129 completed, 23 recruiting, 11 active not recruiting, 7 terminated. 61 Not applicable, 55 Phase 3, 22 Phase 2, 10 Phase 4, 6 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| A Randomized Trial of Botulinum Toxin A vs Strabismus Surgery for Esotropia >10 to ≤30PD Botulinum toxin A, bilateral medial rectus recession - Esotropia | Phase 3 | Not yet recruiting | Jaeb Center for Health Research | 244 | 2027-01-01 | 2026-04-06 |
| Omega-3 Supplementation vs Demodex vs Eyelid Cleanser for Pediatric Chalazia Omega-3 supplement, Warm compress, Standard eyelid cleanser - Pediatric Chalazia | Phase 2 | Not yet recruiting | Jaeb Center for Health Research | 168 | 2026-10-01 | 2026-08-25 |
| Longitudinal Study of Retinal Function in Eyes Treated for Diabetic Macular Edema With Anti-VEGF Agents Anti-Vascular Endothelial Growth Factor - Diabetic Retinal Disease | Phase 4 | Recruiting | Jaeb Center for Health Research | 100 | 2026-07-31 | 2026-09-18 |
| A RCT of Spectacles With Aspherical Lenslets or 0.05% Atropine for Myopia Control Atropine, Spectacles with HAL, Placebo Eyedrops - Myopia | Phase 3 | Recruiting | Jaeb Center for Health Research | 348 | 2026-06-01 | 2026-06-26 |
| Longitudinal Natural History Study of Retinal Function in Eyes of Patients With Diabetes Visual Acuity, Reading Speed, Visual Field testing - Diabetic Retinal Disease | Recruiting | Jaeb Center for Health Research | 450 | 2026-06-01 | 2026-09-16 | |
| Safety Evaluation of MODI, an Insulin Titration Algorithm, in Adults With Diabetes MODI Algorithm - Type 1 Diabetes (T1D), Type 2 Diabetes (T2D) | Not applicable | Recruiting | DreaMed Diabetes | 102 | 2026-05-25 | 2026-08-28 |
| Evaluation of the Fully Closed Loop Omnipod® System in Type 2 Diabetes Device: Omnipod M System with study CGM, Standard Therapy plus study CGM - Type 2 Diabetes Mellitus | Not applicable | Recruiting | Insulet Corporation | 350 | 2026-04-30 | 2026-08-03 |
| A Study of Uveitis in Children <18 Years of Age Uveitis | Recruiting | Jaeb Center for Health Research | 300 | 2026-04-14 | 2026-05-08 | |
| Safety and Efficacy of Adjunct Therapies in Adults With Type 1 Diabetes: Multicenter, Registry Study Type 1 Diabetes | Recruiting | Indiana University | 300 | 2026-03-24 | 2026-10-16 | |
| A Randomized Phase 1/2 Trial of Low Dose Anti-thymocyte Globulin (ATG) With Subsequent Adalimumab or Verapamil in New Onset Type 1 Diabetes Anti-thymocyte globulin (ATG), verapamil extended-release capsule, Adalimumab - Type 1 Diabetes, New Onset | Phase 1 / Phase 2 | Recruiting | City of Hope Medical Center | 120 | 2026-03-10 | 2026-10-16 |
| INHALE-1st: Afrezza® For Youth With Newly-Diagnosed Type 1 Diabetes Technosphere Insulin, Basal insulin - Type 1 Diabetes Mellitus | Phase 2 | Recruiting | Mannkind Corporation | 100 | 2026-02-04 | 2026-08-13 |
| Twiist Postmarket Surveillance Study for Type 1 Diabetes twiist Automated Insulin Delivery System - Type 1 Diabetes (T1D), Type 1 Diabetes Mellitus | Recruiting | Deka Research and Development | 1875 | 2025-12-09 | 2026-01-21 | |
| Closed Loop and Education for Hypoglycemia Awareness Restoration Omnipod 5 or Medtronic 780G, My HypoCOMPaSS Education, HARPdoc Education - Diabetes Mellitus, Type 1 | Not applicable | Recruiting | Milton S. Hershey Medical Center | 324 | 2025-10-03 | 2026-03-03 |
| Studying the Presence of CFRD Complications With Thoughtful Recruitment (SPeCTRuM) observational study - Cystic Fibrosis (CF), Cystic Fibrosis-related Diabetes | Recruiting | Jaeb Center for Health Research | 200 | 2025-09-18 | 2026-02-10 | |
| Bifocal Spectacles vs. Single Vision Spectacles for Esotropia Greater at Near Bifocal Spectacles, Single Vision Lenses - Esotropia | Phase 3 | Withdrawn | Jaeb Center for Health Research | 2025-09-01 | 2025-05-31 | |
