101 unknown. 101 Phase 3, 30 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 101 | Unknown 101 |
| Phase 2 | 30 | Unknown 30 |
Follow Inflammation: new trials by email Literature Review of Inflammation trials Research Report on Inflammation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Early Intravenous to Oral Antibiotic Switch in Uncomplicated Staphylococcus Aureus Bacteraemia Tab. Trimethoprim-sulfamethoxazole, Tab. Clindamycin, Tab. Cephalexin, or Tab. Linezolid, IV Cloxacillin, IV Cefazolin, IV Vancomycin, or IV Ceftaroline - Staphylococcus Aureus Bacteremia | Phase 3 | Unknown | Clinical Research Centre, Malaysia | 290 | 2024-06-28 | 2024-07-05 |
| Metformin and Lactoferrin in Sepsis in Icu Metformin, Lactoferrin - Sepsis | Phase 2 / Phase 3 | Unknown | Tanta University | 60 | 2024-04-01 | 2024-04-19 |
| Reversing Microvascular Dysfunction in Heart Failure With Preserved Ejection Fraction Colchicine, Placebo - Heart Failure With Preserved Ejection Fraction, Microvascular Coronary Artery Disease | Phase 2 / Phase 3 | Unknown | Montreal Heart Institute | 60 | 2024-03-01 | 2024-01-25 |
| MASLD Butyrate Supplementation Treatment Efficacy Review Sodium-Butyrate, Calcium Butyrate - MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease | Phase 3 | Unknown | University Medical Center Zvezdara | 200 | 2024-01-04 | 2025-01-06 |
| IMMUNERECOV CONTRIBUTES TO IMPROVEMENT OF RESPIRATORY AND IMMUNOLOGICAL RESPONSE IN POST-COVID-19 PATIENTS. Nutritional blend (ImmuneRecov). - Long Covid19, Dietary Supplements | Phase 3 | Unknown | Federal University of São Paulo | 58 | 2023-12-10 | 2023-12-12 |
| Effectiveness of Asiaticoside as Intracanal Medication on Infectious/Inflammatory Contents in Teeth With Apical Periodontitis Calcium Hydroxide Intracanal medication, Leddermix Intracanal medication, Asiaticoside Intracanal medication - Intracanal Medication | Phase 2 / Phase 3 | Unknown | Mansoura University | 36 | 2023-11-20 | 2024-08-22 |
| Clinical Evaluation of the Effect of Metformin in Sepsis Metformin - Sepsis | Phase 3 | Unknown | German University in Cairo | 110 | 2023-09-10 | 2023-09-13 |
| Adjunctive Esketamine for Analgesia in Mechanically Ventilated Septic Shock Patients Esketamine, Saline, Remifentanil + propofol - Septic Shock, Mechanical Ventilation Complication | Phase 3 | Unknown | Nanfang Hospital, Southern Medical University | 124 | 2023-05-31 | 2023-11-22 |
| Efficacy and Safety of corticoSTEROids Added to Standard Therapy in Patients With Acute Heart Failure (STERO-AHF) Dexamethasone, Prednisone - Acute Heart Failure | Phase 2 / Phase 3 | Unknown | Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia | 120 | 2023-04-24 | 2023-12-04 |
| Piperacillin-tazobactam and Temocillin as Carbapenem-alternatives for the Treatment of Severe Infections Due to Extended-spectrum Beta-lactamase-Producing Gram-negative Enterobacteriaceae in the Intensive Care Unit Piperacillin/tazobactam or temocillin, Meropenem - Sepsis, Septic Shock | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 600 | 2023-03-11 | 2023-04-18 |
| Alpha-Lipoic Acid in Patients With Sepsis Alpha-Lipoic Acid, Sepsis Supportive Care - Sepsis | Phase 2 / Phase 3 | Unknown | Ain Shams University | 60 | 2023-03-10 | 2023-04-12 |
| Dexmedetomidine and HIPEC Dexmedetomidine, Placebos - Inflammation, Cancer | Phase 2 / Phase 3 | Unknown | University of British Columbia | 20 | 2023-03-01 | 2022-11-03 |
| Colchicine Protective Effect in Patients Undergoing Percutaneous Coronary Intervention (COLCHICINE-PROTECT) Colchicine 0.5 MG Oral Tablet, Placebo - Coronary Artery Disease | Phase 3 | Unknown | Helwan University | 400 | 2023-03-01 | 2023-03-22 |
| Clobetasol Propionate Ophthalmic Nanoemulsion, 0.05% in the Treatment of Inflammation After Cataract Surgery in Pediatric Population Clobetasol Propionate, Prednisolone acetate ophthalmic suspension, 1% - Cataracts Infantile | Phase 3 | Unknown | Salvat | 60 | 2022-12-12 | 2024-09-27 |
| Effect of Melatonin in Pediatric Hemodialysis Patients Melatonin, Placebo - Hemodialysis Complication, Oxidative Stress | Phase 3 | Unknown | Ain Shams University | 40 | 2022-12-01 | 2023-01-31 |
| Clinical Trial Comparing Noradrenaline (NA) Plus Placebo Versus Noradrenaline Plus Terlipressin (TP) in Septic Shock Noradrenaline plus Terlipressin - Septic Shock | Phase 3 | Unknown | Fundación Pública Andaluza para la gestión de la Investigación en Sevilla | 152 | 2022-10-11 | 2023-04-27 |
| Impact of Aminoglycosides-based Antibiotics Combination and Protective Isolation on Outcomes in Critically-ill Neutropenic Patients With Sepsis: (Combination-Lock01) Aminoglycosides intervention, Lack of protective isolation intervention, No systematic aminoglycosides intervention - standard arm - Sepsis, Septic Shock | Phase 3 | Unknown | Assistance Publique - Hôpitaux de Paris | 340 | 2022-09-01 | 2022-07-05 |
| A Pilot Study of Antioxidant Therapy in Obstructive Sleep Apnea Patients Alpha Lipoic Acid 600 MG Oral Tablet, Placebo - Obstructive Sleep Apnea of Adult | Phase 2 / Phase 3 | Unknown | University of British Columbia | 80 | 2022-06-01 | 2022-05-25 |
| Enhanced Versus Extended Preoperative Antibiotic Prophylaxis Regimens for Retrograde Intrarenal Surgery in High Infectious Risk Patients Enhanced regimen, Extended regimen - Renal Stone | Phase 3 | Unknown | Mansoura University | 280 | 2022-05-01 | 2022-11-14 |
| PROlectin M, a Nucleocapsid TErminal GaleCTin Antagonist for COVID-19 Galactomannan, PLACEBO - COVID-19, COVID-19 Pandemic | Phase 3 | Unknown | Bioxytran Inc. | 408 | 2022-04-01 | 2022-03-09 |
Showing 20 of 101. Sign in to see all of them.
