36 completed, 14 unknown, 8 recruiting, 2 terminated. 26 Not applicable, 3 Phase 4, 1 Early Phase 1.
| Phase | Trials | Status |
|---|---|---|
| Not applicable | 26 | Completed 16, Unknown 5, Recruiting 3, Not yet recruiting 1, Terminated 1 |
| Phase 4 | 3 | Completed 2, Unknown 1 |
| Early Phase 1 | 1 | Completed 1 |
Follow Central Sensitisation: new trials by email Literature Review of Central Sensitisation trials Research Report on Central Sensitisation
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Sedentary Status and Multidimensional Outcomes in Fibromyalgia Assessment Only - Fibromyalgia, Sedentary Behavior | Not applicable | Not yet recruiting | Izmir Democracy University | 66 | 2026-05-15 | 2026-02-06 |
| Comparison of Pain, Sensitisation, Function and Quality of Life According to Stenosis Degree in Chronic Neck Pain Pain, central sensitization,functional status and quality of life. - Central Sensitisation, Cervical Spine Stenosis | Not applicable | Completed | Izmir Democracy University | 88 | 2025-12-15 | 2026-11-04 |
| The Effect of Griffonia Simplicifolia on Pain Intensity, Central and Peripheral Sensitization, Painmodulation in Healthy Volunteers Griffonia simplicifolia, Placebo - Chronic Pain, Central Sensitisation | Not applicable | Recruiting | Medical University of Graz | 20 | 2025-09-12 | 2025-06-17 |
| Effect of Boswellia Serrata on Pain Intensity, Central and Peripheral Sensitization, and Pain Modulation in Healthy Volunteers Boswellia serrata extract, Placebo - Chronic Pain, Central Sensitisation | Not applicable | Recruiting | Medical University of Graz | 12 | 2025-09-01 | 2025-09-24 |
| Relationship Between Central Sensitization Levels and Treatment Outcomes in Frozen Shoulder Treatment Treatment outcome - Frozen Shoulder, Central Sensitisation | Completed | Sultan 1. Murat State Hospital | 87 | 2025-08-09 | 2025-12-31 | |
| Symptom Distribution and Pain Sensitization in Carpal Tunnel Syndrome Nerve ultrasound, Nerve conduction studies, Pressure pain threshold - Carpal Tunnel Syndrome, Central Sensitisation | Recruiting | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 80 | 2025-06-21 | 2025-08-11 | |
| Investigation of the Relationship Between Central Sensitization and Balance in Fibromyalgia Biodex Balance System, Pressure Pain Threshold (PPT) Measurement with Algometer, Conditioned Pain Modulation (CPM) - Fibromyalgia Syndrome, Central Sensitisation | Recruiting | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 75 | 2025-02-18 | 2025-09-12 | |
| Investigation of Central Sensitization and Associated Factors in Patients With Lipedema Pain-Pressure Threshold Measurement With an Algometer, Central Sensitization Inventory, Numeric Rating Scale - Lipedema, Central Sensitisation | Recruiting | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 50 | 2024-12-06 | 2025-09-08 | |
| Myofascial Release Technique in Women With Primary Dysmenorrhea Myofascial Release, Sham-Myofascial Release - Dysmenorrhea Primary, Central Sensitisation | Not applicable | Recruiting | Gazi University | 36 | 2024-09-10 | 2024-11-21 |
| Effect of Pregabalin on Shoulder Pain in Patients With Central Sensitization After Arthroscopic Rotator Cuff Repair Pregabalin - Rotator Cuff Tears, Central Sensitisation | Phase 4 | Unknown | The Catholic University of Korea | 76 | 2024-09-01 | 2024-08-23 |
| Evaluation of the Effect of Central Sensitivity on Pain and Functional Status After Total Knee Joint Replacement Surgery Total knee arthroplasty - Central Sensitisation, Postoperative Pain | Unknown | Istanbul University | 80 | 2024-08-12 | 2024-08-15 | |
| Investigating the Association Between Central Sensitization and Breathing Pattern Disorders Central Sensitisation | Unknown | Sahmyook University | 40 | 2024-07-03 | 2024-07-03 | |
| Clinical Trial on Deprescribing Associated With a Psychoeducational Program Using Virtual Reality for Patients With Chronic Pain and Central Sensitization REDOCVR Psychoeducational Program, Standard Educational Materials - Chronic Pain, Central Sensitisation | Not applicable | Completed | Badalona Serveis Assistencials | 174 | 2024-05-06 | 2026-05-28 |
