12 completed, 7 unknown, 6 terminated, 2 not yet recruiting. 7 Not applicable, 5 Phase 2, 2 Early Phase 1, 2 Phase 1, 1 Phase 4.
Follow Cavernous Sinus Syndromes: new trials by email Literature Review of Cavernous Sinus Syndromes trials Research Report on Cavernous Sinus Syndromes
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Biological Collection of the Rare Diseases of the Brain and Eye Vessels Cohort - 2 Biocollection, Neurological evaluation and Biocollection - CADASIL, Cavernous Angioma | Not applicable | Not yet recruiting | Assistance Publique - Hôpitaux de Paris | 600 | 2026-06-30 | 2026-06-16 |
| Daratumumab for Familial Cerebral Cavernous Malformations: A Single-Arm Safety and Efficacy Study Daratumumab - Cavernous Malformation, Cerebral | Early Phase 1 | Not yet recruiting | Beijing Tiantan Hospital | 10 | 2025-07-01 | 2025-06-18 |
| Endovascular Management of Direct Carotid-cavernous Fistula Endovascular management of direct carotid-cavernous fistula - Carotid-Cavernous Sinus Fistula | Not applicable | Unknown | Sohag University | 1 | 2023-11-01 | 2023-11-14 |
| Functional Magnetic Resonance Imaging (fMRI) Vascular Reactivity in Cerebral Cavernous Malformations (CCM) Hyperventilation and CO2 challenge - Cerebral Cavernous Malformation | Not applicable | Terminated | University of New Mexico | 5 | 2023-06-15 | 2025-06-11 |
| Role of 18F-FDG PET/CT in the Evaluation of Cavernous Sinus Syndrome: a Pilot Study FDG radiotracer - Cavernous Sinus Syndrome, Cavernous Sinus Meningioma | Completed | Post Graduate Institute of Medical Education and Research, Chandigarh | 54 | 2022-07-01 | 2024-12-06 | |
| The Symptomatic Cerebral Cavernous Malformation Trial of REC-994 REC-994, Placebo - Cerebral Cavernous Malformation | Phase 2 | Completed | Recursion Pharmaceuticals Inc. | 62 | 2022-03-17 | 2026-10-22 |
| Cerebral Blood Flow Evaluation With Trancranial Doppler After Interscalene Nerve Block TCD Measurement - Regional Anesthesia, Horner Syndrome | Terminated | Stanford University | 10 | 2021-03-04 | 2021-09-16 | |
| CCM Blood Biomarker Validation Study CCM Hemorrhagic Panel - Hemorrhagic Stroke, Intracerebral, Cerebral Cavernous Malformation | Terminated | Texas Tech University Health Sciences Center, El Paso | 12 | 2021-01-01 | 2023-09-01 | |
| Safety and Feasibility of the Infinity Catheter for Radial Access Transradial approach - Brain Tumor, Stroke, Acute | Completed | Rutgers, The State University of New Jersey | 80 | 2020-10-01 | 2023-12-11 | |
| Study on Treatment Decision-Making and Prognostic Follow-Up for Untreated Cerebral Cavernous Malformations Hemangioma, Cavernous, Central Nervous System | Recruiting | Beijing Tiantan Hospital | 1200 | 2020-09-01 | 2025-07-30 | |
| Biomarkers of CASH observational - Cerebral Cavernous Malformation, Cavernous Angioma | Active not recruiting | University of Chicago | 1040 | 2020-05-22 | 2025-08-11 | |
| Quantitative Susceptibility Biomarker and Brain Structural Property for Cerebral Cavernous Malformation Related Epilepsy Cavernous Malformation, Cerebral, Cavernous Angioma | Recruiting | yuanli Zhao | 200 | 2019-09-03 | 2019-09-04 | |
| Exploration of Pupil Dilation in Horner's Patients Taking Flomax 10% phenylephrine - Horner Syndrome | Phase 4 | Terminated | Denver Health and Hospital Authority | 1 | 2018-09-21 | 2022-03-03 |
| CASH (Cavernous Angiomas With Symptomatic Hemorrhage) Trial Readiness CCM, Cavernoma | Completed | University of Chicago | 123 | 2018-08-20 | 2024-06-27 | |
| Atorvastatin Treatment of Cavernous Angiomas With Symptomatic Hemorrhage Exploratory Proof of Concept (AT CASH EPOC) Trial Atorvastatin, Placebo - Cerebral Cavernous Malformation | Phase 1 / Phase 2 | Completed | University of Chicago | 80 | 2018-07-17 | 2025-08-22 |
| The Effects of Horner's Syndrome Developing After Interscalene Brachial Plexus Block on Autonomic Nervous Activity Interscalene brachial plexus block, 0.75% ropivacaine - Brachial Plexus Block, Horner Syndrome | Completed | Daegu Catholic University Medical Center | 48 | 2018-06-18 | 2021-06-18 | |
| Treat_CCM: Propranolol in Familial Cerebral Cavernous Malformation Propranolol - Cerebral Cavernous Malformation | Phase 2 | Completed | Mario Negri Institute for Pharmacological Research | 71 | 2018-04-11 | 2022-02-25 |
| Effect of Oral Propranolol on mRNA Expresssion in Symptomatic Cavernous Malformation Propranolol, DNA and RNA Analysis - Cerebral Cavernous Malformations | Phase 2 | Terminated | St. Joseph's Hospital and Medical Center, Phoenix | 4 | 2018-01-24 | 2024-04-19 |
| Treatments and Outcomes of Untreated Cerebral Cavernous Malformations in CHina. Surgery, Observation - Cerebral Cavernous Malformations | Unknown | First Affiliated Hospital of Fujian Medical University | 2000 | 2018-01-01 | 2018-03-19 | |
| Pupillometry in Horner's Syndrome Automated pupillometry - Horner's Syndrome, Stroke | Not applicable | Unknown | University of Zurich | 135 | 2017-02-15 | 2021-01-11 |
Showing 20 of 30. Sign in to see all of them.
