3 completed, 3 unknown, 1 not yet recruiting, 1 withdrawn. 8 Phase 2, 3 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 8 | Completed 3, Unknown 3, Not yet recruiting 1, Withdrawn 1 |
| Phase 1 | 3 | Not yet recruiting 1, Unknown 1, Withdrawn 1 |
| Phase 3 | 1 | Completed 1 |
Follow Hydrocephalus: new trials by email Literature Review of Hydrocephalus trials Research Report on Hydrocephalus
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Ventricular mTOR Inhibition to Prevent Hydrocephalus After Brain Hemorrhage Sirolimus (Rapamune®) - Post-hemorrhagic Hydrocephalus (PHH) | Phase 1 / Phase 2 | Not yet recruiting | Massachusetts General Hospital | 15 | 2027-01-01 | 2026-06-25 |
| The Safety and Efficacy of Rapamycin on Communicating Hydrocephalus Secondary to Intraventricular Hemorrhage Rapamycin - Communicating Hydrocephalus, Cerebral Intraventricular Hemorrhage | Phase 2 | Unknown | Beijing Tiantan Hospital | 53 | 2024-08-01 | 2024-08-21 |
| Acetazolamide Trial in Normal Pressure Hydrocephalus Acetazolamide, Placebo - Idiopathic Normal Pressure Hydrocephalus (INPH) | Phase 2 | Completed | Uppsala University Hospital | 50 | 2022-02-17 | 2026-05-06 |
| Improvement of Peritoneal Catheter Placement in VPS With a Splitable Trocar Open Mini-Laparotomy, Abdominal Puncture - Hydrocephalus | Phase 1 / Phase 2 | Unknown | Southern Medical University, China | 40 | 2022-01-01 | 2022-08-01 |
| Acetazolamide for Treating NPH in Shunt-candidates Patients Acetazolamide - Normal Pressure Hydrocephalus | Phase 2 | Unknown | Rabin Medical Center | 15 | 2018-12-01 | 2018-12-19 |
| Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage Tissue Plasminogen Activator - Subarachnoid Hemorrhage, Cerebral Vasospasm | Phase 1 / Phase 2 | Withdrawn | Rush University Medical Center | 2015-03-01 | 2015-11-11 | |
| A Randomised Controlled Trial of Lumbar Drainage to Treat Communicating Hydrocephalus After Severe Intraventricular Hemorrhage Lumbar drainage - Intracerebral Hemorrhage, Obstructive Hydrocephalus | Phase 2 / Phase 3 | Completed | University of Erlangen-Nürnberg Medical School | 30 | 2012-05-01 | 2016-10-27 |
| A Study Comparing Two Treatments for Infants With Hydrocephalus Endoscopic Third Ventriculostomy, CSF Shunt Insertion - Hydrocephalus | Phase 2 | Completed | The Hospital for Sick Children | 182 | 2005-09-01 | 2018-09-10 |
Hydrocephalus, Normal Pressure (2) · Cerebral Hemorrhage (1) · Cerebral Intraventricular Hemorrhage (1) · Intracranial Aneurysm (1) · Intracranial Hemorrhages (1) · Subarachnoid Hemorrhage (1) · Vasospasm, Intracranial (1)
Brain Diseases (8) · Central Nervous System Diseases (8) · Nervous System Diseases (8) · Cardiovascular Diseases (4) · Cerebrovascular Disorders (4) · Hemorrhage (4) · Pathologic Processes (4) · Pathological Conditions, Signs and Symptoms (4) · Vascular Diseases (4) · Intracranial Hemorrhages (3) · Aneurysm (1) · Cerebral Hemorrhage (1) · Intracranial Arterial Diseases (1)
Acetazolamide (2) · Sirolimus (2) · Tissue Plasminogen Activator (1) · Ventriculostomy (1)
Beijing Tiantan Hospital (1) · Massachusetts General Hospital (1) · Rabin Medical Center (1) · Rush University Medical Center (1) · Southern Medical University, China (1) · The Hospital for Sick Children (1) · University of Erlangen-Nürnberg Medical School (1) · Uppsala University Hospital (1)
United States (3) · China (2) · Germany (2) · Israel (2) · Argentina (1) · Brazil (1) · Canada (1) · Hungary (1) · India (1) · Italy (1) · Netherlands (1) · Poland (1) · Russia (1) · Serbia (1) · Spain (1)
Abhaya Kulkarni, MD (1) · Dimitre Staykov, MD (1) · Guoyi Gao, MD (1) · Hagen Huttner, MD (1) · Johan Virhammar, MD, PhD (1) · Kristopher Kahle, MD, PhD (1) · Roham Moftakhar, MD (1) · Runfa Tian, MD (1) · Shlomi Constantini, MD (1) · Spyros Sgouros, MD (1) · Stephan Munich, MD (1) · Yosi Laviv, MD (1) · Zhen-Zhou Chen, Dr. (1)
PMID 25534231, PMID 27107887, PMID 27888608, PMID 28357554, PMID 29363332, PMID 29987375, PMID 32028009, PMID 36803604, PMID 42127932