63 completed, 41 unknown, 18 recruiting, 14 terminated. 37 Phase 3, 30 Not applicable, 30 Phase 4, 16 Phase 2, 7 Phase 1.
Follow Heparin, Low-Molecular-Weight: new trials by email Literature Review of Heparin, Low-Molecular-Weight trials Research Report on Heparin, Low-Molecular-Weight
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Efficacy of Progesterone and Low Molecular Weight Heparin in Recurrent Miscarriages Vaginal micronized progesterone, Enoxaparin (LMWH) - Pregnancy Loss, Pregnancy Loss, Early | Phase 3 | Not yet recruiting | General University Hospital, Prague | 264 | 2026-12-01 | 2026-09-09 |
| Comparison of DOACs and LMWH for Thromboprophylaxis After Total Knee Arthroplasty Apixaban, Rivaroxaban, Enoxaparin (LMWH) - Total Knee Arthroplasty, Venous Thromboembolism | Not applicable | Recruiting | Military Hospital of Tunis | 138 | 2026-09-15 | 2026-10-16 |
| Adaptive Platform Trial for Personnalisation of Sepsis Treatment in Children and Adults: a Multi-national, Treatable Traits-guided, Adaptive, Exploratory, Bayesian Basket Trial Tocilizumab, Baricitinib, Anakinra - Sepsis | Phase 2 | Recruiting | Assistance Publique - Hôpitaux de Paris | 2000 | 2026-07-09 | 2026-10-20 |
| Delivery and Implementation of a Randomised Crossover Trial on Thrombosis Patients in hospitals allocated to this arm will receive aspirin as their routine thromboprophylaxis after surgery., Low molecular weight heparin (LMWH) - Hip Fractures, Venous Thromboembolism (VTE) | Not applicable | Recruiting | Queen Mary University of London | 21194 | 2026-07-01 | 2026-09-23 |
| Percutaneous Embolectomy, Low Dose Thrombolysis or Heparin for Intermediate High Risk Pulmonary Embolism (STRATIFY II) Ultrasound assisted Thrombolysis, Percutaneous Embolectomy, Heparin - Pulmonary Embolism | Phase 3 | Recruiting | Jesper Kjaergaard | 210 | 2026-06-17 | 2026-07-02 |
| The PARTUM Trial: Postpartum Aspirin to Reduce Thromboembolism Undue Morbidity Aspirin, Low-molecular-weight heparin - Venous Thromboembolism, Postpartum Period | Phase 3 | Recruiting | University of Calgary | 8805 | 2026-06-04 | 2026-07-27 |
| Optimizing Anticoagulation in Pregnancies With Mechanical Heart Valves LMWH and LDA, Vitamin K antagonists (e.g warfarin)+/- LDA, Sequential therapy +/- LDA - Pregnancy, Prosthetic Heart Valve | Not applicable | Recruiting | Mount Sinai Hospital, Canada | 100 | 2026-05-26 | 2026-06-22 |
| Adding Evolocumab to Conventional Lipid-lowering Therapy for Hypertriglyceridemia Induced Acute Pancreatitis Evolocumab 140 MG/ML [Repatha], Conventional lipid-lowering therapy - Hypertriglyceridemia Induced Acute Pancreatitis | Not applicable | Recruiting | General Hospital of Shenyang Military Region | 60 | 2026-01-02 | 2026-09-25 |
| Short-term Low-dose Low-molecular-weight Heparin to Prevent Postpartum Thrombosis Low-dose low-molecular-weight heparin - Venous Thromboembolism (VTE), Postpartum | Phase 3 | Recruiting | Marc Blondon | 9200 | 2025-10-15 | 2026-10-06 |
| TRiP-cast Score Validation and Evaluation of Adherence to Preventive Anticoagulant Treatment in Patients With Lower Limb Trauma Requiring Immobilization Low-Molecular-Weight Heparin (LMWH), Direct Oral Anticoagulants (DOACs), No Thromboprophylaxis Cohort - Lower Extremity Injuries, Venous Thromboembolism (VTE) | Recruiting | University of Monastir | 1500 | 2025-09-01 | 2026-10-07 | |
| The Intensive Care Platform Trial Albumin, No albumin use, LMWH in weight-adjusted dose - Intensive Care Patients, Intensive Care Unit Patients | Phase 4 | Recruiting | Anders Perner | 10000 | 2025-06-26 | 2026-10-05 |
| Prevention of Postpartum Venous Thromboembolism in Women at Intermediate Risk Low molecular weight heparin - Venous Thromboembolism (VTE), Post Partum Women | Phase 4 | Recruiting | University Hospital, Brest | 2400 | 2025-05-16 | 2026-06-10 |
| Timing of Thromboprophylaxis After Postpartum Hemorrhage Pharmacologic Thromboprophylaxis - Postpartum Hemorrhage, Venous Thromboembolism | Completed | University Tunis El Manar | 236 | 2025-03-01 | 2026-07-08 | |
