121 completed, 85 unknown, 31 recruiting, 24 not yet recruiting. 196 Not applicable, 17 Phase 2, 11 Phase 4, 7 Phase 3, 6 Phase 1.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| HTO and Tranexamic Acid Study Tranexamic Acid, Routine medial opening wedge high tibial osteotomy - Osteoarthritis, Knee | Phase 3 | Not yet recruiting | Western University, Canada | 200 | 2027-01-01 | 2026-09-17 |
| Airway Dysfunction, Occlusions and Remodeling: COPD Patients and Mepolizumab Mepolizumab 100 MG Injection - COPD (Chronic Obstructive Pulmonary Disease) | Phase 4 | Not yet recruiting | Western University, Canada | 36 | 2026-10-01 | 2026-08-06 |
| REverse LuNg Airway and Vascular RemOdeling in Asthma ReMission (ReNORM) Biologic Therapy - Asthma; Eosinophilic | Not applicable | Not yet recruiting | Western University, Canada | 200 | 2026-10-01 | 2026-07-31 |
| Oral and Sublingual Ketamine 75 mg of oral ketamine, Sublingual ketamine 75 mg - Major Depression Severe | Phase 1 | Not yet recruiting | Western University, Canada | 10 | 2026-10-01 | 2026-07-06 |
| Exercise and Diabetes Interventions to Improve Brain Health in Older Adults With Type 2 Diabetes semaglutide, Moderate-Intensity Resistance Exercise, Balance and Tone (BAT) Exercise - Type 2 Diabetes, Cognitive Decline in Older Adults | Phase 4 | Not yet recruiting | Western University, Canada | 164 | 2026-09-01 | 2026-08-20 |
| Post-osteoporotic Fracture Exercise Program Exercise Program - Osteoporosis, Osteoporotic Fracture | Not applicable | Not yet recruiting | Western University, Canada | 100 | 2026-09-01 | 2026-08-20 |
| Labral Repair vs Reconstruction Labral Repair, Labral Reconstruction - Femoral Acetabular Impingement | Not applicable | Not yet recruiting | Western University, Canada | 220 | 2026-09-01 | 2026-08-31 |
| 3D Ultrasound in Hemophilic Ankles Mechanical Ultrasound - Hemophilia | Not applicable | Enrolling by invitation | The Hospital for Sick Children | 11 | 2026-08-25 | 2026-10-14 |
| Sensory Stimuli During Cesarean Delivery Patient-initiated request for pharmacological intervention during cesarean delivery - Intraoperative Pain | Recruiting | University of British Columbia | 1005 | 2026-07-20 | 2026-08-03 | |
| 129-Xe MRI Study of Single Triple Therapy Inhaler Effects in COPD Patients With Moderate-severe Dyspnea and/or Poor Health Status With High or Low Risk of Exacerbation fluticasone furoate(FF)/umeclidinium (UMEC)/vilanterol(VI) (100/62.5/25) mcg - Chronic Obstructive Pulmonary Disease (COPD) | Phase 4 | Recruiting | Western University, Canada | 60 | 2026-04-24 | 2026-07-31 |
| Piloting a Brief, Online Intervention for Suicidality in Sexual and Gender Minority Youth KindMind - Suicidal Thoughts, Sexual and Gender Minorities | Not applicable | Recruiting | Western University | 250 | 2026-02-01 | 2026-08-21 |
| Feasibility and Usability of a Mobile App for Monitoring and Managing Functional Movement Disorders Functional Movement Disorder | Not yet recruiting | Western University, Canada | 10 | 2026-02-01 | 2026-01-28 | |
| Action Outcome Latencies as a Measure of Sense of Agency in Functional Movement Disorders. Functional Movement Disorder | Not yet recruiting | Western University, Canada | 30 | 2026-01-31 | 2026-01-21 | |
