31 completed, 9 terminated, 8 recruiting, 6 unknown. 18 Phase 2, 14 Not applicable, 7 Phase 3, 4 Phase 4, 3 Phase 1.
Follow Hemangioma, Capillary: new trials by email Literature Review of Hemangioma, Capillary trials Research Report on Hemangioma, Capillary
Tick up to 5 trials to compare them side by side (eligibility, arms, endpoints, adverse events) in a Literature Matrix.
| Trial | Phase | Status | Sponsor | Enrollment | Start | Updated |
|---|---|---|---|---|---|---|
| Rapamycin Dose-Ranging Efficacy Study in Port Wine Stains Rapamycin cream, Pulsed dyed laser - Port Wine Stains | Phase 2 | Not yet recruiting | AFT Pharmaceuticals, Ltd. | 30 | 2026-11-13 | 2026-10-27 |
| Preoperative Embolization for Highly Vascular Brain Tumors Preoperative Endovascular Embolization - Brain Neoplasms, Meningioma | Not applicable | Not yet recruiting | Assiut University | 55 | 2026-10-01 | 2026-09-17 |
| Maximizing Laser Therapy Success for Port-Wine Birthmarks in Pediatric Patients Pulse Dye laser, Pulse Dye Laser (PDL) pulse width stacking, Pulse Dye Laser (PDL) followed by Nd:YAG (Neodymium-doped Yttrium Aluminum Garnet laser) laser. - Port Wine Stains | Not applicable | Recruiting | University of Texas Southwestern Medical Center | 200 | 2026-07-01 | 2026-06-05 |
| Abrupt Discontinuation Versus Gradual Tapering of Propranolol in Infantile Hemangioma Abrupt Discontinuation of Propranolol, Gradual Tapering of Propranolol - Infantile Hemangioma (IH) | Phase 4 | Not yet recruiting | West China Hospital | 110 | 2026-07-01 | 2026-06-24 |
| Risk Stratification and Treatment Decisions in Infantile Hemangioma With Minimal or Arrested Growth Routine Clinical Assessment and Risk Stratification - Infantile Hemangioma (IH) | Not yet recruiting | West China Hospital | 150 | 2026-06-20 | 2026-07-02 | |
| Screening LUMBAR Syndrome in Infants With Infantile Hemangiomas MRI - LUMBAR Syndrome | Not yet recruiting | West China Hospital | 70 | 2026-06-01 | 2026-06-01 | |
| Efficacy and Safety of Different Initial Doses of Oral Propranolol in the Treatment of Ulcerated Infantile Hemangioma propranolol - Infantile Hemangioma | Phase 2 / Phase 3 | Recruiting | West China Hospital | 32 | 2025-01-01 | 2026-09-21 |
| Oral Propranolol Versus Fractional Carbon Dioxide CO2 Laser Assisted Delivery of Topical Timolol for Treatment of Infantile Hemangioma Propranolol 1, Fractional CO2 laser with topical timolol - Infantile Hemangioma (IH) | Not applicable | Completed | Cairo University | 30 | 2025-01-01 | 2026-05-01 |
| Exploration and Evaluation of Amygdalo-Hippocampectomy According to Prof. Coubes' Technique: An Anatomical, Clinical, and Educational Approach Amygdalo-Hippocampectomy - Hippocampal Sclerosis, Dysembryoplastic Neuroepithelial Tumor | Recruiting | University Hospital, Montpellier | 3504 | 2024-08-31 | 2025-04-08 | |
| Agnostic Therapy in Rare Solid Tumors Nivolumab - Urachal Cancer, Parathyroid Carcinoma | Phase 2 | Active not recruiting | Instituto do Cancer do Estado de São Paulo | 28 | 2024-07-16 | 2026-10-13 |
| Enhanced Efficacy Through Optimization of Hemoporfin-Photodynamic Therapy Parameters in Port-Wine Stains irradiation at 84 mW/cm² for 17 minutes per spot, irradiation at 75 mW/cm² for 19 minutes per spot - Port Wine Stains | Not applicable | Completed | Second Affiliated Hospital of Xi'an Jiaotong University | 33 | 2024-07-01 | 2026-01-20 |
| Low-Dose Propranolol and Bleomycin for Infantile Hemangioma (IH) Propranolol + Bleomycin, Propranolol - Infantile Hemangioma (IH) | Not applicable | Completed | Wuhan Integrated Traditional Chinese and Western Medicine Hospital | 260 | 2024-01-01 | 2025-08-05 |
| Real-World Effectiveness and Pharmacogenetics of Belzutifan in VHL Syndrome: The BELIEVE-VHL Trial Belzutifan - Von Hippel Lindau, Von Hippel Lindau Disease | Phase 2 | Recruiting | José Claudio Casali da Rocha | 100 | 2024-01-01 | 2025-09-11 |
| Observational Study for Assessing Treatment and Outcome of Patients With Primary Brain Tumours Using cIMPACT-NOW and 2021 WHO Classification Observational - Glioma, Glioneuronal Tumor | Recruiting | European Organisation for Research and Treatment of Cancer - EORTC | 1650 | 2023-03-21 | 2025-12-17 | |
| Propranolol and Von Hippel-Lindau Disease Propranolol, follow-up - Hemangioblastoma of CNS, Von Hippel-Lindau Disease | Not applicable | Recruiting | Assistance Publique - Hôpitaux de Paris | 85 | 2023-01-16 | 2023-12-13 |
