59 completed, 13 unknown, 3 not yet recruiting, 3 recruiting. 80 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 80 | Completed 59, Unknown 13, Not yet recruiting 3, Recruiting 3, Active not recruiting 2 |
Follow Gingival Diseases: new trials by email Literature Review of Gingival Diseases trials Research Report on Gingival Diseases
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Oral Hygiene Assistance Training Program Stannous Fluoride Toothpaste (SnF), sodium fluoride 5000 ppm, cetylpyridinium chloride (0.075%) and zinc alcohol free mouthwash - Elderly, Periodontal Disease | Phase 4 | Not yet recruiting | Colgate Palmolive | 500 | 2026-09-20 | 2026-09-08 |
| Investigation of the Interplay Between Local Oral Inflammation, Microbiota and Systemic Immune Responses. Stannous Fluoride Toothpaste (SnF) - Gingival Inflammation | Phase 4 | Not yet recruiting | Colgate Palmolive | 20 | 2026-09-01 | 2026-09-03 |
| Clinical Study to Collect and Analyze Dental Plaque and Oral Health Measures in a Population With High Plaque/Low Gingivitis and High Plaque/High Gingivitis sodium monofluorophosphate toothpaste - Gingivitis, Plaque | Phase 4 | Recruiting | Colgate Palmolive | 100 | 2026-04-20 | 2026-05-29 |
| Evaluation of the Anti-plaque Effect of a Bioflavonoid-based Antiseptic Mouthwash Bioflavonoid mouthwash, Chlorhexidine 0.12% mouthwash - Gingival Inflammation, Dental Plaque Accumulation | Phase 4 | Completed | University of Barcelona | 24 | 2026-03-02 | 2026-09-17 |
| Comparison Between the Effect of Triclosan Toothpaste and Chlorhexidine Mouthwash on Gingival Health in a Group of Fixed Orthodontic Patients: A Randomized Controlled Clinical Trial Triclosan 0.3% toothpaste, sodium fluoride 0.24% toothpaste, Chlorhexidine 0.2% mouthwash - Gingival Inflammation | Phase 4 | Completed | University of Science and Technology, Yemen | 60 | 2026-02-14 | 2026-09-11 |
| 6-month Clinical Investigation Assessing the Efficacy of an Antimicrobial Mouthrinse in Reducing Established Plaque and Improving Gum Health Test Mouthrinse, Control Mouthrinse - Gingivitis, Dental Plaque Accumulation | Phase 4 | Recruiting | Colgate Palmolive | 90 | 2026-01-28 | 2026-02-17 |
| Assessing Gingivitis and Plaque From a Marketed Toothpaste Stannous Fluoride Dentifrice, Test Stannous Fluoride Dentifrice, Sodium monofluorophosphate dentifrice - Gingivitis | Phase 4 | Active not recruiting | Procter and Gamble | 120 | 2025-08-30 | 2025-09-23 |
| Comparative Efficacy of Floss and Essential Oil/CPC+Zn Mouthwashes in Reducing Dental Plaque and Gingivitis Mouthwash, Floss, Toothbrush - Dental Plaque, Gingivitis | Phase 4 | Completed | Colgate Palmolive | 228 | 2025-07-07 | 2025-10-30 |
| Coronally Advanced Tunnel Combined With Xenogenic Dermal Matrix and L-PRF Coronally Advanced Tunel + ADM (Novomatrix®), Coronally Advanced Tunel + ADM (Novomatrix®) + L-PRF - Gingival Recession, Gingival Recession, Localized | Phase 4 | Not yet recruiting | Andres Matteo Pascual La Rocca | 44 | 2025-04-01 | 2025-01-28 |
| Clinical and Microbiological Evaluation Of The Efficacy Of Herbal Mouthwashes in Gingivitis Tea tree oil, Thyme oil hydrosol, LISTERINE ZERO Alcohol Mouthwash COOL MINT - Periodontal Diseases | Phase 4 | Completed | Altinbas University | 52 | 2025-02-28 | 2026-08-13 |
| Microderm for Root Coverage Procedures Alloderm, MicroDerm - Connective Tissue Graft, Gum Recession | Phase 4 | Active not recruiting | Ohio State University | 20 | 2025-02-13 | 2025-11-26 |
| Comparison of Effectiveness of Gingival Displacement Using Retraction Cord and Aluminum Chloride Gel knitted cotton retraction cord, aluminum chloride gel - Gingival Bleeding, Prosthesis Failure, Dental | Phase 4 | Recruiting | Dow University of Health Sciences | 66 | 2024-09-11 | 2025-12-01 |
| The Efficacy of Amnion Chorion Allograft in Management of Gingival Recession. Amnion Chorion membrane, connective tissue graft - Gingival Recession, Localized | Phase 4 | Completed | Minia University | 28 | 2024-08-01 | 2025-05-29 |
| Reconstruction of Deficient Interdental Papilla Using Stem Cells vs Physiological Saline Umbilical cord-mesenchymal stem cells - Gingival Recession, Localized | Phase 4 | Unknown | University of Malaya | 20 | 2023-12-01 | 2024-05-01 |
| Salivary Drug Concentration Exploratory Study of Cetylpyridinium Chloride Buccal Tablets Cetylpyridinium Chloride Buccal Tablets - Pharyngitis Acute, Gingivitis | Phase 4 | Completed | Peking University People's Hospital | 10 | 2023-04-10 | 2023-07-12 |