| A Study Looking at a New Nerve Surgery to Help Men Regain Erections After Prostate Cancer Surgery Post radical prostatectomy nerve restoration procedure (PRP-NR) - Prostate Cancer, Erectile Dysfunction Following Radical Prostatectomy | Not applicable | Recruiting | Sir Mortimer B. Davis - Jewish General Hospital | 100 | 2026-01-30 | 2026-03-10 |
| POCUS-Guided Esmolol in Septic Shock: A Pilot RCT Esmolol - Septic Shock | Phase 1 / Phase 2 | Not yet recruiting | John Basmaji | 100 | 2026-01-15 | 2026-01-06 |
| The Fecal Microbiome Transplant (FMT) Study for Anorexia Nervosa Anorexia Nervosa | Recruiting | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 20 | 2026-01-15 | 2026-01-23 | |
| Creatine and Resistance Training in Older Adults With Mild Cognitive Impairment Creatine monohydrate, Resistance training - Creatine, Exercise | Not applicable | Recruiting | Western University, Canada | 140 | 2026-01-01 | 2026-08-20 |
| The DURATION Study: reDUcing sedentaRy behAviour to Maintain cogniTIve functiON. interrupting sedentary behaviour with light physical activity - Sedentary Behavior, Mild Cognitive Impairment | Not applicable | Withdrawn | Western University, Canada | 2025-12-01 | 2024-03-05 | |
| Enhancing Patient Comfort and Reducing Anxiety During Flexible Cystoscopy and Bladder Instillation in Bladder Cancer Patients: A Randomized Controlled Trial and Observational Study Optimized Timing of Intravesical Lidocaine Gel, Calming Music During Procedure, Visual Distraction with Screen Content - Bladder Cancer | Not applicable | Not yet recruiting | Western University, Canada | 378 | 2025-11-01 | 2025-10-02 |
| Guided ICBT for Adults With Tinnitus in Canada: A Randomized Controlled Trial Internet Delivered Cognitive Behavioural Therapy - Tinnitus | Not applicable | Unknown | Western University, Canada | 82 | 2025-09-15 | 2025-04-13 |
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Motor Activity (26) · Sedentary Behavior (12) · Cognitive Dysfunction (9) · Diabetes Mellitus (9) · Diabetes Mellitus, Type 2 (9) · Dementia (8) · Depression (8) · Obesity (8) · Anxiety Disorders (7) · Cardiovascular Diseases (7) · Osteoarthritis (7) · Parkinson Disease (7) · Psychological Well-Being (6) · Pulmonary Disease, Chronic Obstructive (6) · Inflammation (5)
Exercise (14) · Botulinum Toxins, Type A (5) · Resistance Training (5) · Hematologic Tests (3) · Nutritional Status (3) · Respiratory Function Tests (3) · Tomography, X-Ray Computed (3) · incobotulinumtoxinA (3) · semaglutide (3) · Arthroplasty, Replacement, Hip (2) · Caffeine (2) · Celecoxib (2) · Cognitive Training (2) · Exercise Test (2) · Injections (2)
Canada (243) · United States (6) · United Kingdom (4) · Finland (2) · Italy (2) · Saudi Arabia (2) · Tanzania (2) · Brazil (1) · Germany (1) · Indonesia (1) · Iran (1) · Ireland (1) · Israel (1) · Russia (1) · Rwanda (1)
Grace E Parraga, PhD (9) · Peter Lemon, PhD (9) · Mandar Jog, MD (8) · Harry Prapavessis, Ph.D (6) · Harry Prapavessis, PhD (6) · Michelle F Mottola, PhD (6) · Grace Parraga, PhD (4) · Danielle MacNeil, MD (3) · David A Hess, PhD (3) · James P Dickey, PhD (3) · Liliana Alvarez, PhD (3) · Marc Mitchell, PhD (3) · Subodh Verma, MD, PhD (3) · Anton Skaro, MD PhD (2) · Claire Crooks, PhD (2)
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R01AG055425 (2)