40 unknown. 40 Phase 3, 14 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Phase 3 | 40 | Unknown 40 |
| Phase 2 | 14 | Unknown 14 |
Follow Diabetes Complications: new trials by email Literature Review of Diabetes Complications trials Research Report on Diabetes Complications
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical Outcome of Vinpocetine in Diabetic Nephropathy Vinpocetine, Standard Therapy, Placebo - Diabetic Kidney Disease, Diabetic Nephropathies | Phase 2 / Phase 3 | Unknown | Ain Shams University | 64 | 2024-07-10 | 2024-07-11 |
| A Study to Evaluate Pregabalin in Painful Diabetic Peripheral Neuropathy pregabalin sustained-release tablets, Placebo - Painful Diabetic Neuropathy | Phase 3 | Unknown | CSPC Ouyi Pharmaceutical Co., Ltd. | 358 | 2024-05-15 | 2024-04-30 |
| Long Term Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy Adezunap (AP707), Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Efficacy and Tolerability of AP707 in Patients With Chronic Pain Due to Diabetic Polyneuropathy Adezunap (AP707), Placebo - Pain, Pain Syndrome | Phase 3 | Unknown | Apurano Pharmaceuticals GmbH | 558 | 2023-11-02 | 2024-01-31 |
| Comparison Between the Efficacy of SGLT2 Inhibitor Therapy Versus ACE Inhibitor in the Treatment of Diabetic Kidney Disease Empagliflozin 25 MG, Enalapril Maleate 20 mg - Diabetic Nephropathy Type 2 | Phase 2 / Phase 3 | Unknown | Omar Tarek Elfarargi | 212 | 2023-03-01 | 2022-05-13 |
| Adipose Derived Regenerative Cells In the Treatment of Diabetic Foot Ulcers ADRCs, standard care, Placebo - Diabetic Foot Ulcer | Phase 3 | Unknown | Paracrine, INC. | 290 | 2023-02-28 | 2022-09-28 |
| Effect of SGLT2i on Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients Dapagliflozin 10mg Tab plus another oral hypoglycemic agent, Two oral hypoglycemic agents other than dapagliflozin - Diabetic Retinopathy | Phase 3 | Unknown | Nidae Alaa | 60 | 2022-06-06 | 2022-06-10 |
| Study on Precision Treatment of Diabetic Retinopathy Macular Edema Guided by Real-time OCT During Operation Ranibizumab Injection [Lucentis], Inner limiting membrane stripping, Dexamethasone intravitreal implant - Diabetic Retinopathy | Phase 3 | Unknown | Affiliated Hospital of Nantong University | 60 | 2021-11-15 | 2023-08-01 |
| Efficacy and Safety of Intravitreal Injection of Bevacizumab with and Without Oral Curcumin bevacizumab with oral curcumin, bevacizumab with oral placebo - Diabetic Macular Edema, Macular Edema | Phase 2 / Phase 3 | Unknown | Isfahan University of Medical Sciences | 52 | 2021-10-10 | 2024-09-19 |
| Umbilical Cord Blood Mononuclear Cell Gel in the Treatment of Refractory Diabetic Foot Ulcer Umbilical cord blood mononuclear cell gel（MNC）, The platelet rich plasma（PRP） - Diabetic Foot Ulcer | Phase 3 | Unknown | Peking University Third Hospital | 40 | 2021-03-30 | 2022-09-29 |
| Possible Role of Roflumilast in Diabetic Nephropathy Roflumilast, Placebo - Diabetic Nephropathies | Phase 3 | Unknown | Tanta University | 48 | 2021-03-10 | 2021-02-16 |
| The Benefits of Vitamin D 5000 IU as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient Standard therapy, Vitamin D 5,000IU Oral Tablet - Painful Diabetic Neuropathy | Phase 2 / Phase 3 | Unknown | Duta Wacana Christian University | 60 | 2020-11-03 | 2020-12-30 |
| The Benefits of Astaxanthin as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient Standard therapy, Astaxanthin - Painful Diabetic Neuropathy | Phase 2 / Phase 3 | Unknown | Duta Wacana Christian University | 60 | 2020-11-03 | 2020-12-30 |
| The Benefits of Vitamin B Combination as Add on Therapy in the Management of Painful Diabetic Neuropathy Patient Standard therapy, Vitamin B combination - Painful Diabetic Neuropathy | Phase 2 / Phase 3 | Unknown | Duta Wacana Christian University | 60 | 2020-11-03 | 2020-12-30 |
