7 completed, 7 unknown, 5 active not recruiting, 3 terminated. 11 Not applicable, 4 Phase 3, 2 Phase 2, 1 Early Phase 1, 1 Phase 4.
Follow Idiopathic Intracranial Hypertension: new trials by email Literature Review of Idiopathic Intracranial Hypertension trials Research Report on Idiopathic Intracranial Hypertension
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Idiopathic Intracranial Hypertension: Prognostic Factors and Multidisciplinary Management lumbo-peritoneal shunt, Conservative Management: Centered on lifestyle modifications for weight reduction, alongside targeted medical therapies including carbonic anhydrase inhibitors (e.g., acetazolamide) and/or topiramate. - Idiopathic Intracranial Hypertension | Not applicable | Active not recruiting | Sohag University | 30 | 2026-06-01 | 2026-07-21 |
| Disease Biosignatures in ALS/FTD Spectrum: New Impactful Biological Perspectives Beyond Clinical Approaches ALS (Amyotrophic Lateral Sclerosis), FTD | Active not recruiting | Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta | 230 | 2025-02-27 | 2026-08-28 | |
| Prospective Ocular Imaging for Intracranial Pressure Evaluation Idiopathic Intracranial Hypertension, Intracranial Pressure Increase | Recruiting | King's College Hospital NHS Trust | 160 | 2025-01-10 | 2025-08-03 | |
| ICP & Outflow Study Lumbar puncture - Eye Change, Idiopathic Intracranial Hypertension | Unknown | Guy's and St Thomas' NHS Foundation Trust | 66 | 2024-06-01 | 2024-06-12 | |
| Ocular Perfusion in Patients With Idiopathic Intracranial Hypertension Lumbar puncture and administration of medication - Idiopathic Intracranial Hypertension | Unknown | Medical University of Vienna | 48 | 2024-05-28 | 2024-08-30 | |
| Exploratory Study on the Efficacy and Safety of Semaglutide for Idiopathic Intracranial Hypertension Treatment Semaglutide, Low calorie diet - Idiopathic Intracranial Hypertension | Phase 3 | Unknown | Capital Medical University | 74 | 2024-05-01 | 2024-04-12 |
| Biomarkers in the Etiology of Idiopathic Intracranial Hypertension Blood punction, Central blood sampling, Intracranial pressure measurement - Idiopathic Intracranial Hypertension | Not applicable | Unknown | University Hospital, Montpellier | 60 | 2023-11-27 | 2024-05-28 |
| MR Lymphatic Imaging in Idiopathic Intracranial Hypertention 3T MRI with Gadobutrol injection - Idiopathic Intracranial Hypertension | Not applicable | Completed | Institut National de la Santé Et de la Recherche Médicale, France | 40 | 2023-03-10 | 2026-10-08 |
| A Trial to Determine the Efficacy and Safety of Presendin in IIH Presendin, Placebo - Idiopathic Intracranial Hypertension | Phase 3 | Terminated | Invex Therapeutics Ltd. | 14 | 2022-11-18 | 2024-04-24 |
| The Effect of an Anti-obesity Drug, Semaglutide, as Treatment in New-onset Idiopathic Intracranial Hypertension (IIH) Compared to Standard Weight Management (Dietician) With Regards to Change in Weight and Intracranial Pressure Semaglutide, Very Low Calorie Diet, Dietician counselling - Idiopathic Intracranial Hypertension, Intracranial Pressure | Phase 4 | Completed | Rigmor Højland Jensen | 38 | 2022-09-02 | 2026-02-27 |
| Outcome of Cerebral Venous Sinuses Stenting on Idiopathic Intracranial Hypertension Stent - Idiopathic Intracranial Hypertension | Not applicable | Unknown | Al-Azhar University | 20 | 2022-03-15 | 2022-04-04 |
| Assessment of ICP in Idiopathic Intracranial Hypertension Using Transocular Ultrasound and Transcranial Doppler TOS and TCD - Idiopathic Intracranial Hypertension | Not applicable | Completed | Danish Headache Center | 78 | 2020-01-01 | 2023-03-07 |
| The Effects of MAP and EtCO2 on Venous Sinus Pressures Venous Sinus Stenting, Adjustment to end-tidal carbon dioxide concentrations ( 38-40 mmHg range), Adjustment to Mean Arterial Pressure (100-110 mmHg range) - Idiopathic Intracranial Hypertension | Not applicable | Completed | Wake Forest University Health Sciences | 8 | 2019-06-20 | 2020-05-12 |
| Surgical Idiopathic Intracranial Hypertension Treatment Trial Acetazolamide, Optic Nerve Sheath Fenestration, Ventriculoperitoneal CSF Shunting - Idiopathic Intracranial Hypertension | Phase 3 | Terminated | Jaeb Center for Health Research | 7 | 2019-02-06 | 2022-06-16 |
