided, Web-based, Stepped-care-approach to Cognitive Behavioral Therapy for Insomnia in Cancer Survivors Stepped-care Cognitive Behavioral Therapy for Insomnia, Standard web-based Cognitive Behavioral Therapy for Insomnia, Control arm - Care as usual with sleep hygiene leaflet - Neoplasms, Cancer Survivorship | Not applicable | Not yet recruiting | Vrije Universiteit Brussel | 140 | 2026-10-15 | 2026-10-15 |
| A Theory-based Sleep Hygiene Education for Insomnia Disorder Sleep Hygiene Education, CBT-I Apps - Insomnia, Adults | Not applicable | Not yet recruiting | The Hong Kong Polytechnic University | 264 | 2026-10-10 | 2026-09-24 |
| A Multicenter Observational Study of Daridorexant in the Treatment of Insomnia Daridorexant 50 mg - Insomnia | Not yet recruiting | Shanghai Mental Health Center | 500 | 2026-10-01 | 2026-09-29 | |
| Qing-Xin-Jiao-Tai Decoction for Insomnia Comorbid With Obesity Presenting With Heart-Kidney Non-interaction Syndrome Qingxin Jiaotai Decoction, Placebo - Insomnia, Obesity | Early Phase 1 | Not yet recruiting | Fohow Pharmaceutical Group | 72 | 2026-10-01 | 2026-08-10 |
| THC Versus THC/CBD Versus Placebo to Improve Sleep Quality for Patients With Solid Organ Cancer and Insomnia Biospecimen Collection, Placebo Administration, Single Agent Therapy - Insomnia, Malignant Solid Neoplasm | Phase 2 | Not yet recruiting | Mayo Clinic | 69 | 2026-10-01 | 2026-09-02 |
| Transcutaneous Auricular Vagus Nerve Stimulation (taVNS) for Insomnia During the Withdrawal-Rehabilitation Period of Methamphetamine Use Disorder taVNS, sham-taVNS - Insomnia | Not applicable | Not yet recruiting | The First Affiliated Hospital of Zhejiang Chinese Medical University | 96 | 2026-10-01 | 2026-10-28 |
| Evaluating the Impact of Digital Behavioral Interventions to Address Insomnia and Depression in Breast Cancer Survivors Using an Adaptive Design Digital Insomnia Program, Digital Mental Health Program, Psychoeducation - Insomnia, Depression | Not applicable | Not yet recruiting | University of Virginia | 747 | 2026-09-30 | 2026-07-24 |
| Study on the Management of COMISA Daridorexant 50 mg, Continuous Positive Air Pressure (CPAP) - Obstructive Sleep Apnea (OSA), Insomnia | Not applicable | Recruiting | University Hospital, Grenoble | 150 | 2026-09-30 | 2026-10-05 |
| Deep Sleep in Older Adults SleepSpaceRx CBT-I-IoT-AI, SleepEZ CBTi, Sleep Hygiene IoT - Insomnia, Insomnia Chronic | Phase 2 | Recruiting | Proactive Life Inc | 180 | 2026-09-30 | 2026-10-20 |
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Sleep Initiation and Maintenance Disorders (1057) · Depression (129) · Anxiety Disorders (100) · Sleep Wake Disorders (82) · Parasomnias (56) · Fatigue (35) · Stress Disorders, Post-Traumatic (35) · Pain (29) · Neoplasms (28) · Chronic Pain (26) · Breast Neoplasms (23) · Cognitive Dysfunction (22) · Sleep Apnea, Obstructive (22) · Depressive Disorder, Major (19) · Psychological Well-Being (18)
Nervous System Diseases (1055) · Sleep Disorders, Intrinsic (1055) · Dyssomnias (1052) · Mental Disorders (1043) · Sleep Wake Disorders (975) · Pathological Conditions, Signs and Symptoms (234) · Signs and Symptoms (213) · Behavior (188) · Neurologic Manifestations (168) · Behavioral Symptoms (147) · Central Nervous System Diseases (68) · Brain Diseases (66) · Respiratory Tract Diseases (65) · Pathologic Processes (42) · Trauma and Stressor Related Disorders (42)
Cognitive Behavioral Therapy (149) · Eszopiclone (29) · Zolpidem (29) · suvorexant (28) · ramelteon (18) · lemborexant (11) · Acupuncture Therapy (10) · Melatonin (10) · Sleep (10) · Therapeutics (10) · Exercise (9) · Trazodone (9) · daridorexant (9) · Behavior Therapy (8) · Electroacupuncture (7)
The University of Hong Kong (33) · VA Office of Research and Development (28) · Brigham and Women's Hospital (16) · Chinese University of Hong Kong (16) · Karolinska Institutet (15) · Massachusetts General Hospital (14) · Stanford University (14) · The Hong Kong Polytechnic University (13) · Henry Ford Health System (12) · University of Pennsylvania (12) · Johns Hopkins University (11) · Merck Sharp & Dohme LLC (11) · University of Missouri-Columbia (11) · Sumitomo Pharma America, Inc. (9) · Taipei Medical University (9)
United States (481) · China (68) · Canada (56) · Hong Kong (55) · Sweden (35) · United Kingdom (30) · Taiwan (28) · France (23) · Netherlands (20) · Brazil (19) · Denmark (19) · Australia (16) · Spain (16) · Germany (15) · Norway (15)
Andrew Krystal, MD (4) · Ka-Fai Chung, MBBS (4) · Shirley Xin Li, PhD,DClinPsy (4) · Bin Zhang, MD & PhD (3) · Charles H Tegeler, MD (3) · Christopher Gordon, PhD (3) · Christopher Recklitis, PhD, MPH (3) · Jaap Lancee, PhD (3) · Lauren Asarnow, PhD (3) · Lianne Tomfohr-Madsen, PhD (3) · Michael L Perlis, PhD (3)
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2015 (5), 2023 (5), 2019 (2), 1IK2CX000855 (1), 1IK2RX001836-01A1 (1), 1UG3HL161342-01A1 (1), 2005 (1), 2016 (1), 2017 (1), 2018 (1), 2025 (1), 4RF1AG081520-02 (1), DP1OD003646 (1), F32AT006092 (1), F32NS049789 (1)