| Predictive Value of Modified Caprini Score and D-Dimer in Managing Lower Limb Venous Thrombosis in Cardiothoracic Patients GCS, LMWH - DVT - Deep Vein Thrombosis | Recruiting | Al-Nahrain University | 112 | 2025-01-20 | 2026-09-17 | |
| Reduced-Dose Apixaban and Rivaroxaban Versus Low-Molecular-Weight Heparin in Patients With Hematologic Malignancies Apixaban, Rivaroxaban, low molecular weight heparin (enoxaparin sodium) - Lymphoma, Leukemia | Not applicable | Recruiting | Medical University of Gdansk | 100 | 2024-11-22 | 2025-12-26 |
| A Multicenter, Open-Label, Non-Inferiority Randomized Controlled Trial of Postoperative VTE Prevention in Chinese Patients After Colorectal Cancer Surgery Low Molecular Weight Heparin (dalteparin) - Colorectal Surgery, VTE (Venous Thromboembolism) | Not applicable | Not yet recruiting | Beijing Friendship Hospital | 1448 | 2024-10-01 | 2024-09-04 |
| The Gynecological Cancer Associated Thrombosis (GynCAT) Study Anticoagulant - Cancer-associated Thrombosis, Venous Thromboembolism | Unknown | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 1800 | 2024-04-15 | 2024-09-19 | |
| A Study of the Efficacy of Troxerutin in Preventing Thrombotic Events in COVID-19 Patients Troxerutin, Placebo, placebo + low molecular weight heparin - COVID 19 Associated Coagulopathy | Phase 1 | Recruiting | Westlake University | 80 | 2023-12-15 | 2024-11-12 |
| Role of Low-Molecular-Weight Heparin in Unexplained Recurrent Pregnancy Loss Low molecular weight heparin - Pregnancy Loss | Not applicable | Completed | RESnTEC, Institute of Research | 175 | 2023-12-01 | 2024-07-03 |
| LDA and LMWH vs LDA Alone in High-risk Patients for Preeclampsia Prevention Aspirin, Tinzaparin - Preeclampsia Severe, Toxemia Of Pregnancy | Phase 4 | Recruiting | Alexandra Hospital, Athens, Greece | 100 | 2023-01-18 | 2026-01-23 |
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Venous Thromboembolism (31) · Venous Thrombosis (30) · Pulmonary Embolism (24) · Thrombosis (14) · COVID-19 (11) · Neoplasms (11) · Thromboembolism (5) · Hemorrhage (4) · Infertility (4) · Abortion, Habitual (3) · Acute Coronary Syndrome (3) · Fibrosis (3) · Hemostatic Disorders (3) · Multiple Myeloma (3) · Pneumonia (3)
Ain Shams University (4) · Bayer (4) · McMaster University (4) · Mount Sinai Hospital, Canada (3) · AHEPA University Hospital (2) · Assistance Publique - Hôpitaux de Paris (2) · Azidus Brasil (2) · Azienda Ospedaliera Universitaria Policlinico (2) · Capital Medical University (2) · Daiichi Sankyo (2) · Pirogov Russian National Research Medical University (2) · Qilu Hospital of Shandong University (2) · Quovadis Associazione (2) · RenJi Hospital (2) · Shahid Beheshti University of Medical Sciences (2)
China (27) · Canada (17) · United States (17) · Germany (15) · Italy (13) · Netherlands (11) · United Kingdom (11) · France (10) · Brazil (7) · Denmark (7) · Egypt (7) · Greece (7) · Spain (7) · Austria (6) · Israel (5)
Dou-Sheng Bai, MD (2) · Guo-Qing Jiang, MS (2) · Hamid Ahmadieh, MD (2) · Kirill Lobastov, PhD (2) · Leslie Skeith, MD (2) · Marc Rodger, MD (2) · Ping Chen, MD (2) · Sergio Siragusa, MD (2) · Suzanne C Cannegieter, PhD, MD (2) · Aimin Zhao, MD (1) · Alexandre Frederico (1) · Anders Granholm, MD (1) · Anders Perner, Professor (1)
PMID 35244208, PMID 32358837, PMID 15842354, PMID 27959702, PMID 33502773, PMID 37591523, PMID 10453824, PMID 10546719, PMID 10632428, PMID 10648016, PMID 10927736, PMID 12090565, PMID 12387283, PMID 12709915, PMID 12763484, PMID 12825542, PMID 15132746, PMID 15383488, PMID 16287790, PMID 16368644, PMID 16716321, PMID 16926353, PMID 17075810, PMID 17487675, PMID 1750226, PMID 17556722, PMID 1757934, PMID 17646239, PMID 18248600, PMID 18278191, PMID 18572147, PMID 18667193, PMID 18824906, PMID 18827132, PMID 19029477, PMID 19242322, PMID 19357135, PMID 19390908, PMID 19439078, PMID 19682670, PMID 19878532, PMID 1989784, PMID 19959589, PMID 20447951, PMID 20528832, PMID 20626619, PMID 21112094, PMID 21315207, PMID 21315215, PMID 21417952
2014 (1), 2015 (1), 2016 (1), 2017 (1), 2019 (1), 2023 (1), 2025 (1), R01NR008937 (1)