18 withdrawn. 18 Phase 1, 11 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 18 | Withdrawn 18 |
| Phase 2 | 11 | Withdrawn 11 |
Follow Inflammation: new trials by email Literature Review of Inflammation trials Research Report on Inflammation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pre-emptive Anakinra for Cytokine Event Reduction Anakinra (Kineret®) - B-Acute Lymphoblastic Leukemia, CAR-T Cell Therapy | Phase 1 / Phase 2 | Withdrawn | Kevin McNerney | 2026-10-01 | 2026-08-13 | |
| Rezafungin Pharmacokinetics in Patients on ECMO Rezafungin - Sepsis | Phase 1 | Withdrawn | Hartford Hospital | 2024-07-01 | 2024-12-17 | |
| Targeting Senescence to Reduce Osteoarthritis Pain and cartilagE Breakdown (ROPE) High-dose/short-duration Fisetin, Low-dose/sustained-duration Fisetin, Oral placebo capsule - Osteoarthritis, Knee | Phase 1 / Phase 2 | Withdrawn | Austin V Stone | 2023-06-01 | 2022-07-29 | |
| CORONA: A Study Using DeltaRex-G Gene Therapy for Symptomatic COVID-19 DeltaRex-G - COVID-19, Cytokine Storm | Phase 1 / Phase 2 | Withdrawn | Aveni Foundation | 2022-12-12 | 2025-02-24 | |
| Immunomodulation Using VB-201 to Reduce Arterial Inflammation in Treated HIV - VITAL HIV Trial VB-201, Placebo - Inflammation, HIV Infection | Phase 1 / Phase 2 | Withdrawn | Priscilla Hsue, MD | 2022-07-01 | 2022-09-15 | |
| NAC Treatment and Outcomes in Patients With Advanced Atherosclerosis and DM N-acetylcysteine, Placebo - Atherosclerosis of Artery, Peripheral Artery Disease | Phase 1 | Withdrawn | University of Missouri-Columbia | 2021-10-15 | 2023-06-18 | |
| SHIFT: Studying HIV Immunology After Fecal Transplant Fecal Inoculum Capsule, Placebo (for Fecal Inoculum Capsule), Antibiotic - HIV/AIDS, Dysbiosis | Phase 1 / Phase 2 | Withdrawn | Massachusetts General Hospital | 2018-06-01 | 2018-11-15 | |
| Minocycline for Alcohol Use Disorder Minocycline, Sugar pill - Alcohol Use Disorder, Inflammation | Phase 1 / Phase 2 | Withdrawn | University of California, Los Angeles | 2018-01-15 | 2019-01-24 | |
| Dose Assessment of Melatonin in Sepsis Trial Melatonin - Sepsis | Phase 1 / Phase 2 | Withdrawn | University of Aberdeen | 2017-04-01 | 2017-04-21 | |
| Thiamine Supplementation in Patients With Septic Shock Thiamine, Placebos - Septic Shock, Shock, Septic | Phase 1 | Withdrawn | The Cleveland Clinic | 2016-11-05 | 2019-03-15 | |
| Pharmacology of Exenatide in Pediatric Sepsis Exenatide, Exenatide vehicle - Septic Shock, Inflammation | Phase 1 / Phase 2 | Withdrawn | Seattle Children's Hospital | 2012-10-01 | 2017-10-05 | |
| The Role of Prostaglandins in the Progression of Diabetic Retinopathy Acuvail, Placebo - Inflammation | Phase 1 | Withdrawn | Vanderbilt University | 2012-03-01 | 2017-02-23 | |
| Use of Azithromycin as Immunomodulatory Therapy in Grave&Apos;s Orbitopathy Azithromycin - Graves Ophthalmopathy | Phase 1 / Phase 2 | Withdrawn | Rabin Medical Center | 2011-05-01 | 2017-04-27 | |
