30 completed, 9 recruiting, 4 unknown, 3 active not recruiting. 16 Not applicable, 4 Phase 2, 4 Phase 3, 3 Phase 1, 1 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 16 | Completed 7, Recruiting 4, Unknown 2, Withdrawn 2, Active not recruiting 1 |
| Phase 2 | 4 | Completed 4 |
| Phase 3 | 4 | Completed 4 |
| Phase 1 | 3 | Completed 2, Recruiting 1 |
| Phase 4 | 1 | Completed 1 |
Follow Transposition of Great Vessels: new trials by email Literature Review of Transposition of Great Vessels trials Research Report on Transposition of Great Vessels
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Cardiovascular Risk in Children With Chronic Conditions Study Kidney Transplant, Familial Hypercholesterolaemia | Recruiting | Semmelweis University | 300 | 2025-04-01 | 2025-08-08 | |
| Investigation of Tetralogy of Fallot in Neonates corrective surgery within 28 days of birth, corrective surgery between 3-6 months of age - Tetralogy of Fallot (TOF), Pulmonary Stenosis | Not applicable | Recruiting | Beijing Anzhen Hospital | 160 | 2025-03-01 | 2026-10-13 |
| MASA Valve Early Feasibility Study Surgical Right Ventricular Outflow Tract Reconstruction - Tetrology of Fallot, Pulmonary Stenosis | Not applicable | Recruiting | PECA Labs | 10 | 2023-05-18 | 2024-11-06 |
| Effects Branch PA Stenting d-TGA, ToF and TA Percutaneous intervention (stent) for PA stenosis - Transposition of Great Vessels, Tetralogy of Fallot | Not applicable | Recruiting | UMC Utrecht | 56 | 2023-04-18 | 2025-03-30 |
| Adult Congenital Heart Disease International EValuation of the Effectiveness of SGLT2i Registry SGLT2 inhibitors - Adult Congenital Heart Disease, Congenital Heart Disease | Recruiting | Leiden University Medical Center | 400 | 2023-01-01 | 2026-02-13 | |
| Beta-blocker Administration for Cardiomyocyte Division N-thymidine, Urine Collection, Echocardiogram - Tetralogy of Fallot, Double Outlet Right Ventricle | Phase 1 | Recruiting | Weill Medical College of Cornell University | 40 | 2022-12-16 | 2025-11-18 |
| Cardiovascular Magnetic Resonance in Adults With SysTemic Right Ventricle (STAR) Transposition of Great Arteries | Unknown | IRCCS Policlinico S. Donato | 30 | 2022-11-29 | 2023-01-25 | |
| Cardiac Resynchronization Therapy in Adult Congenital Heart Disease With Systemic Right Ventricle: RIGHT-CRT CRT ON (biventricular pacing) / CRT OFF (inactive or univentricular pacing), CRT OFF (inactive or univentricular pacing) / CRT ON (biventricular pacing) - Congenital Heart Disease, Systemic Right Ventricle | Not applicable | Completed | Assistance Publique - Hôpitaux de Paris | 26 | 2022-11-15 | 2026-06-30 |
| Genetics of Ventriculo-arterial Discordance Genetic analyses: whole genome sequencing - Heart Defects, Congenital | Not applicable | Active not recruiting | Nantes University Hospital | 600 | 2022-09-07 | 2025-12-11 |
| Systemic Right Ventricle Long-term Outcome Transposition of the Great Arteries, Systemic Right Ventricle | Completed | University Medical Center Groningen | 542 | 2022-08-26 | 2024-02-14 | |
| An Integrated Prenatal and Postnatal Treatment Model for the Treatment of Newborns With Critical Congenital Heart Disease Congenital Heart Disease, Coarctation of Aorta | Recruiting | Beijing Anzhen Hospital | 10000 | 2022-01-01 | 2025-01-10 | |
| Influence of Timing of Switch Operation in Transposition of Great Arteries Transposition of Great Vessels | Completed | Brugmann University Hospital | 151 | 2021-12-15 | 2022-07-20 | |
| Targeting Normoxia in Neonates With Cyanotic Congenital Heart Disease in the Intra-operative and Immediate Post-operative Period Normoxia (with controlled re-oxygenation), Standard of care ventilation - Hypoplastic Left Heart Syndrome, Total Anomalous Pulmonary Venous Return | Not applicable | Completed | University of Michigan | 29 | 2021-01-18 | 2024-06-18 |
| A Retrospective Comparison of the Efficacy and Safety of Celsior® in Pediatric Cardiac Surgery for Transposition of the Great Vessels CELSIOR® group, Saint-Thomas group - Transposition of Great Vessels | Unknown | Hospices Civils de Lyon | 200 | 2020-09-01 | 2020-11-06 | |
| Canadian Adult Congenital Heart Disease Intervention Registry Participants undergoing ACHD intervention - Atrial Septal Defect, Patent Foramen Ovale | Not yet recruiting | University Health Network, Toronto | 9000 | 2020-04-01 | 2020-02-28 | |
| Outcomes of Transposition of the Great Arteries After Arterial Switch Operation The arterial switch operation - Transposition of Great Vessels, Outcome, Fatal | Completed | Children's Hospital of Fudan University | 1281 | 2019-12-01 | 2021-10-22 | |
