41 completed, 6 unknown, 1 active not recruiting, 1 not yet recruiting. 50 Phase 4.
| Phase | Trials | Status |
|---|---|---|
| Phase 4 | 50 | Completed 41, Unknown 6, Active not recruiting 1, Not yet recruiting 1, Terminated 1 |
Follow Chronic Periodontitis: new trials by email Literature Review of Chronic Periodontitis trials Research Report on Chronic Periodontitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Clinical and Radiographic Evaluation of Doxycycline and Atorvastatin Loaded Chitosan Nanoparticles as an Adjunctive to Scaling and Root Planning in the Management of Chronic Periodontitis. A Randomized Controlled Clinical Trial. Doxycycline and Atorvastatin loaded Chitosan nanoparticles local drug - Chronic Periodontitis | Phase 4 | Not yet recruiting | Fayoum University | 80 | 2026-06-01 | 2026-06-08 |
| Clinical Efficacy of 1% Metformin and Alendronate Gel in Adjunct to Fibrin in Chronic Periodontitis Platelet rich fibrin, Metformin hydrochloride powder, alendronate sodium powder - Alveolar Bone Loss Associated Chronic Periodontitis | Phase 4 | Active not recruiting | Bahria University | 120 | 2025-01-22 | 2025-03-04 |
| Advanced Platelet-rich Fibrin Combined With Open Debridement in Management of Suprabony Periodontal Defects advanced PRF - Periodontitis, Adult | Phase 4 | Completed | October University for Modern Sciences and Arts | 30 | 2021-11-21 | 2023-03-27 |
| Regenerative Potential of Advanced Platelet Rich Fibrin and Bioactive Glass (Perioglas®). open flap debridement and filled with A-PRF ( Advanced platelet rich fibrin), open flap debridement and filled with Bioactive glass (Perioglas®), open flap debridement and filled Bioactive glass (Perioglas®) and A-PRF - Chronic Periodontitis, Bone Loss | Phase 4 | Completed | Maharishi Markendeswar University (Deemed to be University) | 48 | 2020-12-01 | 2022-11-08 |
| Evaluation Efficacy of Melatonin Gel as Adjunctive Therapy in Chronic Periodontitis Melatonin2%gel, PLACEBO - Chronic Periodontitis | Phase 4 | Completed | Al-Azhar University | 40 | 2020-04-01 | 2023-03-10 |
| Comparison of Clinical and Radiographic Parameters in the Application of Cross-linked Hyaluronic Acid 1.8% and Enamel Matrix Derivative in Periodontal Regeneration. Cross-Linked Hyaluronate Gel Prefilled Syringe 30 MG/3ML, Enamel Matrix Proteins (Active comparator group) - Chronic Periodontitis, Periodontal Bone Loss | Phase 4 | Completed | Andres Lopez Roldan | 53 | 2020-03-01 | 2026-08-03 |
| Treatment of Periodontitis in Menopausal Patients Polyunsaturated Fatty Acids, olive oil - Menopausal Patients, Chronic Periodontitis | Phase 4 | Completed | Hadir F. El-Dessouky | 20 | 2020-01-22 | 2024-02-12 |
| Hyaluronic Acid 0.2% Application Enhanced Chronic Periodontitis Treatment in Non-surgical Phase 0.2% hyaluronic acid gel - Chronic Periodontitis, Hyaluronic Acid | Phase 4 | Completed | University of Medicine and Pharmacy at Ho Chi Minh City | 28 | 2019-06-21 | 2020-12-19 |
| Use of the xCELLigence System for Quantification of Bacterial Biofilm's Real Time Formation and Antibiotics Selection. SCALE AND ROOT PLANING, ADJUNTIVE ANTIBIOTICS, MICROBIAL SAMPLING - Chronic Periodontitis, Periodontal Bone Loss | Phase 4 | Completed | University of Valencia | 64 | 2019-02-08 | 2026-05-12 |
| Complex Phytoadaptogenes in Chronic Periodontitis Treatment. Cocktail from complex phytoadaptogens (CFA), Standard non-surgical periodontal treatment (NSPT) - Chronic Periodontitis | Phase 4 | Completed | Vladikavkaz Scientific Center of the Russian Academy of Sciences | 30 | 2019-02-01 | 2020-11-10 |
| Locally Delivered Minocycline in Advanced Periodontitis Minocycline Hydrochloride - Periodontitis, Adult | Phase 4 | Completed | Mahsa University | 40 | 2018-06-25 | 2021-09-23 |
| Porous Metronidazole Loaded Matrix for Local Treatment of Periodontitis. Metronidazole - Chronic Periodontitis | Phase 4 | Unknown | Wroclaw Medical University | 40 | 2018-04-23 | 2019-01-04 |
| Evaluation of Antimicrobial Photodynamic Therapy in Multiple Applications as a Coadjuvant in the Surgical Therapy of Access to Scaling Photodynamic Therapy, scaling and root planing - Chronic Periodontitis | Phase 4 | Completed | University of Sao Paulo | 20 | 2018-04-07 | 2018-04-13 |