Hemangioma, Cavernous, Central Nervous System (15) · Hemangioma, Cavernous (7) · Horner Syndrome (6) · Intracranial Aneurysm (4) · Carotid-Cavernous Sinus Fistula (3) · Hemangioma (2) · Hemangioma, Capillary (2) · Stroke (2) · Arteriovenous Malformations (1) · Brain Neoplasms (1) · CADASIL (1) · Carotid Stenosis (1) · Cavernous Sinus Thrombosis (1) · Central Nervous System Vascular Malformations (1)
Brain Diseases (30) · Central Nervous System Diseases (30) · Nervous System Diseases (30) · Cardiovascular Diseases (24) · Vascular Diseases (24) · Cardiovascular Abnormalities (21) · Congenital Abnormalities (21) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (21) · Vascular Malformations (21) · Neoplasms (20) · Hematologic Diseases (19) · Hemic and Lymphatic Diseases (19) · Hemorrhagic Disorders (19) · Hemostatic Disorders (19)
Propranolol (2) · Ropivacaine (2) · Atorvastatin (1) · DNA (1) · Doxycycline (1) · Fentanyl (1) · Gels (1) · Mastectomy (1) · Observation (1) · Phenylephrine (1) · Propofol (1) · Simvastatin (1) · Surgical Procedures, Operative (1) · Timolol (1) · Watchful Waiting (1)
University of Chicago (3) · Beijing Tiantan Hospital (2) · Daegu Catholic University Medical Center (2) · University of California, San Francisco (2) · University of New Mexico (2) · Assistance Publique - Hôpitaux de Paris (1) · Denver Health and Hospital Authority (1) · First Affiliated Hospital of Fujian Medical University (1) · Mario Negri Institute for Pharmacological Research (1) · Nfocus Neuromedical (1) · Post Graduate Institute of Medical Education and Research, Chandigarh (1) · Rady Children's Hospital, San Diego (1) · Recursion Pharmaceuticals Inc. (1) · Rutgers, The State University of New Jersey (1) · Seoul National University Hospital (1)
United States (14) · China (6) · South Korea (4) · Egypt (1) · Germany (1) · India (1) · Italy (1) · Switzerland (1)
Issam A Awad, MD (2) · Issam Awad, MD (2) · Anna Maria Bombardieri, MD, PhD (1) · Blaine Hart, MD (1) · Chanhung Lee, MD (1) · Cristos Ifantides, MD (1) · Daniel F Hanley, MD (1) · Daniel Hanley, MD (1) · Dezhi Kang, MD,PHD (1) · Elisabetta Dejana, Professor (1) · Helen Kim, MPH, PhD (1) · Helen Kim, PhD (1) · Hongqi Zhang, MD (1) · JeongEun Kim, MD. PhD. (1) · Jong Hae Kim, MD (1)
PMID 19833796, PMID 24323376, PMID 24401931, PMID 25472749, PMID 25556204, PMID 25560203, PMID 25565562, PMID 26795600, PMID 28318403, PMID 28387823, PMID 28489816, PMID 28534135, PMID 30140608, PMID 31643041, PMID 31776290, PMID 31825263, PMID 32100472, PMID 32398113, PMID 32461638, PMID 32467184, PMID 32467778, PMID 32951540, PMID 33122314, PMID 33469662, PMID 34389651, PMID 34479577, PMID 34491620, PMID 36403580, PMID 36695309, PMID 37333396, PMID 38134265, PMID 38134268, PMID 38419711, PMID 40120614, PMID 40175401, PMID 40570636, PMID 40614265, PMID 40899314, PMID 41117517, PMID 41608890
U54NS065705 (2), 2017 (1), R01NS114552 (1), U01NS104157 (1)