| Pharmacokinetics and Safety of Ticarcillin-clavulanate in Infants Ticarcillin-clavulanic acid - Sepsis | Phase 1 | Withdrawn | Phillip Brian Smith | 2010-09-01 | 2012-11-14 | |
| An Investigation of NNC 0151-0000-0000 in Subjects With Systemic Lupus Erythematosus (SLE) NNC 0151-0000-0000, placebo - Inflammation, Systemic Lupus Erythematosus | Phase 1 | Withdrawn | Novo Nordisk A/S | 2009-11-01 | 2014-08-15 | |
| A Study on the Tolerability and Early Efficacy of hLF1-11 in Patients With Bacteremia Due to S. Epidermidis human lactoferrin peptide 1-11 - Staphylococcal Infections, Bacteremia | Phase 1 / Phase 2 | Withdrawn | AM-Pharma | 2009-02-01 | 2014-05-28 | |
| A Study on the Tolerability and Early Efficacy of hLF1-11 in Patients With Proven Candidaemia hLF1-11, Placebo - Candidaemia | Phase 1 / Phase 2 | Withdrawn | AM-Pharma | 2008-07-01 | 2015-06-30 | |
| Inflammatory Response and Pregnancy Outcome in Women With Type 2 Diabetes or Overweight physical activity - Inflammation | Phase 1 | Withdrawn | Copenhagen University Hospital, Rigshospitalet | 280 | 2006-03-01 | 2007-08-21 |
Sepsis (4) · Cytokine Release Syndrome (2) · Shock, Septic (2) · Acidosis, Lactic (1) · Acquired Immunodeficiency Syndrome (1) · Alcohol Drinking (1) · Alcoholism (1) · Atherosclerosis (1) · Bacteremia (1) · Burkitt Lymphoma (1) · COVID-19 (1) · Candidemia (1) · Cardiovascular Diseases (1) · Cognition Disorders (1)
Pathologic Processes (18) · Pathological Conditions, Signs and Symptoms (18) · Infections (11) · Systemic Inflammatory Response Syndrome (9) · Immune System Diseases (5) · Shock (4) · Virus Diseases (4) · RNA Virus Infections (3) · Sepsis (3) · Autoimmune Diseases (2) · Bacterial Infections and Mycoses (2) · Blood-Borne Infections (2) · Communicable Diseases (2) · Endocrine System Diseases (2)
lactoferrin (1-11), human (2) · 1-palmityl-2-(4-carboxybutyl)-sn-glycero-3-phosphocholine (1) · Acetylcysteine (1) · Anti-Bacterial Agents (1) · Azithromycin (1) · Exenatide (1) · Exercise (1) · Glucose (1) · Interleukin 1 Receptor Antagonist Protein (1) · Ketorolac (1) · Melatonin (1) · Minocycline (1) · Rezafungin (1) · Sugars (1) · Thiamine (1)
AM-Pharma (2) · Austin V Stone (1) · Aveni Foundation (1) · Copenhagen University Hospital, Rigshospitalet (1) · Hartford Hospital (1) · Kevin McNerney (1) · Massachusetts General Hospital (1) · Novo Nordisk A/S (1) · Phillip Brian Smith (1) · Priscilla Hsue, MD (1) · Rabin Medical Center (1) · Seattle Children's Hospital (1) · The Cleveland Clinic (1) · University of Aberdeen (1) · University of California, Los Angeles (1)
United States (8) · Netherlands (2) · China (1) · Denmark (1) · United Kingdom (1)
Professor P.E. Verweij, MD, PhD (2) · Austin Stone, MD, PhD (1) · Bettina Breitowicz, MD (1) · Douglas Kwon, MD, PhD (1) · Hadas Kalish, MD (1) · Helen Galley (1) · Jinesh Mehta, MD (1) · Joseph L. Kuti, PharmD (1) · Priscilla Hsue, MD (1) · Sant P Chawla, MD (1) · Stephen J Kim, MD (1)
PMID 22871833, PMID 24264034, PMID 24336915
K01AA026005 (1), K12TR005104 (1)