17 completed, 5 unknown, 4 active not recruiting, 4 terminated. 18 Not applicable, 2 Phase 4, 1 Phase 1, 1 Phase 2.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 18 | Completed 9, Unknown 4, Terminated 3, Recruiting 1, Withdrawn 1 |
| Phase 4 | 2 | Completed 1, Withdrawn 1 |
| Phase 1 | 1 | Withdrawn 1 |
| Phase 2 | 1 | Withdrawn 1 |
Follow Degenerative Joint Disease: new trials by email Literature Review of Degenerative Joint Disease trials Research Report on Degenerative Joint Disease
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Zimmer Biomet Shoulder Arthroplasty PMCF Study Alliance™ Glenoid - Shoulder Fractures, Shoulder Arthritis Osteoarthritis | Recruiting | Zimmer Biomet | 50 | 2025-04-29 | 2026-06-08 | |
| MRI of the TMJ in Patients With DJD MRI, Magnetic Resonance Imaging - Degenerative Joint Disease, Control Subjects | Active not recruiting | University of Minnesota | 40 | 2025-04-17 | 2026-06-18 | |
| Exploring the Relationship Between Occlusion and Degenerative TMJ Disorders: A Comparative Clinical Study Occlusal Splint and Bite Correction Therapy, Conventional TMJ Therapy, Routine TMJ Care (Medication Only) - Degenerative Joint Disease, TMD | Not applicable | Completed | King Khalid University | 150 | 2025-01-10 | 2025-05-07 |
| A Multi-Centre Study in Patients Undergoing Total Hip Arthroplasty With the Smith+Nephew CATALYSTEM™ Primary Hip System CATALYSTEM - Total Hip Arthroplasty (THA), Osteoarthritis | Active not recruiting | Smith & Nephew, Inc. | 119 | 2024-09-26 | 2026-03-12 | |
| Hyaluronic Acid and Adelmidrol (Hyadrol®) in Patients With Degenerative Joint Disease Hyadrol® - Degenerative Joint Disease | Not applicable | Unknown | University of Roma La Sapienza | 59 | 2024-07-16 | 2024-07-18 |
| Prevalence of Musculoskeletal Complaints in Nursing Home Residents Rheumatoid Arthritis, Rheumatic Diseases | Completed | Maastricht University Medical Center | 100 | 2024-01-18 | 2025-09-30 | |
| Safety and Effectiveness of the HIT Reverse HRS Hip Innovation Technology Reverse Hip Replacement System, Already-marketed semi-constrained uncemented hip systems using a metal-on-XLPE or ceramic-on-XLPE bearing combination. - Degenerative Joint Disease, Osteoarthritis, Hip | Not applicable | Recruiting | Hip Innovation Technology | 288 | 2022-07-15 | 2026-09-21 |
| Post Marketing Clinical Follow up Study to Evaluate the Performance and Safety of HYALEXO Osteoarthritis, Degenerative Joint Disease | Unknown | Yooyoung Pharmaceutical Co., Ltd. | 54 | 2022-05-01 | 2022-04-19 | |
| Postmarketing Multicenter Study of Intra-Articular DIART ONE / EASYGO ONE for Knee Osteoarthritis Knee Osteoarthritis, Osteoarthritis of the Knee | Completed | Yuria-Pharm | 55 | 2021-08-14 | 2025-04-15 | |
| Prospective Post-market Study Examining the Effectiveness of the EcoFit® EcoFit® Total Hip System with implacross® E Polyethylene - Degenerative Joint Disease, Femoral Fracture | Not yet recruiting | Implantcast North America, LLC | 500 | 2021-06-21 | 2021-06-09 | |
| Whether Proton Pump Inhibitors, Administered Prior to or After Surgery, Can Reduce the Incidence and/or Severity of Difficulty Swallowing Foods and/or Liquids,Following Anterior Cervical Surgery Esomeprazole, Placebo Oral Tablet - Dysphagia, GERD | Phase 2 | Withdrawn | Icahn School of Medicine at Mount Sinai | 2020-07-01 | 2020-11-23 | |
| R3 Delta Ceramic Acetabular System PAS U.S. R3 Biolox Delta Ceramic Acetabular System - Degenerative Joint Disease | Completed | Smith & Nephew, Inc. | 189 | 2018-02-07 | 2025-04-13 | |
| Cellular & Biocellular Regenerative Therapy in Musculoskeletal Pain, Dysfunction,Degenerative or Inflammatory Disease Normal Saline, Tissue Stromal Vascular Fraction, Platelet Rich Plasma - Osteoarthritis, Rheumatoid Nodule | Not applicable | Unknown | Robert W Alexander, MD | 300 | 2017-03-11 | 2020-01-18 |
| Comparative Effectiveness of an Activity-specific Monitoring Device- StepRite Steprite™, Standard of care - Osteoarthritis, Degenerative Joint Disease | Not applicable | Terminated | Texas Tech University Health Sciences Center | 9 | 2016-10-21 | 2019-08-09 |
