6 completed, 4 recruiting, 2 not yet recruiting, 2 unknown. 2 Not applicable, 1 Phase 1, 1 Phase 3.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 2 | Enrolling by invitation 1, Unknown 1 |
| Phase 1 | 1 | Completed 1 |
| Phase 3 | 1 | Recruiting 1 |
Follow Coarctation of Aorta: new trials by email Literature Review of Coarctation of Aorta trials Research Report on Coarctation of Aorta
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Effects of Exercise in Patients With Repaired Coarctation of the Aorta Outpatient high-intensity interval training (HIIT), Home-based high-intensity interval training (HIIT) - Coarctation of the Aorta, Coarctation of Aorta | Not applicable | Enrolling by invitation | University Medical Centre Ljubljana | 45 | 2026-08-01 | 2026-08-25 |
| Impact of Aortic Geometry on Vascular Remodeling After Stent Implantation in Coarctation of the Aorta CT aortography, CMR - Aortic Geometry, Vascular Remodeling | Not yet recruiting | Assiut University | 50 | 2025-09-01 | 2025-08-20 | |
| Cardiovascular Risk in Children With Chronic Conditions Study Kidney Transplant, Familial Hypercholesterolaemia | Recruiting | Semmelweis University | 300 | 2025-04-01 | 2025-08-08 | |
| A Study of Angiotensin-II Receptor Blocker on Cardiovascular Remodeling (VALUE Trial) Losartan, Amlodipine, Placebo - Coarctation of Aorta, High Blood Pressure | Phase 3 | Recruiting | Mayo Clinic | 120 | 2024-04-01 | 2026-09-11 |
| Happy Baby Hearts Study Continuous Renal NIRS Monitoring, Standard Clinical Care, Satisfaction Survey - Coarctation of Aorta | Completed | University of Wisconsin, Madison | 82 | 2023-04-19 | 2025-03-10 | |
| An Integrated Prenatal and Postnatal Treatment Model for the Treatment of Newborns With Critical Congenital Heart Disease Congenital Heart Disease, Coarctation of Aorta | Recruiting | Beijing Anzhen Hospital | 10000 | 2022-01-01 | 2025-01-10 | |
| Antibiotic Prophylaxis for TEVAR thoracic endovascular aortic repair - Aortic Dissection, Aortic Diseases | Terminated | First Affiliated Hospital of Zhejiang University | 457 | 2022-01-01 | 2025-09-25 | |
| Canadian Adult Congenital Heart Disease Intervention Registry Participants undergoing ACHD intervention - Atrial Septal Defect, Patent Foramen Ovale | Not yet recruiting | University Health Network, Toronto | 9000 | 2020-04-01 | 2020-02-28 | |
| NIRS in Congenital Heart Defects - Correlation With Echocardiography NIRS evaluation - Congenital Heart Defect, Single-ventricle | Recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 100 | 2019-10-11 | 2025-06-17 | |
| PV Loop & Coarctation Study Pressure-volume loop catheter - Coarctation of Aorta | Active not recruiting | University of Minnesota | 21 | 2019-06-04 | 2026-04-08 | |
| Prognosis and Integrative Assessment of Aortic Coarctation Patients in China Coarctation of Aorta | Unknown | Beijing Institute of Heart, Lung and Blood Vessel Diseases | 300 | 2019-03-01 | 2020-07-14 | |
| Antenatal Diagnosis of Coarctations of the Aorta. Ultrasound - Coarctation of Aorta | Completed | Hospices Civils de Lyon | 20 | 2017-09-01 | 2019-05-14 | |
| The Effect of Paravertebral Block With Dexamethasone on Intraoperative and Postoperative Analgesia in Children Undergoing Surgery for Coarctation of Aorta Dexamethasone, ultrasound, paravertebral block - Coarctation of Aorta | Phase 1 | Completed | Cairo University | 50 | 2016-10-30 | 2017-07-19 |