| Faricimab + PRP vs. Vitrectomy + Endolaser for Treatment of PDR Vitrectomy, Endolaser, Faricimab - Proliferative Diabetic Retinopathy (PDR) | Phase 3 | Recruiting | Jaeb Center for Health Research | 426 | 2025-08-04 | 2026-09-18 |
| Effect of Inhaled Technosphere Insulin vs RAA Insulin on Exercise-Induced Hypoglycemia in Adults With T1D Using Automated Insulin Delivery Control IQ + sleep or exercise activity with TI - Diabetes Mellitus, Type 1 | Not applicable | Recruiting | Jaeb Center for Health Research | 30 | 2025-06-05 | 2026-07-16 |
| Inhaled Insulin vs Rapid-acting Injections for Post-meal Glucose Control in Women With Gestational Diabetes Inhaled Technosphere Insulin - Diabetes, Gestational, Pregnancy Complications | Phase 2 / Phase 3 | Completed | Jaeb Center for Health Research | 30 | 2025-06-02 | 2026-10-19 |
| CGM for the Early Detection and Management of Hyperglycemia in Pregnancy Diabetes Treatment, Usual Care Group - Gestational Diabetes Mellitus in Pregnancy | Not applicable | Recruiting | Jaeb Center for Health Research | 6000 | 2025-05-27 | 2025-12-23 |
| T1D Pregnancy & Me Hybrid closed loop insulin delivery system - Diabetes Mellitus, Type 1, Pregnancy in Diabetics | Active not recruiting | Jaeb Center for Health Research | 500 | 2025-04-25 | 2026-08-19 |
Showing 20 of 177. Sign in to see all of them.
Diabetes Mellitus, Type 1 (63) · Amblyopia (24) · Diabetes Mellitus (20) · Diabetes Mellitus, Type 2 (13) · Hypoglycemia (11) · Diabetic Retinopathy (9) · Glucose Metabolism Disorders (4) · Insulin Resistance (4) · Motor Activity (4) · Refractive Errors (4) · Strabismus (4) · Autoimmune Diseases (3) · Edema (3) · Endocrine System Diseases (3) · Hyperglycemia (3)
Atropine (9) · Continuous Glucose Monitoring (7) · Eyeglasses (6) · Bevacizumab (5) · Lasers (5) · Ranibizumab (5) · Triamcinolone Acetonide (4) · aflibercept (4) · Adrenal Cortex Hormones (3) · Insulin (3) · salicylhydroxamic acid (3) · Botulinum Toxins, Type A (2) · Control Groups (2) · Glucagon (2) · Insulin Aspart (2)
United States (164) · Canada (21) · United Kingdom (14) · France (10) · Germany (7) · Israel (7) · Italy (6) · Netherlands (5) · Australia (3) · Austria (3) · Finland (3) · Switzerland (3) · Brazil (2) · Luxembourg (2) · Belgium (1)
John Lum, MS (8) · Roy W Beck, MD, PhD (7) · Bruce Buckingham, MD (5) · David K. Wallace, M.D. (5) · Roy Beck, MD, PhD (5) · David K Wallace, MD, MPH (4) · Fiona Campbell, MD (4) · Michael X. Repka, M.D. (4) · Nelly Mauras, MD (4) · Roman Hovorka, PhD (4) · William V Tamborlane, M.D. (4) · Bruce A Buckingham, MD (3) · Jordan Pinsker, MD (3) · William V. Tamborlane, MD (3) · Ajay Thankamony, MD (2)
PMID 20451898, PMID 22108357, PMID 42459945, PMID 21571677, PMID 36774994, PMID 37067353, PMID 17765429, PMID 20008710, PMID 20427088, PMID 22999634, PMID 25439614, PMID 26802783, PMID 34516656, PMID 15522375, PMID 16241867, PMID 16373890, PMID 16751032, PMID 16751033, PMID 16800753, PMID 17003293, PMID 17123615, PMID 17192334, PMID 17192346, PMID 17420366, PMID 17425442, PMID 17544778, PMID 17659061, PMID 17698196, PMID 17707330, PMID 17889075, PMID 18185135, PMID 18221427, PMID 18316700, PMID 18662829, PMID 18698292, PMID 18779236, PMID 18789533, PMID 19064841, PMID 19139333, PMID 19174719, PMID 19204228, PMID 19214130, PMID 19273785, PMID 19373126, PMID 19429875, PMID 19433712, PMID 19541265, PMID 19675193, PMID 19675206, PMID 19837791
U10EY011751 (37), U10EY014231 (14), U10EY018817 (11), U10EY014229 (9), UG1EY014231 (7), UC4DK108483 (5), 2UG1EY011751 (4), R01DK085591 (4), UG1EY011751 (3), M01RR000069 (2), U01DK127551 (2), 1UC4DK108520-01 (1), 1UC4DK108612-01 (1), 1UG1EY030030-01A1 (1), 1UG1EY030039-01A1 (1)