3 completed, 2 terminated, 1 withdrawn. 4 Phase 2, 3 Phase 3, 1 Not applicable, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 4 | Completed 2, Terminated 2 |
| Phase 3 | 3 | Terminated 2, Completed 1 |
| Not applicable | 1 | Completed 1 |
| Phase 4 | 1 | Withdrawn 1 |
Follow Cyclodextrins: new trials by email Literature Review of Cyclodextrins trials Research Report on Cyclodextrins
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Open-label Study of VTS-270 in Participants With Neurologic Manifestations of Niemann-Pick Type C1 VTS-270 - Niemann-Pick Disease, Type C | Phase 2 / Phase 3 | Terminated | Mandos LLC | 2 | 2019-12-02 | 2023-12-26 |
| Effect of Cyclodextrin on Sensory Nerve Activity: A Novel Anti-tussive Therapy cyclodextrin - Cough | Phase 4 | Withdrawn | Imperial College London | 2016-08-01 | 2019-05-23 | |
| SFX-01 After Subarachnoid Haemorrhage SFX-01, Placebo - Subarachnoid Hemorrhage, Spontaneous | Phase 2 | Completed | Evgen Pharma | 90 | 2016-04-01 | 2020-01-18 |
| Adrabetadex to Treat Niemann-Pick Type C1 (NPC1) Disease Adrabetadex - Niemann-Pick Disease, Type C | Phase 2 / Phase 3 | Terminated | Mandos LLC | 66 | 2015-12-23 | 2023-08-29 |
| VTS-270 to Treat Niemann-Pick Type C1 (NPC1) Disease Parts A/B: Adrabetadex, Parts A/B: Sham Control - Niemann-Pick Disease, Type C | Phase 2 / Phase 3 | Completed | Mandos LLC | 56 | 2015-10-01 | 2023-02-22 |
| Vascular Impact of Omega-3 in Metabolic Syndrome omega-3 from vegetal origin, Placebo - Essential Hypertension, Metabolic Syndrome | Not applicable | Completed | University Hospital, Rouen | 95 | 2011-01-01 | 2026-04-16 |
Niemann-Pick Disease, Type C (3) · Cognitive Dysfunction (2) · Deglutition Disorders (2) · Disease (2) · Mobility Limitation (2) · Cough (1) · Essential Hypertension (1) · Metabolic Syndrome (1) · Subarachnoid Hemorrhage (1)
Mandos LLC (3) · Evgen Pharma (1) · Imperial College London (1) · University Hospital, Rouen (1)
United Kingdom (4) · France (3) · Australia (2) · Germany (2) · New Zealand (2) · Singapore (2) · Turkey (Türkiye) (2) · United States (2) · Costa Rica (1) · Spain (1) · Switzerland (1)
Diederik Bulters, MBChB, BSc (1) · O S Usmani, MD, PhD (1) · Robinson Joannides, MD, PhD (1)
PMID 32217557, PMID 34791007, PMID 39028412, PMID 40525490
2015 (2), 2014 (1)