7 completed, 2 terminated, 1 unknown. 10 Phase 3, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 10 | Completed 7, Terminated 2, Unknown 1 |
| Phase 2 | 1 | Completed 1 |
Follow Hydrocephalus: new trials by email Literature Review of Hydrocephalus trials Research Report on Hydrocephalus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Isoflurane-induced Neuroinflammation in Children With Hydrocephalus Isoflurane, Dexmedetomidine - Toxicity, Hydrocephalus | Phase 3 | Terminated | Nationwide Children's Hospital | 25 | 2015-07-01 | 2018-12-13 |
| The CSF Shunt Entry Site Trial Ventriculoperitoneal shunt insertion surgery - Hydrocephalus | Phase 3 | Unknown | Baylor College of Medicine | 448 | 2015-04-01 | 2020-11-12 |
| Intraoral 30% Glucose Effect In Newborns 30% Glucose, Midazolam - Epilepsy, Hydrocephaly | Phase 3 | Completed | Baskent University | 19 | 2014-01-01 | 2014-12-30 |
| Randomized Controlled Trial of Shunt vs ETV/CPC for PIH in Ugandan Infants Chhabra Shunt Placement, ETV/CPC - Hydrocephalus | Phase 3 | Completed | Boston Children's Hospital | 100 | 2013-05-27 | 2026-11-12 |
| A Randomised Controlled Trial of Lumbar Drainage to Treat Communicating Hydrocephalus After Severe Intraventricular Hemorrhage Lumbar drainage - Intracerebral Hemorrhage, Obstructive Hydrocephalus | Phase 2 / Phase 3 | Completed | University of Erlangen-Nürnberg Medical School | 30 | 2012-05-01 | 2016-10-27 |
| Positron Emission Tomography Imaging of Brain Amyloid in Normal Pressure Hydrocephalus [18F]Flutemetamol - Normal Pressure Hydrocephalus | Phase 3 | Terminated | GE Healthcare | 12 | 2010-03-01 | 2013-12-13 |
| PET Imaging of Brain Amyloid in Normal Pressure Hydrocephalus [18F] Flutemetamol - Normal Pressure Hydrocephalus | Phase 3 | Completed | GE Healthcare | 7 | 2009-12-01 | 2012-06-11 |
| A Precision and Accuracy Study of the Codman Valve Position Verification (VPV) System. Codman VPV System - Hydrocephalus, Normal Pressure Hydrocephalus | Phase 3 | Completed | Codman & Shurtleff | 274 | 2004-09-01 | 2012-05-28 |
| Impact of Ventricular Catheter Used With Antimicrobial Agents on Patients With a Ventricular Catheter Antibiotics-impregnated ventricular catheter (Bactiseal®), Plain ventricular catheter (Codman EDS II/III) - Hydrocephalus, Intracranial Hypertension | Phase 3 | Completed | Chinese University of Hong Kong | 184 | 2004-04-01 | 2009-12-23 |
| Premature Infants in Need of Transfusion (PINT) Red blood cell transfusion - Anemia of Prematurity | Phase 3 | Completed | McMaster University | 424 | 2001-02-01 | 2015-09-24 |
Hydrocephalus, Normal Pressure (3) · Alzheimer Disease (2) · Anemia (1) · Bronchopulmonary Dysplasia (1) · Cerebral Hemorrhage (1) · Epilepsy (1) · Intracranial Hypertension (1) · Leukomalacia, Periventricular (1) · Retinopathy of Prematurity (1)
Brain Diseases (10) · Central Nervous System Diseases (10) · Nervous System Diseases (10) · Cardiovascular Diseases (2) · Cerebrovascular Disorders (2) · Dementia (2) · Mental Disorders (2) · Neurocognitive Disorders (2) · Neurodegenerative Diseases (2) · Tauopathies (2) · Vascular Diseases (2) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (1) · Encephalomalacia (1) · Eye Diseases (1)
flutemetamol (2) · Dexmedetomidine (1) · Erythrocyte Transfusion (1) · Glucose (1) · Isoflurane (1) · Midazolam (1)
GE Healthcare (2) · Baskent University (1) · Baylor College of Medicine (1) · Boston Children's Hospital (1) · Chinese University of Hong Kong (1) · Codman & Shurtleff (1) · McMaster University (1) · Nationwide Children's Hospital (1) · University of Erlangen-Nürnberg Medical School (1)
United States (5) · Canada (2) · Australia (1) · China (1) · Germany (1) · Uganda (1)
Kim A Mansfield, MS (2) · Benjamin C Warf, MD (1) · Chad Andersen, MD (1) · Dimitre Staykov, MD (1) · Elizabeth Asztalos, MD, MSc (1) · George KC Wong, FRCSEd(SN) (1) · Hagen Huttner, MD (1) · Haresh Kirpalani, MD, MSc (1) · J. Thomas Megerian, MD (1) · John Kestle, MD (1) · Joseph Tobias, M.D. (1) · Morris Blajchman, PhD (1) · Nancy Heddle, MSc (1) · Robin K Whyte, MD (1)
PMID 16939737, PMID 19117884, PMID 20466698, PMID 27888608, PMID 29262276, PMID 31086941, PMID 34911199, PMID 40489263, PMID 42757834
R01HD085853 (1)