51 completed, 9 unknown, 1 recruiting. 61 Phase 2, 25 Phase 3, 10 Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Phase 2 | 61 | Completed 51, Unknown 9, Recruiting 1 |
| Phase 3 | 25 | Completed 24, Unknown 1 |
| Phase 1 | 10 | Completed 8, Unknown 2 |
Follow Chronic Periodontitis: new trials by email Literature Review of Chronic Periodontitis trials Research Report on Chronic Periodontitis
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| 3-Month Clinical Trial of Liquid S-PRF in Periodontal Debridement for Periodontitis Stages II-IV Normal saline irrigation, Platelet rich fibrin - Periodontitis Stage II, Periodontitis Stage III | Phase 2 | Recruiting | Mahsa University | 14 | 2024-04-01 | 2025-12-19 |
| Effect of Frankincense Extract Gel on Non-Surgical Treatment of Chronic Periodontitis scaling and root planing, Frankincense extract gel natural herbal product - Chronic Periodontitis | Phase 2 | Unknown | Tanta University | 20 | 2021-04-01 | 2021-08-16 |
| Beta-Tricalcium Phosphate and Concentrated Growth Factors in Treatment of Intra-bony Defect Randomized Clinical Trial open flap debridement, use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate plus concentrated growth factors, use of Biodegradable Gelatin Sponge loaded with Beta-tricalcium Phosphate alone - Chronic Periodontitis, Intrabony Periodontal Defect | Phase 2 | Completed | Tanta University | 40 | 2021-01-01 | 2021-10-04 |
| CBD Effects on Periodontal Health of Patients With Chronic Periodontitis placebo dental gel, placebo toothpaste, Cannabidiol dental gel, Cannabidiol toothpaste, Placebo toothpaste, Corsodyl dental gel - Chronic Periodontitis | Phase 1 / Phase 2 | Completed | Palacky University | 90 | 2020-11-05 | 2022-08-11 |
| Treatment of Chronic Medium-severe Periodontitis With Mesenchymal Stem Cells Predifferentiated in Osteogenic Direction mesenchymal stem cells, standard treatment - Periodontitis, Chronic | Phase 1 / Phase 2 | Completed | Institute of Biophysics and Cell Engineering of National Academy of Sciences of Belarus | 10 | 2020-08-03 | 2021-02-09 |
| A Study to Evaluate the Efficacy and Safety of ALH-L1005 in Patients With Chronic Periodontitis ALH-L1005 600mg/day, ALH-L1005 1,200mg/day, Placebo - Chronic Periodontitis | Phase 2 | Completed | AngioLab, Inc. | 117 | 2020-07-16 | 2022-08-11 |
| Antimicrobial Photodynamic Therapy in Chronic Periodontitis and Diabetes Mellitus Indocyanine green - Type 2 Diabetes Mellitus, Prediabetic State | Phase 2 / Phase 3 | Completed | King Saud University | 80 | 2020-06-01 | 2021-04-23 |
| New Periodontitis Treatment Based on Hyaluronic Acid and Melatonin Tetracycline-Metronidazole (TM) group, TM-Melatonin-Hyaluronic acid (TM-MHa) group - Chronic Periodontitis | Phase 2 | Completed | Concordia Dent Srl | 50 | 2019-01-15 | 2020-01-27 |
| Efficacy of Proanthocyanidins in Non-Surgical Periodontal Therapy Minimally invasive non-surgical therapy, Subgingival application of collagen hydrogels with proanthocyanidins, Collection of saliva samples - Periodontitis, Adult | Phase 2 | Completed | Lithuanian University of Health Sciences | 46 | 2019-01-09 | 2022-06-30 |
| Transplantation of Bone Marrow Mesenchymal Stromal Cells for Periodontal Regeneration Transplantation of allogeneic MSCs in periodontal disease - Chronic Periodontal Disease, Aggressive Periodontitis | Phase 1 / Phase 2 | Unknown | Instituto Venezolano de Investigaciones Cientificas | 30 | 2018-08-30 | 2023-08-04 |
| Teh Effect of Subgingival Irrigation Wif Ketorolac and Chlorhexidine in Patients Wif Chronic Periodontist Ketorolac, Chlorhexidine 2% - Chronic Periodontitis | Phase 2 / Phase 3 | Completed | Amirhossein Farahmand | 2 | 2018-04-10 | 2019-07-05 |
| Minimally Invasive Flap With Platelet Rich Fibrin or Growth Factor Enhanced Matrix in Treatment of Intrabony Defect Minimal invasive flap technique, Minimally invasive flap with root conditioning (EDTA) and platelet rich fibrin, minimally invasive flap with root contioning by EDTA and growth factor enhanced matrix GEM21S - Periodontal Regeneration | Phase 2 | Completed | Tanta University | 21 | 2018-01-01 | 2021-06-18 |