Sepsis (37) · Shock, Septic (19) · COVID-19 (12) · Cytokine Release Syndrome (8) · Neonatal Sepsis (6) · Pneumonia (5) · Shock (4) · Bacteremia (3) · Coronary Artery Disease (3) · Asthma (2) · Atherosclerosis (2) · Bronchopulmonary Dysplasia (2) · Cardiovascular Diseases (2) · Coronavirus Infections (2)
Pathologic Processes (101) · Pathological Conditions, Signs and Symptoms (101) · Infections (68) · Systemic Inflammatory Response Syndrome (57) · Shock (27) · Respiratory Tract Diseases (22) · Lung Diseases (18) · Respiratory Tract Infections (15) · Sepsis (14) · RNA Virus Infections (13) · Coronaviridae Infections (12) · Nidovirales Infections (12) · Pneumonia, Viral (12) · Virus Diseases (12)
Saline Solution (4) · Melatonin (3) · Metformin (3) · Standard of Care (3) · Thioctic Acid (3) · Acetylcysteine (2) · Chlorhexidine (2) · Colchicine (2) · Dexmedetomidine (2) · Doxycycline (2) · Heparin (2) · Ketamine (2) · Meropenem (2) · Methylene Blue (2) · Midazolam (2)
Cairo University (3) · University of Sao Paulo General Hospital (3) · Aga Khan University (2) · Ain Shams University (2) · Assistance Publique - Hôpitaux de Paris (2) · Hellenic Institute for the Study of Sepsis (2) · Mansoura University (2) · University of British Columbia (2) · Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) (1) · Alexandria University (1) · American British Cowdray Medical Center (1) · Aragon Institute of Health Sciences (1) · Augusta University (1) · Azienda Ospedaliera Universitaria Integrata Verona (1) · Azienda Ospedaliera di Padova (1)
Brazil (10) · China (10) · Egypt (10) · Italy (6) · United States (6) · Canada (5) · Spain (5) · France (4) · Iran (4) · Mexico (4) · Israel (3) · Netherlands (3) · Pakistan (3) · South Korea (3) · Australia (2)
Chien-Chang Lee, MD, MSc (2) · Ahmed Hasanin, Professor (1) · Ahmed Mukhtar, Professor (1) · Alaa Hemida (1) · Alfredo Aisa Alvarez, MD (1) · Alfredo R Zarate, MD (1) · Almas Aamir, MSC (1) · Amany Bader, prof (1) · Amir Vahedian-Azimi, PhD (1) · Amr A Elsawy (1) · Andrew C Miller, MD (1) · Anita KM Zaidi, MBBS, SM (1) · Anna Taddio, PhD (1) · Araceli Montoya-Estrada, PhD (1) · Arash Shirvani, MD, PhD (1)
PMID 12628952, PMID 1342820, PMID 18289548, PMID 19846212, PMID 20373128, PMID 21187189, PMID 21458008, PMID 22565291, PMID 22869824, PMID 23562296, PMID 24099368, PMID 24289974, PMID 24669841, PMID 24675228, PMID 25104975, PMID 25272316, PMID 25511715, PMID 25986785, PMID 26063507, PMID 26431839, PMID 27626473, PMID 27770787, PMID 28042707, PMID 28606823, PMID 28676917, PMID 29299402, PMID 29772657, PMID 30184183, PMID 30660196, PMID 30845690, PMID 30985391, PMID 31285784, PMID 31333648, PMID 31492102, PMID 31733140, PMID 32227755, PMID 32295417, PMID 32418846, PMID 32865380, PMID 33006765, PMID 33153629, PMID 33534419, PMID 33574139, PMID 33673929, PMID 33704071, PMID 33744748, PMID 33757717, PMID 33804999, PMID 33972949, PMID 34003667
2009 (1), 2017 (1), 2018 (1), K08HD052885 (1), P30CA138292 (1), R01HL131674 (1), R44DK059062 (1)