11 completed, 4 terminated, 2 recruiting, 1 active not recruiting. 8 Phase 3, 6 Phase 2, 2 Phase 1, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 8 | Completed 6, Terminated 2 |
| Phase 2 | 6 | Completed 3, Not yet recruiting 1, Recruiting 1, Terminated 1 |
| Phase 1 | 2 | Active not recruiting 1, Completed 1 |
| Early Phase 1 | 1 | Terminated 1 |
Follow flutemetamol: new trials by email Literature Review of flutemetamol trials Research Report on flutemetamol
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Flutemetamol F 18 Injection Formulation Comparison GE-287, Vizamyl - Cognitive Dysfunction | Phase 2 | Not yet recruiting | GE Healthcare | 20 | 2026-09-22 | 2026-10-14 |
| Ultralow Dose PET Imaging of 18F-Florbetapir, 18F-Flutemetamol 18F-Florbetapir or 18F-Flutemetamol - Alzheimer Disease, Mild Cognitive Impairment | Phase 2 | Recruiting | Akiva Mintz | 200 | 2025-05-20 | 2026-04-13 |
| Parametric Cardiac 18F-flutemetamol PET Imaging in ATTR Cardiomyopathy (18F)Flutemetamol - Cardiomyopathies, Primary | Phase 1 | Completed | Yale University | 12 | 2022-08-16 | 2025-08-03 |
| Head-to-Head Harmonization of Tau Tracers in Alzheimer's Disease 18F-Flortaucipir radiopharmaceutical, 18F-MK-6240 radiopharmaceutical, Amyloid-β radiopharmaceutical (11C-PiB or 18F-Florbetaben or 18F-NAV-4694 or 18F-Flutemetamol) - Alzheimer Disease | Phase 1 | Active not recruiting | Tharick Pascoal | 822 | 2022-03-02 | 2026-09-08 |
| Amyloid Plaque Deposition in Chemotherapy-Induced Cognitive Impairment [18F]Flutemetamol, [18F]fluoro-2-deoxy-D-glucose (FDG), Functional Magnetic Resonance Imaging (fMRI) - Breast Cancer | Phase 2 | Terminated | University of Utah | 15 | 2018-01-31 | 2024-11-20 |
| Assessment of Cardiac Fixation During PET Using a New Drug Within Amyloid Cardiac Injuries. PET with 18 F-Flutemetamol - Cardiac Amyloidosis | Early Phase 1 | Terminated | University Hospital, Toulouse | 7 | 2017-03-15 | 2020-08-26 |
| Brain Characterization of Amyloid Protein and Glucose Metabolism of ALFA Project Participants 18F-Flutemetamol & 18F-FDG - Alzheimer's Disease | Recruiting | Barcelonabeta Brain Research Center, Pasqual Maragall Foundation | 570 | 2017-03-01 | 2025-05-31 | |
| Implications for Management of PET Amyloid Classification Technology [18F]Flutemetamol - Mild Cognitive Impairment, Dementia | Completed | University of Utah | 41 | 2016-06-01 | 2023-04-24 | |
| Investigating the Clinical Consequences of Flutemetamol-PET-scanning Flutemetamol (Vizamyl) - Mild Cognitive Impairment, Alzheimer's Disease | Phase 3 | Terminated | University of Zurich | 11 | 2015-05-01 | 2020-01-21 |
| Longitudinal Study of Brain Amyloid imaGing in MEMENTO Flutemetamol (18F), Florbetapir (18F) - Alzheimer's Disease (AD) and Related Disorders | Phase 3 | Completed | University Hospital, Bordeaux | 448 | 2014-06-10 | 2022-02-03 |
| Comparison of PET Amyloid Imaging in Japanese and Western Subjects [18F] Flutemetamol - Mild Cognitive Impairment, Alzheimer's Disease | Phase 2 | Completed | GE Healthcare | 70 | 2012-10-01 | 2017-06-05 |
| Bridging Study of C11 Pittsburgh Compound B (PiB) and F18 Flutemetamol Brain Positron Emission Tomography (PET) C11 PiB, F18 Flutametamol - Alzheimer's Disease | Phase 2 | Completed | Mayo Clinic | 89 | 2012-07-01 | 2017-04-18 |