| Venous Sinus Stenting With the River Stent in IIH Venous sinus stenting (Serenity River) - Idiopathic Intracranial Hypertension | Not applicable | Active not recruiting | Serenity Medical, Inc. | 39 | 2018-08-24 | 2023-06-22 |
| Quantitative D-dimer Level and Anticoagulant Therapy in Idiopathic Intracranial Hypertension LMWH, acetazolamide - Idiopathic Intracranial Hypertension | Early Phase 1 | Completed | Fayoum University | 48 | 2017-07-22 | 2019-05-24 |
| Evaluating Raised Intracranial Pressure Using MR Elastography MR elastography, MRI structural brain imaging, Lumbar puncture - Idiopathic Intracranial Hypertension | Not applicable | Active not recruiting | Mayo Clinic | 200 | 2017-01-10 | 2026-03-04 |
| Astronaut Vision Issues in a Ground Analog Population: Polycystic Ovary Syndrome Polycystic Ovarian Syndrome, Idiopathic Intracranial Hypertension | Active not recruiting | National Aeronautics and Space Administration | 60 | 2016-10-01 | 2025-05-22 | |
| Comparison of Continuous Non-Invasive and Invasive Intracranial Pressure Measurement Tympanic membrane displacement (TMD), DPOAE - Hydrocephalus, Idiopathic Intracranial Hypertension | Not applicable | Terminated | LifeBridge Health | 5 | 2014-09-01 | 2017-08-11 |
| Safety and Effectiveness of 11b-Hydroxysteroid Dehydrogenase Type 1 Inhibitor (AZD4017) to Treat Idiopathic Intracranial Hypertension. AZD4017, Placebo - Idiopathic Intracranial Hypertension | Phase 2 | Completed | University of Birmingham | 31 | 2014-04-25 | 2021-10-27 |
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Pseudotumor Cerebri (23) · Headache (5) · Intracranial Hypertension (4) · Papilledema (4) · Obesity (3) · Vision Disorders (3) · Tinnitus (2) · Weight Loss (2) · Amyotrophic Lateral Sclerosis (1) · Blindness (1) · Diplopia (1) · Frontotemporal Dementia (1) · Hydrocephalus (1) · Mental Disorders (1) · Polycystic Ovary Syndrome (1)
Brain Diseases (23) · Central Nervous System Diseases (23) · Nervous System Diseases (23) · Intracranial Hypertension (19) · Pathological Conditions, Signs and Symptoms (7) · Signs and Symptoms (7) · Eye Diseases (6) · Neurologic Manifestations (5) · Pain (5) · Body Weight (4) · Cranial Nerve Diseases (4) · Nutritional and Metabolic Diseases (4) · Optic Nerve Diseases (4) · Sensation Disorders (4) · Nutrition Disorders (3)
Acetazolamide (4) · Spinal Puncture (3) · semaglutide (2) · 2-(1-(5-(cyclohexylcarbamoyl)-6-propylsulfanylpyridin-2-yl)-3-piperidyl)acetic acid (1) · Acetaminophen (1) · Aspirin (1) · Bariatric Surgery (1) · Caloric Restriction (1) · Codeine (1) · Diagnostic Imaging (1) · Diuretics (1) · Heparin, Low-Molecular-Weight (1) · Ibuprofen (1) · Naproxen (1) · Stents (1)
University of Birmingham (2) · Al-Azhar University (1) · Capital Medical University (1) · Danish Headache Center (1) · Fayoum University (1) · Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta (1) · Guy's and St Thomas' NHS Foundation Trust (1) · Institut National de la Santé Et de la Recherche Médicale, France (1) · Invex Therapeutics Ltd. (1) · Jaeb Center for Health Research (1) · King's College Hospital NHS Trust (1) · LifeBridge Health (1) · Mayo Clinic (1) · Medical University of Vienna (1) · National Aeronautics and Space Administration (1)
United States (8) · United Kingdom (4) · Canada (3) · Egypt (3) · Denmark (2) · France (2) · Australia (1) · Austria (1) · Germany (1) · Israel (1) · Italy (1) · New Zealand (1) · Puerto Rico (1)
Michael Wall, MD (2) · Alexandra Sinclair, MBChB (1) · Alexandra Sinclair, MbChb PhD (1) · Alice Y Chang, MD (1) · Athos Patsalides, MD (1) · John J Chen, M.D., Ph.D. (1) · Kyle Fargen, MD (1) · Michael A. Williams, MD (1) · Mohammed Ahmed Zaki, Ass. Prof (1) · Rigmor H Jensen, Professor (1) · Rigmor Jensen, Dr.med. (1) · Scott M Smith, PhD (1)
PMID 36240084, PMID 21323404, PMID 21799038, PMID 24756302, PMID 24756514, PMID 24781936, PMID 25370510, PMID 25370513, PMID 25859134, PMID 26024112, PMID 26335066, PMID 26618282, PMID 26778344, PMID 26934136, PMID 27556959, PMID 27694262, PMID 27886896, PMID 28130349, PMID 28255904, PMID 28492874, PMID 28923789, PMID 28963303, PMID 33098644, PMID 33900360, PMID 34420064, PMID 34620087, PMID 35790425, PMID 37740611, PMID 42487032
U10EY025990 (2), U10EY017281 (1), U10EY017387 (1)