6 completed, 6 unknown, 3 recruiting, 1 active not recruiting. 7 Not applicable, 3 Phase 2, 3 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 7 | Unknown 3, Completed 2, Recruiting 1, Terminated 1 |
| Phase 2 | 3 | Unknown 2, Completed 1 |
| Phase 3 | 3 | Completed 1, Recruiting 1, Unknown 1 |
Follow Diplopia: new trials by email Literature Review of Diplopia trials Research Report on Diplopia
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Validation of AI-Based Quantitative Eye Movement Analysis From Smartphone 9-Gaze Videos (Glandy EOM) Glandy EOM (AI-based quantitative eye movement analysis software) - Ocular Motility Disorders, Strabismus | Not yet recruiting | THYROSCOPE INC. | 1000 | 2026-07-01 | 2026-06-03 | |
| A Randomized, Parallel-arm, Double Blind, Placebo-controlled Study to Assess the Efficacy of Fampridine for Patients With Spinocerebellar Ataxia SCA27B Caused by a GAA Expansion in the FGF14 Gene Fampridine 10 mg prolonged-release tablet (per os), Placebo (tablets per os) - Spinocerebellar Ataxia 27B (SCA27B) | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 70 | 2025-10-21 | 2025-12-10 |
| VisionApp - Ghosting Proclear 1 Day Contact Lens, MyDay Contact Lens, NaturalVue Contact Lens - Diplopia, Monocular | Not applicable | Recruiting | Indiana University | 12 | 2025-10-10 | 2026-08-24 |
| Understanding Visual Confusion Using Stereoscopic Displays Binocular visual confusion (unilateral opaque), Unilateral monocular visual confusion (unilateral see-through), Bilateral monocular visual confusion (bilateral see-through) - Diplopia, Binocular Vision Suppression | Not applicable | Completed | Massachusetts Eye and Ear Infirmary | 13 | 2021-11-09 | 2023-07-10 |
| Orbital Fractures Registry Primary "early" reconstruction, Nonsurgical, Primary "delayed" reconstruction - Orbital Fractures, Blow Out Fracture of Orbit | Active not recruiting | AO Innovation Translation Center | 300 | 2019-11-01 | 2026-05-26 | |
| Impact of a Magnetic Resonance Imaging (MRI) Scanner Exclusively Dedicated to Emergency in the Clinical Management of Patients Presenting With Diplopia or Dizziness Stroke, Dizziness | Completed | University Hospital, Strasbourg, France | 119 | 2018-07-24 | 2023-07-14 | |
| A Retrospective Study of the Effects of Ocular Acupuncture on Ocular Motor Nerve Palsy Ocular acupuncture - Oculomotor Nerve Palsy, Trochlear Nerve Palsy | Unknown | First Affiliated Hospital of Harbin Medical University | 900 | 2018-03-15 | 2018-03-12 | |
| Mobile Medical Application for Cost-effective Strabismus Screening Strabismus | Completed | Massachusetts Eye and Ear Infirmary | 91 | 2018-02-01 | 2025-07-14 | |
| Effects of Ocular Electroacupuncture on Oculomotor Nerve Palsy ocular electroacupuncture, ocular acupuncture, sham acupuncture - Oculomotor Nerve Palsy | Not applicable | Unknown | First Affiliated Hospital of Harbin Medical University | 177 | 2017-04-06 | 2017-04-04 |
| Effects of Ocular Electroacupuncture on Trochlear Nerve Palsy ocular electroacupuncture, ocular acupuncture, sham acupuncture - Trochlear Nerve Palsy | Not applicable | Unknown | First Affiliated Hospital of Harbin Medical University | 144 | 2017-04-06 | 2017-04-04 |
| Effects of Ocular Electroacupuncture on Abducens Nerve Palsy ocular electroacupuncture, ocular acupuncture, sham acupuncture - Abducens Nerve Paralysis | Not applicable | Unknown | First Affiliated Hospital of Harbin Medical University | 150 | 2017-04-06 | 2017-04-04 |
| A Predictive Score for the Ischemic Etiology of a Transient Diplopia (VASCO-DIP) Clinical, ophthalmological and neurological evaluation - Diplopia | Recruiting | Fondation Ophtalmologique Adolphe de Rothschild | 220 | 2015-09-24 | 2026-09-09 | |
| Analysis Between the Results of Two Surgical Techniques of Orbital Decompression in Patients With Graves Orbitopathy Orbital decompression - Graves Ophthalmopathy | Not applicable | Completed | University of Sao Paulo General Hospital | 42 | 2015-02-05 | 2019-08-13 |