| Effectiveness of an Electronic Training Program for Orienting and Interpreting [18F]Flutemetamol Positron Emission Tomography (PET) Images [18F]Flutemetamol - Alzheimer's Disease, Mild Cognitive Impairment | Phase 3 | Completed | GE Healthcare | 276 | 2012-07-01 | 2014-01-24 |
| Practice Effects and Amyloid Imaging Using 18F-PIB or Flutemetamol PET and FDG-PET 18F-Flutemetamol - Alzheimer's Disease | Phase 2 | Completed | University of Utah | 27 | 2011-05-01 | 2023-05-09 |
| Positron Emission Tomography (PET) Amyloid Imaging of the Brain in Healthy Young Adult Subjects [18F] Flutemetamol - Healthy | Phase 3 | Completed | GE Healthcare | 218 | 2010-12-01 | 2013-07-02 |
| Positron Emission Tomography (PET) Imaging of Brain Amyloid Compared to Post-Mortem Levels [18F] Flutemetamol - Brain Fibrillarab Levels | Phase 3 | Completed | GE Healthcare | 203 | 2010-05-01 | 2013-12-04 |
| Positron Emission Tomography Imaging of Brain Amyloid in Normal Pressure Hydrocephalus [18F]Flutemetamol - Normal Pressure Hydrocephalus | Phase 3 | Terminated | GE Healthcare | 12 | 2010-03-01 | 2013-12-13 |
| Assess the Prognostic Usefulness of Flutemetamol (18F) Injection for Identifying Subjects With Amnestic Mild Cognitive Impairment Who Will Convert to Clinically Probable Alzheimer's Disease Flutemetamol (18F) Injection - Mild Cognitive Impairment, Alzheimer's Disease | Phase 3 | Completed | GE Healthcare | 365 | 2009-12-01 | 2014-09-11 |
| PET Imaging of Brain Amyloid in Normal Pressure Hydrocephalus [18F] Flutemetamol - Normal Pressure Hydrocephalus | Phase 3 | Completed | GE Healthcare | 7 | 2009-12-01 | 2012-06-11 |
Alzheimer Disease (16) · Cognitive Dysfunction (9) · Dementia (3) · Hydrocephalus, Normal Pressure (2) · Amyloid Neuropathies, Familial (1) · Amyloidosis, Hereditary, Transthyretin-Related (1) · Breast Neoplasms (1) · Cardiomyopathies (1) · Communication Disorders (1) · Stroke (1) · Tauopathies (1)
GE Healthcare (8) · University of Utah (3) · Akiva Mintz (1) · Barcelonabeta Brain Research Center, Pasqual Maragall Foundation (1) · Mayo Clinic (1) · Tharick Pascoal (1) · University Hospital, Bordeaux (1) · University Hospital, Toulouse (1) · University of Zurich (1) · Yale University (1)
United States (13) · France (2) · Spain (2) · Canada (1) · Switzerland (1)
Kim A Mansfield, MS (2) · Paul Sherwin, MD, PhD (2) · Christoph Hock, MD, Prof. (1) · Edward J Miller, MD (1) · John M. Hoffman, M.D. (1) · Jose Luis Molinuevo, MD, PhD (1) · Kevin Duff, Ph.D. (1) · Levent Ture (1) · Norman L. Foster, M.D. (1)
PMID 11488533, PMID 16631014, PMID 18382889, PMID 2394453, PMID 25551524, PMID 26209803, PMID 26224076, PMID 27652282, PMID 27955679, PMID 28181118, PMID 29019612, PMID 29048471, PMID 29305186, PMID 30095083, PMID 30123935, PMID 30145929, PMID 30343093, PMID 30902090, PMID 30915522, PMID 30938420, PMID 31140154, PMID 31400950, PMID 31480867, PMID 31727169, PMID 32078382, PMID 32400202, PMID 32430600, PMID 32936265, PMID 33025472, PMID 33597012, PMID 35351181, PMID 36856866, PMID 37777806, PMID 38048354, PMID 38412412, PMID 42208563, PMID 8176464, PMID 8784228
R01AG073267 (1)