| Kidney Fat in Type 2 Diabetes and the Effects of Ezetimibe Ezetimibe 10mg, Placebo - Diabetes Mellitus, Type 2, Diabetic Kidney Disease | Phase 3 | Unknown | Steno Diabetes Center Copenhagen | 60 | 2020-10-01 | 2022-01-18 |
| Possible Ameliorating Effect of N- Acetylcysteine (NAC) on Type-II Diabetes Induced Nephropathy N Acetylcysteine - Diabetic Kidney Disease, Diabetes Mellitus, Type 2 | Phase 2 / Phase 3 | Unknown | Al-Azhar University | 60 | 2019-10-01 | 2020-08-28 |
| The Effect of Platelet-Rich Plasma-Fibrin Glue in Combination With Vitamin E and C for Treatment of Non-healing Diabetic Foot Ulcers PRP-Fibrin Glue, Vitamin E and C, Placebo - Diabetic Foot Ulcers, Diabetic Wound | Phase 2 / Phase 3 | Unknown | Mashhad University of Medical Sciences | 24 | 2019-08-28 | 2020-03-20 |
| Effects of Fenofibrate Therapy in Diabetic Nephropathy Fenofibrate - Diabetes Mellitus, Diabetic Nephropathies | Phase 3 | Unknown | Singapore General Hospital | 300 | 2019-03-08 | 2020-12-14 |
| Study of Combined Topical Growth Factor and Protease Inhibitor in Chronic Wound Healing Becaplermin, Promagran Dressing, Placebo Dressing - Venous Ulcer, Foot Ulcer, Diabetic | Phase 3 | Unknown | McMaster University | 80 | 2018-08-01 | 2018-04-09 |
| Efficacy, Safety and Response Predictors of Adjuvant Astragalus Therapy for Diabetic Kidney Disease Astragalus Powder, Routine medical care (active comparator) - Diabetic Nephropathies, Diabetic Kidney Disease | Phase 2 / Phase 3 | Unknown | The University of Hong Kong | 118 | 2018-07-01 | 2020-12-07 |
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Diabetic Neuropathies (13) · Diabetic Foot (9) · Diabetic Nephropathies (9) · Diabetic Retinopathy (8) · Diabetes Mellitus (6) · Neuralgia (4) · Pain (4) · Agnosia (2) · Chronic Pain (2) · Diabetes Mellitus, Type 2 (2) · Macular Edema (2) · Marijuana Abuse (2) · Peripheral Nervous System Diseases (2) · Somatoform Disorders (2) · Arterial Occlusive Diseases (1)
Endocrine System Diseases (40) · Diabetes Mellitus (34) · Cardiovascular Diseases (17) · Diabetic Angiopathies (17) · Vascular Diseases (17) · Nervous System Diseases (13) · Neuromuscular Diseases (13) · Peripheral Nervous System Diseases (11) · Pathological Conditions, Signs and Symptoms (10) · Diabetic Neuropathies (9) · Female Urogenital Diseases (9) · Female Urogenital Diseases and Pregnancy Complications (9) · Foot Ulcer (9) · Kidney Diseases (9)
Standard of Care (5) · Bevacizumab (3) · Ranibizumab (2) · Acetylcysteine (1) · Becaplermin (1) · Calcitriol (1) · Clonidine (1) · Curcumin (1) · Dexamethasone (1) · Enalapril (1) · Ezetimibe (1) · Fenofibrate (1) · Huang Qi (1) · Ketamine (1) · Pregabalin (1)
Duta Wacana Christian University (3) · Apurano Pharmaceuticals GmbH (2) · The University of Hong Kong (2) · Advanced Magnetic Research Institute International (1) · Affiliated Hospital of Nantong University (1) · Ain Shams University (1) · Al-Azhar University (1) · Biolight AB (1) · CSPC Ouyi Pharmaceutical Co., Ltd. (1) · Diabetes Schwerpunktpraxis (1) · Federal University of São Paulo (1) · Franziskus-Krankenhaus (1) · Global Cell Med (1) · Hamad Medical Corporation (1) · Irmandade da Santa Casa de Misericordia de Sao Paulo (1)
Germany (4) · Canada (3) · China (3) · Egypt (3) · Indonesia (3) · Iran (3) · Brazil (2) · Hong Kong (2) · United States (2) · Denmark (1) · India (1) · Mexico (1) · Qatar (1) · Singapore (1) · South Korea (1)
Rizaldy T Pinzon, MD, MSc, PhD (2) · Alin O Stirban, MD, PhD (1) · Berthold Amann, MD (1) · Chia-I Tsai, master (1) · Chuthamanee Suthisisang, PhD. (1) · Cory Toth, MD (1) · Daryoush Hamidi Alamdari, Ph.D (1) · Desire Cox, MD (1) · Hamid Ahmadieh, MD (1) · Hisham M Elnahhas, Pharm D (1) · Hong Chang Tan, MBBS (1) · Huda M. Salem, PhD (1) · Hugo Quiroz-Mercado, MD (1) · Jan Apelqvist, M.D., Ph.D. (1)
PMID 27496229, PMID 29665833, PMID 29703712, PMID 33436470, PMID 33646060, PMID 34984028, PMID 35587172, PMID 36445944, PMID 37307005, PMID 38810556, PMID 41687084