57 completed, 10 terminated, 8 recruiting, 8 unknown. 93 Phase 3, 16 Phase 2.
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Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Perioperative Dexmedetomidine to Reduce Post-procedure Grief Following Second-trimester Dilation and Evacuation Dexmedetomidine (IV) 0.5 mcg/kg, Placebo - Abortion, Stillbirth | Phase 2 / Phase 3 | Withdrawn | Stanford University | 2026-07-01 | 2026-07-17 | |
| Asymptomatic Bacteriuria in Pregnancy in Low- and Middle-IncomE Countries Oral nitrofurantoin monohydrate/macrocrystals, Placebo - Preterm Birth, Small for Gestational Age (SGA) | Phase 3 | Recruiting | NICHD Global Network for Women's and Children's Health | 1134 | 2025-12-08 | 2026-01-22 |
| RGX-121-3102 Gene Therapy in Participants With MPS II (Hunter Syndrome) RGX-121-3102 - MPS II, Hunter Syndrome (MPS II) | Phase 3 | Active not recruiting | REGENXBIO Inc. | 2 | 2025-11-25 | 2026-06-04 |
| Early Double Sequential Defibrillation in Out of Hospital Cardiac Arrest Double sequential defibirllation, Standard defibrillation - Out of Hospital Cardiac Arrest, Ventricular Fibrillation | Phase 2 / Phase 3 | Recruiting | Gabriel Riva | 916 | 2025-09-08 | 2026-02-17 |
| Aspirin Dose Escalation for the Prevention of Recurrent Preterm Delivery Trial 162mg Aspirin, 81mg Aspirin - Preterm Delivery, Obstetrical Complications | Phase 3 | Recruiting | The George Washington University Biostatistics Center | 1800 | 2025-07-01 | 2026-04-09 |
| Effect of Long-term Carvedilol to Prevent Decompensation or Death in Patients With Asymptomatic Child-Pugh A5 to B8 Cirrhosis and Clinically Significant Portal Hypertension: a Multicenter Double-blind Randomized Control Trial Experimental group: Patients will be treated with carvedilol., Control group: Patients will receive a placebo. - Asymptomatic Cirrhosis, Clinically Significant Portal Hypertension | Phase 3 | Not yet recruiting | University Hospital, Tours | 290 | 2025-06-17 | 2025-06-04 |
| Beta-blOckers discoNtinuation in Patients Presenting Heart FaIlure With REcovered Left Ventricular Ejection Fraction Βeta-Blockers discontinued (with tapering) - Heart Failure | Phase 3 | Recruiting | Assistance Publique - Hôpitaux de Paris | 1300 | 2025-02-11 | 2026-01-16 |
| InfasurfAero™ Versus Sham Treatment in Preterm Newborns With RDS Infasurf Aero™ - Respiratory Distress Syndrome (Neonatal), Intubation Complication | Phase 3 | Recruiting | ONY | 220 | 2025-01-01 | 2025-03-30 |
| The Effect of Retatrutide Once Weekly on Cardiovascular Outcomes and Kidney Outcomes in Adults Living With Obesity (TRIUMPH-Outcomes) Retatrutide, Placebo - Atherosclerotic Cardiovascular Disease (ASCVD), Chronic Kidney Disease (CKD) | Phase 3 | Active not recruiting | Eli Lilly and Company | 10000 | 2024-04-30 | 2026-10-08 |
| Calcium Aspirin Multiple Micronutrients (CAMMS) to Reduce Preterm Birth Calcium aspirin multiple micronutrients, Iron-folic Acid - Preterm Labor, Small for Gestational Age at Delivery | Phase 3 | Withdrawn | Johns Hopkins Bloomberg School of Public Health | 2024-04-01 | 2024-04-23 | |