| Protocol Efficacy of Mouthwashes in Experimental Gingivitis StellaLife, Chlorhexidine - Gingivitis | Phase 4 | Completed | Stony Brook University | 34 | 2023-01-11 | 2025-12-08 |
| Toothpastes With Thermal Water for Oral Health BUCCOTHERM® Sensitive Gums with Fluoride, BUCCOTHERM® Sensitive Gums Fluoride-Free - Gingivitis, Dentin Hypersensitivity | Phase 4 | Completed | I.M. Sechenov First Moscow State Medical University | 84 | 2022-11-01 | 2023-03-01 |
| Root Coverage Using ADM and Coronally Positioned Tunnel With or Without Enamel Matrix Derivative Regenerative tissue matrix and enamel matrix derivative, Regenerative tissue matrix - Recession, Gingival | Phase 4 | Completed | University of Louisville | 24 | 2022-10-06 | 2026-02-10 |
| The Effects of Fixed Space Maintainers Luting with Self-Adhesive Resin Cement on the Gingival Crevicular Fluid of Interleukin-18 Level Voco Meron Conventional Glass Ionomer, High-Q-Bond Band™ self-adhesive resin cement. - Gingival and Periodontal Disease, Space Maintenance | Phase 4 | Completed | Afyonkarahisar Health Sciences University | 36 | 2022-06-13 | 2025-02-06 |
| A Study of Experimental Mouthwashes Colgate (R) Cavity Protection Toothpaste, Colgate (R) Cello Toothbrush, Prototype 1 Mouthwash - Gingivitis, Plaque | Phase 4 | Completed | Johnson & Johnson Consumer Inc. (J&JCI) | 274 | 2021-11-15 | 2023-11-13 |
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Gingivitis (48) · Gingival Recession (27) · Dental Plaque (8) · Periodontal Diseases (7) · Plaque, Amyloid (4) · Dental Caries (3) · Gingival Hemorrhage (3) · Periodontitis (3) · Pain (2) · Bacteremia (1) · Bone Diseases, Metabolic (1) · Dentin Sensitivity (1) · Diabetes Mellitus (1) · Inflammation (1)
Mouth Diseases (80) · Stomatognathic Diseases (80) · Periodontal Diseases (73) · Infections (48) · Periodontal Atrophy (27) · Pathological Conditions, Signs and Symptoms (12) · Tooth Diseases (12) · Dental Deposits (8) · Pathologic Processes (5) · Pathological Conditions, Anatomical (4) · Hemorrhage (3) · Oral Hemorrhage (3) · Signs and Symptoms (3) · Tooth Demineralization (3)
Chlorhexidine (6) · Alloderm (5) · Triclosan (5) · Cetylpyridinium (4) · Mouthwashes (4) · hydrated silica gel-based toothpaste (4) · Ethanol (3) · Oils, Volatile (3) · Sodium Fluoride (3) · chlorhexidine gluconate (3) · Acetaminophen (2) · Dental Devices, Home Care (2) · Listerine (2) · Tin Fluorides (2) · Toothpastes (2)
Colgate Palmolive (12) · Procter and Gamble (5) · Cairo University (3) · Krishnadevaraya College of Dental Sciences & Hospital (3) · University of Taubate (3) · GlaxoSmithKline (2) · Johnson & Johnson Consumer Inc. (J&JCI) (2) · Universidade Federal Fluminense (2) · University of Campinas, Brazil (2) · University of Louisville (2) · University of Oslo (2) · Università degli Studi di Sassari (2) · Afyonkarahisar Health Sciences University (1) · Aga Khan University (1) · Altinbas University (1)
United States (20) · Brazil (9) · Italy (5) · Egypt (4) · Germany (4) · India (4) · Canada (3) · Spain (3) · Turkey (Türkiye) (3) · United Kingdom (3) · Norway (2) · Pakistan (2) · Switzerland (2) · Belgium (1) · China (1)
Chhaju Ram Goyal, DDS (2) · Enilson A Sallum, PhD (2) · Ronaldo B Santana, DDS,MScD,DSc (2) · Aaron Biesbrock, DMD, PhD (1) · Abdullah AlAlwani, DDS (1) · Ahmed Khalil, professor (1) · Anton Sculean, Prof. Dr. med. dent. (1) · Armeen Fakhur, bds (1) · Aya Mohammed, Lecturer (1) · Bindu Dukka, BDS, MSD, MPH (1) · David Paquette, DMD (1) · Dr. Joann P George, MDS (1) · Dr.Dhanashree R. Agarwal, B.D.S. (1) · Elcio Marcantonio Jr, Professor (1)
PMID 19968743, PMID 11737510, PMID 12666710, PMID 14296927, PMID 14489483, PMID 14710766, PMID 15341352, PMID 15766375, PMID 16460251, PMID 18269662, PMID 18622483, PMID 19254123, PMID 19678861, PMID 20350159, PMID 20618550, PMID 20881341, PMID 21491012, PMID 21507033, PMID 23050490, PMID 23627374, PMID 23638764, PMID 23644602, PMID 24060558, PMID 25373688, PMID 25762359, PMID 25981528, PMID 26087570, PMID 26094684, PMID 26191050, PMID 27310522, PMID 275281, PMID 28753100, PMID 28821290, PMID 29216779, PMID 29948276, PMID 34511098, PMID 3540026, PMID 37885337, PMID 37985697, PMID 3866056, PMID 42481985, PMID 4269603, PMID 4269606, PMID 5237684, PMID 5264376, PMID 7012186, PMID 7593704, PMID 8583018, PMID 9350557
2015 (1)