Deglutition Disorders: Clinical Trials

11 trials for Deglutition Disorders, newest first

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11 terminated. 11 Phase 3, 3 Phase 2.

By phase and status

PhaseTrialsStatus
Phase 311Terminated 11
Phase 23Terminated 3

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Trials (filtered) newest first · largest first

All 11 trials

Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.

TrialPhaseStatusSponsorEnrollmentStartUpdated
The Effect of IV NSAID's and Corticosteroids on Dysphasia and Dysphonia Following ASDF
Intravenous Ketorolac, Intravenous Dexamethasone, Placebo - Dysphagia, Dysphonia
Phase 3TerminatedUniversity of Nebraska332021-01-022024-08-23
Efficacy and Safety of DLBS2411 in the Management of GERD
Omeprazole, DLBS2411, Placebo capsule of Omeprazole - Gastroesophageal Reflux Disease (GERD)
Phase 3TerminatedDexa Medica Group322018-08-162021-01-07
A Trial of IW-3718 for 8 Weeks in Patients With Persistent Gastroesophageal Reflux Disease (GERD) Receiving Proton Pump Inhibitors (PPIs)
IW-3718, placebo, Standard-dose PPIs QD - Gastroesophageal Reflux Disease (GERD)
Phase 3TerminatedIronwood Pharmaceuticals, Inc.4952018-06-202021-08-19
Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease
Adrabetadex - Niemann-Pick Disease, Type C
Phase 2 / Phase 3TerminatedMandos LLC662015-12-232023-08-29
Exparel as a Nerve Block for Severe Hand Pain
liposomal bupivacaine - CREST Syndrome, Peripheral Vascular Disease
Phase 2 / Phase 3TerminatedJose Soberon, MD132014-11-012024-05-21
Evaluation of Transcutaneous Electrical Stimulation in Post Stroke Dysphagia
Urostim I stimulation - Oropharyngeal Dysphagia, Deglutition Disorders
Phase 3TerminatedUniversity Hospital, Rouen22014-06-012016-08-17
Compound Sodium Alginate Oral Suspension Sachet 4-hour Esophageal pH Study in GERD Patients
Compound Sodium Alginate Oral Suspension sachet, Matched placebo - Gastro-esophageal Reflux Disease (GERD)
Phase 3TerminatedReckitt Benckiser Healthcare (UK) Limited162014-04-012017-10-06
Endoscopic Fundoplication Versus Proton Pump Inhibitors for GERD Treatment
Transoral Incisionless Fundoplication, Proton Pump Inhibitors; active control - Gastroesophageal Reflux Disease (GERD)
Phase 3TerminatedUniversity of Pittsburgh602009-03-012018-03-30
Clopidogrel and the Optimization of Gastrointestinal Events (COGENT-1)
CGT-2168 (clopidogrel 75 mg/omeprazole 20 mg) and aspirin, Plavix (clopidogrel 75 mg) and aspirin - Acute Coronary Syndrome, Myocardial Infarction
Phase 3TerminatedCogentus Pharmaceuticals50002007-12-012009-01-28
Elucidation of Acid-Induced Pulmonary Inflammation
lansoprazole, placebo - Gastroesophageal Reflux, Asthma
Phase 2 / Phase 3TerminatedUniversity of Utah172006-08-012016-08-05
Randomized Study of Two Interventions for Liquid Aspiration: Short-Term and Long-Term Effects
Chin-down position, Thickened liquid administration - Pneumonia, Aspiration
Phase 3TerminatedNational Institute on Deafness and Other Communication Disorders (NIDCD)6002006-04-24

Narrower conditions

Gastroesophageal Reflux (6)  ·  Peripheral Vascular Diseases (2)  ·  Acute Coronary Syndrome (1)  ·  Asthma (1)  ·  CREST Syndrome (1)  ·  Cerebrovascular Disorders (1)  ·  Cognitive Dysfunction (1)  ·  Coronary Artery Disease (1)  ·  Coronary Thrombosis (1)  ·  Dementia (1)  ·  Disease (1)  ·  Duodenal Obstruction (1)  ·  Duodenal Ulcer (1)  ·  Dyspepsia (1)

Broader conditions

Digestive System Diseases (11)  ·  Esophageal Diseases (11)  ·  Gastrointestinal Diseases (11)  ·  Esophageal Motility Disorders (7)  ·  Nervous System Diseases (4)  ·  Otorhinolaryngologic Diseases (4)  ·  Pathological Conditions, Signs and Symptoms (4)  ·  Pharyngeal Diseases (4)  ·  Signs and Symptoms (4)  ·  Brain Diseases (3)  ·  Central Nervous System Diseases (3)  ·  Respiratory Tract Diseases (3)  ·  Cardiovascular Diseases (2)  ·  Embolism and Thrombosis (2)

Interventions

Omeprazole (3)  ·  Lansoprazole (2)  ·  2-Hydroxypropyl-beta-cyclodextrin (1)  ·  4-nitro-3-dimethylaminopropiophenone (1)  ·  Aspirin (1)  ·  Clopidogrel (1)  ·  Cyclodextrins (1)  ·  Esomeprazole (1)  ·  Pantoprazole (1)  ·  Proton Pump Inhibitors (1)  ·  Rabeprazole (1)

Sponsors

Cogentus Pharmaceuticals (1)  ·  Dexa Medica Group (1)  ·  Ironwood Pharmaceuticals, Inc. (1)  ·  Jose Soberon, MD (1)  ·  Mandos LLC (1)  ·  National Institute on Deafness and Other Communication Disorders (NIDCD) (1)  ·  Reckitt Benckiser Healthcare (UK) Limited (1)  ·  University Hospital, Rouen (1)  ·  University of Nebraska (1)  ·  University of Pittsburgh (1)  ·  University of Utah (1)

Countries

United States (7)  ·  France (3)  ·  Australia (2)  ·  Canada (2)  ·  Germany (2)  ·  Bulgaria (1)  ·  Chile (1)  ·  China (1)  ·  Czechia (1)  ·  Hungary (1)  ·  Indonesia (1)  ·  Italy (1)  ·  Mexico (1)  ·  Netherlands (1)  ·  New Zealand (1)

Top investigators

Blair A Jobe, MD (1)  ·  Dadang Makmun, SpPD, KGEH (1)  ·  Dolvy Girawan, M. Kes., SpPD, KGEH (1)  ·  Dr. Jeri Logemann (1)  ·  Dr. Joanne Robbins (1)  ·  Hery D. Purnomo, SpPD, KGEH (1)  ·  Iswan A. Nusi, Prof. KGEH, FINASIM, FACG (1)  ·  Jose Soberon, MD (1)  ·  Kathryn Peterson, MD (1)  ·  Kevin Garvin, MD (1)  ·  Mike Shetzline, MD, PhD (1)  ·  Nicole D Bouvy, MD, PhD (1)  ·  Pablo Lapuerta, MD (1)

Results publications

PMID 18378947, PMID 20925534, PMID 27012778

NIH funding

2015 (1), U01DC003206 (1)