| An Extension Study of the Long-Term Safety, Tolerability, and Efficacy of Tividenofusp Alfa (DNL310) in Participants With Mucopolysaccharidosis Type II (MPS II) From Study DNLI-E-0002 or Study DNLI-E-0007 tividenofusp alfa - Mucopolysaccharidosis II | Phase 2 / Phase 3 | Enrolling by invitation | Denali Therapeutics Inc. | 99 | 2023-09-20 | 2026-11-09 |
| Stroke Prophylaxis With Apixaban in Chronic Kidney Disease Stage 5 Patients With Atrial Fibrillation Apixaban 2.5 milligram Oral Tablet - Chronic Kidney Diseases, Atrial Fibrillation | Phase 3 | Recruiting | Region Stockholm | 1400 | 2023-02-17 | 2024-10-04 |
| Magnesium Sulphate Neuroprotective Strategies for Preterm Deliveries Magnesium sulfate loading with maintenance dose, Magnesium sulfate loading dose only - Premature Birth, NEUROPROTECTION | Phase 2 / Phase 3 | Unknown | Zagazig University | 336 | 2023-01-20 | 2023-07-14 |
| The RENAL LIFECYCLE Trial: A RCT to Assess the Effect of Dapagliflozin on Renal and Cardiovascular Outcomes in Patients With Severe CKD Dapagliflozin 10 mg/day (oral), Placebo - Kidney Disease, Chronic, Renal Transplant Failure | Phase 3 | Active not recruiting | University Medical Center Groningen | 1750 | 2022-11-08 | 2026-10-08 |
| A Study to Determine the Efficacy and Safety of Tividenofusp Alfa (DNL310) vs Idursulfase in Pediatric and Young Adult Participants With Neuronopathic (nMPS II) or Non-Neuronopathic Mucopolysaccharidosis Type II (nnMPS II) tividenofusp alfa, idursulfase - Mucopolysaccharidosis II | Phase 2 / Phase 3 | Active not recruiting | Denali Therapeutics Inc. | 65 | 2022-07-21 | 2026-09-09 |
| A Multi-cohort Study of Safety, Efficacy, PK and PD of GNR-055 in Patients With Mucopolysaccharidosis Type II GNR-055 1.0-2.0-3.0 mg/kg, GNR-055 2.0 mg/kg, GNR-055 3.0 mg/kg - Mucopolysaccharidosis Type II, Metabolic Diseases | Phase 2 / Phase 3 | Active not recruiting | AO GENERIUM | 32 | 2021-11-30 | 2026-09-21 |
| Cardiac Sympathetic Denervation for Prevention of Ventricular Tachyarrhythmias Cardiac Sympathetic Denervation (CSD), Routine Care - Sudden Cardiac Death, Ventricular Tachycardia | Phase 3 | Unknown | University of California, Los Angeles | 40 | 2021-07-26 | 2024-01-19 |
| Preventive VT Substrate Ablation in Ischemic Heart Disease Ventricular tachycardia substrate-based radiofrequency ablation - Ventricular Tachycardia, Ventricular Arrythmia | Phase 3 | Unknown | Centro Medico Teknon | 58 | 2021-06-01 | 2023-08-30 |
| Luteal Support in Artificial Vitrified/Warmed Cycles With Low Progesterone Progesteron TID - IVF, Embryo Loss | Phase 3 | Completed | University Hospital, Ghent | 87 | 2021-04-02 | 2026-03-23 |
| Chronic Hypertension and Acetyl Salicylic Acid in Pregnancy Aspirin 150 mg, Placebo - Chronic Hypertension Complicating Pregnancy, Pre-Eclampsia | Phase 3 | Recruiting | Centre Hospitalier Intercommunal Creteil | 500 | 2021-02-15 | 2026-06-12 |
Showing 20 of 93. Sign in to see all of them.