| Investigation of the Relationship Between Central Sensitization and Neuropathic Pain in Lumbar Disc Herniation Central sensitization inventory, Short form-36, Oswestry Low Back Pain Disability Questionnaire - Central Sensitisation | Unknown | Marmara University | 180 | 2024-01-16 | 2024-02-21 | |
| Investigation of the Relationship Between Pain Sensitization and Diagnostic Parameters in Carpal Tunnel Syndrome Nerve ultrasound, Nerve conduction studies, Pressure pain threshold - Central Sensitisation, Carpal Tunnel Syndrome | Completed | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 60 | 2023-10-01 | 2025-09-12 | |
| Brain MRI for Knee OA Cold Pressor Gel Test - Chronic Pain, Central Sensitisation | Not applicable | Unknown | Toronto Rehabilitation Institute | 66 | 2023-09-01 | 2023-08-18 |
| Pain Phenotypes in Patients With Fibromyalgia Syndrome Pain classification method - Fibromyalgia, Primary, Fibromyalgia | Completed | Kutahya Health Sciences University | 65 | 2023-07-10 | 2026-03-30 | |
| Investigation of the Effect of Central Sensitization (CS) on Steroid Injection Response in Rotator Cuff Lesion Injection of 1 CC Betamethasone Dipropionate + Betamethasone Sodium Phosphate (Diprospan) and 4 cc 2% Prilocaine (Priloc)mixture into the subacromial space - Central Sensitisation, Subacromial Impingement Syndrome | Not applicable | Completed | Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey | 44 | 2023-06-02 | 2025-09-12 |
| Nociplastic Pain Symptoms and Sensory Profiles in Low Back Pain Central Sensitisation, Low Back Pain | Active not recruiting | Vrije Universiteit Brussel | 103 | 2023-06-01 | 2025-04-01 | |
| Pain Processing In Relation To Breathing Paced Resonance Frequency Breathing, Paced Breathing at Natural Frequency, Heat Stimulations - Central Sensitisation, Pain | Not applicable | Unknown | Balgrist University Hospital | 200 | 2023-05-14 | 2023-12-14 |
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Chronic Pain (18) · Fibromyalgia (11) · Pain (7) · Neuralgia (6) · Low Back Pain (5) · Hyperalgesia (4) · Shoulder Pain (4) · Headache (3) · Kinesiophobia (3) · Nociplastic Pain (3) · Osteoarthritis, Knee (3) · Pain, Postoperative (3) · Arthritis (2) · Axial Spondyloarthritis (2) · Carpal Tunnel Syndrome (2)
Pathological Conditions, Signs and Symptoms (43) · Neurologic Manifestations (42) · Signs and Symptoms (42) · Pain (34) · Musculoskeletal Diseases (25) · Nervous System Diseases (24) · Neuromuscular Diseases (18) · Rheumatic Diseases (15) · Joint Diseases (13) · Muscular Diseases (13) · Peripheral Nervous System Diseases (9) · Mental Disorders (8) · Arthritis (6) · Pathologic Processes (5) · Wounds and Injuries (5)
Postsynaptic Potential Summation (4) · Central Nervous System Sensitization (3) · Quality of Life (3) · 4-amino-4'-hydroxylaminodiphenylsulfone (2) · Capsaicin (2) · Duloxetine Hydrochloride (2) · Exercise (2) · Nerve Conduction Studies (2) · Pregabalin (2) · Surveys and Questionnaires (2) · Amitriptyline (1) · Arthroplasty, Replacement, Knee (1) · Cognitive Behavioral Therapy (1) · Exercise Therapy (1) · Frankincense (1)
Marmara University (9) · Sultan Abdulhamid Han Training and Research Hospital, Istanbul, Turkey (6) · University Ghent (4) · Cukurova University (3) · Medical University of Graz (3) · Toronto Rehabilitation Institute (3) · Balgrist University Hospital (2) · Istanbul University - Cerrahpasa (2) · Izmir Democracy University (2) · University of Cape Town (2) · Vrije Universiteit Brussel (2) · BC Women's Hospital & Health Centre (1) · Badalona Serveis Assistencials (1) · Bursa Yuksek Ihtisas Training and Research Hospital (1) · Dokuz Eylul University (1)
Turkey (Türkiye) (28) · Belgium (6) · Spain (5) · Canada (4) · Austria (3) · South Africa (2) · Switzerland (2) · United States (2) · Denmark (1) · Egypt (1) · Greece (1) · India (1) · Italy (1) · Netherlands (1) · Singapore (1)
Aldo Scafoglieri, PhD (2) · Emre Ata, Asst.Prof (2) · Victoria J Madden, PhD (2) · Beyza Yazgan Dagli (1) · Canan Sanal- Toprak, Asst.Prof (1) · Dinesh Kumbahre, PhD (1) · Dinesh Kumbhare, MD, PhD (1) · Dinesh M Kumbahre, MD,PhD (1) · Eleni V Kapreli, MSc,PhD (1)
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2023 (1), K43TW011442 (1)