| Study Comparing Regional Anesthetic Blocks and Periarticular Infiltration for the Management of Post-operative Pain After Direct Anterior Total Hip Arthroplasty L2 paravertebral block, periarticular injection group - Degenerative Joint Disease | Not applicable | Terminated | Mayo Clinic | 9 | 2016-05-01 | 2016-11-16 |
| Efficacy of Intraoperative Injections on Postoperative Pain Control During Total Hip Replacement Bupivicaine + epinephrine, Bupivacaine, Ropivacaine - Osteoarthritis, Degenerative Joint Disease | Phase 4 | Withdrawn | Rush University Medical Center | 2016-04-30 | 2022-10-27 | |
| Postoperative Hip Precautions After Total Hip Arthroplasty Via the Posterior Approach: A Prospective Randomized Trial Hip Precautions, No Hip Precautions - Osteoarthritis, Degenerative Joint Disease | Not applicable | Completed | Rush University Medical Center | 1133 | 2016-01-01 | 2025-11-14 |
| Post Market Clinical Follow Up of LEGION™ Primary TKS With VERILAST™ LEGION™ Primary TKS with VERILAST™ Bearing Surface - Degenerative Joint Disease | Active not recruiting | Smith & Nephew, Inc. | 163 | 2015-09-01 | 2025-12-15 | |
| Navigation With X3 vs Non-Navigation With X3 Study Trident X3 Insert with Navigation system, Trident X3 Insert with conventional instrumentation - Degenerative Joint Disease | Not applicable | Completed | Stryker Japan K.K. | 49 | 2015-04-01 | 2018-10-29 |
| Multi-Site, Post-Market Study of the ICONACY I-Hip System Iconacy Hip System - Degenerative Joint Disease | Not applicable | Unknown | Iconacy Orthopedic Implants, LLC. | 500 | 2014-04-01 | 2014-05-06 |
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Joint Diseases (37) · Osteoarthritis (18) · Arthritis (6) · Arthritis, Rheumatoid (3) · Osteoarthritis, Hip (2) · Osteoarthritis, Knee (2) · Osteonecrosis (2) · Agnosia (1) · Ankylosis (1) · Arthralgia (1) · Back Pain (1) · Chronic Pain (1) · Congenital Abnormalities (1) · Connective Tissue Diseases (1) · Deglutition Disorders (1)
Musculoskeletal Diseases (36) · Rheumatic Diseases (21) · Arthritis (16) · Pathological Conditions, Signs and Symptoms (12) · Signs and Symptoms (8) · Neurologic Manifestations (7) · Pain (5) · Skin and Connective Tissue Diseases (5) · Connective Tissue Diseases (4) · Osteoarthritis (4) · Pathologic Processes (4) · Wounds and Injuries (4) · Autoimmune Diseases (3) · Bone Diseases (3) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (3)
Arthroplasty, Replacement, Hip (2) · Bupivacaine (1) · Clonidine (1) · Data Collection (1) · Electrosurgery (1) · Epinephrine (1) · Esomeprazole (1) · Ketorolac (1) · Magnetic Resonance Imaging (1) · Methods (1) · Milnacipran (1) · Motivational Interviewing (1) · Occlusal Splints (1) · Ropivacaine (1) · Saline Solution (1)
Mayo Clinic (3) · Smith & Nephew, Inc. (3) · Brigham and Women's Hospital (2) · Encore Medical, L.P. (2) · Iconacy Orthopedic Implants, LLC. (2) · Rush University Medical Center (2) · Smith & Nephew Orthopaedics AG (2) · Stryker Japan K.K. (2) · Zimmer Biomet (2) · BioMimetic Therapeutics (1) · Dr. Norman Harden (1) · Hip Innovation Technology (1) · Icahn School of Medicine at Mount Sinai (1) · Implantcast North America, LLC (1) · Kaiser Permanente (1)
United States (22) · Netherlands (4) · Germany (3) · Japan (3) · Belgium (2) · Canada (2) · Italy (2) · Spain (2) · United Kingdom (2) · Austria (1) · Denmark (1) · Finland (1) · Norway (1) · Saudi Arabia (1) · Ukraine (1)
Elena Losina, PhD (2) · Mary I O'Connor, MD (2) · Andrew C Hecht, MD (1) · Barry J Waldman, M.D. (1) · Christopher DiGiovanni, MD (1) · Donald L Pomeroy, MD (1) · Emilie Rohmer (1) · Fabio Catani, Prof (1) · Gary D. Botimer, M.D. (1) · George W Brindley, MD (1) · Gijs Van Hellemondt, MD (1) · Glenn C Terry, MD (1) · Husam G Elias, MD, DMD (1) · Jan Victor, Prof (1) · Jerome Porterie, Dr (1)
PMID 22437996, PMID 23824386, PMID 25848134, PMID 26566324, PMID 26714179, PMID 27585441, PMID 28732147, PMID 36269595
R21AR063913 (1)