| Adjunctive Hydrogen Peroxide for Periodontal Therapy Hydrogen Peroxide Gel, 13 weeks, Hydrogen Peroxide Gel, 26 weeks, Scaling and Root planing group - Periodontitis, Chronic | Phase 4 | Terminated | Loma Linda University | 42 | 2018-04-02 | 2022-12-21 |
| Melatonin as an Adjunctive Therapy for Chronic Periodontitis. Melatonin, Placebo - Periodontal Diseases | Phase 4 | Completed | Mansoura University | 74 | 2016-07-04 | 2017-12-11 |
| Effect of Probiotic Lozenges on Halitosis in Patients With Chronic Periodontitis L. reuteri Prodentis® lozenges, Placebo lozenges - Halitosis | Phase 4 | Unknown | University of Zagreb | 30 | 2016-06-01 | 2016-06-03 |
| "Efficacy Of 1.2% Rosuvastatin Gel In The Management Of Infrabony Defects" Rosuvastatin - Adult Periodontitis | Phase 4 | Completed | Dr. D. Y. Patil Dental College & Hospital | 10 | 2016-01-28 | 2018-09-19 |
| Simvastatin Gel With Perforated Resorbable Membranes in Treatment of Intrabony Defects in Chronic Periodontitis Simvastatin, EDTA, Occlusive membrane - Chronic Periodontitis | Phase 4 | Completed | Ain Shams University | 40 | 2016-01-01 | 2018-02-06 |
| The Effects of Periodontal Therapy on Glycemic Control in Diabetic Patients amoxicillin 500mg and metronidazole 400mg - Chronic Periodontitis, Generalized | Phase 4 | Completed | Taibah University | 44 | 2015-06-01 | 2019-10-21 |
| Effect of Arthrospira Platensis (Spirulina) as an Adjunct to Scaling and Root Planing on Salivary Antioxidant Levels in Chronic Periodontitis Subjects Spirulina capsules - Chronic Periodontitis | Phase 4 | Completed | Tatyasaheb Kore Dental College | 70 | 2015-05-01 | 2016-09-01 |
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Periodontitis (15) · Periodontal Diseases (5) · Alveolar Bone Loss (3) · Diabetes Mellitus (3) · Bone Diseases, Metabolic (1) · Dental Plaque (1) · Dysbiosis (1) · Halitosis (1) · Inflammation (1) · Osteopetrosis, mild autosomal recessive form (1) · Osteoporosis (1) · Periodontal Attachment Loss (1) · Periodontal Pocket (1) · Renal Insufficiency, Chronic (1)
Chronic Disease (50) · Disease Attributes (50) · Mouth Diseases (50) · Pathologic Processes (50) · Pathological Conditions, Signs and Symptoms (50) · Stomatognathic Diseases (50) · Periodontal Diseases (45) · Periodontitis (35) · Bone Diseases (5) · Metabolic Diseases (5) · Musculoskeletal Diseases (5) · Nutritional and Metabolic Diseases (5) · Periodontal Atrophy (4) · Bone Resorption (3) · Endocrine System Diseases (3)
Root Planing (10) · Tooth Exfoliation (10) · Amoxicillin (5) · Metronidazole (5) · Minocycline (3) · Photochemotherapy (3) · Fatty Acids, Omega-3 (2) · Moxifloxacin (2) · Starch (2) · Albendazole (1) · Atorvastatin (1) · Bioglass (1) · Chlorhexidine (1) · Ciprofloxacin (1) · Doxycycline (1)
Tatyasaheb Kore Dental College (6) · University of Guarulhos (3) · University of Sao Paulo (3) · Dr. D. Y. Patil Dental College & Hospital (2) · Ondine Research Laboratories (2) · Ain Shams University (1) · Al-Azhar University (1) · Andres Lopez Roldan (1) · Bahria University (1) · Facultad Nacional de Salud Publica (1) · Fayoum University (1) · Federal University of Maranhao (1) · Francisco Alpiste Illueca (1) · Hadir F. El-Dessouky (1) · Haner Direskeneli, Prof (1)
India (6) · Brazil (5) · Egypt (5) · Spain (3) · Canada (2) · United States (2) · Belgium (1) · Chile (1) · Colombia (1) · Croatia (1) · Germany (1) · Malaysia (1) · Pakistan (1) · Poland (1) · Russia (1)
Girish D Deore, BDS (2) · Ahmed Y Gamal, Professor (1) · Alpiste Illueca Francisco, Professor (1) · Andrea Mombelli, Dr.med.dent. (1) · Archana Singh, MDS (1) · Bahar Kuru, Prof. Dr. (1) · Carlos M Ardila, DDS Cand PhD (1) · Cary Galler, DDS (1) · Edward Putnins, DDS (1) · Enilson A Sallum, PhD (1) · Etika Rathi, MDS (1)
PMID 33197289, PMID 14742657, PMID 16018754, PMID 17355365, PMID 20151809, PMID 20383102, PMID 21261673, PMID 22326720, PMID 23327689, PMID 24452825, PMID 25808980, PMID 26604272, PMID 28303587, PMID 28498507, PMID 31197657, PMID 33382101, PMID 35062940, PMID 37355276, PMID 38510979, PMID 40106008