| Clinical Assessment of Perfusion Techniques During Repair of Coarctation With Aortic Arch Hypoplasia in Infants Surgical repair of coarctation of aorta - Coarctation of Aorta | Not applicable | Unknown | Meshalkin Research Institute of Pathology of Circulation | 45 | 2016-07-01 | 2018-09-07 |
| Cardiac Remodeling and Circulating Biomarkers in Pediatric Left Ventricular Pressure Loading Lesions Echocardiogram, Serology - Coarctation of Aorta, Aortic Stenosis | Completed | University of Colorado, Denver | 31 | 2015-08-01 | 2021-01-19 | |
| Four-limb Blood Pressures in Infants With High Risk of Congenital Malformation of Aorta four-limb blood pressure measurements - Congenital Heart Disease in Children, Coarctation of Aorta | Completed | Guangdong Provincial People's Hospital | 1604 | 2013-01-01 | 2021-09-01 | |
| Reproduction and Survival After Cardiac Defect Repair Cardiovascular Diseases, Heart Diseases | Completed | National Heart, Lung, and Blood Institute (NHLBI) | 1986-07-01 | 2016-02-18 |
Aortic Coarctation (17) · Heart Defects, Congenital (6) · Transposition of Great Vessels (5) · Aortic Valve Stenosis (4) · Tetralogy of Fallot (4) · Heart Septal Defects, Atrial (2) · Hypertension (2) · Hypoplastic Left Heart Syndrome (2) · Pulmonary Atresia (2) · Pulmonary Valve Stenosis (2) · Univentricular Heart (2) · Aortic Aneurysm, Thoracic (1) · Aortic Diseases (1) · Aortic Dissection (1) · Cardiomegaly (1)
Cardiovascular Abnormalities (17) · Congenital Abnormalities (17) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (17) · Cardiovascular Diseases (16) · Heart Diseases (16) · Heart Defects, Congenital (11) · Heart Valve Diseases (5) · Aortic Valve Disease (4) · Heart Septal Defects (4) · Pathological Conditions, Signs and Symptoms (4) · Vascular Diseases (4) · Ventricular Outflow Obstruction (4) · Pathologic Processes (3) · Genetic Diseases, Inborn (2) · Lung Diseases (2)
Ultrasonography (2) · Amlodipine (1) · Bupivacaine (1) · Calcium Dobesilate (1) · Dexamethasone (1) · Echocardiography (1) · Endovascular Aneurysm Repair (1) · Losartan (1) · Saline Solution (1) · Sodium Chloride (1)
Assiut University (1) · Beijing Anzhen Hospital (1) · Beijing Institute of Heart, Lung and Blood Vessel Diseases (1) · Cairo University (1) · First Affiliated Hospital of Zhejiang University (1) · Guangdong Provincial People's Hospital (1) · Hospices Civils de Lyon (1) · Mayo Clinic (1) · McGill University Health Centre/Research Institute of the McGill University Health Centre (1) · Meshalkin Research Institute of Pathology of Circulation (1) · National Heart, Lung, and Blood Institute (NHLBI) (1) · Semmelweis University (1) · University Health Network, Toronto (1) · University Medical Centre Ljubljana (1) · University of Colorado, Denver (1)
United States (4) · China (3) · Canada (2) · Egypt (2) · France (1) · Hungary (1) · Russia (1) · Slovenia (1)
Alexander Egbe, MBBS, MPH (1) · Benjamin S Frank, MD (1) · Eric Horlick, MD (1) · Gabriel Altit (1) · Gurumurthy Hiremath (1) · Jie DU, PhD (1) · Lusine Abrahamyan, MD, PhD (1) · Matthew Harer, MD (1) · Salwa Demitry Roshdy, Professor (1) · Tamas Kiss, MD, PhD (1) · Yifei Wang, MD (1)
PMID 11867038, PMID 15474701, PMID 17059930, PMID 18622223, PMID 25559379, PMID 27084076, PMID 29940971, PMID 30501611, PMID 30585428, PMID 31730044, PMID 32446921, PMID 32547712, PMID 34253175, PMID 41491678
R01HL039052 (1), R01HL162830 (1)