| Bupivacaine Injection of Eye Muscles to Treat Strabismus Bupivacaine - Strabismus, Esotropia | Phase 2 / Phase 3 | Unknown | Smith-Kettlewell Eye Research Institute | 120 | 2012-04-01 | 2019-09-23 |
| Polycaprolactone / Tricalcium Phosphate (PCL/TCP) v Titanium Orbital Implant : Randomised Trial Polycaprolactone / Tri-Calcium Phosphate, Titanium Mesh - Fractures, Enophthalmos | Phase 2 | Unknown | National University Hospital, Singapore | 80 | 2010-04-01 | 2014-04-28 |
| Idiopathic Intracranial Hypertension Treatment Trial Acetazolamide, Placebo, Formal weight loss counselling program - Idiopathic Intracranial Hypertension | Phase 2 / Phase 3 | Completed | St. Luke's-Roosevelt Hospital Center | 165 | 2010-01-01 | 2018-12-12 |
| Effects of Prismatic Spectacle Lenses on Symptoms of Dizziness, Headache and Anxiety as Caused by Vertical Heterophoria Lenses containing prismatic correction, Lenses not containing prismatic correction - Binocular Dysfunction, Vertical Heterophoria | Not applicable | Terminated | Vision Specialists of Birmingham | 13 | 2008-11-01 | 2020-10-12 |
| Effect of Brimonidine Tartrate Ophthalmic Solution 0.15% on Pupil Diameter in Normal Eyes Brimonidine tartrate ophthalmic solution 0.15% (Alphagan P) - Healthy | Completed | Walter Reed Army Medical Center | 20 | 2006-12-20 |
Ocular Motility Disorders (4) · Strabismus (3) · Abducens Nerve Diseases (2) · Dizziness (2) · Graves Disease (2) · Graves Ophthalmopathy (2) · Headache (2) · Oculomotor Nerve Diseases (2) · Trochlear Nerve Diseases (2) · Agoraphobia (1) · Amblyopia (1) · Anxiety Disorders (1) · Asthenopia (1) · Ataxia (1)
Eye Diseases (18) · Nervous System Diseases (18) · Neurologic Manifestations (18) · Pathological Conditions, Signs and Symptoms (18) · Sensation Disorders (18) · Signs and Symptoms (18) · Vision Disorders (17) · Cranial Nerve Diseases (8) · Central Nervous System Diseases (7) · Orbital Diseases (4) · Autoimmune Diseases (3) · Brain Diseases (3) · Endocrine System Diseases (3) · Goiter (3) · Hyperthyroidism (3)
4-Aminopyridine (1) · Acetaminophen (1) · Acetazolamide (1) · Aspirin (1) · Brimonidine Tartrate (1) · Bupivacaine (1) · Codeine (1) · Conservative Treatment (1) · Contact Lenses (1) · Ibuprofen (1) · Naproxen (1) · Periodontal Debridement (1) · Surgical Procedures, Operative (1) · butalbital (1)
First Affiliated Hospital of Harbin Medical University (4) · Massachusetts Eye and Ear Infirmary (2) · AO Innovation Translation Center (1) · Assistance Publique - Hôpitaux de Paris (1) · Fondation Ophtalmologique Adolphe de Rothschild (1) · Indiana University (1) · National University Hospital, Singapore (1) · Smith-Kettlewell Eye Research Institute (1) · St. Luke's-Roosevelt Hospital Center (1) · THYROSCOPE INC. (1) · University Hospital, Strasbourg, France (1) · University of Sao Paulo General Hospital (1) · Vision Specialists of Birmingham (1) · Walter Reed Army Medical Center (1)
United States (9) · China (3) · France (3) · Brazil (1) · Canada (1) · Germany (1) · Netherlands (1) · Pakistan (1) · Qatar (1) · Romania (1) · Russia (1) · Serbia (1) · Singapore (1) · South Africa (1) · Spain (1)
Lingyun Zhou, PhD (3) · Alan B Scott, MD (1) · Eppo B. Wolvius, Prof. (1) · Gang Luo, PhD (1) · JaeHyun Jung (1) · Joel M Miller, PhD (1) · Mark S Rosner, MD (1) · Michael Wall, MD (1) · Thiam Chye Lim, MD (1)
PMID 15824215, PMID 17502505, PMID 20126486, PMID 21683635, PMID 24756302, PMID 24756514, PMID 24781936, PMID 25370510, PMID 25370513, PMID 26024112, PMID 26335066, PMID 26618282, PMID 26778344, PMID 26934136, PMID 27694262, PMID 28130349, PMID 28492874, PMID 32832143, PMID 33852655, PMID 35554653, PMID 40738644
R01EY031777 (1), R44EY025902 (1), U10EY017281 (1), U10EY017387 (1)