| NIRS in Congenital Heart Defects - Correlation With Echocardiography NIRS evaluation - Congenital Heart Defect, Single-ventricle | Recruiting | McGill University Health Centre/Research Institute of the McGill University Health Centre | 100 | 2019-10-11 | 2025-06-17 | |
| Comprehensive Long-term Follow up of Adults With Arterial Switch Operation No intervention is planed - Transposition of Great Vessels | Active not recruiting | University of Zurich | 540 | 2019-10-01 | 2022-11-08 | |
| Initiation of Resuscitation While Attached to the Cord With Congenital Heart Disease Initiation of Resuscitation While Attached to the Cord - Congential Absence of Heart Structure, Congenital Malformation of Heart, Unspecified | Not applicable | Withdrawn | University of Alberta | 2018-12-18 | 2020-03-24 | |
| Acute Maternal Hyperoxygenation for Fetal Transposition of the Great Arteries (TGA) Oxygen gas - TGA - Transposition of Great Arteries | Not applicable | Completed | The Hospital for Sick Children | 34 | 2018-09-20 | 2026-04-28 |
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Heart Defects, Congenital (23) · Tetralogy of Fallot (13) · Double Outlet Right Ventricle (7) · Truncus Arteriosus, Persistent (7) · Aortic Coarctation (6) · Heart Septal Defects, Ventricular (6) · Hypoplastic Left Heart Syndrome (6) · Pulmonary Valve Stenosis (6) · Congenitally Corrected Transposition of the Great Arteries (5) · Heart Diseases (4) · Pulmonary Atresia (4) · Aortic Valve Stenosis (3) · Cardiovascular Diseases (3) · Heart Failure (3)
Cardiovascular Abnormalities (48) · Congenital Abnormalities (48) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (48) · Cardiovascular Diseases (46) · Heart Diseases (45) · Heart Defects, Congenital (26) · Heart Septal Defects (16) · Heart Valve Diseases (8) · Aortopulmonary Septal Defect (7) · Ventricular Outflow Obstruction (7) · Pathological Conditions, Signs and Symptoms (6) · Heart Septal Defects, Ventricular (5) · Vascular Diseases (5) · Vascular Malformations (5)
Cardiopulmonary Bypass (2) · Acetylcysteine (1) · Aging (1) · Blood Specimen Collection (1) · Cardiac Resynchronization Therapy (1) · Cardiac Surgical Procedures (1) · Dexmedetomidine (1) · Diagnostic Imaging (1) · Eplerenone (1) · Epoetin Alfa (1) · Erythropoietin (1) · Exercise (1) · High-Energy Shock Waves (1) · Magnetic Resonance Imaging (1) · Methods (1)
Boston Children's Hospital (3) · Hospital Universitari Vall d'Hebron Research Institute (3) · National Heart, Lung, and Blood Institute (NHLBI) (3) · Assistance Publique - Hôpitaux de Paris (2) · Beijing Anzhen Hospital (2) · Emory University (2) · Oslo University Hospital (2) · University of Michigan (2) · Bambino Gesù Hospital and Research Institute (1) · Baylor College of Medicine (1) · Bentong Yu (1) · Brugmann University Hospital (1) · Carelon Research (1) · Children's Hospital of Fudan University (1) · Children's National Research Institute (1)
United States (16) · France (6) · Canada (5) · China (4) · Netherlands (4) · Spain (4) · Belgium (3) · Germany (3) · Switzerland (3) · Austria (2) · Italy (2) · Australia (1) · Belarus (1) · Hungary (1) · Indonesia (1)
Anastasia D. Egorova, MD PhD (1) · Bentong Yu, MD (1) · Bernhard Kuhn, MD (1) · Bing Jia, MD, PhD (1) · Charlotte De Lange, MD PhD (1) · D. Scott Lim, MD (1) · David Morales, MD (1) · Dean B. Andropoulos, M.D. (1) · Denis Schmartz, MD (1) · Edgar Jaeggi, MD (1) · Elisa Llurba, MD, PhD (1) · Emanuela R Valsangiacomo Buechel, Prof. (1) · Eric Horlick, MD (1) · Gabriel Altit (1) · Gerd P Meyer, MD (1)
PMID 23972966, PMID 11060529, PMID 12084585, PMID 15337224, PMID 16765134, PMID 17210844, PMID 17606845, PMID 18242267, PMID 19465439, PMID 19619781, PMID 19808416, PMID 20453699, PMID 20606124, PMID 20620718, PMID 21875911, PMID 22192662, PMID 23067916, PMID 23102686, PMID 23228403, PMID 23239839, PMID 23247302, PMID 23711443, PMID 23790549, PMID 24207068, PMID 24589851, PMID 24644309, PMID 24687311, PMID 26185211, PMID 27214694, PMID 27686343, PMID 27806964, PMID 27837950, PMID 28087606, PMID 28566262, PMID 31506079, PMID 31623840, PMID 34253175, PMID 34265312, PMID 35355435, PMID 37264734, PMID 37435053, PMID 38530688, PMID 38726920, PMID 39040670, PMID 39227910, PMID 40470125, PMID 40689152, PMID 40695536, PMID 40701798, PMID 41491678
5UL1TR002240-05 (1), R01HL039052 (1), R01HL041786 (1), R01HL135061 (1), R01HL155597 (1), R21HD055501 (1), U01HL063411 (1)