2 active not recruiting, 2 completed, 2 terminated, 1 enrolling by invitation. 3 Phase 1, 3 Phase 3, 2 Phase 2, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 1 | 3 | Terminated 2, Withdrawn 1 |
| Phase 3 | 3 | Completed 2, Enrolling by invitation 1 |
| Phase 2 | 2 | Active not recruiting 1, Recruiting 1 |
| Phase 4 | 1 | Active not recruiting 1 |
Follow Rezafungin: new trials by email Literature Review of Rezafungin trials Research Report on Rezafungin
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Pharmacokinetic Study of Rezafungin in Patients With Suspected Intra-Abdominal Candidiasis Rezafungin 400mg followed by weekly doses of intravenous Rezafungin 200mg - Candidal Peritonitis | Phase 4 | Active not recruiting | Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal | 20 | 2026-01-07 | 2026-09-16 |
| Rezafungin Prophylaxis in Liver Transplant Rezafungin, Standard of care antifungal prophylaxis - Liver Transplant Infection, Fungal Infection | Phase 3 | Enrolling by invitation | Fernanda P Silveira, MD, MS | 385 | 2025-10-15 | 2026-09-29 |
| Rezafungin for Treatment of Chronic Pulmonary Aspergillosis (CPA) in Adults With Limited Treatment Options Rezafungin Acetate - Chronic Pulmonary Aspergillosis | Phase 2 | Active not recruiting | Mundipharma Research Limited | 60 | 2025-06-30 | 2026-05-14 |
| Rezafungin Pharmacokinetics in Patients on ECMO Rezafungin - Sepsis | Phase 1 | Withdrawn | Hartford Hospital | 2024-07-01 | 2024-12-17 | |
| Rezafungin for Treatment of Pneumocystis Pneumonia in HIV Adults Co-Trimoxazole, Rezafungin Acetate / Co Trimoxazole - Pneumocystis Pneumonia | Phase 2 | Recruiting | Mundipharma Research Limited | 50 | 2023-11-14 | 2025-04-03 |
| Rezafungin Paediatric PK Study in Paediatric Subjects From Birth to <18 Years of Age Rezafungin Acetate - Invasive Fungal Infections | Phase 1 | Terminated | Mundipharma Research Limited | 32 | 2023-09-13 | 2025-04-06 |
| Study of Rezafungin Compared to Standard Antimicrobial Regimen for Prevention of Invasive Fungal Diseases in Adults Undergoing Allogeneic Blood and Marrow Transplantation Rezafungin for Injection, Posaconazole, Fluconazole - Candidemia, Mycoses | Phase 3 | Completed | Mundipharma Research Limited | 602 | 2020-05-11 | 2026-04-13 |
| Safety and Pharmacokinetics of Rezafungin Placebo, Rezafungin - Fungal Infection | Phase 1 | Terminated | National Institute of Allergy and Infectious Diseases (NIAID) | 14 | 2019-12-04 | 2021-07-16 |
| Study of Rezafungin Compared to Caspofungin in Subjects With Candidemia and/or Invasive Candidiasis Rezafungin for Injection, Caspofungin, Fluconazole - Candidemia, Mycoses | Phase 3 | Completed | Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) | 199 | 2018-10-07 | 2023-01-06 |
Mycoses (4) · Invasive Fungal Infections (3) · Sepsis (3) · Candidemia (2) · Candidiasis (2) · Candidiasis, Invasive (2) · Fungemia (2) · Pathologic Processes (2) · Pneumonia, Pneumocystis (2) · Systemic Inflammatory Response Syndrome (2) · Infections (1) · Inflammation (1)
Mundipharma Research Limited (4) · Cidara Therapeutics Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA) (1) · Fernanda P Silveira, MD, MS (1) · Fundacion para la Investigacion Biomedica del Hospital Universitario Ramon y Cajal (1) · Hartford Hospital (1) · National Institute of Allergy and Infectious Diseases (NIAID) (1)
Spain (5) · Germany (4) · United States (4) · Belgium (3) · France (3) · Italy (3) · United Kingdom (3) · South Korea (2) · Argentina (1) · Australia (1) · Austria (1) · Bulgaria (1) · Canada (1) · China (1) · Colombia (1)
Fernanda Silveira (1) · Joseph L. Kuti, PharmD (1) · Laura Cox, PhD (1) · Mohit Joshi, MD (1) · Taylor Sandison, MD, MPH (1)
PMID 33438477, PMID 36442484, PMID 37773627, PMID 38008099, PMID 38502709, PMID 38985561, PMID 39259571, PMID 39468640, PMID 39529079, PMID 41151592, PMID 41194465, PMID 41940006
2017 (1)