| Glycemic Control in T2DM Through Non-Surgical Periodontal Therapy Metronidazole, Scaling Root Planing, Oral Hygiene Instructions - Chronic Periodontitis, Type 2 Diabetes Mellitus | Phase 2 / Phase 3 | Completed | Dow University of Health Sciences | 150 | 2018-01-01 | 2020-08-21 |
| Effect of Ashwagandha on Salivary Antioxidant and Serum c Reactive Protein in Chronic Generalized Periodontitis Ashwagandha, Placebo - Chronic Periodontitis | Phase 1 / Phase 2 | Completed | Tatyasaheb Kore Dental College | 50 | 2017-11-30 | 2018-05-23 |
| Effect Of A Locally Delivered Probiotic Sacchraomyces Boulardii In The Management Of Chronic Periodontitis Saccharomyces Boulardii 250 MG - Chronic Periodontitis | Phase 1 / Phase 2 | Completed | Tatyasaheb Kore Dental College | 31 | 2017-11-20 | 2018-05-11 |
| Amoxicillin to Prevent Bacteria and Inflammatory Biomarkers After Intensive Periodontal Therapy Amoxicillin, Placebo - Chronic Periodontitis, Bacteremia | Phase 2 | Unknown | Universidad El Bosque, Bogotá | 90 | 2017-09-21 | 2017-11-27 |
| Comparison of Salivary Interleukin-1β and Matrix Metalloproteinase-8 Levels in Individuals With Chronic Periodontitis Nigella Sativa Oil, Normal saline - Chronic Periodontitis | Phase 2 | Unknown | University of Health Sciences Lahore | 25 | 2017-09-11 | 2017-09-01 |
| To Compare Efficacy of Low Dose Diclofenac (25mg) in Management of Postoperative Pain After Periodontal Flap Surgery low dose diclofenac - Chronic Periodontitis | Phase 1 / Phase 2 | Completed | Tatyasaheb Kore Dental College | 20 | 2016-03-20 | 2018-05-14 |
| Local Host Modulating Agents Alendronate & Aloe Vera for Treatment of Furcation Defects in Chronic Periodontitis placebo, Alendronate, Aloe Vera - Chronic Periodontitis | Phase 2 / Phase 3 | Completed | Government Dental College and Research Institute, Bangalore | 90 | 2016-03-01 | 2017-06-29 |
| Locally Delivered Metformin & Rosuvastatin for Treatment of Intrabony Defects in Chronic Periodontitis Placebos, Rosuvastatin, Metformin - Chronic Periodontitis | Phase 2 / Phase 3 | Completed | Government Dental College and Research Institute, Bangalore | 90 | 2016-02-10 | 2017-06-29 |
Showing 20 of 61. Sign in to see all of them.
Periodontitis (7) · Periodontal Diseases (4) · Diabetes Mellitus, Type 2 (3) · Aggressive Periodontitis (1) · Alveolar Bone Loss (1) · Bacteremia (1) · Inflammation (1) · Prediabetic State (1)
Chronic Disease (61) · Disease Attributes (61) · Mouth Diseases (61) · Pathologic Processes (61) · Pathological Conditions, Signs and Symptoms (61) · Stomatognathic Diseases (61) · Periodontal Diseases (57) · Periodontitis (54) · Diabetes Mellitus (3) · Endocrine System Diseases (3) · Glucose Metabolism Disorders (3) · Metabolic Diseases (3) · Nutritional and Metabolic Diseases (3) · Bacterial Infections (1) · Bacterial Infections and Mycoses (1)
Tooth Exfoliation (6) · Root Planing (5) · Atorvastatin (4) · Metformin (4) · Rosuvastatin Calcium (4) · Alendronate (3) · Azithromycin (2) · Dimethyl Sulfoxide (2) · Doxycycline (2) · Metronidazole (2) · Prolactin-Releasing Hormone (2) · Amoxicillin (1) · Ashwagandha (1) · Capsules (1) · Diclofenac (1)
Government Dental College and Research Institute, Bangalore (21) · Tanta University (3) · Tatyasaheb Kore Dental College (3) · Islamic Azad University, Sanandaj (2) · October 6 University (2) · SVS Institute of Dental Sciences (2) · University of Campinas, Brazil (2) · Yuhan Corporation (2) · Air Force Military Medical University, China (1) · Amirhossein Farahmand (1) · AngioLab, Inc. (1) · Aristotle University Of Thessaloniki (1) · Ataturk University (1) · Concordia Dent Srl (1) · Dow University of Health Sciences (1)
India (13) · Egypt (4) · Brazil (3) · Chile (3) · Iran (3) · South Korea (3) · Pakistan (2) · Saudi Arabia (2) · Belarus (1) · China (1) · Colombia (1) · Czechia (1) · Greece (1) · Japan (1) · Lithuania (1)
A R Pradeep, MDS (2) · Dilip Khambete, MDS (2) · Rampalli V Chandra, MDS;DNB (2) · Ahmed Y Gamal, PhD (1) · Antonis Konstantinidis, Professor (1) · Avani Pradeep, MDS (1) · Avani R Pradeep, MDS (1) · Bruno CV Gurgel, Doctor (1) · Cristiane C Bergamaschi, PhD (1) · David R Rosenberg, DDS, MDS (1) · Dr. Anuj Sharma, BDS, MDS (1) · Enas A Elgendy, MD (1) · Enas Elgendy, ph.D (1)
PMID 27715376, PMID 30624092, PMID 31102044, PMID 32794485, PMID 33197289, PMID 33413320, PMID 33899259, PMID 34087466, PMID 38847929