Death, Sudden, Cardiac (22) · Sudden Infant Death (13) · Cardiovascular Diseases (12) · Mucopolysaccharidosis II (12) · Heart Diseases (11) · Myocardial Infarction (11) · Arrhythmias, Cardiac (10) · Perinatal Death (10) · Premature Birth (10) · Stillbirth (10) · Heart Failure (8) · Tachycardia, Ventricular (7) · Ventricular Fibrillation (7) · Brain Death (5)
Pathologic Processes (93) · Pathological Conditions, Signs and Symptoms (93) · Death, Sudden (37) · Female Urogenital Diseases and Pregnancy Complications (29) · Urogenital Diseases (29) · Nervous System Diseases (28) · Cardiovascular Diseases (26) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (23) · Heart Diseases (23) · Pregnancy Complications (22) · Neurologic Manifestations (19) · Heart Arrest (18) · Vascular Diseases (18) · Neurobehavioral Manifestations (17)
Aspirin (5) · Defibrillators, Implantable (5) · Amiodarone (3) · Misoprostol (3) · Sodium Chloride (3) · Sotalol (3) · idursulfase (3) · Cardiopulmonary Resuscitation (2) · Docosahexaenoic Acids (2) · Folic Acid (2) · Geritol (2) · Iron (2) · Melatonin (2) · Naloxone (2) · Ranolazine (2)
National Heart, Lung, and Blood Institute (NHLBI) (8) · Johns Hopkins Bloomberg School of Public Health (6) · Assistance Publique - Hôpitaux de Paris (5) · NICHD Global Network for Women's and Children's Health (3) · Shire (3) · Brigham and Women's Hospital (2) · Denali Therapeutics Inc. (2) · Gynuity Health Projects (2) · Hospices Civils de Lyon (2) · REGENXBIO Inc. (2) · US Department of Veterans Affairs (2) · University of Calgary (2) · Washington University School of Medicine (2) · AO GENERIUM (1) · Aldagen (1)
United States (33) · France (18) · Canada (13) · Spain (13) · Germany (10) · Italy (10) · United Kingdom (10) · Brazil (9) · Belgium (7) · Netherlands (7) · Sweden (7) · Argentina (6) · Bangladesh (6) · Australia (5) · India (5)
Alfred Hallstrom (2) · Alfred Sommer, M.D. (2) · Kerry Lee (2) · Rajat Dhar, MD (2) · Abdullah H Baqui, MBBS, DrPH (1) · Akil Awad, M.D. Ph.D. (1) · Alain B Labrique, MSc (1) · Alain B. Labrique, MSc (1) · Alain Cariou, MD, PhD (1) · Alejandro Jenik, M.D. (1) · Alexander Schramm (1) · Allan Barker (1) · Ameth Hawkins, MD (1)
PMID 28490513, PMID 12914883, PMID 18371559, PMID 18381485, PMID 18450889, PMID 18644934, PMID 19022547, PMID 19349375, PMID 19581544, PMID 19660420, PMID 19704100, PMID 19752530, PMID 19845951, PMID 19917887, PMID 20362722, PMID 20435345, PMID 20884379, PMID 20941903, PMID 20977661, PMID 21150784, PMID 21156950, PMID 21177506, PMID 21482964, PMID 21510905, PMID 21586714, PMID 21832026, PMID 21956955, PMID 22071710, PMID 22218721, PMID 22322124, PMID 22595385, PMID 22929184, PMID 23071204, PMID 23151532, PMID 23280225, PMID 23303315, PMID 23509175, PMID 23541974, PMID 23837440, PMID 23966331, PMID 24727258, PMID 25209926, PMID 25250647, PMID 25536256, PMID 25589197, PMID 25646326, PMID 25855884, PMID 25985774, PMID 26010524, PMID 26186135
2023 (3), 2014 (2), 2004 (1), 2018 (1), R01HL034071 (1), R01HL036821 (1), R01HL091157 (1), U01DK061700 (1), U01HD043464 (1), U01HD109332 (1), U01HL045700 (1), U01HL048120 (1), U01HL048159 (1), U01HL055766 (1), U01HL067972 (1)