| Functional Navigation in Surgery of Cerebral Tumors and Vascular Malformations Functional navigation - Tumor, Brain, Arteriovenous Malformations | Not applicable | Suspended | Sklifosovsky Institute of Emergency Care | 50 | 2022-09-01 | 2025-05-16 |
| Assessing the Impact of Dosage Frequency of Propranolol on Sleep Patterns in Patients With Infantile Hemangiomas Propranolol three times a day, Propranolol twice a day, Timolol - Infantile Hemangioma | Phase 4 | Terminated | The University of Texas Health Science Center, Houston | 52 | 2022-06-23 | 2026-03-13 |
| Infantile Hemangioma With Minimal or Arrested Growth : Epidemiology, Clinical Characteristics and Evolution Hemangioma, Capillary | Completed | Central Hospital, Nancy, France | 224 | 2021-03-23 | 2021-10-18 | |
| Efficacy of Intralesional Bleomycin Alone and in Combination With Dexamethasone in Infantile Haemangiomas Comparison of intralesional injection of bleomycin alone and combined with injection dexamethasone - Comparison of Efficacy of Sclerotherapy in Infantile Hemangioma | Not applicable | Completed | King Edward Medical University | 114 | 2021-03-22 | 2023-10-12 |
| ''Efficacy of Propranolol in the Treatment of Infantile Hemangioma" Propranolol Therapy for Infantile Hemangioma - Infantile Hemangioma | Phase 2 | Unknown | Assiut University | 100 | 2021-01-01 | 2020-12-24 |
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Hemangioblastoma (16) · Hemangioma (13) · von Hippel-Lindau Disease (10) · Vascular Malformations (4) · Brain Neoplasms (3) · Carcinoma, Renal Cell (3) · Central Nervous System Neoplasms (3) · Meningioma (3) · Neoplasms (3) · Cholangiocarcinoma (2) · Cysts (2) · Hemangioma, Cavernous (2) · Neuroectodermal Tumors, Primitive (2) · Paraganglioma (2)
Neoplasms by Histologic Type (63) · Neoplasms, Vascular Tissue (63) · Neoplasms (60) · Hemangioma (50) · Congenital, Hereditary, and Neonatal Diseases and Abnormalities (21) · Nervous System Diseases (20) · Congenital Abnormalities (19) · Cardiovascular Diseases (18) · Vascular Diseases (14) · Genetic Diseases, Inborn (12) · Neoplasms by Site (12) · Neurocutaneous Syndromes (11) · Abnormalities, Multiple (10) · Angiomatosis (10)
Propranolol (8) · Timolol (7) · Lasers, Dye (3) · Atenolol (2) · Imiquimod (2) · Nadolol (2) · Population Groups (2) · Sunitinib (2) · 4-amino-5-fluoro-3-(5-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl)quinolin-2(1H)-one (1) · Adrenergic beta-Antagonists (1) · Alfentanil (1) · Amikacin (1) · Aminocaproic Acid (1) · Bevacizumab (1) · Bleomycin (1)
West China Hospital (6) · National Institute of Neurological Disorders and Stroke (NINDS) (3) · Assiut University (2) · M.D. Anderson Cancer Center (2) · Pierre Fabre Dermatology (2) · The Hospital for Sick Children (2) · University Hospital, Montpellier (2) · University of California, Irvine (2) · AFT Pharmaceuticals, Ltd. (1) · Ain Shams University (1) · Alice K. Gong (1) · Assistance Publique - Hôpitaux de Paris (1) · Assistance Publique Hopitaux De Marseille (1) · Auson Pharmaceuticals Inc. (1) · Bispebjerg Hospital (1)
United States (28) · China (12) · France (9) · Canada (5) · Spain (4) · Egypt (3) · Brazil (2) · Germany (2) · Italy (2) · Netherlands (2) · Poland (2) · Russia (2) · United Kingdom (2) · Australia (1) · Austria (1)
Eric Jonasch, MD (2) · Prashant Chittiboina, M.D. (2) · Adrienne Hammill, MD, PhD (1) · Albert C. Yan, MD (1) · Alexander Dmitriev, MD (1) · Alfons L. Krol, M.D. (1) · Alice K Gong, M.D. (1) · Alice K Gong, MD (1) · Beth Drolet, MD (1) · Camila MV Moniz, Doctor (1) · Catherine McCuaig, M.D. (1) · Chi Hornik, PharmD (1) · Christine Labreze, MD (1)
PMID 19419474, PMID 20598318, PMID 20828712, PMID 22105611, PMID 23301692, PMID 24579662, PMID 24614374, PMID 24949994, PMID 25693013, PMID 26039810, PMID 26813215, PMID 26926644, PMID 27062495, PMID 27522443, PMID 28137820, PMID 28290120, PMID 28779462, PMID 29084742, PMID 29271816, PMID 29435949, PMID 29571951, PMID 29677389, PMID 30584062, PMID 30790601, PMID 31317556, PMID 31548185, PMID 31814149, PMID 32324313, PMID 32497307, PMID 33029806, PMID 33118199, PMID 33856430, PMID 33903114, PMID 34302290, PMID 34747977, PMID 34783716, PMID 35275019, PMID 35370711, PMID 35491971, PMID 35661809, PMID 35751738, PMID 37018064, PMID 37333396, PMID 38134265, PMID 38134268, PMID 38553990, PMID 38759778, PMID 39612031, PMID 40327835, PMID 40614265
2008 (1), 2025 (1), U01NS104157 (1)